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Study Of Protein-Protein Interaction By Using In-Cell Nmr In Human Cells, Asma Salem M Aldousary Jan 2016

Study Of Protein-Protein Interaction By Using In-Cell Nmr In Human Cells, Asma Salem M Aldousary

Legacy Theses & Dissertations (2009 - 2024)

We developed a new technology to study protein-protein interaction in mammalian cells. This technology is based high resolution of Nucleic Magnetic Resonance (NMR) spectroscopy. Using this technology we studied interaction between the receptor for advanced glycation endproducts (RAGE). RAGE- is a multiligand receptor of immunoglobulin receptor family that is activated by a multitude of ligands. Activation of RAGE results in signal transduction that leads to the inflammatory response implicated in the complications of Diabetes. RAGE is an emergent drug target that has been explored for the variety of pathologist including cancers, neurological disorders, inflammatory disease, and diabetes. and Intracellular effector …


The Conversion Of The Anglo-Saxon Kings, Marc Beneduci Jan 2016

The Conversion Of The Anglo-Saxon Kings, Marc Beneduci

Legacy Theses & Dissertations (2009 - 2024)

This thesis examines the history of the establishment of the Anglo-Saxon practice of kingship and explores the conversion of that institution from a native and traditional pre-Christian political apparatus into one of autocratic Christian rule. By examining this period of history and studying the infiltration of foreign cultural elements, this study explores and discusses the ways in which the Anglo-Saxon regnal society was fundamentally transformed from an archetypal representation of the Germanic heroic age into one with a synthesis with aspects of Christian rule and religiosity. The nature of the time period requires alternative methods of historic understanding to be …


From Myplate To Mcteacher's Night : A Communication-Centered And Ecological Investigation Of Nutrition Education In Middle School : A Case Study, Crystal Lee Brandow Jan 2016

From Myplate To Mcteacher's Night : A Communication-Centered And Ecological Investigation Of Nutrition Education In Middle School : A Case Study, Crystal Lee Brandow

Legacy Theses & Dissertations (2009 - 2024)

We have an undeniable awareness about the rates of obesity in our country, and we know that rates of obesity among children and youth are higher than ever. In fact, this is predicted to be the first generation of children who will not live longer than their parents. An abundance of research has identified the challenges and the causes of childhood obesity, and even proposed solutions for addressing this growing public health concern. One of the suggested solutions, or at least preventative measures, involves schools playing an active role in combating the obesity epidemic through the provision of nutrition interventions. …


Essays On Patenting, R & D And Technological Innovation, Na Cheng Jan 2016

Essays On Patenting, R & D And Technological Innovation, Na Cheng

Legacy Theses & Dissertations (2009 - 2024)

The innovative activities by firms are considered to be the main driving force of the economic growth. The patent data has been widely used to investigate the relationship between R&D and patents which are taken as an output indicator of the new invention or innovation. On the other hand, empirical evidence supports that teamwork of inventors fosters innovation and technological progress. Motivated by the importance of understanding the patenting behavior of firms and collaboration of inventors, we exploit the continuing applications of patents, examine the R&D and patents relationship, and investigate the effects of teamwork on innovation output.


Accessing Alternative Response Services : A Multi-Level Examination Of Family And Community Characteristics On Racial Equity, Tana D. J. Connell Jan 2016

Accessing Alternative Response Services : A Multi-Level Examination Of Family And Community Characteristics On Racial Equity, Tana D. J. Connell

Legacy Theses & Dissertations (2009 - 2024)

Although research has identified factors associated with child welfare involvement, less attention has been given to how Black families are assigned to types of child welfare services. The advent of alternative response pathways allows child protective workers to assign child abuse prevention services to families based on the type and seriousness of the maltreatment, history of prior reports and age of the child. Given the history of disparate outcomes in child welfare for Black families and the fact that alternative response pathways are a promising approach for improving outcomes for families, this study examines the effect of family and community …


Factors Associated With Cognitive Development Of Primary School Children In Eastern Indonesia, Nisa Felicia Jan 2016

Factors Associated With Cognitive Development Of Primary School Children In Eastern Indonesia, Nisa Felicia

Legacy Theses & Dissertations (2009 - 2024)

Reasoning, pattern recognition, and problem solving are key cognitive skills developed during


Three Essays On The Global Financial Crisis And Fiscal Policy, Kyonghoon Kim Jan 2016

Three Essays On The Global Financial Crisis And Fiscal Policy, Kyonghoon Kim

Legacy Theses & Dissertations (2009 - 2024)

In the first chapter, I show that external openness factors and valuation effects are significant to explain the diverse impact of the Global Financial Crisis across countries. Unlike previous crises in the late 20th century, most developing country groups performed better than advanced countries during the GFC. I find that countries with higher trade and financial openness are more seriously damaged from the external shock during the GFC. Moreover, significant differences in the composition of countries’ external portfolio contribute to the variety of the crisis impact. Emerging countries which have short position in equity and long position in bond are …


Investigation Into The Function Of Endothelial Cells And Their Signaling In Early Salivary Gland Development, Hae Ryong Kwon Jan 2016

Investigation Into The Function Of Endothelial Cells And Their Signaling In Early Salivary Gland Development, Hae Ryong Kwon

Legacy Theses & Dissertations (2009 - 2024)

Functional vasculature regulates organ formation and regeneration. Perfusion-independent and nutrition-independent endothelial regulation of epithelial patterning is of considerable interest for application in restoring parenchymal function. During murine submandibular salivary gland development, the vasculature co-develops with the epithelium; however, it is still unknown if the vasculature has instructive effects on the epithelium. A systems biological study revealed that endothelial genes are enriched in epithelial clefts, suggesting a potential involvement of endothelial cells in early morphogenesis. Using immunodepletion of the endothelial cells from the mesenchyme of reconstituted glands, a requirement for endothelial cells in epithelial patterning was demonstrated. Specifically, lobule formation was …


Antibody-Mediated Immunity To Vibrio Cholerae At Epithelial Surfaces, Kara Jeanette Levinson Jan 2016

Antibody-Mediated Immunity To Vibrio Cholerae At Epithelial Surfaces, Kara Jeanette Levinson

Legacy Theses & Dissertations (2009 - 2024)

Vibrio cholerae, the causative agent of the severe diarrheal disease cholera, has an estimated worldwide disease burden in the millions and remains a significant public health threat. Immunity to V. cholerae is primarily antibody-mediated and though V. cholerae colonization evokes a mucosal immune response, it is the secretory IgA (SIgA) antibodies produced against bacterial surface antigens, specifically lipopolysaccharide (LPS) that confer protective immunity. SIgA antibodies are thought to function by inhibiting colonization by cross-linking and agglutination of pathogens, thereby limiting access to the epithelium, a process known as immune exclusion. Recent studies in other enteric pathogens have demonstrated that SIgA …


The Developmental Corporative State : How Government Promotes Innovation Capability In China, Tianyue Ma Jan 2016

The Developmental Corporative State : How Government Promotes Innovation Capability In China, Tianyue Ma

Legacy Theses & Dissertations (2009 - 2024)

This dissertation examines the question how Chinese government breaks structural constraints of the communist past and gradually reforms institutions into an innovation oriented system. Based on the study of Zhongguancun science park and also three other development zones in China, I argue that state plays a significant role in commercializing research results and upgrading Chinese indigenous technologies. Different from the already identified development models, Chinese state takes another path—what I call the Developmental Corporative State, with the central government steering the general directions while giving local governments the autonomy to flexibly implementing central policies and taking initiatives in institutional reform. …


The Social And Emotional Learning And Character Education Of K-12 Online Students : Teacher Perspectives, Anna Warwick Nolan Jan 2016

The Social And Emotional Learning And Character Education Of K-12 Online Students : Teacher Perspectives, Anna Warwick Nolan

Legacy Theses & Dissertations (2009 - 2024)

ABSTRACT


Persuasion In Online Communication : Automation And Counteraction, Samira Shaikh Shaikh Jan 2016

Persuasion In Online Communication : Automation And Counteraction, Samira Shaikh Shaikh

Legacy Theses & Dissertations (2009 - 2024)

In this thesis, we studied persuasion in online communication and how to automate


The Creation Of The Self And The Birth Of Inequality : Locke And Rousseau On Natural Rights And Private Property, Michael Sokoler Jan 2016

The Creation Of The Self And The Birth Of Inequality : Locke And Rousseau On Natural Rights And Private Property, Michael Sokoler

Legacy Theses & Dissertations (2009 - 2024)

The formation of civil societies marked one of the most monumental shifts


Exploring The Association Between Perceived Safety Of Household Children In The Neigborhood And Levels Of Depressive Symptoms Among Spanish Speaking Latina Adults Living In A High Crime, Low Income Neigbhorhood, Randall Stetson Jan 2016

Exploring The Association Between Perceived Safety Of Household Children In The Neigborhood And Levels Of Depressive Symptoms Among Spanish Speaking Latina Adults Living In A High Crime, Low Income Neigbhorhood, Randall Stetson

Legacy Theses & Dissertations (2009 - 2024)

Previous research has confirmed that neighborhood level social factors (e.g. crime, safety) present chronic stressors that increase risk for depression in residents of economically disadvantaged neighborhoods. U.S. Latinos experience higher levels of poverty and thus are more likely to live in poor neighborhoods. In this study it was hypothesized that adult Latina women who reported (1) higher levels of worry regarding the general safety of their household children in the neighborhood, (2) higher levels of worry regarding influence of bad friends on their household children, and (3) higher levels of worry regarding their household children being exposed to drugs and …


Low-Level Arsenic Exposure Via Drinking Water And Female Fecundity, Michele L. Susko Jan 2016

Low-Level Arsenic Exposure Via Drinking Water And Female Fecundity, Michele L. Susko

Legacy Theses & Dissertations (2009 - 2024)

Abstract


Do Differentiation Of Self And Dispositional Optimism Moderate The Relation Of Perceived Ptsd Symptoms To Military Partners' Romantic Relationship Satisfaction?, Patricia Cabrera Jan 2016

Do Differentiation Of Self And Dispositional Optimism Moderate The Relation Of Perceived Ptsd Symptoms To Military Partners' Romantic Relationship Satisfaction?, Patricia Cabrera

Legacy Theses & Dissertations (2009 - 2024)

Despite extensive research on the harmful effect of posttraumatic stress disorder (PTSD) symptoms on veterans, little is known about military couples’ post-deployment adjustment process. From the perspective of positive psychology, the present study extended the literature on this topic by examining the possible buffering contributions of dispositional optimism and differentiation of self on the relation between partner-perceived PTSD symptoms and relationship satisfaction.


Jakaltek Identity And The Fiesta Maya In Jupiter, Florida : Ethnic Belonging, Community, And Home, Maria M. Diaz Montejo Jan 2016

Jakaltek Identity And The Fiesta Maya In Jupiter, Florida : Ethnic Belonging, Community, And Home, Maria M. Diaz Montejo

Legacy Theses & Dissertations (2009 - 2024)

As immigration increasingly becomes a divisive issue in US politics and political measures are implemented to ensure safe borders, immigrants must find ways to avoid deportation. They must also find ways to support each other and maintain a sense of identity as their presence in the USA continues to be challenged and threatened. My research on Jakaltek migrants in Jupiter, Florida concentrates on Jakaltek migrant reconceptualization of home at the same time that they engage in identity politics that challenge a singular understanding of ethnic belonging. How Jakalteks react to their experiences in Jupiter as (mostly undocumented) migrants suggests that …


Application Of Cotter And Colleagues' Glass Ceiling Test To Examine Salary Disparity In Field Of Social Work, Kris Foote Jan 2016

Application Of Cotter And Colleagues' Glass Ceiling Test To Examine Salary Disparity In Field Of Social Work, Kris Foote

Legacy Theses & Dissertations (2009 - 2024)

Abstract


Prisons And Power : Carceral Coloniality In Hybrid Post-Neoliberal Venezuela, Cory Fischer-Hoffman Jan 2016

Prisons And Power : Carceral Coloniality In Hybrid Post-Neoliberal Venezuela, Cory Fischer-Hoffman

Legacy Theses & Dissertations (2009 - 2024)

This dissertation examines contemporary Venezuela’s dual prison system--in which half of the prison population is incarcerated in internally controlled prisons run by armed inmates, and the other half are locked up in the Bolivarian Government’s restricted “New Regime” prisons. The Venezuelan state formation is conceptualized as ‘hybrid post-neoliberal,’ demonstrating how rationalities of a liberal rentier state and neoliberalism, combined with anti-neoliberal logics all act together in competing yet co-existing ways in the post-neoliberal era, which was initiated by the 1999 Bolivarian Revolution. The central question examines the “work” of the prison in the (re)production of power relations and how policies, …


Evaluating The Immediate Impacts Of Brief Mindfulness Versus Lovingkindness Meditation, Jamie Rae Forsyth Jan 2016

Evaluating The Immediate Impacts Of Brief Mindfulness Versus Lovingkindness Meditation, Jamie Rae Forsyth

Legacy Theses & Dissertations (2009 - 2024)

Although meditation has been around for centuries, it’s only recently that the utility of such an ancient practice has gained popularity within Western psychology. A vast body of literature supports the notion that meditation can have important impacts on suffering and psychopathology; however, few studies have evaluated differential effects between various forms of meditation. The aims of this study are threefold: 1) to determine if a brief meditation can have immediate effects on an individuals’ mood, 2) to determine the validity of two different types of meditations (mindfulness and lovingkindness) and 3) to evaluate the differential efficacy of the two …


Bayesian Model Testing Of Models For Ellipsoidal Variation On Stars Due To Hot Jupiters, Anthony Gai Jan 2016

Bayesian Model Testing Of Models For Ellipsoidal Variation On Stars Due To Hot Jupiters, Anthony Gai

Legacy Theses & Dissertations (2009 - 2024)

A massive planet closely orbiting its host star creates tidal forces that distort the typically spherical stellar surface. These distortions, known as ellipsoidal variations, result in variations in the photometric flux emitted by the star, which can be detected by the Kepler Space Telescope. Currently, there exist several models describing such variations and their effect on the photometric fux [1] [2] [3] [4]. By using Bayesian model testing in conjunction with the Bayesian-based exoplanet characterization software package EXONEST [4] [5] [6], the most probable representation for ellipsoidal variations was determined for synthetic data and two systems with confirmed hot Jupiter …


Investigation Of Enzymatically Synthesized Glycogen As A Novel Nanodendrimer For Therapeutic Delivery, Sarah Ann Engelberth Jan 2016

Investigation Of Enzymatically Synthesized Glycogen As A Novel Nanodendrimer For Therapeutic Delivery, Sarah Ann Engelberth

Legacy Theses & Dissertations (2009 - 2024)

The field of medicinal chemistry is ever expanding, designing and discovering new therapeutic strategies. Oftentimes, it is challenging for these therapeutics to undergo clinical translation due to ineffective administration or unwanted toxicity in vivo. As such, drug delivery vehicles are designed to overcome these hurdles, allowing for delivery to the site of action by improving biodistribution, protecting therapeutic cargo, and decreasing toxicity. The work presented here aims to investigate a naturally-derived carbohydrate nanodendrimer, enzymatically synthesized glycogen (ESG) for drug delivery. This nontoxic, highly-branched, glucose-based structure has interior void volumes to allow for cargo encapsulation as well as a large density …


Poisoned Hope : Mias, Mythmaking, And Trauma In Defeated Nations, Patrick Gallagher Jan 2016

Poisoned Hope : Mias, Mythmaking, And Trauma In Defeated Nations, Patrick Gallagher

Legacy Theses & Dissertations (2009 - 2024)

This dissertation examines a postwar phenomenon that it describes as the secret camp myth. That myth arises from uncertainty about the fates of POWs and MIAs, and its advocates argue that the MIAs must survive in secret captivity after the war. This dissertation examines two historical examples of this phenomenon: West Germany following World War II, and the US after the Vietnam War. These two examples have been examined individually, but have not been compared extensively, and prior historiography has only examined each within the context of German and American histories of those wars. This dissertation argues that both cases …


Network Pruning For Scaling Dynamic Community Detection, Gaurav Ghosh Jan 2016

Network Pruning For Scaling Dynamic Community Detection, Gaurav Ghosh

Legacy Theses & Dissertations (2009 - 2024)

Local community detection is an important tool for the analysis of networks of different genres. The goal is to identify only the best communities in a network instance as opposed to computing a partitioning of the whole network. The majority of the work on local community detection has focused on static networks with less attention on networks that evolve over time. Given a trace of temporal interaction among nodes in a network, how can we detect a period of high interaction for a specific group of nodes? To help temporal community detection with the need to search in the time …


The Network Average Gust Factor, Its Measurement And Environmental Controls, And Role In Gust Forecasting, Alexander Austin Gallagher Jan 2016

The Network Average Gust Factor, Its Measurement And Environmental Controls, And Role In Gust Forecasting, Alexander Austin Gallagher

Legacy Theses & Dissertations (2009 - 2024)

There exists a strong, well documented linear relationship between network averaged sustained (or mean) wind and gust speeds within the San Diego Gas and Electric (SDGE) mesonet that is characterized by the slope of the linear regression between the two known as the network average gust factor (GF). The network average GF potentially contains information on the average obstruction of the stations within the network and when paired with numerical model output, may be used for gust prediction. Using the network average GF for gust prediction can also result in the correction of biases due to poorly resolved terrain or …


Predictive Validity Of Curriculum-Based Reading Measures For High-Stakes Outcome Assessments With Secondary Students Identified As Struggling Readers, Tierney Gifford Jan 2016

Predictive Validity Of Curriculum-Based Reading Measures For High-Stakes Outcome Assessments With Secondary Students Identified As Struggling Readers, Tierney Gifford

Legacy Theses & Dissertations (2009 - 2024)

Curriculum-based measurement (CBM) tools are used widely to assess students’ progress within different stages of the Response to Intervention (RTI) process. Despite the wide-spread use, little research has identified the efficacy of reading CBMs in predicting secondary student outcomes on high-stakes assessments. High-stakes assessments are being utilized to determine outcomes for not just students, but teachers, administrators, and districts. More research is needed to determine if reading CBMs are useful tools for the populations of struggling secondary readers. The current study was a secondary analysis of existing data, which attempted to gain an understanding of this through examining the predictive …


Degradation And Exciton Energy Transfer Studies In Single-Walled Carbon Nanotube Bundles, Abhishek Gottipati Jan 2016

Degradation And Exciton Energy Transfer Studies In Single-Walled Carbon Nanotube Bundles, Abhishek Gottipati

Legacy Theses & Dissertations (2009 - 2024)

Single walled carbon nanotubes (SWNTs) due to their unique optical behavior, large surface area, robust mechanical strength and electrical properties make them one of the ideal candidates for sensing and opto-electronic applications. In this work, we explore the energy transfer (exciton energy transfer-EET) phenomena occurring between nanotubes in bundles, using resonance Raman spectroscopy.


Development Of Low-Temperature Atomic Layer Deposition Of Ultra-Thin Ruco Direct Plate Liners For Flexible Electronics Applications, Dillon Alexander Gregory Jan 2016

Development Of Low-Temperature Atomic Layer Deposition Of Ultra-Thin Ruco Direct Plate Liners For Flexible Electronics Applications, Dillon Alexander Gregory

Legacy Theses & Dissertations (2009 - 2024)

Low temperature plasma-assisted atomic layer deposition-grown metal nanocomposite layers based on mixtures of ruthenium and cobalt have been investigated as potential copper adhesion/barrier layers in flexible electronics applications. The success of adapting this process to flexible electronics depends on the candidate barriers meeting several necessary properties including sufficient electrical conductivity, compatibility with Cu electroplating, and ability to prevent Cu diffusion into the substrate. Preliminary testing has shown that atomic layer deposition (ALD) can be used as a technique for depositing alloyed metallic barrier layers at the lower thermal constraints dictated by the use of polymer substrates and still produce continuous …


Event Risk : Three Essays Exploring Nonprofit Organizations' Finances After The September 11 Attacks, Santiago Guerrero Jan 2016

Event Risk : Three Essays Exploring Nonprofit Organizations' Finances After The September 11 Attacks, Santiago Guerrero

Legacy Theses & Dissertations (2009 - 2024)

The three essays of this dissertation explore the experience of nonprofit organizations after the September 11 attacks to gain a better understanding of one specific type of risk nonprofit organizations face— “event risk” — which I broadly define as the risk of a negative impact on the operations of a nonprofit organization as a result of unexpected events. Essay One finds that overall nonprofit sector revenues were not reduced after the September 11 attacks and identifies characteristics of the revenue mix that make nonprofit organizations less susceptible to event risk. Essay Two identifies characteristics of nonprofit organizations’ financial conditions that …


Topic Modeling For E-Petition Analysis : Interpreting Petitioners' Policy Priorities, Loni Hagen Jan 2016

Topic Modeling For E-Petition Analysis : Interpreting Petitioners' Policy Priorities, Loni Hagen

Legacy Theses & Dissertations (2009 - 2024)

The Obama Administration launched an e-petitioning site called “We the People” (WtP) in 2011 to encourage the submission of citizens’ policy suggestions. Since 2011, thousands of petitions have been submitted to this site. Analysis of the contents of petition texts using topic modeling may enable policy makers and government leaders to identify latent topics of public interest that are not otherwise apparent.