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Psychology Faculty Publications

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Therapeutic Considerations Related To Finasteride Administration In Male Androgenic Alopecia And Benign Prostatic Hyperplasia, Ion G. Motofei, David L. Rowland, Daniela L. Baconi, Simona R. Georgescu, Stana Paunica, Vlad D. Constantin, Denisa Balalau, Ioana Paunica, Cristian Balalau, Catalin Baston, Ioanel Sinescu Jan 2017

Therapeutic Considerations Related To Finasteride Administration In Male Androgenic Alopecia And Benign Prostatic Hyperplasia, Ion G. Motofei, David L. Rowland, Daniela L. Baconi, Simona R. Georgescu, Stana Paunica, Vlad D. Constantin, Denisa Balalau, Ioana Paunica, Cristian Balalau, Catalin Baston, Ioanel Sinescu

Psychology Faculty Publications

Finasteride has been used extensively until now as a relative efficient therapeutic option for male androgenic alopecia and benign prostatic hyperplasia. Unfortunately, over time several concerns appeared regarding the frequency and magnitude of adverse effects, which in some cases have been even irreversible. Herein we review the recent literature on this topic, trying to clarify the current safety profile of Finasteride for these two therapeutic indications. We concluded that Finasteride could be retained as a therapeutic approach for male androgenic alopecia, based on two important reasons. First, a synergistic action between a partial inhibitor of 5α-reductase (Finasteride) and another compound …


Are Hand Preference And Sexual Orientation Possible Predicting Factors For Finasteride Adverse Effects In Male Androgenic Alopecia?, Ion G. Motofei, David L. Rowland, Simona Georgescu, Mircea Tampa, Bogdan C. Baleanu, Stana Paunica Jul 2016

Are Hand Preference And Sexual Orientation Possible Predicting Factors For Finasteride Adverse Effects In Male Androgenic Alopecia?, Ion G. Motofei, David L. Rowland, Simona Georgescu, Mircea Tampa, Bogdan C. Baleanu, Stana Paunica

Psychology Faculty Publications

Sexual side effects of finasteride seem to be redoubtable, being encountered not only during therapy but also after treatment cessation. Consequently, any possible clinical/paraclinical elements that might predict these adverse effects would be useful in the selection of a therapeutic strategy for male androgenic alopecia. Previous published studies show that some compounds that interfere with sexual hormones can decrease sexual activation and response, according to hand preference (as reported for finasteride and tamoxifen) and according to sexual orientation (as noted for bicalutamide). Our preliminary published data and the arguments presented here suggest that these two individual parameters might be used …