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Medicine and Health Sciences

2017

TÜBİTAK

Mesenchymal stem cells

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Ultrastructure Of Rat Umbilical Cord Stroma-Derived Mesenchymal Stem Cells, Ahmet Ceylan, Özge Özgenç, Korhan Altunbaş, Petek Korkusuz, Asuman Özen Jan 2017

Ultrastructure Of Rat Umbilical Cord Stroma-Derived Mesenchymal Stem Cells, Ahmet Ceylan, Özge Özgenç, Korhan Altunbaş, Petek Korkusuz, Asuman Özen

Turkish Journal of Veterinary & Animal Sciences

Being multipotent progenitor cells, mesenchymal stem cells continue to attract attention as a promising tool for cell-based therapy and tissue engineering. However, research on the ultrastructure of these cells is rather scarce. This study was aimed at the investigation of the transmission electron microscopic ultrastructure and morphology of mesenchymal stem cells isolated from the stroma of rat umbilical cord using the explant culture method. At the end of the third passage, some of the cells isolated from the stroma of the umbilical cord were harvested for electron microscopic examination. The remaining cells were induced for osteogenic, chondrogenic, and adipogenic differentiation. …