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Stprompt++: Prompting Vision-Language Models For Weakly Supervised Video Anomaly Detection And Fine-Grained Localization, Peng Wu, Chengyu Pan, Guansong Pang, Xiangteng He, Zhiwei Yang, Peng Wang, Yanning Zhang Jul 2028

Stprompt++: Prompting Vision-Language Models For Weakly Supervised Video Anomaly Detection And Fine-Grained Localization, Peng Wu, Chengyu Pan, Guansong Pang, Xiangteng He, Zhiwei Yang, Peng Wang, Yanning Zhang

Research Collection School Of Computing and Information Systems

Traditional weakly supervised video anomaly detection (WSVAD) tasks typically rely on coarse-grained frame-level labels for training. Although this approach reduces annotation costs, it results in weak semantic understanding and spatial localization capabilities due to the absence of fine-grained annotations, hindering precise pixel-level anomaly detection and localization. Thanks to the success of vision-language models (VLMs), e.g., CLIP, recent approaches leveraging large VLMs focus on exploiting their strong semantic understanding capabilities, but they typically feed only keyframes or short video segments into the models, without supplying sufficient prior contextual information (e.g., contextual frames around anomalies, zoomed-in anomaly regions, and detailed anomaly descriptions), …

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Uncovering The Story Of Sally Maria Johnson: Revealing The History Of The Portrait Of A Painting, Yuanzhen Song Sep 2027

Uncovering The Story Of Sally Maria Johnson: Revealing The History Of The Portrait Of A Painting, Yuanzhen Song

Art Conservation Master's Projects

Portrait of Sally Maria Johnson by the artist James Johnson is a 19th century oval shaped portrait in the collection of the Buffalo History Museum.  It suffered from structural damages and paint loss resulting from surface alterations and previous restoration campaigns.  This study combines art historical research with scientific analysis to explore both the biography of the subject and the materiality of the painting.  Through local research including historical newspaper articles in Buffalo, the story of Sally Maria Johnson (the wife of Buffalo’s first mayor) was uncovered.  High-resolution imaging techniques were used to document the surface condition and identify …

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Avian Influenza And The Approach To Designing An H5n1 Vaccine, Lauren N. Hickey May 2027

Avian Influenza And The Approach To Designing An H5n1 Vaccine, Lauren N. Hickey

Honors Program: Senior Projects (Public)

The Avian influenza virus (AIV) H5N1 has been responsible for the culling and deaths of millions of birds since 2022 with concern for wildlife, livestock, and human infections occurring as well. With eggs flying off the shelves in grocery stores, even individuals not involved in the agricultural industry have seen the drastic effects of this disease first-hand. For chickens, this virus works quickly and overpowers the innate immune system before the adaptive immune system has time to properly respond. Therefore, a safe and effective vaccine could reduce the number of poultry deaths and prevent the continuous spread of the infection. …

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Bridging The Gap Between Career Expectations Versus Labor Market Realities, Reinette P. Madrid, Grethel T. Ledesma, Ignatius Aryono Putranto, Jyro B. Triviño Jan 2027

Bridging The Gap Between Career Expectations Versus Labor Market Realities, Reinette P. Madrid, Grethel T. Ledesma, Ignatius Aryono Putranto, Jyro B. Triviño

Leadership and Strategy Faculty Publications

Most students lack awareness regarding the labor market outcomes for their chosen college majors. This study aims to answer what factors affect the career expectations of graduating students at Quezon City University and how these expectations align with the prevailing labor market situation. It employed descriptive, causal, and explanatory research using a sample of 108 respondents from fourth-year information technology students for the school year 2021 to 2022. Eight of the nine null hypotheses were rejected by employing multinomial logistic and linear regression. Student fixed effects and other labor market outcomes significantly predicted salary, estimated stability, and estimated skills in …

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Fragmented Data Privacy Statutes And Political Insecurity In The Face Of Dormant Commerce Clause Challenges, Filip Malesev Jan 2027

Fragmented Data Privacy Statutes And Political Insecurity In The Face Of Dormant Commerce Clause Challenges, Filip Malesev

Student Works

No abstract provided.

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Bodily Autonomy And Involuntary Servitude: Applying The Thirteenth Amendment To Restrictions On Abortion In The Case Of Pregnancy Induced By Rape, Joseph Innocente Jan 2027

Bodily Autonomy And Involuntary Servitude: Applying The Thirteenth Amendment To Restrictions On Abortion In The Case Of Pregnancy Induced By Rape, Joseph Innocente

Student Works

No abstract provided.

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The Seven Noahide Laws, Mendy Schapiro Jan 2027

The Seven Noahide Laws, Mendy Schapiro

Student Works

No abstract provided.

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Optimizing Human Fcrn Mouse Models To Improve Pharmacokinetic Evaluation Of Antibody Drug Candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, Elena Gonzalo-Gil Dec 2026

Optimizing Human Fcrn Mouse Models To Improve Pharmacokinetic Evaluation Of Antibody Drug Candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, Elena Gonzalo-Gil

Faculty Research 2026

The use of animal models that can reliably predict drug performance in human patients is critical to antibody therapeutic development. Along with assessing toxicity and efficacy, determining the pharmacokinetic (PK) properties of therapeutics in Tg32 and Tg276 mice is essential to preclinical characterization. While Tg32 mice have been well established as indispensable in their ability to model the PK properties of antibody therapeutics, their intact immunity leaves them capable of mounting anti-drug antibody responses that interfere with PK interpretation. Here, we demonstrate the negative impact anti-drug responses can have on PK parameters derived from Tg32 mice, and provide strong evidence …

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Optimizing Human Fcrn Mouse Models To Improve Pharmacokinetic Evaluation Of Antibody Drug Candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, Elena Gonzalo-Gil Dec 2026

Optimizing Human Fcrn Mouse Models To Improve Pharmacokinetic Evaluation Of Antibody Drug Candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, Elena Gonzalo-Gil

Faculty Research 2026

The use of animal models that can reliably predict drug performance in human patients is critical to antibody therapeutic development. Along with assessing toxicity and efficacy, determining the pharmacokinetic (PK) properties of therapeutics in Tg32 and Tg276 mice is essential to preclinical characterization. While Tg32 mice have been well established as indispensable in their ability to model the PK properties of antibody therapeutics, their intact immunity leaves them capable of mounting anti-drug antibody responses that interfere with PK interpretation. Here, we demonstrate the negative impact anti-drug responses can have on PK parameters derived from Tg32 mice, and provide strong evidence …

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Steroid Receptor Coactivator 3-Deficient Regulatory T Cells Eradicate Multiple Solid Tumors In Syngeneic Mouse Models, Nuri Sung, Eunsu Kim, Yosef Gilad, Yuri Park, Adam M Dean, Yan Xia, Jianming Xu, Clifford C Dacso, David M Lonard, Sang Jun Han Dec 2026

Steroid Receptor Coactivator 3-Deficient Regulatory T Cells Eradicate Multiple Solid Tumors In Syngeneic Mouse Models, Nuri Sung, Eunsu Kim, Yosef Gilad, Yuri Park, Adam M Dean, Yan Xia, Jianming Xu, Clifford C Dacso, David M Lonard, Sang Jun Han

Faculty, Staff and Students Publications

Steroid receptor coactivator 3 (SRC-3) is highly expressed in regulatory T cells (Tregs) and is important for their immunosuppressive activity. Recently, we demonstrated that disrupting SRC-3 expression in Tregs eliminates triple-negative breast cancer (TNBC) and prostate cancer in syngeneic animal models by generating an anti-tumor immune microenvironment without inducing immune-related adverse events (irAEs). Further analysis of these mice revealed that SRC-3 knockout (KO) Tregs infiltrated breast tumors and facilitated the infiltration of CD8

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The Hemostatic Properties Of Green Plasma, David J. Sun Dec 2026

The Hemostatic Properties Of Green Plasma, David J. Sun

Summer Research Program Abstracts

No abstract provided.

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Methods For Tagging Whale Sharks: Insights Into Performance And Best Practices With A Focus On Clamp Attachments, Freya C. Womersley, Sofia Green, Alberto Garcia-Baciero, Ronan Conlon, Amy L. Jeffries, Matt J. Waller, Sara S. Ratão, Nuno Queiroz, Pedro Afonso, Gonzalo Araujo, Adam Barnett, Christine Barry, Michael L. Berumen, Farukhkha Bloch, Ginevra Boldrocchi, Camrin D. Braun, Ryan Caillouet, Constance Chapman, Jesse E.M. Cochran Dec 2026

Methods For Tagging Whale Sharks: Insights Into Performance And Best Practices With A Focus On Clamp Attachments, Freya C. Womersley, Sofia Green, Alberto Garcia-Baciero, Ronan Conlon, Amy L. Jeffries, Matt J. Waller, Sara S. Ratão, Nuno Queiroz, Pedro Afonso, Gonzalo Araujo, Adam Barnett, Christine Barry, Michael L. Berumen, Farukhkha Bloch, Ginevra Boldrocchi, Camrin D. Braun, Ryan Caillouet, Constance Chapman, Jesse E.M. Cochran

Faculty Publications

Background: Biologging and telemetry have transformed our understanding of marine megafauna movement ecology. Yet, methodological constraints continue to limit data quality and deployment duration. Devices recording whale shark (Rhincodon typus) behaviours and movements have been used for decades, but they remain challenging to deploy and vary in success. Recently, spring-loaded clamp-based systems have emerged as one of the most widely used approaches to attach electronic tags to the fins of this globally endangered species. Currently, however, no consensus guidelines exist as to how to optimise this approach, potentially leading to continued underperforming deployments limiting analysis potential. Here, we synthesise experiences …

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Infestation By Phorid Flies Disrupts Behavior And Immune Function In Honey Bees Monitored By Radio-Frequency Identification, Gloria Ruiz-Guzmán, Oliverio Delgado-Carrillo, Francisco J. Balvino-Olvera, María De Jesús Aguilar-Aguilar, Violeta Patiño-Conde, Paulo De Souza, Ulises Olivares-Pinto, Mauricio Quesada Dec 2026

Infestation By Phorid Flies Disrupts Behavior And Immune Function In Honey Bees Monitored By Radio-Frequency Identification, Gloria Ruiz-Guzmán, Oliverio Delgado-Carrillo, Francisco J. Balvino-Olvera, María De Jesús Aguilar-Aguilar, Violeta Patiño-Conde, Paulo De Souza, Ulises Olivares-Pinto, Mauricio Quesada

Research outputs 2022 to 2026

Honey bees (Apis mellifera Linnaeus) are important pollinators in natural and agricultural ecosystems and play a key role in global food production. However, colonies are increasingly affected by multiple stressors, including emerging parasites, which can compromise their health and performance. Among these, phorid flies (Diptera: Phoridae) have been observed in association with weak or collapsing honey bee colonies in various regions in Mexico, yet their effects on honey bee behavior and immune function under field conditions remain poorly understood. In this study, we investigated the impact of a phorid fly infestation on the behavior, survival, and immune defense of A. …

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The Relationship Between Dietary Sodium Intake And Cognitive Function: A Narrative Review, Samantha L. Gardener, M. Fu, L. Morini, T. Schwartzkopff, G. Savage, R. N. Martins, S. R. Rainey-Smith Dec 2026

The Relationship Between Dietary Sodium Intake And Cognitive Function: A Narrative Review, Samantha L. Gardener, M. Fu, L. Morini, T. Schwartzkopff, G. Savage, R. N. Martins, S. R. Rainey-Smith

Research outputs 2022 to 2026

Purpose of Review: This narrative review provides discussion on current evidence regarding the relationship between sodium intake and cognitive function in animal and human studies, as well as potential mechanisms underlying this relationship. Recent Findings: Recent evidence suggests high sodium intake is associated with development of cognitive impairment and neural dysfunction. Additionally, studies have proposed that high sodium intake is associated with increased aggregation of Aβ-amyloid and that hypertension (for which high sodium intake is a risk factor) modulates the relationship between Aβ-amyloid and development of cognitive impairment and Alzheimer’s disease. However, while animal studies demonstrate a consistent relationship between …

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Sarcomerogenesis: Evidence, Context And Key Stimuli—Response To The Commentary By Power Et Al., Anthony J. Blazevich, Walter Herzog, João Pedro Nunes Dec 2026

Sarcomerogenesis: Evidence, Context And Key Stimuli—Response To The Commentary By Power Et Al., Anthony J. Blazevich, Walter Herzog, João Pedro Nunes

Research outputs 2022 to 2026

No abstract provided.

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Implementation And Effectiveness Of A Food Education Intervention To Promote Plant-Based Foods: A Partially Cluster-Randomized Controlled Trial, Henna Vepsäläinen, Satu Kinnunen, Sari Niinistö, Leena Forma, Suvi T. Itkonen, Tuuli E. Korhonen, Liisa Korkalo, Heli Kuusipalo, Jelena Meinilä, Kaija Nissinen, Susanna Raulio, Ros Sambell, Mari Åkerlund, Suvi M. Virtanen, Maijaliisa Erkkola Dec 2026

Implementation And Effectiveness Of A Food Education Intervention To Promote Plant-Based Foods: A Partially Cluster-Randomized Controlled Trial, Henna Vepsäläinen, Satu Kinnunen, Sari Niinistö, Leena Forma, Suvi T. Itkonen, Tuuli E. Korhonen, Liisa Korkalo, Heli Kuusipalo, Jelena Meinilä, Kaija Nissinen, Susanna Raulio, Ros Sambell, Mari Åkerlund, Suvi M. Virtanen, Maijaliisa Erkkola

Research outputs 2022 to 2026

Background: Legumes can substitute for meat and are thus a particularly important food group for environmental sustainability. As the use of legumes among Finnish children is marginal, there is potential for a substantial increase in their consumption. However, food education delivered through early childhood education and care (ECEC) settings has rarely focused specifically on environmentally sustainable foods, such as legumes. This study describes the implementation and effectiveness of an ECEC-delivered food education intervention within the FoodStep study. Methods: The partially cluster-randomized FoodStep intervention aimed to increase the supply of vegetables, legumes, fruits, berries, and sustainable fish while reducing the provision …

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A Critical Review Of Pharmaceutical Pollutants In Soil And Air: Ecotoxicological Impacts On Animal, Plant And Microbial Communities - Health Hazards And Waste Management, Md Faisal Amin, Md. Saydur Rahman Dec 2026

A Critical Review Of Pharmaceutical Pollutants In Soil And Air: Ecotoxicological Impacts On Animal, Plant And Microbial Communities - Health Hazards And Waste Management, Md Faisal Amin, Md. Saydur Rahman

School of Integrative Biological & Chemical Sciences Faculty Publications

Pharmaceutical contamination in soil and air has become a critical environmental concern due to its widespread sources, complex behavior, and long-lasting ecological impacts. This review comprehensively explores the presence, fate, and effects of pharmaceutical compounds in soil, highlighting their entry routes, environmental persistence, and biological consequences. Pharmaceuticals infiltrate terrestrial and aquatic environments through various pathways, including agricultural application, pharmaceutical manufacturing waste, sewage sludge, hospital and household discharges, irrigation with contaminated water, and atmospheric deposition. A wide range of drug classes, such as antibiotics, analgesics, non-steroidal anti-inflammatory drugs, antidepressants, anticancer drugs, and hormones, have been identified in both soil and air …

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Individual And Household Factors Associated With Tungiasis In A Marginalized Population In Karamoja, Northeastern Uganda, Lynne Elson, Abneel K. Matharu, Berrick Otieno, Hermann Feldmeier, Charles Waiswa, Amina Abubakar, Jürgen Krücken, Ulrike Fillinger, Francis Mutebi Dec 2026

Individual And Household Factors Associated With Tungiasis In A Marginalized Population In Karamoja, Northeastern Uganda, Lynne Elson, Abneel K. Matharu, Berrick Otieno, Hermann Feldmeier, Charles Waiswa, Amina Abubakar, Jürgen Krücken, Ulrike Fillinger, Francis Mutebi

All Peer-Reviewed Publications

Background: Tungiasis is a neglected tropical skin disease caused by adult female fleas which burrow into the skin of people and animals, causing considerable pain and itching. The distribution of the disease is heterogeneous, with Napak district, Karamoja sub-region of northeastern Uganda having the highest disease burden recorded globally. We aimed to determine the factors associated with this high prevalence to inform future intervention strategies. Methods: We conducted a cross-sectional study to identify factors associated with infection of individual children and adults, and a nested case–control study to identify factors for whole households (families). Infected children were identified through mass-screening …

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A Projector-Rank Partition Theorem For Exact Degrees Of Freedom In Experimental Design, K. G. Nagananda Dec 2026

A Projector-Rank Partition Theorem For Exact Degrees Of Freedom In Experimental Design, K. G. Nagananda

Mathematics and Statistics Faculty Publications and Presentations

In many experimental designs—split-plots, blocked or nested layouts, fractional factorials, and studies with missing or unequal replication—standard ANOVA procedures no longer tell us exactly how many independent pieces of information each effect truly contributes. We provide a general degrees of freedom (df) partition theorem that resolves this ambiguity. For N observations, we show that the total information in the data (i.e., N −1 df) can be split exactly across experimental effects and randomization strata by projecting the data onto each stratum and counting the df each effect contributes there. This yields integer df—not approximations—for any mix of fixed and random …

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Mtorc2-Nav1.2 Signaling Drives Early Hyperexcitability In Alzheimer’S Disease Mouse Model, Nolan M Dvorak, Jeffrey L Noebels Dec 2026

Mtorc2-Nav1.2 Signaling Drives Early Hyperexcitability In Alzheimer’S Disease Mouse Model, Nolan M Dvorak, Jeffrey L Noebels

Faculty, Staff and Students Publications

Hyperexcitability is a biomarker of early-stage Alzheimer’s Disease (AD) and hastens cognitive decline later in its course. Mechanistic target of rapamycin (mTOR) signaling contributes to the slope of this trajectory, as evidenced by early increased brain expression and the rescue of hyperexcitability by genetic deletion of mTOR complex 2 (mTORC2); however, a molecular mechanism directly linking mTOR signaling to membrane hyperexcitability in early-stage AD remains elusive. Here, we show that hyperactive mTOR signaling stimulates the voltage-gated Na+ channel 1.2 (Nav1.2), a previously identified downstream phosphorylation target of mTORC2 and a key regulator of membrane electrogenesis. Augmented Nav1.2 channel function induced …

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Harnessing Digital Twin (Dt) Technology For Food Security And Climate Resilience In Sub-Saharan Africa (Ssa), Henri E.Z. Tonnang, Francis Chianu, Siyabusa Mkuhlani, Francis Muthoni, John Michael Humphries Choptiany, Franck B.N. Tonle, Bonoukpoe M. Sokame, Mercy Lung’Aho Dec 2026

Harnessing Digital Twin (Dt) Technology For Food Security And Climate Resilience In Sub-Saharan Africa (Ssa), Henri E.Z. Tonnang, Francis Chianu, Siyabusa Mkuhlani, Francis Muthoni, John Michael Humphries Choptiany, Franck B.N. Tonle, Bonoukpoe M. Sokame, Mercy Lung’Aho

All Peer-Reviewed Publications

Sub-Saharan Africa (SSA) faces chronic food insecurity despite possessing approximately 60% of the world’s uncultivated arable land. Field trials generate evidence but are costly and insufficiently scaled to address accelerating climate and demographic pressures. Digital twin (DT) technology, defined as the continuous, bidirectional virtual replication of physical systems using real-time data, supports monitoring, modelling, and optimisation of agrifood systems. To our knowledge, however, no published synthesis has examined DT agriculture research through the lens of SSA food systems or smallholder farming realities. A PRISMA-compliant systematic review was conducted across bibliographic databases using a pre-defined Boolean search and adapted PICOS eligibility …

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Biomechanical Gait Analysis To Classify Neurological Gait Scores In A Spina Bifida Sheep Model, Shreya Pandiri Nov 2026

Biomechanical Gait Analysis To Classify Neurological Gait Scores In A Spina Bifida Sheep Model, Shreya Pandiri

Summer Research Program Abstracts

No abstract provided.

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The Two Fridas: How The Use Of Semiotics Reflects The Social History Of Mexico In Frida Kahlo’S Work, Raquel Maria Botteon Martins Nov 2026

The Two Fridas: How The Use Of Semiotics Reflects The Social History Of Mexico In Frida Kahlo’S Work, Raquel Maria Botteon Martins

SPARK Symposium Presentations

Frida Kahlo and Diego Rivera are often credited as having played a crucial role in establishing a Mexican avant-garde. According to the Denver Art Museum’s statement for the exhibition Frida Kahlo, Diego Rivera, and Mexican Modernism, their body of work often incorporated portrayals of mexicanidad, an identity born of Mexico’s ancient cultures and its colonial past that projected a visionary future. The use of mexicanidad imagery started with the efforts to create a new national art, following the Mexican revolution, when the country used public and socially effective art to communicate new ideals of identity.  Through the analysis of …

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Keyframe Selection From Motion Capture Data With Dual-Agent Reinforcement Learning, Kun Hu, Wang, Clinton Mo, Mingyang Ma, Shaohui Mei, Zebin Chen, Zhiyong Wang Nov 2026

Keyframe Selection From Motion Capture Data With Dual-Agent Reinforcement Learning, Kun Hu, Wang, Clinton Mo, Mingyang Ma, Shaohui Mei, Zebin Chen, Zhiyong Wang

Research outputs 2022 to 2026

Animation production workflows centered around motion capture techniques require animators to edit motions based on a set of keyframes. However, most existing keyframe selection methods are optimization-based, which suffer from the issues of flexibility and efficiency. In this paper, a novel deep reinforcement learning method with dual agents are proposed for unsupervised keyframe selection. First, an S-Agent and an R-Agent evaluate the actions of selection and refinement, respectively. A deep spatio-temporal network, namely graph keyframe evaluation network (GKEN), is proposed for the agents. Then, an animation specified reward is devised based on reconstruction, which fulfills three important properties of the …

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Effects Of Demineralization Protocols On Hydrogen And Oxygen Isotope Ratios In Fossil Bone Collagen, Linda M. Reynard Nov 2026

Effects Of Demineralization Protocols On Hydrogen And Oxygen Isotope Ratios In Fossil Bone Collagen, Linda M. Reynard

Boise State University Publications and Presentations

The effect of three commonly used preparation protocols on bone collagen δ2H and δ18O values was investigated, using six generally well-preserved faunal bones (cattle, bison, horse) ranging in age from the Holocene to Late Pleistocene. The treatments tested were ethylene diamine tetraacetic acid demineralization without gelatinization and hydrochloric acid demineralization with and without gelatinization. There are significant shifts in δ18O values among preparation methods. No systematic shifts in bone collagen δ2H values were noted among the three treatments, and most offsets were low (< 2–3 ‰) and smaller than typical measurement uncertainties. A few sample/treatment combinations yielded slightly higher inter-treatment δ2H differences (∼ 5–7 ‰). Lower mass fraction of hydrogen in …

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Conventional And Emerging Pre-Treatments For Plant Protein Fermentation: Prospects For Next-Generation Plant-Based Meat Analogues, Vishal Sharma, Ruth M. Hamill, Eduarda M. Cabral, Catherine M. Burgess, Catherine Barry-Ryan Oct 2026

Conventional And Emerging Pre-Treatments For Plant Protein Fermentation: Prospects For Next-Generation Plant-Based Meat Analogues, Vishal Sharma, Ruth M. Hamill, Eduarda M. Cabral, Catherine M. Burgess, Catherine Barry-Ryan

Research Outputs: 2025-Present

The development of plant-based meat analogues (PBMAs) that accurately replicate meat texture and flavor remains limited by fundamental structural differences between plant and animal proteins. Most notably, the globular conformation of plant proteins contrasts with the fibrous anisotropy of animal muscle, thereby limiting viscoelasticity. Additional challenges include beany off-notes arising from lipid oxidation products such as hexanal and anti-nutritional factors (ANFs) that reduce bioavailability. Fermentation is a traditional technology increasingly explored as a strategy to address these limitations by modifying protein structure and functional properties, and by promoting the formation of savory volatile compounds. However, conventional processing and extraction of …

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Fall 2026 Environmental Sciences Seminar Series, Wenjing Xu, Wenjing Xu Oct 2026

Fall 2026 Environmental Sciences Seminar Series, Wenjing Xu, Wenjing Xu

NRESS Seminars

Animal movement is fundamental to biodiversity, offering early signals of species' responses to environmental change. I first discuss how wildlife movement is shaped by landscape composition and configuration, from global to local scales. I then focus on one linear infrastructure reconfiguring landscapes worldwide: fences. Drawing on research from the western US and beyond, I show how fences reshape animal movement, with cascading consequences for ecosystems and societies. I close with reflections on broadening this science through visual storytelling.

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Activity-Dependent Astrocytic Cholesterol Release Fine-Tunes Modes Of Synaptic Exo- And Endocytosis, Jongyun Myeong, Vitaly A Klyachko Oct 2026

Activity-Dependent Astrocytic Cholesterol Release Fine-Tunes Modes Of Synaptic Exo- And Endocytosis, Jongyun Myeong, Vitaly A Klyachko

2020-Current year OA Pubs

Cholesterol is essential for the organization of neurotransmitter release machinery, yet how it regulates the balance among different forms of synaptic exo- and endocytosis remains poorly understood. Moreover, which pre-synaptic processes rely on neuronal vs. astrocyte-derived cholesterol is unknown. Using nanoscale-precision imaging of single-vesicle release in hippocampal synapses, we demonstrate that astrocytic cholesterol is a critical determinant of both temporal and spatial aspects of presynaptic dynamics by differentially modulating the two main forms of synchronous release, univesicular (UVR) and multivesicular (MVR), effectively fine-tuning their balance. Moreover, astrocytic cholesterol determines the spatial distribution of vesicle release across the active zone and …

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The Round That Never Ends: The Inverted Alms Round As Post-Labor Infrastructure — Location-Based Anonymous Micro-Donations To Opted-In Stationary Public Meditators, Triggered By Presence Rather Than Need, With Ai-Funded Forward-Only Giving Balances For Recipients, Thon Ly Oct 2026

The Round That Never Ends: The Inverted Alms Round As Post-Labor Infrastructure — Location-Based Anonymous Micro-Donations To Opted-In Stationary Public Meditators, Triggered By Presence Rather Than Need, With Ai-Funded Forward-Only Giving Balances For Recipients, Thon Ly

Defensive Publications Series

We describe a location-based voluntary giving system in which pedestrian donors give small, fixed, anonymous micro-donations to opted-in participants who sit still in public places, such as public meditators. Eligibility is triggered only by the verifiable fact of opted-in, stationary public presence, never by an assessment of need or of any inner state, and a participant's presence is surfaced to nearby donors' devices without displaying need, housing status or any ranking. The system sits above an unconditional baseline-support floor that it may never gate, replace or draw down. Above the floor it specifies three channels: the donor-to-sitter micro-donation layer, with …

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Appreciation As World-Building: A Location-Based Virtual World Rendered From A User's Signed Ledger Instead Of Purchasable Cosmetics, With Location-Verified Content Creation And Read-Only Remote Visiting, Thon Ly Oct 2026

Appreciation As World-Building: A Location-Based Virtual World Rendered From A User's Signed Ledger Instead Of Purchasable Cosmetics, With Location-Verified Content Creation And Read-Only Remote Visiting, Thon Ly

Defensive Publications Series

We disclose a location-based gratitude application built from geotagged user photographs. Each user's persistent virtual world, terrain and avatar, is rendered deterministically from that user's signed contribution ledger rather than furnished with purchasable cosmetic virtual goods: there is no store and no path from money to appearance, which lets a scheduled annual reset of ledger balances remain a forgiveness rather than a confiscation. Cosmetic forms unlock non-regressively on the first qualifying ledger pattern, with no display of locked items or progress, and a design-time test requires that unlockable sets not form a ranking ladder. Creating content, whether a capture or …

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