Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 4 of 4
Full-Text Articles in Business
Research And Development Project Valuation And Licensing Negotiations At Phytopharm Plc, Pascale Crama, Bert De Reyck, Zeger Degraeve, Wang Chong
Research And Development Project Valuation And Licensing Negotiations At Phytopharm Plc, Pascale Crama, Bert De Reyck, Zeger Degraeve, Wang Chong
Research Collection Lee Kong Chian School Of Business
We describe a research and development project-valuation model developed for Phytopharm plc, a pharmaceutical development and functional food company based in Cambridgeshire, United Kingdom. Phytopharm uses the model to value the projects in its research and development portfolio, and in licensing negotiations with potential product development and marketing partners. We include different valuation methods, including net present value, decision analysis, and Monte Carlo simulation. We also consider the technological risks of product development, as well as the uncertainty of commercial success. In addition to determining a value for a product in development, the model proposes appropriate licensing contract structures. A …
Chaos And Convergence On Bucket Brigade Assembly Lines, John J. Bartholdi, Iii, Donald D. Eisenstein, Yun Fong Lim
Chaos And Convergence On Bucket Brigade Assembly Lines, John J. Bartholdi, Iii, Donald D. Eisenstein, Yun Fong Lim
Research Collection Lee Kong Chian School Of Business
One way to coordinate the efforts of workers along an assembly line that has fewer workers than work stations is to form a bucket brigade. Each worker in a bucket brigade simultaneously assembles a single item (an instance of the product) along the line. The worker carries the item from work station to work station until either he hands of his item to a downstream co-worker or he completes the work for his item. The worker then walks back to get another item, either from his co-worker upstream or from a buffer at the beginning of the line. The most …
Machine Scheduling Performance With Maintenance And Failure, Yunsong Guo, Andrew Lim, Brian Rodrigues, Shuang Yu
Machine Scheduling Performance With Maintenance And Failure, Yunsong Guo, Andrew Lim, Brian Rodrigues, Shuang Yu
Research Collection Lee Kong Chian School Of Business
In manufacturing control, machine scheduling research has mostly dealt with problems either without maintenance or with deterministic maintenance when no failure can occur. This can be unrealistic in practical settings. In this work, an experimental model is developed to evaluate the effect of corrective and preventive maintenance schemes on scheduling performance in the presence of machine failure where the scheduling objective is to minimize schedule duration. We show that neither scheme is clearly superior, but that the applicability of each depends on several system parameters as well as the scheduling environment itself. Further, we show that parameter values can be …
A Comparison Of Cross Training Policies In Different Job Shops, Kum Khiong Yang
A Comparison Of Cross Training Policies In Different Job Shops, Kum Khiong Yang
Research Collection Lee Kong Chian School Of Business
This research compares a set of cross-training policies represented by different numbers of cross-trained workers, additional skills per cross-trained worker, and additional machines. The policies are evaluated in job shops, represented by different efficiency losses, labour utilization, variability in processing times, and worker absenteeism. Our results show that adding one machine in each department and cross-training one or two workers from each department with one additional skill is generally sufficient to realize most of the benefits of cross-training. Cross-training is thus beneficial in most job shops, unless the cost of the minimal training and spare machines is high. Our results …