Open Access. Powered by Scholars. Published by Universities.®
- Keyword
Articles 1 - 3 of 3
Full-Text Articles in Business
Knowledge Discovery And Modeling In Genomic Databases, Michael M. Yin
Knowledge Discovery And Modeling In Genomic Databases, Michael M. Yin
Dissertations
This dissertation research is targeted toward developing effective and accurate methods for identifying gene structures in the genomes of high eukaryotes, such as vertebrate organisms. Several effective hidden Markov models (HMMs) are developed to represent the consensus and degeneracy features of the functional sites including protein-translation start sites, mRNA splicing junction donor and acceptor sites in vertebrate genes. The HMM system based on the developed models is fully trained using an expectation maximization (EM) algorithm and the system performance is evaluated using a 10-way cross-validation method. Experimental results show that the proposed HMM system achieves high sensitivity and specificity in …
Development And Characterization Of Methodology And Technology For The Alignment Of Fmri Time Series, Carlo Ciulla
Development And Characterization Of Methodology And Technology For The Alignment Of Fmri Time Series, Carlo Ciulla
Dissertations
This dissertation has developed, implemented and tested a novel computer based system (AUTOALIGN) that incorporates an algorithm for the alignment of functional Magnetic Resonance Image (fMRI) time series. The algorithm assumes the human brain to be a rigid body and computes a head coordinate system on the basis of three reference points that lie on the directions correspondent to two of the eigenvectors of inertia of the volume, at the intersections with the head boundary. The eigenvectors are found weighting the inertia components with the voxel's intensity values assumed as mass. The three reference points are found in the same …
Collaborative Problem Solving And Program Development Model, Joanna Defranco-Tommarello
Collaborative Problem Solving And Program Development Model, Joanna Defranco-Tommarello
Dissertations
A model to enhance collaborative problem solving and program development is presented. The collaborative model is a detailed cognitive model that takes into consideration the cognitive and social activities that occur during collaborative problem solving and program development. The cognitive activities required for collaborative problem solving and program development are identified and integrated into a six-stage model. An extensive literature review in the associated fields is presented to show the need for the model described in this dissertation. In addition, a comprehensive study of tools to support collaboration during problem solving and program development was also performed as well as …