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Impact Of The Emergency Use Authorization On Ventilator Innovation, Krista Stanislow

Theses

Innovation in the medical device industry is crucial to continuously improve the health and wellbeing of society. The U.S. Food and Drug Administration (FDA) is responsible for ensuring the safety and effectiveness of medical devices on the market while balancing the need for continuous innovation. One way the FDA has tried to support innovation is through the development of the 510(k) pathway, which does not require clinical testing as the safety of the device is determined based on a predicate device. Many companies choose to develop products that can obtain approval through the 510(k) pathway. While the 510(k) pathway is …

Protecting Health Data In A Pandemic: A Systematic Adversarial Threat Analysis Of Contact Tracing Apps, Leah Krehling

Electronic Thesis and Dissertation Repository

In this thesis centralized, decentralized, Bluetooth, and GPS based applications of digital contact tracing were reviewed and assessed. Using privacy principles created by a contingent of security and privacy experts from across Canada, a metric of assessing an application’s privacy was created. An attack tree was built to assess the security of the contact tracing applications. Eighteen attacks were theorized against contact tracing applications currently in use. An application’s vulnerability to the attacks was measured using a scoring system developed for this purpose. The results of the security scores were used to create a metric for assessing the security of …

Posttraumatic Growth During Covid-19: A Quantitative Analysis Of Individualist And Collectivist Values, Stephanie Chalk

Dissertations, 2020-current

The 2019 Coronavirus Disease (COVID-19) pandemic has spurred a major global crisis. Collective trauma is inevitable. Compared to posttraumatic stress, relatively little research has been conducted on posttraumatic growth. This study examined the associations between individualism-collectivism, coping behaviors, and posttraumatic growth in the context of COVID-19. A total of 314 adult participants were recruited to complete a questionnaire on COVID-19 experiences, individualism-collectivism, coping, and posttraumatic growth. Posttraumatic growth was measured globally and across five factors: relating to others, personal strength, new possibilities, appreciation of life, and spirituality. A t-test found no difference in global posttraumatic growth in participants who were …

Pandemic Driven Innovation: Development Of An Alternative Respiratory Pathogen Self-Collection Device, Thang Nguyen

Theses & Dissertations

The SARS-CoV-2 virus outbreak has underscored numerous weak links in our biodefense countermeasures against highly communicable diseases. Many believe it was our lack of an effective testing model that allowed the virus to become a global pandemic within a short period. The gold standard collection method for the SARS-CoV-2 virus involves mechanical debridement of the nasopharyngeal cavity with a stiff swab applicator, which has been known to cause pain and injury to patients, subsequently resulting in low patient acceptance of the procedure. Due to the invasive nature of the nasopharyngeal swab collection method, it may not be conducive to the …

Multi-Level Small Area Estimation Based On Calibrated Hierarchical Likelihood Approach Through Bias Correction With Applications To Covid-19 Data, Nirosha Rathnayake

Theses & Dissertations

Small area estimation (SAE) has been widely used in a variety of applications to draw estimates in geographic domains represented as a metropolitan area, district, county, or state. The direct estimation methods provide accurate estimates when the sample size of study participants within each area unit is sufficiently large, but it might not always be realistic to have large sample sizes of study participants when considering small geographical regions. Meanwhile, high dimensional socio-ecological data exist at the community level, providing an opportunity for model-based estimation by incorporating rich auxiliary information at the individual and area levels. Thus, it is critical …

An Interdisciplinary Analysis Of Health Equity As Evaluated Through The Covid-19 Response Concerning French-Speaking Refugees., Margaret Henning

Honors Theses

A collaborative approach is needed to understand the multifaceted medical bias and inequalities experienced by refugee camps of Francophone (French-speaking) nations. A combination of interest and passion for anthropology, medicine, and the French language presents a unique window of intersectionality to analyze this issue. Through a comprehensive review of literature published in both English and French languages, and connections with directors and leaders of refugee camps located in France and French-speaking African nations, we have elucidated a few examples of alarming medical bias experienced by both refugees and migrants. Although an exhaustive list of medical bias could be presented on …

Women Who Dared: Female Entrepreneurs Defy Odds To Start Businesses During Covid-19, Kinza Tahir

MSJ Capstone Projects

With leadership roles being increasingly won by women all over the world, society benefits in all aspects especially economically when women earn incomes. In the trying times of the COVID-19 pandemic, many women usually perceived as second class citizens of Pakistan have started their own ventures amidst the pandemic.

Safety Huddles: A Safety Net For Nurses Amid The Covid-19 Pandemic, Miranda Saint-Louis

DNP Qualifying Manuscripts

In March 2020, our 31-bed geriatric medical unit was designated the first COVID-19 unit in a teaching hospital located in a New York City COVID-19 hot zone. At the time, little was known about SARS-CoV-2 and the disease it caused. We needed to find a way to keep them calm, assure their safety, and provide competent and compassionate patient care in a situation where best practices had not yet been established. The concepts from this article can be applied to provide support staff in any crisis. Providing a safety net for staff enables a focus on life-saving patient care without …

Early Prison Releases And Hotel Placements Produce Unexpected Outcomes During The Pandemic, Buzz Von Ornsteiner

Capstones

The transition from prison to the harsh realities of New York City is seldom easy. Finding employment and housing is always a huge challenge but in 2020 COVID-19 has shadowed the incarcerated. As returning New Yorkers, their stories are unique. Ironically, the added obstacles they face have also brought them benefits in the form of the housing they need to survive during a deadly pandemic.

Early Prison Releases And Hotel Placements Produce Unexpected Outcomes During The Pandemic, Buzz Von Ornsteiner

Capstones

The transition from prison to the harsh realities of New York City is seldom easy. Finding employment and housing is always a huge challenge but in 2020 COVID-19 has shadowed the incarcerated. As returning New Yorkers, their stories are unique. Ironically, the added obstacles they face have also brought them benefits in the form of the housing they need to survive during a deadly pandemic.

Crisis Within A Crisis: A Comparative Analysis Of Covid-19’S Implications On Greece And Spain’S Migrant And Refugee Processing Policies, Injy Elhabrouk

Undergraduate Honors Theses

With the onset of the COVID-19 pandemic came a collective global panic regarding health, safety, and security. Since the major outbreak of the coronavirus in March of 2020, few issues have received scrutiny and attention in the public sphere. Yet, the problems that existed before COVID-19 have not become obsolete, however, they were removed from the public eye. One such issue to receive less scrutiny is the treatment of the most vulnerable populations in the world—migrants and refugees. Spain and Greece’s locations on the Mediterranean Sea mean they are often the first place migrants seek refuge in their journey to …

A Systems Approach To Increase The Icu Nursing Workforce During A Pandemic, Jennifer Mendenhall

Master's Projects and Capstones

A Systems Approach to Increase the ICU Nursing Workforce During a Pandemic

Abstract

In early March 2020 an intensive care unit (ICU) patient died of COVID-19 in an integrated healthcare system hospital in Northern California. Data from China and the CDC indicated that more healthcare members would require intensive care and could overwhelm the 21 acute care hospital macrosystem. A microsystem pilot program to upskill peri-anesthesia care unit (PACU) RNs to care for ICU patients was initiated. Concurrently the upskill pilot program was reviewed by macrosystem nursing leadership. Over a three-week period, the program was standardized, disseminated and implemented across …

Maintaining Team Vitality In The Asu Pacu During The Covid-19 Crisis, Melissa Eagleton

Master's Projects and Capstones

Abstract

Problem: COVID-19 has generated issues and concerns in the healthcare field for staff and clinical settings worldwide, especially for this ambulatory surgery unit post-anesthesia care unit (ASU PACU). Although there was no measurable quality gap, there was a concern for a decrease in patient safety, employee satisfaction, and burnout because the staff were required to become critical care nurses to provide care for the critically ill COVID-19 patients.

Context: The ASU PACU was a critical part of the surge plan if the hospital could no longer house the influx of COVID-19 patients. The unit was shut down entirely two …

Creating A Thriving Informatics Culture, Nicholas Webb

Doctor of Nursing Practice (DNP) Projects

Nurses thrive best when they are empowered to make decisions that can positively impact healthcare delivery. Knowledge and application of nursing informatics principles can influence clinical, quality, operational, and financial outcomes in ways that were not available in previous professional nursing generations.

If nursing informatics is the solution, what is the problem? A survey regarding use and attitudes about nursing informatics was taken of chief nurse executives (CNEs) at an integrated, not for profit healthcare system in the Northern California region, where the author oversees the electronic health record (EHR). The results were surprising. Half said they did not know …

A Case Study: School Professionals’ Perspectives On Students Exiting Middle School Entering An Achievement High School, Joy Davis Lee

USF Tampa Graduate Theses and Dissertations

Each year approximately 1.3 million students dropout of high school and an estimated 40% of minority students do not graduate on time (Roybal, Thornton, & Usinger, 2014). In high school, 22% of students repeat 9th-grade classes because students fail to make a smooth transition. This gives the 9th-grade the highest enrollment rate and the highest dropout rate (McCallumore & Sparapani, 2010). In an effort to increase high school graduation rates, the Peabody County Public School District created Achievement schools, an initiative to recruit highly effective administrators, teachers and staff members to support students with the highest academic and nonacademic needs. …

Online Interpretation Guideline For Historic House Museums, Olivia A. Weixlmann

Museum Studies Theses

What does it mean to be a museum in 2020? How do cultural institutions, charged with preserving our history, navigate the challenges of the modern world? Technological advances including the internet, quickly produce an abundance of media outlets baiting attention that impact the sociopolitical climate driving civil unrest, and ideological division. The surplus of competing information from technology driven outlets result in audiences being overwhelmed and left questioning if the information they're receiving is from a reliable source.

Worst Time Being Poor? The Hunger Problem In U.S. During Covid-19 Pandemic, Yuanhang Hu

School of Professional Studies

Food insecurity is deeply rooted in American society during and before the COVID-19 pandemic. Food Insecurity usually associates with economic indicators, such as unemployment rate, income level, etc. Currently, there are two main tools to fight the war of hunger. The first one is the government food assistance programs. And the second one is food pantries from the private sectors of the community. Both tools are facing numerous challenges due to COVID-19. The purpose of this article is to provide rational reasons to persuade the government to enhance the benefits of the Supplemental Nutrition Assistance Program (SNAP) and use administrative …

Cvs Covid-19 Screening Website: Test Automation, Savya Rawat

School of Professional Studies

CVS Pharmacy is an American retail corporation, also known as, and originally named, the Consumer Value Store owned by CVS Health, it is headquartered in Woonsocket, Rhode Island. CVS Pharmacy is currently the largest pharmacy chain in the United States by number of locations over 9,600 and total prescription revenue. CVS sells prescription drugs and a wide assortment of general merchandise, including over-the-counter drugs.

Now, coming to the reason why I have selected CVS pharmacy’s website cvs.com as my case study topic is because of CVS’s response to the covid-19 pandemic’s no-cost testing strategy. Whole of the world is suffering …

Higher Education Responses To Crisis: A Case Study Of Clark University And The Pandemic Of 2020, Lisa Gillingham

School of Professional Studies

The COVID-19 pandemic has delivered an existential challenge to universities and other academic institutions at a time when they are already grappling with other weighty issues that may alter the fabric of higher education. COVID-19 has forced these institutions to consider and employ new ways of conducting its work with a sense urgency that is unprecedented in the recent history of the academy. The rate of learning around these models is rapid, and Higher Education is ripe for change.

Clark University has addressed the pandemic with a plan to protect and pivot using strategies that support the continuation of its …

Estimating Covid-19 Survival Rate And Inferring Case Severity With Respect To Milwaukee County Policy Change Using Logistic Regression, Geoff M. Chappelle

Theses and Dissertations

Coronavirus disease 2019 (COVID-19) is a global issue, and it is affecting 170 countries in very different ways. In the United States, a lot of efforts have been made nationally and by individual states to curb the spread and severity of COVID-19. Policy changes and recommendations have been met with variable success across the country. There is a wealth of information on where COVID-19 infection and death are prevalent, and there are several articles discussing disparities in those outcomes among different populations. However, those findings are not necessarily tied to a policy change or, in the weeks that follow a …

Privacy In Multigenerational Homes Before And Amidst Covid-19, Jennifer Luque

Electronic Theses and Dissertations

Multigenerational households in the United States are more prevalent now than they have been in the last forty years. In part, aging, illness, job loss, saving money, and even tradition are factors that contribute to the idea of multiple generations living together in one home. Given the health of the individuals, size of the home, and number of dedicated bedrooms and bathrooms, living multigenerational can have both positive and adverse effects. Many family groups fall into the category of multigenerational living. However, this study investigates the relationships between adults and senior family members in terms of privacy in the home. …

Inhibitors Of The Sars-Cov-2 Papain-Like Protease, Zachary P. Del Mundo

Honors Capstones

The papain-like protease (PLpro) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a target enzyme for treatment of the 2019 coronavirus infectious disease (COVID-19). Multiple lead competitive inhibitors to the protease have been previously discovered, particularly VIR250, HGN1034, and GYX402. Analogs of these ligands were designed using ChemSketch or Chem3D. The ligand-active site interactions of those unique ligands were observed and compared using AutoDock Tools, which also computes a predicted inhibitory constant (K​i)​ . Over the Fall 2020 semester, proficiency in performing several functions of AutoDock Tools was acquired, and a total of thirteen unique and original compounds …

Mcst : An App For Patron Awareness Of Covid-19 Safety Measures Instituted By Small Businesses, Jorge Torres

Theses, Dissertations and Culminating Projects

Small businesses across America are having restrictions placed upon them due to the COVID-19 pandemic. Those fortunate enough to remain open now face the challenge of trying to generate enough revenue to stay afloat. Small businesses, with their lack of funds, have resorted to listing their safety precautions on their front door to inform patrons. However, viewing these rules would require patrons to leave their homes. Additionally, there is no consistent set of rules being enforced by the government which is dangerous as some patrons may feel that stricter procedures be in place. These inconsistencies and lack of information can …

Great Expectations: Phosph(On)Ate Prodrugs In Drug Design—Opportunities And Limitations, Victoria Yan

Dissertations & Theses (Open Access)

Phosphate and phosphonates are chemical moieties with historical precedence in anticancer and antiviral nucleotide analogues. Synchronous to modern efforts identifying novel therapeutic targets in cancer, such chemical moieties are being investigated in the design of novel inhibitors with antineoplastic potential. A central challenge to the delivery of phosph(on)ate-containing drugs is their anionic character at physiological pH, which portends poor membrane permeability. This limitation has been successfully overcome through the use of prodrugs. When attached to the phosph(on)ate moiety, prodrugs mask the negative charge and easily enable cell permeability. Upon cellular entry, the promoieties are enzymatically or environmentally cleaved to unveil …

Dancing Through Covid: An Ethnographic Exploration Of Exotic Dancers' Experiences During A Pandemic, Danyelle Sturdivant

Anthropology Undergraduate Senior Theses

The novel coronavirus pandemic, quarantine, and social distancing measures affected working conditions for a variety of workers. Exotic dancers were distinctly impacted due to the stigma of their work which, prior to the pandemic, often involved the sale of close-proximity lap dances. This paper explores exotic dancers’ experiences during the COVID-19 pandemic to provide insight on the unique challenges they faced.

Data were gleaned using ethnographic methods with modifications informed by phenomenology. Existentially-engaged participant observation was performed in a small, Southern strip club, identified here as Flare. Two rounds of formal, recorded interviews were conducted with six exotic dancers, and …

Inviting Entry-Level Composition Students To Interact With Their Instructor Outside Of The Classroom: Influences, Trends, And New Perspectives, Alyssa K. Knight

MSU Graduate Theses

This study enters the discourse surrounding student-faculty interaction through an investigation of out-of-class interactions within an entry-level composition course. Empirical studies have found students and instructors in undergraduate courses often communicate infrequently, but most studies gathered quantitative data on interactions through student reporting. This study investigated influences on undergraduate students’ desire to interact with the course instructor outside of the classroom through the lens of both the instructor and the students. This study addressed the potential differences between students’ perceptions and the course instructor’s observations and found that the instructors’ demeanor, course content, and instructional delivery impact the number of …

Evaluating A Graduated Exposure Treatment To Teach Mask Tolerance Among Children With Autism, Hallie Marie Ertel

Theses and Dissertations

Due to the COVID-19 outbreak, the Center for Disease Control (CDC) recommends that everyone 2 years and older wear a mask while out in a community setting (CDC, 2020a). It is important for children to learn how to tolerate wearing a mask for long durations of time while out in the community. In the current study, which was comprised of 2 experiments, we implemented a graduated exposure procedure to teach mask wearing to 6 children diagnosed with Autism Spectrum Disorder (ASD). The purpose of experiment 1 was to evaluate the efficacy of a graduated exposure procedure to teach mask tolerance …

Developing A Community Innovation Grant In Response To Increasing Rural Critical Incidents In Agricultural Mental Health And Wellbeing, Community Trauma, And Natural Disasters, Chessa S. Quenzer

Capstone Experience

Spink Area Support Network (SASN) is a skilled team of community volunteers that facilitate rural critical incident response services in an effort to prevent a critical incident and offer structured support during the aftermath. SASN was developed in response to identified gaps in rural critical incident response and risk reduction through prevention in Spink County, South Dakota. SASN utilizes a collaborative team approach to fill in gaps between first responder silos and establish community interventions by providing support and resources while utilizing critical incident stress management methods. SASN requires funding to maintain response resources, training, prevention education, and follow-up services. …

Assessing Occupational Stress And Preparedness Among Campus Safety Officers And Dental School Employees At An Academic Medical Center During Covid-19, Decature Banker, Lorena Baccaglini, Miriam Mccann, Chandran Achutan

Capstone Experience

Job stress can lead to adverse physical and emotional health effects in employees and is worse during an emergency or pandemic. The complexity of the coronavirus disease 2019 (COVID-19) pandemic is taking a toll on the healthcare systems and their employees. This cross-sectional study looked at two different groups of academic medical center employees, Campus Safety Officers and Dental School employees, who’s work puts them at risk for COVID-19 exposure. We hypothesized that Campus Safety Officers and Dental School employees who felt adequately trained to conduct COVID-19 related work would not feel more stressed during the COVID-19 pandemic than they …

Chemical Modification And In Silico Validation Of Medicinally Privileged Molecular Scaffolds As Kras And Sars-Cov-2 Protease Inhibitors, Precious M. Okwuchukwu

Theses and Dissertations

Coronavirus disease was declared a global pandemic by WHO in March 2020, cancer is the second leading cause of death by a disease. Several scientists around the world are working relentlessly to discover an effective remedy to eradicate these deadly diseases. A natural polyphenol (magnolol) has been isolated from a tree Magnolia grandiflora (family Magnoliaceae) found on UTRGV campuses. This research is focused on design of a series of chemically modified sulfonyl derivatives based on the isolated magnolol framework and other medicinally privileged molecular scaffolds framework that can effectively bind to the COVID-19 main protease, SARS- CoV-2 3CL protease …