Digital Commons Network^™

High Fructose Corn Syrup Induces Metabolic Dysregulation And Altered Dopamine Signaling In The Absence Of Obesity, Allison M. Meyers, Devry Mourra, Jeff A. Beeler

Publications and Research

The contribution of high fructose corn syrup (HFCS) to metabolic disorder and obesity, independent of high fat, energy-rich diets, is controversial. While high-fat diets are widely accepted as a rodent model of diet-induced obesity (DIO) and metabolic disorder, the value of HFCS alone as a rodent model of DIO is unclear. Impaired dopamine function is associated with obesity and high fat diet, but the effect of HFCS on the dopamine system has not been investigated. The objective of this study was to test the effect of HFCS on weight gain, glucose regulation, and evoked dopamine release using fast-scan cyclic voltammetry. …

Patients’ Willingness To Participate In Rapid Hiv Testing: A Pilot Study In Three New York City Dental Hygiene Clinics, Susan H. Davide, Anthony J. Santella, Winnie Furnari, Petal Leuwaisee, Marilyn Cortell, Bhuma Krishnamachari

Publications and Research

Purpose: One in eight people living with an HIV infection in the United States is unaware of their status. Rapid HIV testing (RHT) is an easily used and accepted screening tool that has been introduced in a limited number of clinical settings. The purpose of this study was to investigate patient acceptability, certainty of their decision, and willingness to pay for screening if RHT was offered in university-based dental hygiene clinics.

Methods: A cross-sectional survey was administered to 426 patients at three dental hygiene clinics in New York City over a period of four months. The survey questionnaire was based …

Development And Validation Of The Microbiology For Health Sciences Concept Inventory, Heather M. Seitz, Rachel E. A. Horak, Megan W. Howard, Lucy W. Kluckhohn Jones, Theodore Muth, Christopher Parker, Andrea Pratt Rediske, Maureen M. Whitehurst

Publications and Research

Identifying misconceptions in student learning is a valuable practice for evaluating student learning gains and directing educational interventions. By accurately identifying students’ knowledge and misconceptions about microbiology concepts, instructors can design effective classroom practices centered on student understanding. Following the development of ASM’s Curriculum Guidelines in 2012, we developed a concept inventory, the Microbiology for Health Sciences Concept Inventory (MHSCI), that measures learning gains and identifies student misconceptions in health sciences microbiology classrooms. The 23-question MHSCI was delivered to a wide variety of students at multiple institution types. Psychometric analysis identified that the MHSCI instrument is both discriminatory and reliable …

Severe Uterine Bleeding, Catherine Olubummo

Publications and Research

No abstract provided.

The Farnesoid X Receptor Negatively Regulates Osteoclastogenesis In Bone Remodeling And Pathological Bone Loss, Ting Zheng, Ju-Hee Kang, Jung-Sun Sim, Jung-Woo Kim, Jeong-Tae Koh, Chan Soo Shin, Hyungsik Lim, Mijung Yim

Publications and Research

Farnesoid X receptor (FXR, NR1H4) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. Since the role of FXR in osteoclast differentiation remains ill-defined, we investigated the biological function of FXR on osteoclastogenesis, using FXR-deficient mice. We demonstrated that FXR deficiency increases osteoclast formation in vitro and in vivo. First, FXR deficiency was found to accelerate osteoclast formation via down-regulation of c-Jun N-terminal kinase (JNK) 1/2 expression. Increased expression of peroxisome proliferator-activated receptor (PPAR)γ and peroxisome proliferator-activated receptor gamma coactivator 1 (PGC- 1)β seems to mediate the pro-osteoclastogenic effect of FXR deficiency via the JNK pathway. In …

Pulling The Plug On Microscopes In The Anatomy And Physiology Laboratory, Zvi Ostrin, Vyacheslav Dushenkov

Publications and Research

Virtual microscopy (VM) has been widely available for more than a decade, especially in clinical settings and medical schools. In recent years the movement away from conventional optical microscopy (OM) and towards VM has been accelerating and several VM websites are now available online and readily accessible to educators. VM can enhance the instructor’s ability to teach the histology component of anatomy and physiology classes, facilitate student learning, save time for both students and instructors, and ultimately save money that can be more productively used for other facets of the laboratory. The many pedagogical and practical advantages provided by VM …

Caries Classification, Diana V. Macri, Annie Chitlall

Publications and Research

It has been 10 years since Featherstone and colleagues presented their evidence-based model of caries management: caries management by risk assessment (CAMBRA). This approach relies on a careful analysis of a patients’ risk factors and protective factors. International and national organizations have long recognized the need for a new caries classification system that incorporates evidence-based approaches to halt progression of caries lesions and minimize the need for surgical intervention. Thus, the International Caries Detection and Assessment System (ICDAS) and the American Dental Association Caries Classification System (ADA CCS) were created. The purpose of this article is to briefly review the …

Effects Of Synthetic Cannabinoid Use, Susan H. Davide

Publications and Research

Synthetic Cannabinoid Use: Oral health professionals need to be aware of the systemic and oral health effects of the substances in this class of drugs.

Public Health Research Priorities To Address Us Human Trafficking, Emily F. Rothman, Hanni Stoklosa, Susie B. Baldwin, Makini Chisolm-Straker, Rumi Kato Price, Holly G. Atkinson

Publications and Research

In this Perspective, HEAL Trafficking, the nation's leading public health anti-trafficking organization maps out a national research agenda to tackle the problem of human trafficking. Given the paucity of research on trafficking, HEAL Trafficking engaged its membership in a consensus development process throughout 2016 to develop its national research agenda. HEAL Trafficking proposes five priorities that public health researchers should focus on in the decade ahead to make meaningful progress on preventing and responding to human trafficking in the Unites States.

Mechanism Of Action For Rtms: A Working Hypothesis Based On Animal Studies, Thangavelu Soundara Rajan, Maria Felice Ghilardi, Hoau-Yan Wang, Emanuela Mazzon, Placido Bramanti, Domenico Restivo, Angelo Quartarone

Publications and Research

Experiments in rodents have elucidated some of the molecular mechanisms underlying repetitive transcranial magnetic stimulation (rTMS). These studies may be useful in a translational perspective so that future TMS studies in rodents can closely match human TMS protocols designed for therapeutic purposes. In the present work we will review the effects of rTMS on glutamate neurotransmission which in turn induce persistent changes in synaptic activity. In particular, we will focus on the role of NMDA and non-NMDA transmission and on the permissive role of BDNF-TrKB interaction in the rTMS induced after-effects.

For Social Justice, We Need To Look In The Mirror., Aldemaro Romero Jr.

Publications and Research

One of the most contentious issues in politics in general – and in higher education in particular – is political correctness.

Usually defined as the avoidance of language or actions that are seen as excluding, marginalizing, or insulting groups of people that have been dis- criminated against because of their gender, race, or other identifying factors.

The term is now oftentimes used in a pejorative sense, particularly in conservative circles.

Oldest Skeleton Of A Plesiadapiform Provides Additional Evidence For An Exclusively Arboreal Radiation Of Stem Primates In The Palaeocene, Stephen B. Chester, Thomas E. Williamson, Jonathan I. Bloch, Mary T. Silcox, Eric J. Sargis

Publications and Research

Palaechthonid plesiadapiforms from the Palaeocene of western North America have long been recognized as among the oldest and most primitive euarchontan mammals, a group that includes extant primates, colugos and treeshrews. Despite their relatively sparse fossil record, palaechthonids have played an important role in discussions surrounding adaptive scenarios for primate origins for nearly a half-century. Likewise, palaechthonids have been considered important for understanding relationships among plesiadapiforms, with members of the group proposed as plausible ancestors of Paromomyidae and Microsyopidae. Here, we describe a dentally associated partial skeleton of Torrejonia wilsoni from the early Palaeocene (approx. 62Ma) of New Mexico, which …

Legal Mapping Analysis Of State Telehealth Reimbursement Policies, Kate E. Trout, Sankeerth Rampa, Fernando A. Wilson, Jim P. Stimpson

Publications and Research

Background: There exists rapid growth and inconsistency in the telehealth policy environment, which makes it difficult to quantitatively evaluate the impact of telehealth reimbursement and other policies without the availability of a legal mapping database. Introduction: We describe the creation of a legal mapping database of state-level policies related to telehealth reimbursement of healthcare services. Trends and characteristics of these policies are presented.

Materials and Methods: Information provided by the Center for Connected Health Policy was used to identify state-wide laws and regulations regarding telehealth reimbursement. Other information was retrieved using: (1) LexisNexis database, (2) Westlaw database, and (3) retrieval …

Worldwide Use Of Triclosan: Can Dentistry Do Without This Antimicrobial?, Diana V. Macri

Publications and Research

No abstract provided.

The Olfactory System Revealed: Non-Invasive Mapping By Using Constrained Spherical Deconvolution Tractography In Healthy Humans, Demetrio Milardi, Alberto Cacciola, Alessandro Calamuneri, Maria F. Ghilardi, Fabrizia Caminiti, Filippo Cascio, Veronica Andronaco, Giuseppe Anastasi, Enricomaria Mormina, Alessandro Arrigo, Daniele Bruschetta, Angelo Quartarone

Publications and Research

Although the olfactory sense has always been considered with less interest than the visual, auditive or somatic senses, it does plays a major role in our ordinary life, with important implication in dangerous situations or in social and emotional behaviors. Traditional Diffusion Tensor signal model and related tractography have been used in the past years to reconstruct the cranial nerves, including the olfactory nerve (ON). However, no supplementary information with regard to the pathways of the olfactory network have been provided. Here, by using the more advanced Constrained Spherical Deconvolution (CSD) diffusion model, we show for the first time in …

The Effect Of Object-Centered Instructions In Cartesian And Polar Coordinates On Saccade Vector, Jay A. Edelman, Alexa M. Mieses, Kira Konnova, David Shiu

Publications and Research

Express saccades (ES) are the most reflexive saccadic eye movements, with very short reaction times of 70– 110 ms. It is likely that ES have the shortest saccade reaction times (SRTs) possible given the known physiological and anatomical delays present in sensory and motor systems. Nevertheless, it has been demonstrated that a vector displacement of ES to spatially extended stimuli can be influenced by spatial cognition. Edelman, Kristjansson, and Nakayama (2007) found that when two horizontally separated visual stimuli appear at a random location, the spatial vector, but not the reaction time, of human ES is strongly influenced by an …

Neurophysiological And Behavioral Responses Of Mandarin Lexical Tone Processing, Yan H. Yu, Valerie L. Shafer, Elyse S. Sussman

Publications and Research

Language experience enhances discrimination of speech contrasts at a behavioral- perceptual level, as well as at a pre-attentive level, as indexed by event-related potential (ERP) mismatch negativity (MMN) responses. The enhanced sensitivity could be the result of changes in acoustic resolution and/or long-term memory representations of the relevant information in the auditory cortex. To examine these possibilities, we used a short (ca. 600 ms) vs. long (ca. 2,600 ms) interstimulus interval (ISI) in a passive, oddball discrimination task while obtaining ERPs. These ISI differences were used to test whether cross-linguistic differences in processing Mandarin lexical tone are a function of …

Diversity More Than Race, Gender In Higher Ed., Aldemaro Romero Jr.

Publications and Research

Most people when talking about diversity think

of matters revolving around race and gender, and

while those are obvious and important topics, the

fact of the matter is that the definition of diversity

is much larger.

Today diversity is seen in two dimensions.

The first one is what is called inherent diversity,

the diversity that is beyond people’s control.

Obviously, these issues include race and gender,

but also include national origin, age, sexual orientation,

disability, religious affiliation and socioeconomic

status. Certainly, you can change your

religious affiliation or socioeconomic status over

time, but being raised in a particular religion or …

Protein Calorie Malnutrition, Nutritional Intervention And Personalized Cancer Care, Anju Gangadharan, Sung-Eun Choi, Ahmed Hassan, Nehad M. Ayoub, Gina Durante, Sakshi Balwani, Young Hee Kim, Andrew Pecora, Andre Goy, K. Stephen Suh

Publications and Research

Cancer patients often experience weight loss caused by protein calorie malnutrition (PCM) during the course of the disease or treatment. PCM is expressed as severe if the patient has two or more of the following characteristics: obvious significant muscle wasting, loss of subcutaneous fat; nutritional intake of <50% of recommended intake for 2 weeks or more; bedridden or otherwise significantly reduced functional capacity; weight loss of >2% in 1 week, 5% in 1 month, or 7.5% in 3 months. Cancer anorexiacachexia syndrome (CACS) is a multifactorial condition of advanced PCM associated with underlying illness (in this case cancer) and is characterized by loss of muscle with or without loss of fat mass. Cachexia is defined as weight loss of …

Incentives To Change: Effects Of Performance-Based Financing On Health Workers In Zambia, Gordon C. Shen, Ha Thi Hong Nguyen, Ashis Das, Nkenda Sachingongu, Collins Chansa, Jumana Qamruddin, Jed Friedman

Publications and Research

Background: Performance-based financing (PBF) has been implemented in a number of countries with the aim of transforming health systems and improving maternal and child health. This paper examines the effect of PBF on health workers’ job satisfaction, motivation, and attrition in Zambia. It uses a randomized intervention/control design to evaluate before–after changes for three groups: intervention (PBF) group, control 1 (C1; enhanced financing) group, and control 2 (C2; pure control) group.

Methods: Mixed methods are employed. The quantitative portion comprises of a baseline and an endline survey. The survey and sampling scheme were designed to allow for a rigorous impact …

Vowels Of Beryozovka Ewen: An Acoustic Phonetic Study, Kang Hijo, Yun Jiwon, Seongyeon Ko

Publications and Research

This study acoustically analyzes 13,540 vowel tokens of Beryozovka Ewen with the aid of automated post-transcriptional processing technique. The focus of the analysis is on the acoustic correlates of [RTR], which is the harmonic feature of the language. In addition to the first three formants, acoustic values representing spectral tilt such as H1−H2, H1−A2, and B1 are measured as potential acoustic cues of [RTR]. The results show that F1, F3, and B1 are the most reliable cues of the feature and that H1− H2 and H1−A2 are nearly reliable. These acoustic cues are also shown to interact with length and …

Reading Effectively Across The Disciplines (Read): A Strategy To Improve Student Success, Juanita But, Pamela Brown, Davida Smyth

Publications and Research

This paper describes the structure and activities of READ (Reading Effectively Across the Disciplines), a pilot initiative to improve students’ critical reading skills, disciplinary literacy and academic success. READ employs a multimodal design that consists of faculty training in disciplinary literacy instruction and curricular enhancement, development and implementation of active reading assignments and assessments, peer-led team learning, and the dissemination of discipline-specific teaching and learning resources on an Open Lab site to provide an interactive teaching and learning environment for students and faculty. Empirical evidence of the initial effectiveness of the pilot in three gateway courses in Biology, Electromechanical Engineering …