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Theory And Practice Of Supply Chain Synchronization, Michael Prokle
Theory And Practice Of Supply Chain Synchronization, Michael Prokle
Doctoral Dissertations
In this dissertation, we develop strategies to synchronize component procurement in assemble-to-order (ATO) production and overhaul operations. We focus on the high-tech and mass customization industries which are not only considered to be very important to create or keep U.S. manufacturing jobs, but also suffer most from component inventory burden. In the second chapter, we address the deterministic joint replenishment inventory problem with batch size constraints (JRPB). We characterize system regeneration points, derive a closed-form expression of the average product inventory, and formulate the problem of finding the optimal joint reorder interval to minimize inventory and ordering costs per unit …
Personalized Decision Modeling For Intervention And Prevention Of Cancers, Fan Wang
Personalized Decision Modeling For Intervention And Prevention Of Cancers, Fan Wang
Graduate Theses and Dissertations
Personalized medicine has been utilized in all stages of cancer care in recent years, including the prevention, diagnosis, treatment and follow-up. Since prevention and early intervention are particularly crucial in reducing cancer mortalities, personalizing the corresponding strategies and decisions so as to provide the most appropriate or optimal medical services for different patients can greatly improve the current cancer control practices. This dissertation research performs an in-depth exploration of personalized decision modeling of cancer intervention and prevention problems. We investigate the patient-specific screening and vaccination strategies for breast cancer and the cancers related to human papillomavirus (HPV), representatively. Three popular …