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Serotonin And Its Effects On The Chronic Stress Response In Crayfish Following Nonylphenol Exposure, Tara M. Olen May 2023

Serotonin And Its Effects On The Chronic Stress Response In Crayfish Following Nonylphenol Exposure, Tara M. Olen

Masters Theses

Current research suggests that stress in both vertebrates and invertebrates is modulated in part by the neurotransmitter serotonin. It has been shown that crayfish can function as a good neurophysiological model, as they have less complex neurological systems than vertebrates, so mechanistic causes for stress can be more readily studied and understood. One potential stressor for aquatic species such as crayfish would be nonylphenol, a hydrophobic chemical used in agricultural products that can make its way into the water supply due to agricultural runoff. Nonylphenol can lead to physiological and behavioral impairments in crayfish and these impairments likely induce stress …


Influences Of Chronic Stress On Irritable Bowel Syndrome, Anxiety, Depression, And The Microbiome, Julia A. Semaan May 2023

Influences Of Chronic Stress On Irritable Bowel Syndrome, Anxiety, Depression, And The Microbiome, Julia A. Semaan

Masters Theses

IBS effects approximately 5% of the world’s population with symptoms ranging from unexplainable constipation to daily abdominal pain. Though treatment options are available and have been proven beneficial for certain individuals, discovering the root cause of IBS has been difficult to accomplish due to the variety of symptoms that differ from case to case. This study aims to increase understanding of the influence that chronic stress has on irritable bowel syndrome, anxiety, depression, and the microbiome in the college-age population since this group is likely to experience daily stressors, anxiety- and depressive-like thoughts, as well as IBS symptoms. Current research …


Social Dominance Alters Stress-Induced Neural Activity And Generates Individual Differences In Stress Vulnerability, Jenna Lee Laymon May 2023

Social Dominance Alters Stress-Induced Neural Activity And Generates Individual Differences In Stress Vulnerability, Jenna Lee Laymon

Masters Theses

Identifying the physiological and behavioral mechanisms that underlie stress vulnerability is a crucial step toward identifying novel targets for the prevention and treatment of stress-related disorders. Social status is a key environmental factor that contributes to individual variations in stress vulnerability. In particular, achieving a subordinate social status has been shown to produce susceptibility to anxiety-like and depressive-like behavior. In this project, our aim was to identify neural ensembles regulating how dominance status modulated stress-induced changes in avoidant behavior in male and female Syrian hamsters. Using a viral vector that codes for robust activity marker (RAM), we investigated whether stress-induced …


Does Need For Social Support Moderate The Relationship Between Perceived Availability Of Social Support And Depression, Anxiety, And Stress?, Katherine E. Whisenhunt Jan 2023

Does Need For Social Support Moderate The Relationship Between Perceived Availability Of Social Support And Depression, Anxiety, And Stress?, Katherine E. Whisenhunt

Masters Theses

This study was designed to determine whether the need for social support moderates the relationship between social support (both perceived and enacted) and depression, anxiety, and stress. The study tested the role of Need for Support in the context of both buffering and direct effect models of the effect of social support on mental health and well-being. If perceived availability of social support (i.e., PASS) had a direct effect on well-being, then a simple moderation was predicted. If a buffering effect was present, then a moderated moderation was predicted. This study also predicted a positive relationship between need for social …