Digital Commons Network^™

Development Of A Novel Bioink For Human Vascularized Organoids, Bradley Allen Bromet

Masters Theses

"There is a need for a model to better mimic human physiology in the clinic, so the objective was to develop a novel bioink for a 3D tissue model to study human disease and development in a dynamic 3D environment. The results from each corresponding study helped in developing a novel bioink for use in a bio printed human vascularized organoid. The bioink composed of alginate with other natural hydrogels to function as extracellular matrix and with the addition of borophosphate bioactive glasses (BPBGs) to replace growth factors, can be used with multiple cell types to bio print the proposed …

Approximate And Sample Entropy Of Center Of Pressure In Unperturbed Tandem Standing: Contribution Of Embedding Dimension And Tolerance, Jayla Mashae Wesley

Masters Theses

Approximate entropy (ApEn) and sample entropy (SampEn) are statistical methods designed to quantify the regularity or predictability of a time series. Although ApEn has been a prominent choice for use, it is currently unclear as to which method and parameter selection combination is optimal for its application in biomechanics. The goal of this thesis was to examine the difference between ApEn and SampEn related to center of pressure (COP) data during standing balance tasks, while also refining tolerance r, to determine entropy optimization. Six participants completed five 30-second, feet together and tandem standing, trials under eyes-open and eyes-closed conditions. Ground …

Cfd Analysis Of Subcutaneous Deposition And Dispersion Of Insulin In Adipose Tissue, Ryan C. Lubbers

Masters Theses

Drug delivery is the most important factor of many therapies, but a lack of technology and research have led to a very generalized understanding of drug kinetics. Insulin pump therapy for the treatment of Type 1 Diabetes depends on precise delivery of the hormone into the adipose region between the dermis and underlying muscle. The kinetics of insulin within the adipose tissue environment is not well understood and varies greatly case to case. The use of computation fluid dynamics (CFD) models to study insulin kinetics in relation to influential factors will lead to a better understanding of the characteristics of …

Development Of A Highly Sensitive Pressure Sensing System With Custom-Built Software For Continuous Physiological Measurements, Masoud Panahi

Masters Theses

In this work, a pressure sensing system was designed and fabricated by developing a highly sensitive cone-structured pressure sensor with a custom-built software for physiological monitoring applications. A novel highly sensitive cone structured porous polydimethylsiloxane (PDMS) based pressure sensor capable of detecting very low-pressure ranges was developed for respiration monitoring. The pressure sensor was fabricated using a master mold, a hybrid-structured dielectric layer, and fabric-based electrodes. The master mold with inverted cone structures was created using a rapid and precise three-dimensional (3D) printing technique. The dielectric layer, with pores and cone structures, was prepared by annealing a mixture of PDMS, …

Sensory Refreshment: Tcm Reconsidered, Ni Tang

Masters Theses

With the rapid development and expansion of our cities and the economic demand placed on residents, city dwellers are under more personal stress than ever. Long commutes, overtime work, irregular rest, unhealthy diets, urban pollution and noise all adversely impact wellbeing. These unhealthy conditions overwhelm the mind and make residents mentally and physically sub-healthy. Sub-health is a state between complete health and sickness, which is especially common in large cities. The sub-health rate in Shanghai and Beijing has reached more than 70%.

Chinese medicine can regulate the human body from a holistic perspective and help solve sub-health problems. Chinese medicine …

Zoomorphic Extended Body, Nicholas Tamas

Masters Theses

My thesis work is built around emerging technologies within the fields of prosthetic and robotics. The end result is a speculative proposal with how to expand the potential modes of use with these emerging technologies to extend and build upon their potential uses.

Hormonal Responses To Seasonal Thermal And Ecological Stressors In Japanese Macaques (Macaca Fuscata), Lilianne Nelson

Masters Theses

Relative to most primate species, Japanese macaques (Macaca fuscata) experience extreme seasonal variation in thermal and ecological stressors that can impact energetic demands. To cope with these environmental changes, levels of metabolic hormones, such as cortisol and triiodothyronine, fluctuate to facilitate energetic adjustments. While previous research in primates has investigated thermal and ecological stressors individually, a combined assessment of these stressors alongside hormone levels can provide a more holistic understanding of the relationship between a primate’s thermoregulation, energetic balance, and stress. The goals of this study were to determine the effects of season, temperature and ecological stress on …

Analysis Of Center Of Pressure And Center Of Mass To Determine Patterns Of Postural Stability In Neurotypical Subjects, Natalie Tipton

Masters Theses

The body’s postural control mechanism is responsible for responding to perturbations of balance and keeping the body upright. One of the main ways that this is completed during quiet standing, where both feet are planted on the ground, is through center of pressure oscillations. In these oscillations, the center of pressure circles around the center of mass, constantly counteracting any lean that exists in the body. These oscillations can be recorded with floorembedded force plates and center of mass can be recorded with a motion capture system. In this research, these signals were recorded for stances with feet together and …

Flexible Capacitive Pressure Sensors And Triboelectric Energy Harvesters Using Laser-Assisted Patterning Process For Flexible Hybrid Electronic Applications, Valliammai Palaniappan

Masters Theses

This work focuses on the design, fabrication and characterization of novel flexible capacitive pressure sensors and triboelectric energy harvesters using laser-assisted patterning process for flexible hybrid electronic applications. Initially, the capacitive pressure sensor was developed by fabricating a set of polydimethylsiloxanes (PDMS) dielectric films with pyramid shaped micro-structures using a laser-assisted patterning process. The pressure sensor consists of two electrodes (top and bottom) that were fabricated by depositing silver (Ag) on flexible polyethylene terephthalate (PET) using additive screen-printing process. Finally, the pressure sensor was assembled by attaching the top and bottom Ag electrodes to the smooth side of pyramid shaped …

The Influence Of Environment: A Holistic Approach To Middle And Secondary Art Room Design, Leslie Y. Roberts

Masters Theses

This thesis takes an in-depth look at the elements within the classroom and how they affect students physiological and psychological needs and the impact those elements have on students’ academic success. I offer suggestions based on the research for changes that can be made to your current environment to increase students’ academic success. Additionally, through years of experience and additional research on classroom environments within this thesis I have created a floor plan for an ideal middle and high school art wing. This thesis also covers several different approaches to teaching, and I have used this information plus my experience …

Fluid Flow In A Krogh Cylinder: A Model For A Single Capillary And Surrounding Tissue, Xianjie Qiu

Masters Theses

"A model describing the flow of plasma from the capillaries to the interstitial space in the extravascular tissue and back into the capillaries is constructed and solved. The flow through the tissue or the interstitial spaces is described by the Brinkman equation for porous medium, modified to account for the presence of cells considered as spheres. The flow of blood through the capillaries is considered to be that of a Newtonian fluid. The flow between capillary and tissue is coupled by the permeability of the capillary wall. The nature of flow and its magnitude was found to be highly dependent …

Visualization Of The Cardiac Excitation And Pvc Arrhythmia On A 3d Heart Model, Pranav Sreedharan Veliyara

Masters Theses

Visualization of the cardiac potential movement is important in understanding the physiology of the human heart. A 3D visualization tool will help the cardiology students and others interested in human physiology to understand the functioning of the heart. In this thesis, such a tool is proposed which helps in the visualization of the cardiac potential movement and Premature Ventricular Contraction (PVC) event on a 3D heart model. The cardiac excitation obtained from a limb lead and a precordial lead of a 12 lead electrocardiograph (ECG) is mapped on a 3D heart model with fixed conduction pathways. The 3D heart model …

How Long Can You Hold Your Breath?, Felicia Leroy

Masters Theses

I began freediving, a sport in which one dives as deep as possible on single breath hold, as a way to approach the inaccessible space of the deep, to expand my understanding of the unobtainable.

This space (the deep) seemed to me to be representative of something that is totally unknown, its power existing in its inaccessibility, in its un-know-ability.

Through training/experiential data collection and using human physiology at depth as a framework, this thesis work book explores a single breath hold to the other side.

Work made in support of this exploration touches on darkness, depth, the edge, the …

A Transcutaneous Data And Power Transfer System For Osteogenesis Monitoring Sensors, Deepak Dileepkumar

Masters Theses

Implant devices are widely used in health care applications such as life support systems, patient rehabilitation devices and patient monitoring devices. Medical implants have enabled physicians to obtain relevant real time information regarding an organ, or a site of interest with in the body and suggest treatment accordingly. In some cases, the position of the implant within the body or threats of infections prevents wired communication techniques to extract information from the implant. Wireless communication is the alternative in such cases. Distraction osteogenesis is one such application where wireless communication can be established with callus growth monitoring sensors to obtain …

The Color Of The Year: A Textual Analysis Of Pantone’S Color Communication Techniques Through The Application Of Barthes’ Semiotic, Kyung Lee

Masters Theses

This research analyzes the content of Pantone’s color of the year in 2000, 2002, 2009, 2014 and 2015 utilizing Barthes’ semiological system from a communication perspective. This study scrutinizes the announcement of Pantone’s color of the year as well as its color story to discover the purpose and the effectiveness of the verbalized nomination. The result reveals the significance of the semantic nature, which directs individuals’ viewpoint and creates a new connotation to alter their preconception. Also, Pantone’s color of 2014, Radiant Orchid, verified that the consolidation of the visual image and verbal content can maximize the influences that the …

Oxidized Phospholipids Regulation Of The Monocyte Recruitment Parthway In Human Aortic Endothelial Cells, Piao Jian Tan

Masters Theses

Low-density lipoprotein particles in blood plasma invade the endothelium and become oxidized, creating risk of CHD associated with atherosclerosis, the main underlying condition in coronary heart disease. Oxidation products of the phospholipid 1-palmitoyl- 2-arachidonoyl-sn-glycerol-3-phosphatidylcholine (PAPC) are bioactive components of minimally oxidized LDL that stimulate endothelial cells that line the artery, leading to monocyte binding and atherosclerosis. It is hypothesized that the regulation of the monocyte recruitment pathway by these oxidized phospholipids is mediated by the binding of OxPAPC to one or more mediating proteins. Human recombinant VEGFR2, GRP78, and EP2bind to OxPNB, a biotinylated analog of OxPAPC, demonstrated using Western …

Effects Of Various Partial Body Cooling Techniques On Core Temperature During Recovery From Prolonged Cycling-Induced Heat Stress, Afton Danielle Seeley

Masters Theses

The purpose of this study was to investigate the effects of using an ice-vest and a palm cooling device on core and skin temperatures, heart rate, and perceived thermal comfort during a one hour recovery period following exercise in the heat. Ten recreationally active adults cycled for one hour at 50% V0₂ peak on a cycle ergometer while exposed to 36°C 45%relative humidity environmental conditions. Following exercise, each subjectwas exposed to an ice vest, a palm cooling device, or a non cooling control while seated in the environmental chamber for 60 more minutes. No significant differencewas found betweenany of …

Role Of Nicotine In Oxidative Stress, Rakesh Kacham

Masters Theses

"Nicotine, a major alkaloid, is present in tobacco products as well as in smaller amounts in potatoes, tomatoes, and eggplants. Although it is the addictive compound in cigarettes, nicotine is believed to play a protective role in neurodegenerative disorders such as Parkinson's disease. Researchers have found that the short-term administration of nicotine may help improve the memory process by reducing oxidative stress in the brain. Our studies have shown that, by blocking Fenton's reaction, nicotine is able to inhibit free radical generation, so this research has focused on the antioxidant properties of nicotine. The cell lines of the alveoli, blood …

The Maturation Of Pulse: The Rhythmic Evolution From Swing To Bebop, Sam Weber

Masters Theses

The musical style that came to prominence in US in the 1940s, known as bebop, is a style that is remembered and discussed in terms of its harmonic characteristics and its notable soloists. This is the view that is taken in most scholarly writing on the music and also the view that is taught to most students of jazz today. However, there is arguably an equally if not more profound evolution in the rhythmic language of this music which is almost totally un-discussed. By digitally analyzing recordings, tracing musical and personal influence, and by examining related technological developments, it becomes …

Student Athletes' Perceptions Of Academic Support, Career Support And Personal Support, Chandra R. Golden

Masters Theses

The purpose of this research was to explore the perceptions of student athletes concerning self identity, academic support, career support, and personal support. Qualitative methodology was used to gather information through in-depth focus groups. Participants were male and female student athletes from a mid-size Midwestern Public University.

Findings indicated there is an inherent struggle to balance multiple roles with one usually elevated over the other. Second, participants appreciated the academic support of the university, but indicated its influence ranged from extremely helpful and appreciated (Athletic Academic Support Staff) to moderately helpful (Major Specific Academic Advisors) to least helpful (Regular Academic …

Home: A Concept Analysis With Application Of The Concept To Experiences Of Individuals With Serious And Persistent Mental Illness, Corinne A. Overmyer

Masters Theses

The purpose of this paper was to explore and define the concept of home through an extensive review of the literature. The concept analysis framework of Walker and Avant (1995) was used to structure the paper and the theories of Johnson (1980) and Maslow (1954) were used for operationalization. The literature search examined characteristics of home applicable to all individuals. The concept’s defining attributes were discovered and applied to the home experiences of those living with serious and persistent mental illness. Homes were evaluated to assess for attribute presence and to determine if the homes were model, borderline, or contrary. …

Hormone Replacement Therapy: Attitudes, Knowledge, And Usage By Perimenopausal And Postmenopausal Women, Misty Lynn Rhoads

Masters Theses

With an increased life expectancy, women are living an average of 30 yearars after the set of menopause. With the change in life, there is a significant change in t onse the production of female hormones which causes unpleasant side effects that includes hot flashes, osteoporosis, nausea, and palpitations. Hormone replacement therapy was promoted to provide relief for women. However, research has shown that HRT may increase the risk of endometrial cancer, strokes and breast cancer. Therefore, women are given contradictory information concerning HRT. The current study explored the attitudes, knowledge and intentions of perimenopausal and postmenopausal women concerning hormone …

Athletic Trainers' Perceptions Of Competence In Therapeutic Exercise, Christopher J. Jones

Masters Theses

As the athletic training profession continues to expand, it is necessary to evaluate the preparedness of the entry-level certified athletic trainer (ATC). The purpose of this research is to determine if entry-level certified athletic trainers perceive that they have the knowledge and skills necessary to perform specific tasks related to therapeutic exercise.

An online questionnaire was sent out to 450 entry-level certified athletic trainers in District Four. A total of 69 subjects returned the survey for a response rate of 15.3%. The questionnaire utilized a Likert-type scale consisting of questions derived in the area of therapeutic exercise of the NATA …

Olfactory Behavior In Apoe Knockout Mice, John P. Yost

Masters Theses

Apolipoprotein E (apoE), a lipid transporting protein, has been shown to play a vital role in nerve repair and remodeling. Since the olfactory system is in a continuous state of remodeling, the present study tested the hypothesis that apoE is required for normal functioning of the olfactory system. Olfactory function of the wild type (WT) and apoE deficient (apoE KO) mice was assessed by using three standard olfactory tests: 1) the buried food pellet (BFP) test; 2) the odor choice (OC) test; and 3) the odor cued taste avoidance (OCTA) test. The visible food pellet test (VFP) was not used …

Re-Cycling The Menstrual Cycle: A Multidisciplinary Reinterpretation Of Menstruation, Heather H. Rea

Masters Theses

This thesis offers a reinterpretation of the human female menstrual cycle that understands the process as positive, functional, and practical experience. Standard western definitions and understandings of menstruation use negative terminology and focus on menstrual blood as an indicator of failed conception. This view contributes significantly to the negative perception women have of menstruation in general, their own menstrual cycles, and ultimately of their femaleness. This fundamental, physiological process that symbolizes femaleness, the menstrual cycle, has been defined both, bio-medically and culturally, as a negative experience. I propose a reconceptualization of the menstrual cycle that is not only a tool …

The Effects Of Chromium Picolinate Supplementation On Body Fat, Lean Body Mass, And Respiratory Exchange Ratio, Matthew K. Beaty

Masters Theses

The purpose of this study was to investigate the effects, on college-age males, of ingesting chromium picolinate over a 6-week period when administered as a supplement to their diet. Fifty males, ages 18 to 25 years, had their respiratory exchange ratio (R), body fat percentage, and lean body mass measured prior to and following a 6-week supplementation period. Subjects were randomly placed into a chromium, placebo, or control group. All subjects were instructed to maintain daily activities. Analysis of variance revealed no significant differences in R values, body fat percentage, or lean body mass among the chromium, placebo, or control …

A Preliminary Study In The Design Of A Stress Inventory For Gifted Students: A Factor Analysis Of Potential Items, David Kinkade

Masters Theses

Items were designed for potential utilization in a stress inventory for gifted students. Two types of items were written; the first assessing stressful life events and situations, the second assessing coping ability. Both sets of items were administered to gifted students (N = 162) currently enrolled in the seventh and eighth grades. A principle components factor analysis with a varimax rotation was performed on both sets of items separately. The first set produced a four factor solution. The factors which emerged were identified as self-concept of giftedness, positive gifted programming, negative aspects of the gifted label, and performance pressure. The …

The Effects Of Aids Education On Knowledge And Health Care Beliefs Of Freshman Nursing Students, Suzanne M. Nahan

Masters Theses

The purpose of this study was to examine the effects of AIDS education on knowledge and health care beliefs of freshman nursing students. It was hypothesized that freshman nursing students presented with AIDS instruction would have more AIDS knowledge than freshman student nurses without AIDS instruction. In addition, it has hypothesized that the strength of health care beliefs related to AIDS susceptibility, seriousness, benefits, barriers and health motivation of freshman nursing students with AIDS instruction would differ from those without AIDS instruction.; A quasi-experimental control group pretest/posttest design was used. The sample consisted of 50 freshman student nurses enrolled in …

The Effect Of Insulin Mimetics On Enzymes Of Fatty Acid Biosynthesis, Eric A. Berg

Masters Theses

Fatty acid biosynthesis, an insulin regulated pathway, is the process of producing fatty acid chains from 2 and 3 carbon units. Two enzymes in this pathway that insulin affects are glucose-6-phosphate dehydrogenase (G6PDH) and fatty acid synthase (FAS). Sodium vanadate and sodium selenate have demonstrated insulin-like effects in several tissue and cell types. These mimetic effects include increasing glucose transport, regulating glycolytic enzymes, normalizing plasma glucose levels and activities of insulin regulated enzymes in diabetic rats. Our goal was to examine effects of sodium vanadate and sodium selenate on fatty acid biosynthesis in two insulin responsive systems: Isolated rat hepatocytes …

The Effect Of Horseback Riding Activity On The Tibialis Anterior, Vastus Lateralis, And Rectus Abdominis Of A Paraplegic, Laurie A. Price

Masters Theses

Horses are now being used in various programs under various conditions. The use of horses for therapy and recreation for the physically and mentally disabled first began in Germany and Switzerland. The United States now has many schools and different riding programs as well.

Riding seems to be especially beneficial to those with neurological impairments. Treatment of paraplegia is very limited but recreational activities are advancing. The use of the horse is beneficial for paraplegics emotionally as well as physically. Measurements and evaluations of these benefits are lacking. This project analyzes and measures the physical benefits of horseback riding on …