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Covid-19 And Management Scholarship: Lessons For Conducting Impactful Research, Gerard George, Gokhan Ertug, Jonathan P. Doh, Johanna Mair, Ajnesh Prasad Apr 2024

Covid-19 And Management Scholarship: Lessons For Conducting Impactful Research, Gerard George, Gokhan Ertug, Jonathan P. Doh, Johanna Mair, Ajnesh Prasad

Research Collection Lee Kong Chian School Of Business

The COVID-19 pandemic provided an opportunity for management scholars to address large-scale and complex societal problems and strive for greater practical and policy impact. A brief overview of the most-cited work on COVID-19 reveals that, compared with their counterparts in other disciplines, leading management journals and professional associations lagged in providing a platform for high-impact research on COVID-19. To help management research play a more active role in responding to similar global challenges in the future, we propose an integrative framework that emphasizes a phenomenon’s impact, the conditions that the phenomenon creates at multiple levels, and the responses of actors …


Effect Of The Announcement Of Human-To-Human Transmission On Teleconsultation Services In China During Covid-19, Mairehaba Maimaitiming, Jingui Xie, Zhichao Zheng, Yongjian Zhu Dec 2023

Effect Of The Announcement Of Human-To-Human Transmission On Teleconsultation Services In China During Covid-19, Mairehaba Maimaitiming, Jingui Xie, Zhichao Zheng, Yongjian Zhu

Research Collection Lee Kong Chian School Of Business

Objectives: Telemedicine enables patients to communicate with physicians effectively, especially during the coronavirus disease (COVID-19) pandemic. However, few studies have explored the use of online health care platforms for a comprehensive range of specialties during the COVID-19 pandemic. This study aimed to investigate how telemedicine services were affected by the announcement of human-to-human transmission in China. Methods: Telemedicine data from haodf.com in China were collected. A difference-in-differences analysis compared the number of telemedicine use and the number of active online physicians for different specialties in 2020 with the numbers in 2019, before and after the announcement of human-to-human transmission. Results: …


Not A Box Of Nuts And Bolts: Distribution Channels For Specialty Drugs?, Liang Xu, Vidya Mani, Hui Zhao Jul 2023

Not A Box Of Nuts And Bolts: Distribution Channels For Specialty Drugs?, Liang Xu, Vidya Mani, Hui Zhao

Research Collection Lee Kong Chian School Of Business

One of the most important trends in the pharmaceutical industry is the rapid growth of specialty drugs. Specialty drugs, mostly bio based, tend to be high risk, high priced, and more regulated than traditional drugs, resulting in unprecedented challenges in distribution. Such challenges lead to the emergence of specialty distributors (SDs), which, compared with traditional wholesalers (WSs), represent a more controlled channel and carry a smaller variety of drugs. Due to the risky nature of specialty drugs, manufacturers must consider the trade-off between access and control in determining whether to use SDs (partially or exclusively). Using a unique dataset assembled …


Care Labour Shortage Needs A Cure, Not More Band-Aids, Yasmin Y. Ortiga Jul 2023

Care Labour Shortage Needs A Cure, Not More Band-Aids, Yasmin Y. Ortiga

Asian Management Insights

Retaining care workers will become more difficult for Asia’s ageing economies.


Covid Time: How Quarantine Affects Feelings Of Elapsed Time, Minju Han, Guy Voichek, Gal Zauberman Apr 2023

Covid Time: How Quarantine Affects Feelings Of Elapsed Time, Minju Han, Guy Voichek, Gal Zauberman

Research Collection Lee Kong Chian School Of Business

The lockdowns imposed in response to the COVID-19 pandemic abruptly upended people's lives and daily structure. In this survey of 1,506 Americans conducted in June 2020, we test how quarantine affects feelings of elapsed time (the subjective temporal distance from an event). We find that feelings of elapsed time are determined either by how people spent their time in quarantine or by how much time since an event was spent in quarantine, depending on whether people are still in quarantine at the time of evaluation. Specifically, whether people quarantined alone and the extent to which they maintained a temporal structure …


“High” Innovators? Marijuana Legalization And Regional Innovation, Stephanihe Cheng, Pengkai Lin, Yinliang Tan, Yuchen Zhang Mar 2023

“High” Innovators? Marijuana Legalization And Regional Innovation, Stephanihe Cheng, Pengkai Lin, Yinliang Tan, Yuchen Zhang

Research Collection School Of Accountancy

The past three decades have witnessed a tremendous shift in public health policies towards marijuana legalization in the U.S. Adopting the process-based view of innovation, we hypothesize that marijuana's increased use and related consequences after its legalization affect innovators’ behavior and social environment during the innovation process, which in turn impacts regional innovation. Utilizing the staggered adoption of medical marijuana laws by 20 states between 1996 and 2013 as a quasi-experimental setting, we find that legalizing medical marijuana reduces the overall output of regional innovation, as proxied by patents’ total forward-citation count aggregated by innovator location. Further analyses decomposing the …


Creating The Capacity For Digital Government, Cheow Hoe Chan, Steven M. Miller Mar 2023

Creating The Capacity For Digital Government, Cheow Hoe Chan, Steven M. Miller

Asian Management Insights

This article explains how a well-thought-out data policy, supported by a tech stack and cloud infrastructure, an agile way of working, and coordinated whole-of-government leadership, are fundamental to successful government digital transformation efforts, as exemplified by the Singapore government’s digital journey. As part of explaining how to create the capacity for digital government, the main sections of this article cover:

  • The origins of GovTech
  • How thinking big, starting small and acting fast is a practical strategy for organisational learning
  • The importance of horizontal platforms and other enablers of a horizontal approach
  • Data architecture and policy
  • “Shifting left” with internal technology …


Marijuana Liberalization And Public Finance: A Capital Market Perspective On The Passage Of Medical Use Laws, Stephanie F. Cheng, Gus De Franco, Pengkai Lin Feb 2023

Marijuana Liberalization And Public Finance: A Capital Market Perspective On The Passage Of Medical Use Laws, Stephanie F. Cheng, Gus De Franco, Pengkai Lin

Research Collection School Of Accountancy

We find that the staggered passage of state-level laws that legalize marijuana for medical use increases states' borrowing costs by 7–9 basis points. Consistent with economic theory on substance use suggesting that marijuana legalization increases local consumption of the drug (by expanding its availability and reducing its perceived risks), we predict and find that increased consumption represents an important mechanism that explains the higher state bond spreads. We also show that following such laws’ passage, states incur higher marijuana-consumption-related expenditures, including for police, corrections, and public welfare.


Can Big Data Cure Risk Selection In Healthcare Capitation Program? A Game Theoretical Analysis, Zhaowei She, Turgay Ayer, Daniel Montanera Nov 2022

Can Big Data Cure Risk Selection In Healthcare Capitation Program? A Game Theoretical Analysis, Zhaowei She, Turgay Ayer, Daniel Montanera

Research Collection Lee Kong Chian School Of Business

Problem definition: This paper analyzes a market design problem in Medicare Advantage (MA), the largest risk-adjusted capitation payment program in the U.S. healthcare market. Evidence exists that the current MA capitation payment program unintentionally incentivizes health plans to cherry pick profitable patient types, which is referred to as “risk selection”. However, the root causes of the risk selection are not comprehensively understood, which we study in this paper. Academic / Practical Relevance: The existing literature primarily attributes the observed risk selection in MA market to data limitations and low explanatory power (e.g. low R2) of the current risk adjustment design. …


Making Virtual Project-Based Learning Work During The Covid-19 Pandemic, Yuanto Kusnadi, Gary Pan, Shankararaman, Venky Oct 2022

Making Virtual Project-Based Learning Work During The Covid-19 Pandemic, Yuanto Kusnadi, Gary Pan, Shankararaman, Venky

Research Collection School Of Accountancy

Project-based learning is an increasingly popular pedagogical approach in university education shown to be effective in fostering problem-solving, analytical, design thinking and teamwork skills. The COVID-19 pandemic has led to universities pivoting from project-based learning (PBL) in the classroom to a virtual learning environment. By examining local student consulting courses conducted virtually in a Singapore University (UNIS) during the COVID-19 pandemic, this study aims to address the knowledge gap in the PBL literature by identifying the roles played by digital literacy - in utilising the digital tools that support virtual learning, in a virtual learning environment. The study also serves …


Agility And Focus Save The Day, Eddy Kusnadi Sariaatmadja, Chin Tiong Tan May 2022

Agility And Focus Save The Day, Eddy Kusnadi Sariaatmadja, Chin Tiong Tan

Asian Management Insights

Eddy Kusnadi Sariaatmadja, Founder and President Commissioner of Indonesia’s PT Elang Mahkota Teknologi (Emtek), tells Tan Chin Tiong how the company not only survived, but thrived during the COVID-19 pandemic.


The Resilience Of Diversified Clusters: Reconfiguring Commodity Networks In Rural China During The Covid-19 Pandemic, Zhanping Hu, Qian Forrest Zhang Mar 2022

The Resilience Of Diversified Clusters: Reconfiguring Commodity Networks In Rural China During The Covid-19 Pandemic, Zhanping Hu, Qian Forrest Zhang

Research Collection School of Social Sciences

We conceptualize typical rural communities in China as diversified economic clusters. In normal times, economic actors in these communities rarely cooperate with each other, but are integrated into separate commodity chains. These “diversified clusters”, however, show resilience and flexibility when an external shock—the COVID-19 pandemic—disrupts the spatial connections throughout the existing commodity chains. In this study, we use primary field data collected from one typical rural community in Northern China to show how economic diversity, aided by social networks and space-shrinking technologies, allowed for the vertical commodity chains to be reconfigured temporarily into localized horizontal commodity networks to cope with …


On The Test Accuracy And Effective Control Of The Covid-19 Pandemic: A Case Study In Singapore, Guang Cheng, Sarah Yini Gao, Yancheng Yuan, Chenxiao Zhang, Zhichao Zheng Mar 2022

On The Test Accuracy And Effective Control Of The Covid-19 Pandemic: A Case Study In Singapore, Guang Cheng, Sarah Yini Gao, Yancheng Yuan, Chenxiao Zhang, Zhichao Zheng

Research Collection Lee Kong Chian School Of Business

This study examines the impact of coronavirus disease 2019 (COVID-19) test accuracy (i.e., sensitivity and specificity) on the progression of the pandemic under two scenarios of limited and unlimited test capacity. We extend the classic susceptible–exposed–infectious–recovered model to incorporate test accuracy and compare the progression of the pandemic under various sensitivities and specificities. We find that high-sensitivity tests effectively reduce the total number of infections only with sufficient testing capacity. Nevertheless, with limited test capacity and a relatively high cross-infection rate, the total number of infected cases may increase when sensitivity is above a certain threshold. Despite the potential for …


Weighting Admission Scores To Balance Predictiveness-Diversity: The Pareto-Optimization Approach, Filip Lievens, Paul R. Sackett, Wilfried De Corte Feb 2022

Weighting Admission Scores To Balance Predictiveness-Diversity: The Pareto-Optimization Approach, Filip Lievens, Paul R. Sackett, Wilfried De Corte

Research Collection Lee Kong Chian School Of Business

Context: Although many medical schools seek to improve diversity, they grapple with the challenge of how to weight the scores of different admission methods to achieve a balance between obtaining high predictiveness and ensuring diversity in the selected student pool. Yet, in large-scale employment settings, substantial progress has been made on this front: Pareto-optimization has been introduced as an elegant statistical tool to assist decision makers in determining the weights assigned to selection methods in advance (before the selection has taken place) so that a selection system is designed to achieve an optimal balance as reflected by the trade-off that …


Comparison Of The Mental Burden On Nursing Care Providers With And Without Mat-Type Sleep State Sensors At A Nursing Home In Tokyo, Japan: Quasi-Experimental Study, Sakiko Itoh, Hwee-Pink Tan, Kenichi Kudo, Yasuko Ogata Jan 2022

Comparison Of The Mental Burden On Nursing Care Providers With And Without Mat-Type Sleep State Sensors At A Nursing Home In Tokyo, Japan: Quasi-Experimental Study, Sakiko Itoh, Hwee-Pink Tan, Kenichi Kudo, Yasuko Ogata

Research Collection School Of Computing and Information Systems

Background: Increasing need for nursing care has led to the increased burden on formal caregivers, with those in nursing homes having to deal with exhausting labor. Although research activities on the use of internet of things devices to support nursing care for older adults exist, there is limited evidence on the effectiveness of these interventions among formal caregivers in nursing homes. Objective: This study aims to investigate whether mat-type sleep state sensors for supporting nursing care can reduce the mental burden of formal caregivers in a nursing home. Methods: This was a quasi-experimental study at a nursing home in Tokyo, …


The Moderating Effect Of Solar Radiation On The Association Between Human Mobility And Covid-19 Infection In Europe, Wenyu Zhao, Yongjian Zhu, Jingui Xie, Zhichao Zheng, Haidong Luo, Oon Cheong Ooi Jan 2022

The Moderating Effect Of Solar Radiation On The Association Between Human Mobility And Covid-19 Infection In Europe, Wenyu Zhao, Yongjian Zhu, Jingui Xie, Zhichao Zheng, Haidong Luo, Oon Cheong Ooi

Research Collection Lee Kong Chian School Of Business

The novel coronavirus disease 2019 (COVID-19) has caused a global pandemic. Some studies have suggested a negative association between sunlight intensity and COVID-19 infection, alluding to the belief that it might be safe to go out on sunny days. This paper examined whether solar radiation mitigated the association between human mobility and COVID-19 infection in Europe using a dynamic panel data model to investigate the effect of human mobility, solar radiation, and their interaction on COVID-19 infection. The results revealed that outgoing mobility was positively correlated and solar radiation was negatively correlated with COVID-19 infection at lag levels of 1, …


Accounting And Finance Lessons In The Time Of Covid-19: Views From The Pacific Basin: Part 2, Kuan Yong David Ding, Julie Harrison, Martien Lubberink, Chris Van Staden Nov 2021

Accounting And Finance Lessons In The Time Of Covid-19: Views From The Pacific Basin: Part 2, Kuan Yong David Ding, Julie Harrison, Martien Lubberink, Chris Van Staden

Research Collection Lee Kong Chian School Of Business

The global COVID-19 pandemic is now in its second year, and we are fast approaching the third. The year 2021 has brought some hope that vaccination will lead to the end of the pandemic. But it has also brought a more infectious variant of COVID-19 and multiple waves of surging cases that show no immediate sign of disappearing. As the pandemic continues to impact global societies and economies, it is imperative that we study its impact to try and understand how it will affect us in both the short-term and long-term. While the longer-term impacts are still unknown, there is …


Close Friendships At Work Are Lifelines That Have Frayed During The Pandemic, Kenneth Tai Oct 2021

Close Friendships At Work Are Lifelines That Have Frayed During The Pandemic, Kenneth Tai

Research Collection Lee Kong Chian School Of Business

We have gone from having lunch with colleagues and meeting after work to eating hurriedly at our desks at home. The change in relationships at work also affects our productivity, argues SMU’s Kenneth Tai.


The 2021 Ipr Future Of Communications In Asia Report, Tina Mccorkindale, Sarah Crawshaw, Su Lin Yeo, Stephen Thomas, Alexis B. Fitzsimmons, Pang, A. Sep 2021

The 2021 Ipr Future Of Communications In Asia Report, Tina Mccorkindale, Sarah Crawshaw, Su Lin Yeo, Stephen Thomas, Alexis B. Fitzsimmons, Pang, A.

Research Collection Lee Kong Chian School Of Business

The communication function within Asian-headquartered organizations is undergoing significant growth and changes that will be pivotal for its future success, according to a new Institute for Public Relations (IPR) research report. The “IPR Future of Communications in Asia” research report investigates key changes that will impact the future of the communications function. The analysis is based on interviews with 30 senior communications executives based in Asia in a variety of industries from 2019 to 2020, and three focus groups with nearly 20 senior communication leaders in late 2020.


Information Avoidance And Medical Screening: A Field Experiment In China, Yufeng Li, Juanjuan Meng, Changcheng Song, Kai Zheng Jul 2021

Information Avoidance And Medical Screening: A Field Experiment In China, Yufeng Li, Juanjuan Meng, Changcheng Song, Kai Zheng

Research Collection Lee Kong Chian School Of Business

Will individuals, especially high-risk individuals, avoid a disease test because of information avoidance? We conduct a field experiment to investigate this issue. We vary the price of a diabetes test (price experiment) and offer both a diabetes test and a cancer test (disease experiment) after eliciting participants’ subjective beliefs about their disease risk. We find evidence that, first, some people avoid the test even when there is neither a monetary nor a transaction cost, and second, both low- and high-risk individuals select out of the test as the price increases. We explain our findings using three classes of models of …


Analytics For Hospital Resource Planning: Two Case Studies, Jingui Xie, Weifen Zhuang, Marcus Ang, Mabel C. Chou, Li Luo, David D. Yao Jun 2021

Analytics For Hospital Resource Planning: Two Case Studies, Jingui Xie, Weifen Zhuang, Marcus Ang, Mabel C. Chou, Li Luo, David D. Yao

Research Collection Lee Kong Chian School Of Business

Using real data and process flows from two large hospitals (in Singapore and in Chengdu, China) as cases, we illustrate how to apply certain modeling and optimization techniques, along with simulation as a validation tool, to hospital resource planning problems. We demonstrate how these simple analytical tools can help achieve significant improvements in both patient service and resource utilization, and without the need to increase the overall level of existing capacities. Two resource planning problems are studied in detail, one concerns the re-balancing of bed capacities among various wards, and the other addresses the allocation of medical diagnostic resource among …


Divide And Conquer: A Hygienic, Efficient, And Reliable Assembly-Line For Housekeeping, Xiao Alison Chen, Rowan Wang, Jianghua Zhang Jun 2021

Divide And Conquer: A Hygienic, Efficient, And Reliable Assembly-Line For Housekeeping, Xiao Alison Chen, Rowan Wang, Jianghua Zhang

Research Collection Lee Kong Chian School Of Business

Problem definition: This work focuses on the hotel housekeeping process. In a field study, a possible channel of disease transmission between consecutive guests in hotel rooms is revealed. In order to prevent the transmission, an innovative assembly-line housekeeping method is developed. Academic/practical relevance: The transmission of infectious diseases during hotel stays (e.g., by touching unclean towels or bed linens) has been reported globally. Under the current COVID-19 pandemic, having contact with saliva or mucus left by an infected person could cause infection. The standard housekeeping process used by the majority of hotels leaves a channel for new towels and bed …


Essays On Predictive And Prescriptive Analytics For Risk Monitoring And Population Screening In Healthcare Management, Yan He Jun 2021

Essays On Predictive And Prescriptive Analytics For Risk Monitoring And Population Screening In Healthcare Management, Yan He

Dissertations and Theses Collection (Open Access)

Due to increased aging populations and changes in lifestyles, we have witnessed an increased prevalence of various chronic and acute diseases and a drastic rise in healthcare expenditures in recent years. It is of paramount importance for public health to promote regular screening and close monitoring to detect the early onset of diseases. On the other hand, the increasing availability of healthcare data and advancement in data analytics offer a huge potential to facilitate this goal. We can analyze the vast amount of data and recommend more personalized diagnostic tests after receiving results and signals from screening tests and monitoring …


Balancing Social Impact And Business Outcomes In Turbulent Times, Jaime Augusto Zobel De Ayala, Chin Tiong Tan May 2021

Balancing Social Impact And Business Outcomes In Turbulent Times, Jaime Augusto Zobel De Ayala, Chin Tiong Tan

Asian Management Insights

Jaime Augusto Zobel de Ayala, Chairman of Ayala Corporation, talks about learning and recovering from Covid-19’s impact with Tan Chin Tiong.


Behavioural Incentivization In Healthcare Operations, Nicholas Teck Boon Yeo May 2021

Behavioural Incentivization In Healthcare Operations, Nicholas Teck Boon Yeo

Dissertations and Theses Collection (Open Access)

Common across current research in healthcare operations is the conclusion that there exist many inefficiencies in today’s healthcare systems. Governments and healthcare organisations have sought to address these inefficiencies through the introduction of new policies and operational procedures or by relying on incentives to encourage specific behaviour. However, despite these attempts to reduce inefficiencies in the healthcare systems, the problem persists and is further exacerbated by growing medical complexities coupled with a rapidly ageing population. Against this backdrop, this dissertation investigates two issues within healthcare operations: (i) colorectal cancer (CRC) screening adherence, and (ii) blood donor management. A distinguishing feature …


Digital Sustainability And Its Implications For Finance And Climate Change, Gerard George, Simon J.D. Schillebeeckx Apr 2021

Digital Sustainability And Its Implications For Finance And Climate Change, Gerard George, Simon J.D. Schillebeeckx

Research Collection Lee Kong Chian School Of Business

As the pandemic forced the entire world to a virtual standstill, nature revived a little. The US emitted 10.3% less CO2 in 2020 than in 2019 and other regions similarly experienced emission declines. Depending on the source, global carbon emissions were down between 4 and 8% in 2020.2 Consumers globally have expressed more concern about sustainability, an observation confirmed by large survey research by Accenture, Kantar, Boston Consulting Group (BCG), and Ipsos.3 In its latest Emissions Gap Report4 , the UN Environment Programme (UNEP) explicitly connected the pandemic to climate change, nature loss, and pollution. Besides the acceleration of business …


Tips For Sme Transformation Amid Covid-19 Pandemic, Siow-Heng Ong Apr 2021

Tips For Sme Transformation Amid Covid-19 Pandemic, Siow-Heng Ong

Research Collection Lee Kong Chian School Of Business

The author shared that following the economic downturn in 2020, revival in 2021 can only be very gradual. SMEs in different sectors of the economy face different challenges and have different options for response. Overall, SMEs are hopeful rather than confident. SMEs are generally hoping to manage cash flow and stretch their current funds for immediate business sustainability. Inevitably, their focus is on meeting critical business needs. Turnover and profits are not expected to return to pre-pandemic levels so any increase in hiring or other planning for the future will be slight. He suggested that for pragmatic managers of SMEs …


Cohesion, Covid-19 And Contemporary Challenges To Globalization, Andrew Delios, Gordon Perchthold, Alex Capri Apr 2021

Cohesion, Covid-19 And Contemporary Challenges To Globalization, Andrew Delios, Gordon Perchthold, Alex Capri

Research Collection Lee Kong Chian School Of Business

In the years preceding the COVID-19 pandemic, the decades-long, pan-continental globalization consensus was being questioned. In our view, the pandemic has accelerated the rate at which the globalization consensus is being defied. To better understand the implications of this defiance, we turn to research on people, organizations and international competition to see whether this defiance weakens the cohesion needed to keep globalization moving apace. People and organizations create cohesive forces that can link and constrain the differences that are encountered when people and organizations move across international borders. Meanwhile, the nature of international competition, particularly as connected to the level …


Covid-19 And The Workplace: Implications, Issues, And Insights For Future Research And Action, Kevin M. Kniffin, Jayanth Narayanan, Frederik Anseel, John Antonakis, Susan P. Ashford, Arnold B. Bakker, Peter Bamberger, Hari Bapuji, Devasheesh P. Bhave, Virginia K. Choi, Stefanie J. Creary, Evangelia Demerouti, Francis J. Flynn, Michele J. Gelfand, Lindred L. Greer, Gary Johns, Selin Kesebir, Peter G. Klein, Sun Young Lee, Hakan Ozcelik, Jennifer Louise Petriglieri, Nancy P. Rothbard, Cort W. Rudolph, Jason D. Shaw, Nina Sirola Jan 2021

Covid-19 And The Workplace: Implications, Issues, And Insights For Future Research And Action, Kevin M. Kniffin, Jayanth Narayanan, Frederik Anseel, John Antonakis, Susan P. Ashford, Arnold B. Bakker, Peter Bamberger, Hari Bapuji, Devasheesh P. Bhave, Virginia K. Choi, Stefanie J. Creary, Evangelia Demerouti, Francis J. Flynn, Michele J. Gelfand, Lindred L. Greer, Gary Johns, Selin Kesebir, Peter G. Klein, Sun Young Lee, Hakan Ozcelik, Jennifer Louise Petriglieri, Nancy P. Rothbard, Cort W. Rudolph, Jason D. Shaw, Nina Sirola

Research Collection Lee Kong Chian School Of Business

COVID-19’s impacts on workers and workplaces across the globe have been dramatic. We present a broad review of prior research rooted in work and organizational psychology, and related fields, for making sense of the implications for employees, teams, and work organizations. Our review and preview of relevant literatures focuses on: (i) emerging changes in work practices (e.g., working from home, virtual teams) and (ii) economic and social psychological impacts (e.g, unemployment, mental well-being). In addition, we examine the potential moderating factors of age, race and ethnicity, gender, family status, personality, andcultural differences to generate disparate effects. Illustrating the benefits of …


Inducing Compliance With Postmarket Studies For Drugs Under Fda's Accelerated Approval Pathway, Liang Xu, Hui Zhao, Nicholas C. Petruzzi Jan 2021

Inducing Compliance With Postmarket Studies For Drugs Under Fda's Accelerated Approval Pathway, Liang Xu, Hui Zhao, Nicholas C. Petruzzi

Research Collection Lee Kong Chian School Of Business

Problem definition: In 1992, the Food and Drug Administration (FDA) instituted the accelerated approval pathway (AP) to allow promising drugs to enter the market based on limited evidence of efficacy, thereby permitting manufacturers to verify true clinical benefits through postmarket studies. However, most postmarket studies have not been completed as promised. We address this noncompliance problem. Academic/practical relevance: The prevalence of this noncompliance problem poses considerable public health risk, thus compromising the original purpose of a well-intentioned AP initiative. We provide an internally consistent and implementable solution to the problem through a comprehensive analysis of the myriad complicating factors and …