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2010

American Studies

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Articles 1 - 30 of 415

Full-Text Articles in Arts and Humanities

1,2,3,4-Tetrahydroacridones As Potential Inhibitors Of Atovaquone-Resistant And Atovaquone- Susceptible P. Falciparum Isolates Tm90-C2b And W2, Lisa Luong Dec 2010

1,2,3,4-Tetrahydroacridones As Potential Inhibitors Of Atovaquone-Resistant And Atovaquone- Susceptible P. Falciparum Isolates Tm90-C2b And W2, Lisa Luong

Outstanding Honors Theses

Malaria is one of the most significant parasitic diseases affecting mankind today, exceeding 200 million annual cases worldwide1. This disease has been a serious issue due to developed resistance to commonly available antimalarial drugs including atovaquone and artemisinin2, the most relevant modern treatment (figure 1.1). This project focuses on the preparation of 1,2,3,4- tetrahydroacridones (figure 1.2) that can be tested for their activity against P. falciparum isolates TM90-C2B (an atovaquone-resistant parasitic strain) and W2 (an atovaquone-susceptible parasite). In the past, studies have shown that endochins (4(1H)-quinolones) 3 and acridines (figure 1.1) have been found to exhibit antimalarial activity4. The research …


Planning To Make A Difference: A Retrospective Account On Learning How To Organize, Christina Gomez Dec 2010

Planning To Make A Difference: A Retrospective Account On Learning How To Organize, Christina Gomez

Outstanding Honors Theses

No abstract provided.


Robertson, J. Lee, B. 1922 (Fa 535), Manuscripts & Folklife Archives Dec 2010

Robertson, J. Lee, B. 1922 (Fa 535), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid only for Folklife Archives Project 535. Interview with J. Lee Robertson conducted by Kenneth Hines and Gil Calhoun in Bowling Green, Kentucky. Robertson reminisces about the U.S. Army during World war II and his long association with Western Kentucky University.


Davis, Nathan William (Fa 534), Manuscripts & Folklife Archives Dec 2010

Davis, Nathan William (Fa 534), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid only for Folklife Archives Project 534. Folklore material classified by genre. Information collected by Nathan William Davis related to folklore genres for a folk studies class at Western Kentucky University.


Sullivan, Brendan J. (Fa 533), Manuscripts & Folklife Archives Dec 2010

Sullivan, Brendan J. (Fa 533), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid and full text (click on "Additional Files" below) for Folklife Archives Project 533. Folklore material classified by genre. Information collected by Brendan J. Sullivan related to folklore genres for a folk studies class at Western Kentucky University.


The Pragmatic Influences On Thou And Ye In Some Middle English Romances, Aislinn Meyer Dec 2010

The Pragmatic Influences On Thou And Ye In Some Middle English Romances, Aislinn Meyer

Outstanding Honors Theses

The standard explanation of the semantics of power and solidarity for second person Middle English pronoun choice, advanced by Roger Brown and Albert Gilman and accepted by many Middle English scholars since, has proven insufficient to explain many choices between thou and ye that fictional characters make. This paper applies the discourse theories of pragmatics and politeness, developed by Penelope Brown and Stephen C. Levinson, to the relatively untouched data set of non-Chaucerian romances in order to account for some of those anomalies. By examining the pronouns of address in Floris and Blancheflour, Havelok the Dane, Ywain and Gawain, …


Design, Synthesis And Sar Of A New Class Of Small Molecule Inhibitors Of Β-Secretase., Jordan M. Anderson Dec 2010

Design, Synthesis And Sar Of A New Class Of Small Molecule Inhibitors Of Β-Secretase., Jordan M. Anderson

Outstanding Honors Theses

β-Secretase is the enzyme responsible for the Amyloid-β plaques found in Alzheimer’s disease. Inhibition of this enzyme should prove to be very useful in combating Alzheimer’s disease by preventing this build-up. After a computational screening of the NCID-2 library a molecule was found to possess a 2- propanol structure with aromatic groups on either side. This moiety was replicated by a combinatorial library of 150 compounds. These compounds were screened initially against β-secretase at 100, 50, and then 25 μM to narrow down to 17 structures showing 50% inhibition at 25 μM. The IC50 for each of the 17 molecules …


Shift To Cesareans As Preferred Birthing Method: Implications, Risks, And Recommendations, Elizabeth Angelica Bernstein Dec 2010

Shift To Cesareans As Preferred Birthing Method: Implications, Risks, And Recommendations, Elizabeth Angelica Bernstein

Outstanding Honors Theses

No abstract provided.


Regulation Of Claudin-1 Expression Via Activation Of Ron Tyrosine Kinase And Transforming Growth Factor-Beta Signaling Pathways In Ovarian Carcinoma, Saya Karim Dec 2010

Regulation Of Claudin-1 Expression Via Activation Of Ron Tyrosine Kinase And Transforming Growth Factor-Beta Signaling Pathways In Ovarian Carcinoma, Saya Karim

Outstanding Honors Theses

Epithelial ovarian carcinoma is the most common cause of death among gynecologic malignancies in the United States. In the U.S., more than 21,000 women will be diagnosed with ovarian cancer and about 15,000 women will die of the disease this year alone. Although migration and invasion play key roles in tumor progression, the specific molecular events leading to dissemination of ovarian tumor cells have not been well delineated. Tight junctions are an integral component of epithelial junction complexes, which play a vital role in maintaining epithelial integrity and cell polarity. Disruption of tight junctions is a hallmark of epithelial cancer …


Isolation And Identification Of Eastern Equine Encephalitis Virus In Mosquito Pools, Timothy Bender Dec 2010

Isolation And Identification Of Eastern Equine Encephalitis Virus In Mosquito Pools, Timothy Bender

Outstanding Honors Theses

The Eastern Equine Encephalitis Virus (EEEV) is transmitted to humans by mosquitoes of many genera. This virus has a high mortality rate and frequent life-altering complications for survivors of infection. The current practice for isolating and identifying the EEEV has been restricted to testing pools of 50 or less mosquitoes. A procedure for simulating one infected mosquito in a pool of 100 was established and tested. Data collected shows the threshold pool size can be increased to 100 without loss of specificity or accuracy. This increased will be met with many benefits including economic savings and increased time efficiency.


An Approach To Mitigating Excess Medical Waste, Ryan M. Kania, Jordan B. Markel Dec 2010

An Approach To Mitigating Excess Medical Waste, Ryan M. Kania, Jordan B. Markel

Outstanding Honors Theses

We present a literature-based review on global health disparities and a health economics perspective on utilizing low cost interventions to improve these disparities. We then introduce the need for a non-for profit organization that specializes in excess medical waste as a low cost intervention to empower targeted communities and improve global health disparities while decreasing the burden of medical waste. Medical waste is defined and a literature-based review is presented on the current body of knowledge concerning medical waste such as how much exists and why it exists. We then present a research study survey that will be executed to …


Rothfuss, Erik, B. 1987 (Fa 488), Manuscripts & Folklife Archives Nov 2010

Rothfuss, Erik, B. 1987 (Fa 488), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid and full text (click on "Additional Files" below) for Folklife Archives Project 488. Information collected by Erik Rothfuss related to folklore genres for a folk studies class at Western Kentucky University.


Loveall, Sandra Kaye, B. 1964 (Fa 486), Manuscripts & Folklife Archives Nov 2010

Loveall, Sandra Kaye, B. 1964 (Fa 486), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid and full text (click on "Additional File" below) for Folklife Archives Project 486. Folklore material classified by genre. Information collected by Sandra Kaye Loveall related to folklore genres for a folk studies class at Western Kentucky University.


Phillips, Jennifer, B. 1988 (Fa 487), Manuscripts & Folklife Archives Nov 2010

Phillips, Jennifer, B. 1988 (Fa 487), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid and full text (click on "Additional File" below) for Folklife Archives Project 487. Folklore material classified by genre. Information collected by Jennifer Phillips related to folklore genres for a folk studies class at Western Kentucky University.


Vladimir Nabokov And The Vulgar Aesthetic, Will Farina Nov 2010

Vladimir Nabokov And The Vulgar Aesthetic, Will Farina

Outstanding Honors Theses

No abstract provided.


Mccomas, Eric Donald, B. 1983 (Fa 484), Manuscripts & Folklife Archives Nov 2010

Mccomas, Eric Donald, B. 1983 (Fa 484), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid and full-text (click on "Additional File" below) for Folklife Archives Project 484. Folkore material classified by genre. Information collected by Eric Donald McComas related to folklore genres for a folk studies class at Western Kentucky University.


The Monster In The Closet: Misperception Of Mental Illness, Sarah Alexandra Bernstein Nov 2010

The Monster In The Closet: Misperception Of Mental Illness, Sarah Alexandra Bernstein

Outstanding Honors Theses

Mental illness affects all major aspects of an individual‟s life. From basic needs such as shelter and employment, to interactions with family, partners, and friends, the diagnosis represents likely difficulties due to stigma and negative attitudes. Efforts to bring forth the recognition and acceptance of mental illness in the United States, as well as around the world, start by confronting misconceptions through examination of causes. Increased access to needed resources and funding for treatment are also needed and may be accomplished through the use of media, education, and rising voices lobbying for the rights of people with mental illness.


Get M.A.D.D.: America's Battle To Overcome Drunk Driving, Elizabeth Martinez Nov 2010

Get M.A.D.D.: America's Battle To Overcome Drunk Driving, Elizabeth Martinez

Outstanding Honors Theses

No abstract provided.


Geiger, Alison Anne (Fa 14), Manuscripts & Folklife Archives Nov 2010

Geiger, Alison Anne (Fa 14), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid only for Folklife Archives Project 14. Interviews conducted by Alison Geiger with Grace (Meador) Galloway about her quilting. Includes step-by-step instructions, with photographs, demonstrating the construction of a cathedral window quilt block. Grace's life is also discussed, including raising her family on a farm in Warren County.


Women Of African Descent: Persistence In Completing A Doctorate, Vannetta L. Bailey-Iddrisu Nov 2010

Women Of African Descent: Persistence In Completing A Doctorate, Vannetta L. Bailey-Iddrisu

FIU Electronic Theses and Dissertations

This study examines the educational persistence of women of African descent (WOAD) in pursuit of a doctorate degree at universities in the southeastern United States. WOAD are women of African ancestry born outside the African continent. These women are heirs to an inner dogged determination and spirit to survive despite all odds (Pulliam, 2003, p. 337).This study used Ellis’s (1997) Three Stages for Graduate Student Development as the conceptual framework to examine the persistent strategies used by these women to persist to the completion of their studies.


Klimowicz, Teresa D. (Fa 13), Manuscripts & Folklife Archives Nov 2010

Klimowicz, Teresa D. (Fa 13), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid only for Folklife Archives Project 13. Interviews conducted by Teresa D. Klimowicz with Esther (Magers) Isbell, a native of Barren Coutny, Kentucky. Special attention is focused on her biblical themed quilts. Isbell also discusses her various occupations and participation in community affairs while living in Bowling Green, Kentucky.


Karmiller, Courtney Anne, B. 1989 (Fa 485), Manuscripts & Folklife Archives Oct 2010

Karmiller, Courtney Anne, B. 1989 (Fa 485), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid and full text (click on "Additional File" below) for Folklife Archives Project 485. Folklore material classified by genre. Information collected by Courtney Anne Karmiller related to folklore genres for a folk studies class at Western Kentucky University.


Kinchlow, Gina Lloyce (Fa 12), Manuscripts & Folklife Archives Oct 2010

Kinchlow, Gina Lloyce (Fa 12), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid only for Folklife Archives Project 12. Interviews conducted by Gina Lloyce Kinchlow with three Kinchlow family members concerning African American, middle class family life and Easter customs in New Albany, Floyd County, Indiana during the 1960s and 1970s.


Glynn, Luanne Carol (Aylesworth), B. 1951 (Fa 11), Manuscripts & Folklife Archives Oct 2010

Glynn, Luanne Carol (Aylesworth), B. 1951 (Fa 11), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid only for Folklife Archives Project 11. Interviews conducted by Luanne Carol (Aylesworth) Glynn with Marvel (Welborn) Mohon, Lewisburg, Kentucky concerning Thanksgiving customs, with much attention paid to Marvel’s life, especially her family.


Beeler, Andrew J., Jr. (Sc 2362), Manuscripts & Folklife Archives Oct 2010

Beeler, Andrew J., Jr. (Sc 2362), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Mansucripts Small Collection 2362. "Elizabeth Madox Roberts: Her Interpretation of LIfe" by Andrew J. Beeler, Jr., a thesis submitted in partial fulfillment of the requirements for the Master of Arts degree, University of Louisiville, Louisville, Kentucky, 1940.


Remember Me When I Am Gone - Exhibition (Fa 530), Manuscripts & Folklife Archives Oct 2010

Remember Me When I Am Gone - Exhibition (Fa 530), Manuscripts & Folklife Archives

FA Finding Aids

Finding aid only for Folklife Archives Project 530. Materials related to the quilt exhibition, "Remember Me When I Gone," held at the Kentucky Museum, Western Kentucky University in 1995. Includes interviews with quiltmakers about their friendship and memory quilts.


Bere, Jenny Rose, D. 1987 (Sc 2371), Manuscripts & Folklife Archives Oct 2010

Bere, Jenny Rose, D. 1987 (Sc 2371), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Manuscripts Small Collection 2371. "Cale Young Rice[:] A Study of His Life and Work" by Jenny Rose Bere, "a dissertation submitted in partial fulfillment of the requirements for the degree of Master of Arts," University of Louisville, Louisville, Kentucky, 1939.


Reaves, Gary R. (Sc 2389), Manuscripts & Folklife Archives Oct 2010

Reaves, Gary R. (Sc 2389), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Manuscripts Small Collection 2389. "The Significance of Time in the Novels of Robert Penn Warren," a thesis presented "in partial fulfillment of the requirements for the Master of Arts degree," Sam Houston State University, Huntsville, Texas, 1963.


Chaney, Thomas Peyton (Sc 2395), Manuscripts & Folklife Archives Oct 2010

Chaney, Thomas Peyton (Sc 2395), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Manuscripts Small Collection 2395. "An Analysis of the Poetry of Robert Penn Warren for Oral Interpretation," a thesis presented "in partial fulfillment of the requirements [for the] degree of Master of Arts," Baylor University, Waco, Texas, 1966.


Understanding The Uncapped Poker Florida Legislation Of 2010 And Its Affect On Florida Poker Players, The State Of Florida, And The Game Of Poker Itself., Andrew Phillips Oct 2010

Understanding The Uncapped Poker Florida Legislation Of 2010 And Its Affect On Florida Poker Players, The State Of Florida, And The Game Of Poker Itself., Andrew Phillips

Outstanding Honors Theses

No abstract provided.