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Opioid Adjunct Drug Therapy: Evaluating Effectiveness Using Text Analytics Of Real World Data, Michael Veronin, Robert P. Schumaker

Communications of the IIMA

Opioid analgesics continue to be the mainstay of pharmacologic treatment of moderate to severe pain. An adjunct is a drug that in its pharmacological characteristic is not identified primarily as an analgesic, but that has been found in clinical practice to have either an independent analgesic effect or additive analgesic properties when used with opioids. By using an adjunct to maximize the level of analgesia, the required opioid dosage may be reduced, together with concomitant adverse effects. BACKGROUND Real World Data (RWD) refers to data that describe observations in normal clinical practice obtained by any non- interventional methodology, such as …