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An Evaluation Of Neuroplasticity And Behavior After Deep Brain Stimulation Of The Nucleus Accumbens In An Animal Model Of Depression., Steven M Falowski, Ashwini Sharan, Beverly A S Reyes, Carl Sikkema, Patricia Szot, Elisabeth J Van Bockstaele

Department of Neurosurgery Faculty Papers

BACKGROUND: Recent interest has demonstrated the nucleus accumbens (NAcc) as a potential target for the treatment of depression with deep brain stimulation (DBS).

OBJECTIVE: To demonstrate that DBS of the NAcc is an effective treatment modality for depression and that chemical and structural changes associated with these behavioral changes are markers of neuroplasticity.

METHODS: A deep brain stimulator was placed in the NAcc of male Wistar-Kyoto rats. Groups were divided into sham (no stimulation), intermittent (3 h/d for 2 weeks), or continuous (constant stimulation for 2 weeks). Exploratory and anxietylike behaviors were evaluated with the open-field test before and after …

Personality Disorder And The Recurrent Swallowing Of Foreign Bodies, Robert Jay Claire, M.D.

Jefferson Journal of Psychiatry

Psychiatrists are frequently asked to assist colleagues with the medical and surgical sequela of psychiatric disorders. The Consultation and Liaison Psychiatry service was consulted by the Surgical Service to evaluate a patient who repeatedly swallowed foreign bodies. The following is a case report, brief review of the literature and discussion.

Use Of The Anterolateral Thigh In Cranio-Orbitofacial Reconstruction., William J Parkes, Howard Krein, Ryan Heffelfinger, Joseph Curry

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Objective. To detail the clinical outcomes of a series of patients having undergone free flap reconstruction of the orbit and periorbita and highlight the anterolateral thigh (ALT) as a workhorse for addressing defects in this region. Methods. A review of 47 patients who underwent free flap reconstruction for orbital or periorbital defects between September 2006 and May 2011 was performed. Data reviewed included demographics, defect characteristics, free flap used, additional reconstructive techniques employed, length of stay, complications, and follow-up. The ALT subset of the case series was the focus of the data reviewed for this paper. Selected cases were described …

Occupational Chemical Exposures And Psychiatric Disorders, Mark L. Dembert, M.D., M.P.H.

Jefferson Journal of Psychiatry

Occupational exposure to metals, solvents, or pesticides can produce disorders of behavior, thought, or mood which can easily be misdiagnosed as 'Junctional." Accurate diagnosis obtained with a relevant clinical history, psychiatric interview, physical examination, and indicated laboratory tests will enable the delivery of necessary medical treatment and concurrently prevent repeat exposure to a hazardous work environment. Published references and organizational sources in occupational medicine and industrial hygiene can beutilized by psychiatrists for determination of the dijferential diagnosis and confirmation of an occupational exposure; in addition, these references can aid in assessing the need for an environmental health hazard survey at …

Abca12-Mediated Lipid Transport And Snap29-Dependent Trafficking Of Lamellar Granules Are Crucial For Epidermal Morphogenesis In A Zebrafish Model Of Ichthyosis., Qiaoli Li, Michael Frank, Masashi Akiyama, Shiu-Ying Ho, Hiroshi Shimizu, Christine Thisse, Bernard Thisse, Eli Sprecher, Jouni Uitto

Department of Dermatology and Cutaneous Biology Faculty Papers

Zebrafish (Danio rerio) can serve as a model system to study heritable skin diseases. The skin is rapidly developed during the first 5-6 days of embryonic growth, accompanied by expression of skin-specific genes. Transmission electron microscopy (TEM) of wild-type zebrafish at day 5 reveals a two-cell-layer epidermis separated from the underlying collagenous stroma by a basement membrane with fully developed hemidesmosomes. Scanning electron microscopy (SEM) reveals an ordered surface contour of keratinocytes with discrete microridges. To gain insight into epidermal morphogenesis, we have employed morpholino-mediated knockdown of the abca12 and snap29 genes, which are crucial for secretion of lipids and …

Nurses Alumni Association Bulletin, Fall 2011, Susan Albrecht Curcio, Diane Warder Carugno, Sarah Hindson Wagner, Jane Ryan Dietrich, Aileen Ishuin Macmillan

Nursing Alumni Bulletins

2011 - 2012 Meeting Date Calendar

Cover 2012 Annual Luncheon & Meeting Notice

Officers, Committee Chairs, Satellite and Volunteers

Bulletin Publication Committee

The President's Message

Treasurer's Report

Resume of Minutes

Office News

Committee Reports

• Social
• Scholarship
• Relief Trust Fund
• Nominating
• Satellite - Harrisburg Satellite Area
• Bulletin
• By Laws

Annual Giving

Janet C. Hindson Award

Janet C. Hindson Award Criteria

Janet C. Hindson Award Recipient and Nominees

Memories

Era Ending (Part Two)

Mary Schaal, EdD, RN

Medical Clinic

Psychology and Nursing

Happy Birthday -To Be 80 or More

50th Anniversary Class Lists for 1961

Luncheon Attendees

Center Page

1962 - Anniversary …

65-Year-Old Man With Weight Loss, Anorexia, And Distal Extremity Numbness, Leigh Van Vranken, Ms Iii, William Kim, Ms Iii, Darren N. Seril, Md, Toshimasa Okabe, Md

The Medicine Forum

Case Report

A 65-year-old Caucasian male with no significant pastmedical history presented to the emergency department with an unintentional 44-pound weight loss over a four-month period. The weight loss was preceded by fatigue and anorexia,which had been increasing for approximately eight months.In addition, he noted numbness and tingling of his hands and feet that began over the same time period. The patient was initially treated for depression with sertraline by his primarycare physician. However, his symptoms persisted without significant improvement. An initial workup at outside hospital one month prior to presentation included an abdominal CTscan, which revealed a mass in …

A 30 Year-Old Man Infectious Endocarditis And Cerebrovascular Accident, Neerav G. Sheth, Md, Joseph Desimone, Md

The Medicine Forum

Case Report

A 30 year old male with a remote history of intravenous drugabuse (IVDA) and Hepatitis C was admitted in July 2008 with changes in mental status and a new right sided paresis. According to the family, the patient was in his usual state of health until approximately 2-3 weeks prior to admission when he developed headaches, generalized malaise, and fever to 101 degrees Fahrenheit after swimming in a lake. He was seen in an outside hospital emergency department, diagnosed with otitis media and subsequently discharged on prednisoneand ciprofloxacin. The morning of admission, the patient was found naked, nonverbal, …

Download Entire Issue-The Jefferson Medicine Forum, Volume 6, Winter 2004

The Medicine Forum

Download entire issue-The Jefferson Medicine Forum, Volume 6, Winter 2004.

What's Your Diagnosis? Hematology Slide Review, Jane Choi Md, Pgy-2

The Medicine Forum

A 23 year-old Caucasian female with no past medical

history presents with one week of easy bruising and

increasing “red spots” on her arms and chest. She does

not recall any history of trauma that may have lead to

the bruises. She denies any fever or chills. She has no

history of bleeding problems and underwent dental

procedures last year without any complications. On

review of systems, she had vague left abdominal pain over

the past week and 3 days of right ear pain that was

recently treated with cefuroxamine as directed by her

primary care doctor. Family history is …

Exposure Risks And The Chain Of Healthcare-Associated Infection, Amber Hogan Mitchell, Drph, Mph, Cph

Building the Chain of Safety: Stakeholders Summit

Amber Hogan Mitchell, DrPH(c), MPH, CPH is the Worldwide Director of Professional Education and Learning Solutions for Advanced Sterilization Products (ASP), a Johnson & Johnson Company located in Irvine, CA. Amber is responsible for educational initiatives for ASP and its customers related to infection prevention, healthcare associated infections, sterilization, disinfection, environmental hygiene, and quality initiatives in healthcare related to safe care and quality patient outcomes. Amber is a Doctor of Public Health Candidate (all but dissertation) in occupational and environmental health sciences at the University of Texas School of Public Health in Houston, TX. She was a Centers for Disease …

Urological Involvement In Renal Transplantation., Daniel D Sackett, Pooja Singh, Costas D Lallas

Department of Urology Faculty Papers

Historically, urologists were the primary surgeons in renal transplantation. Specialization and increased complexity of the field of transplantation, coupled with a de-emphasis of vascular surgical training in urology, has created a situation where many renal transplants are carried out by surgeons with a general surgery background. Because of its genitourinary nature, however, urological input in renal transplantation is still vital. For living donors, a urologist should be involved to help evaluate and prepare certain patients for eventual donation. This could involve both medical and surgical intervention. Additionally, urologists who carry out living donor nephrectomy maintain a sense of ownership in …

The Pulmonologist's Role In Caring For Pregnant Women With Regard To The Reproductive Risks Of Diagnostic Radiological Studies Or Radiation Therapy., Robert Brent

Department of Pediatrics Faculty Papers

Radiography of the chest, head, neck, teeth, or extremity exposes the embryo or ovary to insignificant exposures of radiation except when radionuclides are utilized. In some instances, there is no exposure at all. Pulmonologists are fortunate with regard to the specific studies they request to provide clinical care because most of the diagnostic tests do not directly expose the uterus (embryo) or ovary. This article discusses radiation risks and their evaluation and pregnancy-related issues in diagnostic radiological studies.

Innovatively Changing Us Health Care From The Perspecitve Of A Japanese Physician, Akira Babazono Ms, Md, Phd

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Hpn Winter 2011 Download Full Pdf

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Global To Local: Apic Chapters Build Community Awareness For Iipw In Their Communities, Janiene Torch Bohannon, Mary Lou Manning, Louise Hesse, Patrice Fitzsimons, Linda Huddleston, Colleen Chapple, Leanne Mikielski, Diana Doughty, Ossama Rassian, Maha Fathy, Lamia Fouad, Mostafa Abdel Nasser

College of Nursing Faculty Papers & Presentations

No abstract provided.