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Balancing Root-Zone Oxygenation And Rhizosphere Stability: The Impact Of Aeration And Hypoxia On Hydroponic Plant Growth, Christian D. Baker

All Graduate Theses and Dissertations, Fall 2023 to Present

As the global population and food demand continue to increase, growers must look to innovative and sustainable methods for plant cultivation. Hydroponics is a popular method of sustainable plant cultivation where plant roots are suspended over a liquid nutrient solution. Hydroponics uses less water compared to traditional agriculture because there is no evaporation or solution runoff. It also maximizes land use, requires fewer pesticides and herbicides, and enables year-round cultivation in controlled environments. However, indoor hydroponic systems rely on artificial lighting, which has higher energy costs than traditional farming methods. Optimizing growing conditions is therefore critical to ensure long-term economic …

The Benefits And Barriers To Expanding Crna Programs In Michigan, Grace Van Zweden

Honors Theses

The demand for Certified Registered Nurse Anesthetists (CRNAs) and their delivery of safe, high-quality anesthesia care has increased significantly due to nationwide anesthesia provider shortages and the growing reliance on CRNAs to meet healthcare system needs. This demand underscores the importance of expanding nurse anesthesia programs in Michigan and across the United States to support nurses pursuing advanced education and to improve patient access to essential care within their communities. The CRNA profession has evolved over time to meet the changing needs of the healthcare system, and current CRNA programs require applicants to satisfy rigorous and highly specific admission criteria. …

Compact 1 Ghz Electron Paramagnetic Resonance Spectrometers For Preclinical Imaging Studies, Tanden A. Hovey

Electronic Theses and Dissertations

Magnetic resonance is one of the most generally useful scientific techniques. New horizons of understanding are revealed as technological advances make possible explorations of nuclear spins and electron spins at higher and lower magnetic fields and electromagnetic frequencies. While the greatest current effort is on ever higher magnetic fields and microwave frequencies, both in nuclear magnetic resonance (NMR) and electron paramagnetic resonance (EPR), the Eaton lab focusses on developing high signal-to-noise performance EPR at low microwave frequencies. EPR provides information about O2, pH, viscosity, glutathione concentrations, and reactive oxygen species in living organisms that MRI cannot. To yield clinically or …

The Experience Of Sleep And Academic Performance Among African American College Students: A Case Study, Jamean Alma Alexander

Walden Dissertations and Doctoral Studies

The transition to college presents significant challenges for African American college students, particularly in developing effective study habits and maintaining healthy sleep behaviors that support academic success. Despite growing evidence linking sleep and academic performance, limited research has explored how African American students attending historically Black colleges and universities (HBCUs) perceive these experiences. The purpose of this qualitative case study was to explore the perceptions and experiences of African American college students regarding sleep habits, study habits, and academic performance. Guided by three research questions, data were collected through semi structured interviews with 12 African American students attending HBCUs in …

Ppt-1 Regulates Lipid Droplet Homeostasis And Promotes Oxidative-Stress Resilience In C. Elegans., Chukwuadinula Deborah Ashiedu

Master’s Theses and Projects

No abstract provided.

Evaluating The Discus Throw As An Ancient Greek Combat Training Tool Through Modern Performance Metrics, Daniel R. Porter

All Graduate Reports and Creative Projects, Fall 2023 to Present

This study’s purpose was to explore the correlations between peak velocity in a rotational throw with a medicine ball, peak force (PF) and rate of force development (RFD) in an isometric mid-thigh pull, time to failure in a plank test, and peak velocity in a sword thrust task, which was also tested for reliability. Twenty-seven recreationally trained male participants between the ages of 18-35 completed the study. The sword thrust task was significantly correlated with the medicine ball throw (p = 0.012, r = 0.475, r² = 0.226, 95% CI [0.724, 0.116]) and PF (p = 0.045, r …

Bridging Animal Production And Human Nutrition: How Production Ecology Shapes The Nutritional Quality Of Terrestrial Animal Foods And Human Omega-3 Status, Joseph Vinod Varre

All Graduate Theses and Dissertations, Fall 2023 to Present

The question at the center of this dissertation is simple: does the way food is produced change the quality of the food itself in ways that matter for human health? Across a series of studies on bison meat, eggs, and human dietary intervention, the answer was yes. This work began with a broad look at the modern food system and the nutritional consequences of industrialized diets. In particular, it focused on the growing imbalance between omega-6 and omega-3 fatty acids in the Western diet. This balance matters because omega-3 fats support heart, brain, and immune health, and diets high in …

Behavioral And Dietary Associations Of Vitamin D Deficiency Among Landscaping Workers: An Analytical Cross-Sectional Study In El Paso, Texas., Cristela Anahi Avila

Open Access Theses & Dissertations

Background: Vitamin D deficiency is a persistent public health concern, even among outdoor workers who receive substantial sunlight exposure. Landscaping workers may still be at risk because sun-protective clothing, early work hours, behavioral practices, and low dietary intake can reduce effective vitamin D synthesis. Purpose: This pilot study examined dietary vitamin D intake, sun exposure behaviors, and serum 25-hydroxyvitamin D status among male landscaping workers in El Paso, Texas, to identify behavioral and nutritional factors associated with deficiency. Methods: Twenty participants completed a culturally adapted food frequency questionnaire and behavioral assessment and underwent capillary point-of-care testing for serum 25(OH)D. Descriptive …

Spatial Heterogeneity And Temporal Trends Of California Extreme Heat Using High-Resolution Earth System Model Simulations, Eleni Konstantelos

Master's Theses

Extreme heat threatens California’s diverse landscapes and populations through intensifying and geographically shifting patterns. This study examined the temporal trend and spatial heterogeneities of California’s extreme heat for 1994–2015. The analysis was based on the fully coupled Energy Exascale Earth System Model version 2 (E3SMv2), specifically its 25-km regionally refined configuration. While the Desert/Inland region exhibited the highest number of days ≥ 35 °C and the highest heatwave severity, Central Valley showed the fastest increase in the number of days ≥ 35 °C and heatwave events, as well as the fastest increases of days exceeding various heat index thresholds over …

Interpretable Wellness Prediction From Passive Wearable Sensor Data Using Large Language Models, Cheng-Huan Yu

Master's Theses

This thesis presents a unified framework for multi-target wellness prediction using passive wearable sensor data and large language models (LLMs). The study integrates two complementary paradigms: prompt-based regression and representation-driven classification. In the first stage, structured wearable representations derived from daily physiological signals are used to prompt LLMs to predict stress, fatigue, sleep quality, and readiness. Two input representations are evaluated: statistical summaries and hybrid inputs combining statistical summaries with raw sensor values. To improve interpretability and prediction consistency, the second stage introduces a representation-centric classification framework in which wearable signals and wellness targets are discretized into categorical levels. Multiple …

Essays In Applied Microeconomics, Md Tahmeed Hossain

Economics Theses and Dissertations

This dissertation contributes to empirical economics research by examining three settings in which historical shocks, behavioral constraints, and localized public events affect social relations, decision quality, and public safety. The first chapter examines the persistence of historical religious conflict in contemporary Hindu–Muslim relations in India. The second chapter studies how time pressure affects decision quality in online chess. The third chapter analyzes the localized traffic-safety externalities of NFL game days. Across these settings, the dissertation uses large-scale data and quasi-experimental research designs to distinguish causal effects from selection, spatial concentration, and persistent local conditions.

The first chapter asks whether historical …

Integrative Assessment Of Body Composition And Micronutrient Status In An Adult Egyptian Population, Roua Aref Nouh

Theses and Dissertations

Integrative Assessment of Body Composition and Micronutrient Status in an Adult Egyptian Population: A Functional and Biochemical Approach

Obesity and metabolic dysfunction are increasingly recognized as heterogeneous conditions that cannot be sufficiently characterized by body mass index (BMI) alone. Alterations in body composition, particularly central adiposity and skeletal muscle mass, may coexist with micronutrient imbalances even among individuals who fall outside conventional BMI-based obesity classifications. In clinical settings, such metabolic vulnerability is frequently accompanied by non-specific functional symptoms, highlighting the need for integrative assessment approaches that extend beyond weight-centered metrics. This cross-sectional study aimed to investigate the associations between micronutrient …

A Computational Micropatterning Approach To Study Caveolae And Protein Localization In Vascular Biology, Andrew B. Grespin

Electronic Theses and Dissertations

Caveolae are specialized, flask-shaped membrane invaginations highly expressed in endothelium and dysregulated in atherosclerosis. Caveolae play a central role in buffering membrane tension, yet the principles governing their spatial organization remain elusive. Thus, we sought to generate the most comprehensive and systematic analysis of blood vessel caveolar spatial organization. However, cell culturing, the backbone of human-focused biological research, does not standardly do well to model physiologically relevant cell behaviors such as migration or polarity-based tissue formation, particularly for punctate proteins and structures like caveolae. Micropatterns are cell-adhesive shapes that biophysically confine cell(s) to a user defined geometry which stereotype organelle …

An Integrated Sensor-Fusion Framework For Performance-Based Compensation In Construction, Aly Ayman El-Ashry

Theses and Dissertations

Construction productivity has historically stagnated due to a reliance on subjective labor monitoring and “lagging” performance indicators. This research proposes a novel compensation model with the use of Total Energy Management System (TEMS) to translate labor effort and efficiency into payment incentives with the integration of Internet of Things (IoT) wearables and Statistical Process Control (SPC) charts.

This research addresses the systemic problem of declining construction productivity caused by industry’s inability to objectively quantify human effort. While traditional models rely on post-facto production tallies, a significant research gap exists in real-time physiological labor monitoring. To bridge this, the proposed TEMS …

Middle Management Diplomacy: An Examination Of Us Foreign Policy Analysis In Middle-Echelon Diplomatic Professionals, Isaac R. Silvino

Master's Theses

This study analyzes the role which managerial level U.S. military Foreign Area Officers and Foreign Service Officers play in shaping and implementing U.S. foreign policy. By analyzing the individual professional at the middle-echelons of an organizational hierarchy, we make an effort in dispelling ourselves from obscured perceptions of IR centered on character and state idealization driven narratives. Doing this may help bridge the foundational gap between academics and practitioners while shifting towards a paradigm of IR analysis focusing on human agency and decisions.

Result

Individual managerial echelon diplomats do not directly make policy, but rather play a crucial role in …

Slouching Towards Inefficiency? The Cardiometabolic And Cognitive Costs Of Poor Posture, Ava Mae Fitzenrider

Honors Projects

Posture affects all of our lives. It is both static and dynamic, adapting continuously to environmental demands. One postural alteration frequently observed in occupational settings is hyperkyphosis, which can be induced by sitting position. During computer use, individuals commonly adopt a slouched posture, which can exacerbate hyperkyphosis, and contribute to dis-ease within the body. Previous research has demonstrated that such postural deviations can negatively affect pulmonary function, as well as other bodily functions. Despite these findings, the effects of acute hyperkyphosis (“slouching”) on cardiometabolic function and cognition remain largely unexplored. Therefore, the purpose of this study was to examine the …

The Effect Of Acute Hypoxia Exposure, With Exercise, On Bone Metabolic Biomarkers, Alyssa Bailly

Health, Exercise, and Sports Sciences ETDs

Hypoxic environments, resulting from decreased atmospheric partial pressure of oxygen, reduce oxygen availability in the blood and tissues, leading to a mismatch between supply and demand. This elicits several physiological adaptations and may influence bone metabolism. Although evidence suggests that hypoxia can modulate bone remodeling through hypoxia-inducible pathways, findings remain mixed, with most data derived from chronic hypoxic exposures in animal and cell culture models. Exercise, an essential stimulus for bone health, may exacerbate hypoxic stress; however, the skeletal response to acute hypoxic exposure combined with exercise remains unclear. We propose that intermittent exercise in hypoxia may increase negative markers …

Microtubules In Breast Cancer: Exploring The Α/Β-Tubulin Toggle Switch And Its Implications In Human Breast Cancer, Annemarie Ianos

Student Theses and Dissertations

Microtubules, composed of a/b-tubulin heterodimers, play a central role in breast cancer tumor growth by polymerizing, leading to metastasis and depolymerizing, contributing to proliferation. Human enzymes protein kinase Ca (PKC-a) and cyclin-dependent kinase 1 (Cdk-1) mediate phosphorylation at sites a:Ser165 and b:Ser172, respectively, influencing the growth of microtubules. It is possible that alternating phosphorylation at these sites contribute to an a/b-tubulin “toggle switch” that mediates microtubule instability and tumor growth.

The project investigates the influence of the toggle switch model on microtubule stability by determining the impact of mutants (a:S165D, a:S165N, a:S165S_P, b:S172S_P and a:S165S_P/b:S172S …

Data-Driven Approaches To Investigate Cardiotoxicity Using Hipscs High Throughput Screening, Danny Vu

Theses - ALL

Recent advances in human induced pluripotent stem cell (hiPSC) technology have enabled the development of high-throughput platforms for cardiotoxicity screening. However, conventional analytical approaches remain limited by time-intensive processing, manual annotation requirements, and reduced scalability for large datasets. To address these challenges, calcium fluorescence signals from human induced pluripotent stem cell-derived cardiomyocytes (hiPSC CMs) were analyzed using a high-throughput imaging platform and complementary machine learning frameworks. First, a feature-based supervised learning approach using engineered waveform descriptors and low-dimensional signal embeddings enabled rapid and interpretable screening of large chemical datasets, with combined features improving predictive performance relative to engineered features alone. …

Illuminating Success: Student And Teacher Perception On Media Center Brainlit Lighting, Jase M. H. Ide

Undergraduate Honors Thesis Collection

Lighting plays a critical role in shaping learning environments, yet its influence on students’ cognitive, emotional, and physiological functioning is often overlooked in educational research. This study examined the perceived impact of BrainLit’s biocentric lighting, a daylight-simulating system designed to support circadian rhythms, within an educational setting. The research focused on Sycamore School, the first early childhood through eighth-grade school in the United States to implement BrainLit biocentric lighting. Using a qualitative research design, data were collected through interviews with third- and eighth-grade students and faculty members in the school’s Media Center. Transcribed interviews were analyzed thematically to identify patterns …

Impostor Thoughts At Work: Examining The Relationship Between Impostor Thoughts, Employee Well-Being, And Coworker Support, Nikitha Sara Mohan

Theses, Dissertations and Culminating Projects

Most individuals experience impostor thoughts; however, limited construct clarity has hindered efforts to effectively examine their relationship with employee outcomes (Gullifor et al., 2021). To address this limitation, the present study adopts a sociocognitive perspective, conceptualizing impostor thoughts as beliefs that others overestimate one’s competence at work (Clance & Imes, 1978; Tewfik, 2022). Specifically, this research investigates workplace impostor thoughts and their associations with indicators of employee well-being, including job-related negative affect, burnout, physical symptoms, and perceived self-competence. Additionally, the study examines coworker support as a potential moderating factor in these relationships. A mixed-methods approach was employed. Quantitative data were …

The Physical, Chemical, And Emotional Discourse Of Hormonal Disruption By Microplastics And Nanoplastics, Lily Warken

Theses & ETDs

Microplastics (MPs)1 and nanoplastics (NPs) are emerging as a growing concern within the health field as plastic use continues to rise. These particles have been increasingly recognized for their potential to act as endocrine-disrupting chemicals (EDCs), interfering with normal hormonal signaling and receptor function. This study examines the molecular, hormonal, and reproductive impacts of MPs and NPs on the human body, with particular attention to the importance of endocrine homeostasis and its sensitivity to disruption. In some cases, MPs and NPs and their adsorbed contaminants may mimic endogenous hormones and interact with hormone receptors, further complicating regulatory processes. Special emphasis …

The Impact Of Glucose Exposure On Organic Cation Transporters (Oct) Function In A Corneal Epithelial Cell Line, David A. Garza

Theses & Dissertations

Organic cation transporters (OCT) facilitate the movement of neurochemicals and medications, contribute to the removal of cellular waste, and facilitate neuronal communication. Three subtypes of these high-capacity, low-affinity transporters (OCT1, OCT2, and OCT3) are differently expressed in peripheral tissues such as the liver, kidneys, as well as the central nervous system. OCTs are also expressed in ocular tissues. Chronic hyperglycemia is a complication commonly associated with diabetes that can lead to ocular diseases such as diabetic keratopathy, which affects the cornea. In this project, we expose immortalized human corneal epithelial cells (HCE-S) to various glucose concentrations to study their impact …

Design And Development Of A Perfusable Hydrogel Platform With Bioprinted Human-Endothelialized Microvascular Channels, Calvin A. Chernyatinskiy

All Theses

We developed an integrated bioprinting and perfusion platform to generate vascularized hydrogel constructs that support perfusable microchannel networks. Multiple hydrogel formulations, sacrificial ink systems, device geometries, and perfusion conditions were systematically evaluated to optimize print fidelity, mechanical stability, and cellular compatibility. Internally gelling alginate–calcium carbonate hydrogels were identified as a robust matrix, providing tunable gelation kinetics and structural stability during embedded printing. In parallel, Pluronic F-127 fugitive ink enabled reliable fabrication of continuous hollow channels due to its shear-thinning behavior and efficient post-print removal.

The finalized platform integrates stereolithographically fabricated perfusion chambers with extrusion-based bioprinting to produce three-dimensional, perfusable vascular …

Effects Of Tourist Feeding On The Gut Microbiome And Ecophysiology Of Endangered Northern Bahamian Rock Iguana (Cyclura Cychlura), Erin Lucy Lewis

All Graduate Theses and Dissertations, Fall 2023 to Present

The lifespan and reproduction of an animal depends on maintaining a healthy physiology. The proportion of individuals that survive to an age at which procreation can occur is important to long-term stability of populations and contributes to species survival. Health in an animal is measured in a variety of ways, including through monitoring of the body’s physiological systems, as well as its ability to respond to invading pathogens, and through the different types of bacteria present in the gut. Relationships among those different health metrics have been discovered in recent years and have been found to play important roles in …

Characterizing Metabolic Flux Of Plant Secondary Metabolites From Diverse Animal-Source Foods To Humans, Muhammad Ahsin

All Graduate Theses and Dissertations, Fall 2023 to Present

There is a popular saying: “You are what you eat.” But does this also mean, “You are what your food eats”? This dissertation explores that question by examining how farming practices shape the nutritional quality of meat—and what, if anything, those differences mean for the people who consume it. While modern livestock production and nutrition research often emphasize protein and fat, this work tests the idea that animals function as biological mediators, linking soil and plant conditions to human diets through the chemical composition of meat and milk. To evaluate this hypothesis, we tracked health-relevant plant compounds— phytonutrients—across the soil–plant–animal–human …

Urban Illumination And Circadian Disruption: Examining Artificial Light At Night, Caitlin Mcmasters

Theses

Artificial light at night is increasingly prevalent in dense urban environments, yet it remains unclear how often typical city lighting conditions likely exceed recommended nighttime limits for residential circadian health. This thesis evaluates nighttime light exposure in two contrasting urban districts, Back Bay in Boston and Times Square in New York City, using satellite derived nighttime radiance, GIS based urban morphology, and documented lighting infrastructure characteristics. Rather than relying on calibrated photometric simulations, the study employs a qualitative, evidence based comparative approach to assess relative façade exposure and interpret conditions against established benchmarks, including the WELL Building Standard and ILP …

A Treatise On Tool Development: The Arthroscope’S Cultural, Technological, And Metascientific Translation, Montgomery F. Waterer

Honors Theses

The arthroscope was a revolutionary development in the fields of medicine, engineering, and ethics. There are many valuable lessons to be learned from the story of its development and translation that are relevant to the future of medicine and society. Beginning with a brief description of the tool’s design, this paper will examine a period within the history of the arthroscope. This window contains multiple innovators and ends with the life and work of Dr. Robert Jackson. In examining the relevant historical facts of its development, this paper will then briefly address the importance of sports medicine in the development …

Piloting A Scalable Workflow To Identify Drivers Of Mammalian Aging Using C. Elegans, Ariella Lucia Coler-Reilly Colasanti

Arts & Sciences Graduate Student Theses and Dissertations

The aging population in developed countries has prompted experts to warn of the impending “silver tsunami” of older adults poised to overload already strained healthcare systems. Advanced age is the primary risk factor for most chronic diseases, and the vast majority of the elderly population is diagnosed with at least one such condition, if not several. The field of geroscience has emerged to study the processes responsible for age-related decline and devise methods to reduce this burden. A major branch of geroscience is the genetics of aging, including examining gene expression changes over time as well as exploring how genetic …

Dietary Manipulations Of The Undernourished Infant Microbiome, Cyrus Zhou

Arts & Sciences Graduate Student Theses and Dissertations

Today, undernutrition affects approximately 150 million children worldwide. During the first two years of life, the healthy gut microbial community undergoes a series of predictable developmental transitions. These transitions are delayed in undernourished children resulting in microbiota “immaturity.” In a foundational study, immature gut microbial communities from undernourished children and normally developing communities from chronologically age-matched healthy children living in the same area were transplanted into groups of germ-free mice consuming the same diet – one representative of what consumed by the study population. Compared mice with a mature gut microbiome, mice with an immature gut microbiome had impaired weight …