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An Observation On Direct Changes In Aedes Albopictus Midgut Cells By Rhus Tox 6c In Relation To Dengue Virus Infection, Moonmoon Sinha, Enakshi Roy, Satadal Das, Debabrata Sarkar, Debadatta Nayak, Anil Khurana, Raj Manchanda
An Observation On Direct Changes In Aedes Albopictus Midgut Cells By Rhus Tox 6c In Relation To Dengue Virus Infection, Moonmoon Sinha, Enakshi Roy, Satadal Das, Debabrata Sarkar, Debadatta Nayak, Anil Khurana, Raj Manchanda
Indian Journal of Research in Homoeopathy
Background and Objectives: In mosquito vectors, dengue virus (DENV) invasion occurs through midgut cells, but available mosquito cell lines for in vitro study of DENV are prepared from eggs or larvae, which are not appropriate models, to study its infectivity. Hence, we developed a new primary cell culture, from Aedes albopictus mosquito midgut, and standardized it for in vitro study of DENV, with an aim to find out any possible role of homoeopathic medicines, in preventing or reducing DENV invasiveness in these midgut cells. This midgut primary cell culture demonstrated prominent cytopathic effects on infection with wild DENV isolated from …