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Calf Diarrhea (Scours): Reproduced With A Virus From A Field Outbreak, C. A. Mebus, N. R. Underdahl, M. B. Rhodes, M. J. Twiehaus
Calf Diarrhea (Scours): Reproduced With A Virus From A Field Outbreak, C. A. Mebus, N. R. Underdahl, M. B. Rhodes, M. J. Twiehaus
Historical Research Bulletins of the Nebraska Agricultural Experiment Station
Neonatal calf diarrhea typical of that seen in field cases was produced in colostrum-deprived calves by inoculating either feces or bacteria-free filtrates via the duodenum, orally, or by a spray (aerosol). Three calves, kept free of E. coli, developed severe diarrhea following inoculation with a bacteria-free filtrate. Intense fluorescence in the epithelium of sections of small intestine from two experimental calves was observed following staining with ftuorescein-labeled gamma globulin produced with viral antigen prepared from the feces of two experimental diarrhetic E. coli-free calves. Fluorescing cells were also present in the feces of experimental and field cases of neonatal …