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An Acute Respiratory Distress Syndrome Drug Development Collaboration Stimulated By The Virginia Drug Discovery Consortium, John S. Lazo, Ruben M.L. Colunga-Biancatelli, Pavel A. Solopov, John D. Catravas Jan 2023

An Acute Respiratory Distress Syndrome Drug Development Collaboration Stimulated By The Virginia Drug Discovery Consortium, John S. Lazo, Ruben M.L. Colunga-Biancatelli, Pavel A. Solopov, John D. Catravas

Bioelectrics Publications

The genesis of most older medicinal agents has generally been empirical. During the past one and a half centuries, at least in the Western countries, discovering and developing drugs has been primarily the domain of pharmaceutical companies largely built upon concepts emerging from organic chemistry. Public sector funding for the discovery of new therapeutics has more recently stimulated local, national, and international groups to band together and focus on new human disease targets and novel treatment approaches. This Perspective describes one contemporary example of a newly formed collaboration that was simulated by a regional drug discovery consortium. University of Virginia, …


Blockchain-Based Digital Trust Mechanism: A Use Case Of Cloud Manufacturing Of Lds Syringes For Covid-19 Vaccination, Trupti Rane, Jingwei Huang Jan 2022

Blockchain-Based Digital Trust Mechanism: A Use Case Of Cloud Manufacturing Of Lds Syringes For Covid-19 Vaccination, Trupti Rane, Jingwei Huang

Engineering Management & Systems Engineering Faculty Publications

Trust is essential in the digital world. It is a critical task to build digital trust for the ongoing digital engineering transformation. Aiming at developing a blockchain-based digital trust mechanism for Cloud Manufacturing or Manufacturing-as-a-Service (MaaS), in this paper, we use the manufacturing of low dead space (LDS) medical syringes through Cloud Manufacturing as a motivating scenario to develop a basic framework. To meet the need of optimally saving COVID-19 vaccine doses to save more lives, the medical device manufacturing community needs to make a swift move to meet the surged need for LDS syringes. Cloud Manufacturing is a form …


Why Do Family Members Reject Ai In Health Care? Competing Effects Of Emotions, Eun Hee Park, Karl Werder, Lan Cao, Balasubramaniam Ramesh Jan 2022

Why Do Family Members Reject Ai In Health Care? Competing Effects Of Emotions, Eun Hee Park, Karl Werder, Lan Cao, Balasubramaniam Ramesh

Information Technology & Decision Sciences Faculty Publications

Artificial intelligence (AI) enables continuous monitoring of patients’ health, thus improving the quality of their health care. However, prior studies suggest that individuals resist such innovative technology. In contrast to prior studies that investigate individuals’ decisions for themselves, we focus on family members’ rejection of AI monitoring, as family members play a significant role in health care decisions. Our research investigates competing effects of emotions toward the rejection of AI monitoring for health care. Based on two scenario-based experiments, our study reveals that emotions play a decisive role in family members’ decision making on behalf of their parents. We find …


Editorial: Leveraging Emerging Technology To Fight The Covid-19 Pandemic, Ling Li Jan 2021

Editorial: Leveraging Emerging Technology To Fight The Covid-19 Pandemic, Ling Li

Information Technology & Decision Sciences Faculty Publications

No abstract provided.


A Review On Covid-19 Related Research In Leading Information Systems Journals, Yuming He, Wenzhuo Li, Xin Tian, Yunfei Xing Jan 2021

A Review On Covid-19 Related Research In Leading Information Systems Journals, Yuming He, Wenzhuo Li, Xin Tian, Yunfei Xing

Information Technology & Decision Sciences Faculty Publications

To identify the key challenges, issues and opportunities affecting individuals, organizations, and society on coping with COVID-19, we reviewed extant research related to the COVID-19 pandemic in the leading information systems journals. Six major research themes and representative literature for each theme are identified by content analysis. The six major research themes include digital transformation, data visualization and artificial intelligence, infodemic and cybersecurity, IT governance, digital divide, and IS research direction in the post-pandemic period. Moreover, we discussed the challenges, current research, and opportunities related to each of the themes. The review provides a snapshot of IS literature on the …