Digital Commons Network^™

Development Of A Bamlanivimab Infusion Process In The Emergency Department For Outpatient Covid-19 Patients, Danny Pham, Sandy Wong, Christina T. Nguyen, Stephen C. Lee, Kimberly J. Won

Pharmacy Faculty Articles and Research

The coronavirus disease 2019 (COVID-19) pandemic has prompted the creation of new therapies to help fight against the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Bamlanivimab is a SARS-CoV-2 monoclonal antibody that is administered as an intravenous infusion to ambulatory patients with mild or moderate COVID-19, but a concern that arose was deciding the optimal location for patients to receive the medication. This report describes the development and implementation of a bamlanivimab infusion center in the emergency department of three hospitals in Orange County, California, shortly after bamlanivimab received emergency use authorization. As a result, a total of 601 …

The Effect Of Hydroxychloroquine On Mortality In Hospitalized Covid-19 Patients, Misha Suresh, Jeff Abraham

Physician Assistant Capstones, 2020-current

As of October 2020, there are no commonly accepted or proven effective treatments for coronavirus disease 2019 (COVID-19). Hydroxychloroquine (HCQ) is an established anti-malarial drug with demonstrated action against SARS-CoV-2 (the virus that causes COVID-19) in-vitro and early observational studies and anecdotal evidence supported its use in treatment of COVID-19. In this review, three of largest and most statistically powerful studies to date (two cohort studies and one randomized controlled trial [RCT]) are synthesized for the purpose of determining whether HCQ is effective in reducing mortality in patients hospitalized with COVID-19. All three studies found no statistically significant difference in …

Phase 3 Safety And Efficacy Of Azd1222 (Chadox1 Ncov-19) Covid-19 Vaccine, Ann R Falsey, Magdalena E Sobieszczyk, Ian Hirsch, Stephanie Sproule, Merlin L Robb, Lawrence Corey, Kathleen M Neuzil, William Hahn, Julie Hunt, Mark J Mulligan, Charlene Mcevoy, Edwin Dejesus, Michael Hassman, Susan J Little, Barbara A Pahud, Anna Durbin, Paul Pickrell, Eric S Daar, Larry Bush, Joel Solis, Quito Osuna Carr, Temitope Oyedele, Susan Buchbinder, Jessica Cowden, Sergio L Vargas, Alfredo Guerreros Benavides, Robert Call, Michael C Keefer, Beth D Kirkpatrick, John Pullman, Tina Tong, Margaret Brewinski Isaacs, David Benkeser, Holly E Janes, Martha C Nason, Justin A Green, Elizabeth J Kelly, Jill Maaske, Nancy Mueller, Kathryn Shoemaker, Therese Takas, Richard P Marshall, Menelas N Pangalos, Tonya Villafana, Antonio Gonzalez-Lopez

Journal Articles

BACKGROUND: The safety and efficacy of the AZD1222 (ChAdOx1 nCoV-19) vaccine in a large, diverse population at increased risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the United States, Chile, and Peru has not been known.

METHODS: In this ongoing, double-blind, randomized, placebo-controlled, phase 3 clinical trial, we investigated the safety, vaccine efficacy, and immunogenicity of two doses of AZD1222 as compared with placebo in preventing the onset of symptomatic and severe coronavirus disease 2019 (Covid-19) 15 days or more after the second dose in adults, including older adults, in the United States, Chile, and Peru.

RESULTS: …

Adverse Childhood Experiences: Effects Of Covid-19, Evan Guo

Honors Projects

The evaluation of an adult's health status consists of several entities. These factors can include physical, mental, and emotional health in an individual's history contributing to their overall health. When studying such factors, some researchers emphasize the importance of recognizing events experienced during a person's childhood that affect their development, and therefore, their adult health status. Today, as people continue adapting to the COVID-19 pandemic and changes in regulation of standards for socialization, it is becoming apparent to healthcare researchers how these new modifications are highly impactful to the development of children and adolescents. When studying the various factors that …

Camping, Weather, And Disasters: Extending The Construal Level Theory, Christopher Craig, Siyao Ma, Ismail Karabas, Song Feng

Faculty & Staff Research and Creative Activity

Camping is an outdoor accommodation and type of recreation that is susceptible to weather and climate change. Camping—in addition to the relationships camping shares with weather— remains understudied despite the subsectors’ salient economic impact and high participation rate. The observable effects of non-meteorological/climatological (e.g., pandemic) is also a topic that has received limited attention. Accordingly, we introduce the Camping-Weather-Disaster (CWD) framework to examine the concurrent impact of weather and the COVID-19 disaster on post-disaster camping trip plans among leisure travelers in the 48 contiguous United States (n=2,442). Extending the Construal Level Theory, the CWD framework considers traveler construal (i.e., understanding) …

Improving Covid-19 Vaccination Awareness And Immunization In The African American Ages 55 And Up- A Quality Improvement Program, Lissa Fabienne Bazile

Nicole Wertheim College of Nursing Student Projects

The unprecedented health care effects, and consequences of COVID-19 have been felt disproportionately within distinctive races and older adults, especially African Americans. An individual’s race, comorbidities, age, and other determinants of health impact level of inclusion in society also influencing an individual’s susceptibility to developing COVID-19. Over 42 million people in the United States have tested positive for the COVID-19. Reluctance in the COVID-19 vaccination within the Black community can delay the closure of the race mortality gap seen with COVID-19.

Increasing COVID-19 vaccination awareness in Blacks ages 55 and older population at a South Florid a medical center using …

Parents’ Report Of Canadian Elementary School Children’S Physical Activity And Screen Time During The Covid-19 Pandemic: A Longitudinal Study, Emma Ostermeier, Patricia Tucker, Andrew Clark, Jamie A. Seabrook, Jason Gilliland

Paediatrics Publications

COVID-19 public health protocols have altered children’s daily routines, limiting their physical activity opportunities. The purpose of this study was to examine how the COVID-19 pandemic affected children’s (ages 10–12 years) physical activity and screen time, and to explore the impact of gender, socioeconomic status (SES), and public health constraints (i.e., facility use and social interaction) on the changes in children’s health behaviors. Online surveys were disseminated to parents at two time points: before COVID-19 (May 2019 to February 2020) and during COVID-19 (November to December 2020). Wilcoxon signed-rank tests were used to assess changes in physical activity and screen …

Acute Macular Neuroretinopathy Associated With Covid-19 Infection, James A. David, George D. Fivgas

School of Medicine Faculty Publications

Purpose: To report a case of bilateral acute macular neuroretinopathy (AMN) associated with a COVID-19 infection. Observations: A 22-year-old female was referred for evaluation of bilateral scotomas concurrent with a mildly symptomatic COVID-19 infection. Exam showed normal visual acuity, bilateral reddish-brown petaloid retinal lesions which were hyporeflective on near infrared (NIR) optical coherence tomography (OCT), and had associated hypoperfusion of the deep vascular plexus on OCT-angiography (OCT-A) consistent with bilateral AMN. At follow-up, scotomas and retinal findings on near infrared imaging and spectral-domain optical coherence tomography had only slightly improved. Conclusions: COVID-19 has been documented to be the etiology of …

Distillers' Grains: Past, Present, And Future Economic Analyses, Daniel E. Gertner

Department of Agricultural Economics: Dissertations, Theses, and Student Research

This thesis is comprised of four chapters, each of which discusses or conducts economic research related to the distillers’ grains market. The first three chapters are meant to be standalone papers. Chapter four provides potential paths forward in distillers’ grains research based on the findings of the first three chapters and concludes the thesis.

The first chapter conducts a comprehensive literature review that categorizes and summarizes economic research on distillers’ grains products. This section shows how the physical market has moved beyond the current academic understanding of market products and structure. Existing research finds that traditional distillers’ grains products positively …

Covid 19 & Qanon: Enter The World Of Conspiracies, Gianluca Allesina

Student Scholar Symposium Abstracts and Posters

From Covid-19 to Qanon to a global warming hoax, we live in a world drowning in misinformation spread on the internet. Q-anonymous, a purposed government “leaker” is an alleged high-level government informant, according to Qanon followers, who posted cryptic messages about a satanic government on the now-defunct forum website, 8chan. This project will examine the possible relationship between a belief in various conspiracy theories associated with Qanon and how the Coronavirus affected rates of belief, utilizing the Chapman Survey of American Fears, a national study using a representative sample of U.S. adults. I expect to find that partisanship will play …

No Future But A Shared Future, Lawrence O. Gostin, Kevin A. Klock, Sam F. Halabi, Katie Gottschalk, Katherine Ginsbach

Georgetown Law Faculty Publications and Other Works

The COVID-19 pandemic revealed the fractured and inadequate state of national and global health law and institutions, revealing deeply embedded inequalities. In response to a World Health Assembly resolution proposing a special session to consider the benefits of developing a WHO convention or other international instrument on pandemic preparedness and response, the O’Neill Institute for National and Global Health Law and the Foundation for the National Institutes of Health (FNIH) convened 30 of the world’s leading authorities on global health law, financing, biomedical science, implementation, and emergency response along with leaders from prominent international organizations deeply engaged in responding to …

Going Global, Acting Local: How An International Pandemic Convention Can Support Regional And Community Response, Kevin A. Klock, Lawrence O. Gostin, Sam F. Halabi

Georgetown Law Faculty Publications and Other Works

A WHO pandemic convention could set in place an overarching framework needed for strengthening global health security. As the World Health Assembly (WHA) debated the merits of such an agreement, a critically important regional instrument – the Treaty for the Establishment of the African Medicines Agency (AMA Treaty) – entered into force on 5 November 2021. The new agency will, among other things, ensure there is a “common framework” for addressing “emerging issues and pandemics in the event of a public health emergency on the continent with cross border or regional implications.”

An improved worldwide health security strategy is essential …

The Nature Of Anti-Asian American Xenophobia During The Coronavirus Pandemic: A Preliminary Exploration Into Envy As A Key Motivator Of Hate, Daisuke Akiba

Publications and Research

Background. The current Coronavirus pandemic has been linked to a dramatic increase in anti-Asian American and Pacific Islander (AAPI) hate incidents in the United States. At the time of writing, there does not appear to be any published empirical research examining the mechanisms underlying Asiaphobia during the current pandemic. Based on the stereotype content model, we investigated the idea that ambivalent attitudes toward AAPIs, marked primarily with envy, may be contributing to anti-AAPI xenophobia. Methods. Study 1 (N = 140) explored, through a survey, the link between envious stereotypes toward AAPIs and Asiaphobia. Study 2 (N = 167), …

Educating School Nurses: Returning To School During The Covid-19 Pandemic, Kelle Flynn-Gulley, Tracy L. Brewer

Graduate Publications and Other Selected Works - Doctor of Nursing Practice (DNP)

As schools began reopening, following government mandated school closure early on during the COVID-19 pandemic, new safety measures and protocols were put in place to keep students and staff safe. School nurses have become essential to ensuring schools reopen safely. However, as school nurses were forced to adapt to their increasing roles and responsibilities, a method for providing continuing education to school nurses within an East Tennessee school district did not exist. The goal of this evidence-based practice project was to provide continuing education to school nurses on COVID-19 return to school guidelines via an e-learning modality. Larrabee’s Model for …

Creative Adaptability And Emotional Well-Being During The Covid-19 Pandemic: An International Study, Hod Orkibi, Adar Ben-Eliyahu, Roni Reiter-Palmon, Ines Testoni, Gianmarco Biancalani, Vignesh Murugavel, Fei Gu

Psychology Faculty Publications

The putative associations between creative adaptability and the experience of emotional well-being (i.e., a positivity ratio of more positive than negative emotions) was investigated during the COVID-19 pandemic outbreak with a sample of 1,432 adults from four countries: Israel (n = 310), United States (n = 312), Italy (n = 378), and China (n = 569). Country differences and a mediation model for creative adaptability predicting emotional well-being through creative self-efficacy, resilient coping, and emotion regulation (reappraisal and suppression) were examined. The findings point to slight differences in countries, which are potentially due not only to the …

The Impact Of The Covid-19 Pandemic On People With Rheumatic And Musculoskeletal Diseases: Insights From Patient-Generated Data On Social Media, Katja Reuter, Atul Deodhar, Souzi Makri, Michael Zimmer, Francis Berenbaum, Elena Nikiphorou

Computer Science Faculty Research and Publications

Objectives

During the COVID-19 pandemic, much communication occurred online, through social media. This study aimed to provide patient perspective data on how the COVID-19 pandemic impacted people with rheumatic and musculoskeletal diseases (RMDs), using Twitter-based patient-generated health data (PGHD).

Methods

A convenience sample of Twitter messages in English posted by people with RMDs was extracted between 1 March and 12 July 2020 and examined using thematic analysis. Included were Twitter messages that mentioned keywords and hashtags related to both COVID-19 (or SARS-CoV-2) and select RMDs. The RMDs monitored included inflammatory-driven (joint) conditions (ankylosing spondylitis, RA, PsA, lupus/SLE and gout).

Results …

An Opportunistic Survey Reveals An Unexpected Coronavirus Diversity Hotspot In North America, Hon S. Ip, Kathryn M. Griffin, Jeffrey D. Messer, Megan E. Winzeler, Susan A. Shriner, Mary Lea Killian, Mia Kim Torchetti, Thomas J. Deliberto, Brian R. Amman, Caitlin M. Cossaboom, R. Reid Harvey, Natalie M. Wendling, Hannah Rettler, Dean Taylor, Jonathan S. Towner, Casey Barton Behravesh, David S. Blehert

USDA Wildlife Services: Staff Publications

In summer 2020, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was detected on mink farms in Utah. An interagency One Health response was initiated to assess the extent of the outbreak and included sampling animals from on or near affected mink farms and testing them for SARS-CoV-2 and non-SARS coronaviruses. Among the 365 animals sampled, including domestic cats, mink, rodents, raccoons, and skunks, 261 (72%) of the animals harbored at least one coronavirus. Among the samples that could be further characterized, 127 alphacoronaviruses and 88 betacoronaviruses (including 74 detections of SARS-CoV-2 in mink) were identified. Moreover, at least 10% (n …

Ua19/16/2 Women's Basketball Press Releases, Wku Athletic Media Relations

WKU Archives Records

Press releases, photos and game statistics for WKU women's basketball team from August to December 2021.

Reflections On Legal Education In The Aftermath Of A Pandemic, Timothy Casey

Faculty Scholarship

This essay considers two significant changes to legal education in the aftermath of the COVID-19 pandemic. First, on-line programs will expand, based on the largely successful experiment in delivering legal education on-line during the pandemic. But this expansion must be thoughtful and deliberate. The legal education curriculum could include more on-line courses, but only if the learning outcomes and the pedagogy are aligned with on-line education. Experiential courses may not be the best fit for on-line given the specific learning outcomes and the benefits of in-person instruction in those courses. Second, student well-being will receive more attention in legal education. …

Ua19/16/2 Basketball Press Releases, Wku Athletic Media Relations

WKU Archives Records

Press releases, photos and game statistics for WKU basketball team from August to December 2021.

Ua94/6/1 Pandemic Personal Narrative, Leah Painter

Student/Alumni Personal Papers

COVID-19 personal narrative written by student Leah Painter for History 241 class.

An International Agreement On Pandemic Prevention And Preparedness, Lawrence O. Gostin, Sam F. Halabi, Kevin A. Klock

Georgetown Law Faculty Publications and Other Works

During late 2021, national delegations are, or have, met at the United Nations General Assembly, the G20, and, most importantly, the Special Session of the World Health Assembly in November to determine whether the world needs a new international agreement to address pandemic prevention, preparedness, and response. The current international agreement, the International Health Regulations (2005), failed to work effectively – SARS-CoV-2 was not detected sufficiently early, relevant information was not shared efficiently, and the global response has not been coordinated. Even the most basic investigations were inadequate such as to discover the origins of SARS-CoV-2. Current proposals focus on …

Emergency Medicine And Covid-19: Now And Next Year, Theodore A. Christopher, Adrienne N. Christopher

Department of Emergency Medicine Faculty Papers

The COVID-19 pandemic is responsible for infecting to date more than 93 million people worldwide and causing more than 2 million deaths. That the vast majority of deaths have occurred in the United States (U.S.) can be attributed to nonadherence by Americans to basic public health mitigation strategies that are known to curtail coronavirus spread. Emergency Departments (ED’s) throughout the U.S. experienced a dramatic decrease in patient visits during the first surge of COVID-19, followed by an ED patient visit rebound to approximately 80% of pre-COVID-19 numbers, which have remained relatively stable through the current second COVID-19 surge. The pandemic …

University Schedules Vaccine Clinics Throughout Semester, Mitchell Diggs

University of Mississippi News

No abstract provided.

Voices From A Prison Pandemic: Lives Lost From Covid-19 At Lakeland Correctional, Kimberly Thomas

Articles

Coronavirus tore through jails and prisons like wildfire. In some states, more than half of the people incarcerated there tested positive for COVID-19; nearly 400,000 people in prison across the United States have tested positive. For people in prison, COVID-19 brought the loss of close friends, solitary confinement, loss of connection with family and programming, lack of information, and fear of contracting the virus. It has also reminded those who are incarcerated of the one-dimensional way in which people in prison are perceived. As stated by one collaborator, Cory Souders, "[s]o many men and women who come to prison are …

Taxation And Business: The Human Rights Dimension Of Corporate Tax Practices, Reuven S. Avi-Yonah

Book Chapters

The response of both developed and developing countries to global developments has been first, to shift the tax burden from (mobile) capital to (less mobile) labour, and second, when further increased taxation of labour becomes politically and economically difficult, to cut government services. Thus, globalization and tax competition lead to a fiscal crisis for countries that wish to continue to provide those government services to their citizens, at the same time that demographic factors and increased income inequality, job insecurity and income volatility that result from globalization render such services more necessary. This chapter argues that if government service programs …

Depression Screening By University Covid-19 Contact Tracers: Is It Feasible?, Lazara Medina

Nicole Wertheim College of Nursing Student Projects

The purpose of this DNP Project was to explore the feasibility of implementing a depression screening protocol as a component of COVID-19 contact tracing procedures. Multiple studies have established that in young adults, depression prevalence has increased during the pandemic. A cross-sectional 18-item survey was developed and administered with a convenience sample of contact tracers and administrators at a large public university. The transtheoretical model (also known as the stages of change model) developed by Drs. Prochaska and Diclemente (1992) guided the development of several survey items. Eleven people completed the web-based survey. Participants reported depression was a significant problem …

University Kicks Off Semester With Vaccination Clinics, Sydney Slotkin Dupriest

University of Mississippi News

Goal is to make vaccine accessible and convenient for all

Modeling The Effect Of The Covid-19 Pandemic On Azithromycin Prescription In General Practices Across The Uk, Oluwasegun Isaac Daramola

altREU Projects

In the early months of the COVID-19 pandemic, it was reported that some antibiotics were prescribed as a remedy for viral treatment and prophylaxis based on non-randomized, uncontrolled short clinical trials. A major antibiotic consulted being Azithromycin; a broad-spectrum macrolide selected based on its immunomodulatory effects in chronic inflammatory lung diseases, with a seasonal prescription increase of 21.5% in March 2020 compared to March 2019.

To analyze the effect and possible antimicrobial resistance impact of the pandemic on Azithromycin prescription across general practices in the United Kingdom (UK), this study uses a time series decomposition modeling method to compare a …

Probiotics In Prevention And Treatment Of Covid-19: Current Perspective And Future Prospects, Shilia Jacob Kurian, Mazhuvancherry Kesavan Unnikrishnan, Sonal Sekhar Miraj, Debasis Bagchi, Mithu Banerjee, B. Shrikar Reddy, Gabriel Sunil Rodrigues, Mohan K. Manu, Kavitha Saravu, Chiranjay Mukhopadhyay, Mahadev Rao

Faculty Publications

Saving lives and flattening the curve are the foremost priorities during the ongoing pandemic spread of SARS-CoV-2. Developing cutting-edge technology and collating available evidence would support frontline health teams. Nutritional adequacy improves general health and immunity to prevent and assuage infections. This review aims to outline the potential role of probiotics in fighting the COVID-19 by covering recent evidence on the association between microbiota, probiotics, and COVID-19, the role of probiotics as an immune-modulator and antiviral agent. The high basic reproduction number (R0) of SARS-CoV-2, absence of conclusive remedies, and the pleiotropic effect of probiotics in fighting influenza and other …