Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 6 of 6

Full-Text Articles in Entire DC Network

A Scoping Review Of Health Outcomes Examined In Randomized Controlled Trials Using Guided Imagery, Peter R. Giacobbi Jr., Jonathan Stewart, Keeley Chaffee, Anna-Marie Jaeschke, Meagan Stabler, George A. Kelley Dec 2017

A Scoping Review Of Health Outcomes Examined In Randomized Controlled Trials Using Guided Imagery, Peter R. Giacobbi Jr., Jonathan Stewart, Keeley Chaffee, Anna-Marie Jaeschke, Meagan Stabler, George A. Kelley

Clinical and Translational Science Institute

Introduction—Guided imagery involves the controlled visualization of detailed mental images. This integrative health technique is used for healing, health maintenance, or the treatment of specific conditions. Guided imagery is an integral part of mindfulness meditation, hypnosis, and various relaxation exercises. However, evidence to support the widespread use and dissemination of guided imagery interventions has been lacking. The purposes of this scoping review were to document the scope of health outcomes and disease processes examined by guided imagery researchers and the journal outlets where this work has been published. Secondary purposes were to review the efficacy of guided imagery, risk of …


Gingival Perfusion And Tissue Biomarkers During Early Healing Of Postextraction Regenerative Procedures: A Prospective Case Series, Lamees Alssum, Timothy D. Eubank, Sashwati Roy, Barbaros S. Erdal, Vedat O. Yildiz, Dimitris N. Tatakis, Binnaz Leblebicioglu Nov 2017

Gingival Perfusion And Tissue Biomarkers During Early Healing Of Postextraction Regenerative Procedures: A Prospective Case Series, Lamees Alssum, Timothy D. Eubank, Sashwati Roy, Barbaros S. Erdal, Vedat O. Yildiz, Dimitris N. Tatakis, Binnaz Leblebicioglu

Clinical and Translational Science Institute

Background—Post-extraction alveolar bone loss, mostly affecting the buccal plate, occurs despite regenerative procedures. To better understand possible determinants, this prospective case series assessed gingival blood perfusion and tissue molecular responses in relation to postextraction regenerative outcomes. Methods—Adults scheduled to receive bone grafting in maxillary, non-molar, single tooth extraction site were recruited. Clinical documentation included probing pocket depth (PD), keratinized tissue width (KT), tissue biotype (TB), plaque (P) and bleeding. Wound closure was clinically evaluated. Gingival blood perfusion was measured by Laser Doppler Flowmetry (LDF). Wound fluid (WF) and gingival biopsies were analyzed for protein levels and gene expression, respectively, of …


An Electronic Health Record Data-Driven Model For Identifying Older Adults At Risk Of Unintentional Falls, Adam Baus, Jeffrey Coben, Keith Zullig, Cecil Pollard, Charles Mullett, Henry Taylor, Jill Cochran, Traci Jarrett, Dustin Long Oct 2017

An Electronic Health Record Data-Driven Model For Identifying Older Adults At Risk Of Unintentional Falls, Adam Baus, Jeffrey Coben, Keith Zullig, Cecil Pollard, Charles Mullett, Henry Taylor, Jill Cochran, Traci Jarrett, Dustin Long

Clinical and Translational Science Institute

Screening for risk of unintentional falls remains low in the primary care setting because of the time constraints of brief office visits. National studies suggest that physicians caring for older adults provide recommended fall risk screening only 30 to 37 percent of the time. Given prior success in developing methods for repurposing electronic health record data for the identification of fall risk, this study involves building a model in which electronic health record data could be applied for use in clinical decision support to bolster screening by proactively identifying patients for whom screening would be beneficial and targeting efforts specifically …


Dental Workforce Availability And Dental Services Utilization In Appalachia: A Geospatial Analysis, Xue Feng, Usha Sambamoorthi, R. Constance Wiener Apr 2017

Dental Workforce Availability And Dental Services Utilization In Appalachia: A Geospatial Analysis, Xue Feng, Usha Sambamoorthi, R. Constance Wiener

Clinical and Translational Science Institute

Objectives—There is considerable variation in dental services utilization across Appalachian counties, and a plausible explanation is that individuals in some geographical areas do not utilize dental care due to dental workforce shortage. We conducted an ecological study on dental workforce availability and dental services utilization in Appalachia. Methods—We derived county-level (n = 364) data on demographic, socio-economic characteristics and dental services utilization in Appalachia from the 2010 Behavioral Risk Factor Surveillance System (BRFSS) using person-level data. We obtained county-level dental workforce availability and physician-to-population ratio estimates from Area Health Resource File, and linked them to the county-level BRFSS data. The …


Direct And Indirect Cost Of Managing Alzheimer's Disease And Related Dementias In The United States, Arijita Deb, James Douglas Thornton, Usha Sambamoorthi, Kim Innes Apr 2017

Direct And Indirect Cost Of Managing Alzheimer's Disease And Related Dementias In The United States, Arijita Deb, James Douglas Thornton, Usha Sambamoorthi, Kim Innes

Clinical and Translational Science Institute

Introduction—Care of individuals with Alzheimer’s Disease and Related Dementias (ADRD) poses special challenges. As the disease progresses, individuals with ADRD require increasing levels of medical care, caregiver support, and long-term care which can lead to substantial economic burden. Areas covered—In this expert review, we synthesized findings from studies of costs of ADRD in the United States that were published between January 2006 and February 2017, highlighted major sources of variation in costs, identified knowledge gaps and briefly outlined directions for future research and implications for policy and program planning. Expert commentary—A consistent finding of all studies comparing individuals with and …


Imaging Thiol Redox Status In Murine Tumors In Vivo With Rapid-Scan Electron Paramagnetic Resonance, Boris Epel, Subramanian V. Sundramoorthy, Martyna Krzykawska-Serda, Matthew C. Maggio, Mark Tseytlin, Gareth R. Eaton, Sandra S. Eaton, Gerald M. Rosen, Joseph P. Y. Kao, Howard J. Halpern Mar 2017

Imaging Thiol Redox Status In Murine Tumors In Vivo With Rapid-Scan Electron Paramagnetic Resonance, Boris Epel, Subramanian V. Sundramoorthy, Martyna Krzykawska-Serda, Matthew C. Maggio, Mark Tseytlin, Gareth R. Eaton, Sandra S. Eaton, Gerald M. Rosen, Joseph P. Y. Kao, Howard J. Halpern

Clinical and Translational Science Institute

Thiol redox status is an important physiologic parameter that affects the success or failure of cancer treatment. Rapid scan electron paramagnetic resonance (RS EPR) is a novel technique that has shown higher signal-to-noise ratio than conventional continuous-wave EPR in in vitro studies. Here we used RS EPR to acquire rapid three-dimensional images of the thiol redox status of tumors and normal tissues in living mice. This work presents, for the first time, in vivo RS EPR images of the kinetics of the reaction of 2H,15N-substituted disulfide-linked dinitroxide (PxSSPx) spin probe with intracellular glutathione. The cleavage rate is proportional to the …