Digital Commons Network^™

Mortal Rivers: A Case Study Analysis Of Indigenous Water Sovereignty Within The Penobscot And Lakota Nations, 19th Century To Present, Moya S. Stringer

Honors Theses

Indigenous water sovereignty has long been a contested problem within the continent of Turtle Island. In 2016, the Lakota Nation globalized the message Water is Life through their movement against the Dakota Access Pipeline, an oil infrastructure that would put one of the continent’s largest watersheds at risk. The revolutionary fervor of the Water is Life movement travelled all the way to the Penobscot Nation in the Dawnland, a place we now call Maine. In an adjacent vein to the Lakota, the Penobscot people have spent the 21st century addressing damming projects and rampant pollution from the 1900s in a …

"It’S Just Another Thing”: Perceptions Of Well Water Quality And Barriers In An Arsenic Hot Spot, Linzy Rosen

Honors Theses

Privately owned water is the primary source of drinking water for 43 million Americans. Although residential or private wells are susceptible to a variety of contaminants, the Safe Drinking Water Act of 1974 positions individuals as responsible for the testing, remediation, and management of this water. Despite the elevated presence of arsenic in Maine, which is linked to various cancers, cardiovascular disease, and neurological damage, little is known about how private well owners perceive the safety and quality of their own water.

This study takes a qualitative approach to understanding concerns and opinions by conducting semi - structured interviews with …

The Effects Of Nutrient Limitation On Toxin Production For The Harmful Algal Bloom Species, Pseudo-Nitzschia, In The Gulf Of Maine, Julia M. Park

Honors Theses

Pseudo-nitzschia is a pennate marine diatom that produces the neurotoxin domoic acid (DA). Domoic acid accumulates in the digestive tract of filter feeders and becomes concentrated at higher trophic levels. When DA concentrations reach critical levels, consumption of toxic shellfish can induce a condition known as Amnesic Shellfish Poisoning (ASP), which has been responsible for the deaths of marine mammals, seabirds and humans. This study worked to respond to a toxic Pseudo-nitzschia bloom in the Gulf of Maine during the fall of 2016, with the goal of quantifying and identifying Pseudo-nitzschia spp. in the bloom region and to determine the …

The Effect Of Glutamate On Neurite Outgrowth In Fiddler Crab (Uca Pugilator) X-Organ Cells, Ruth B. Langton

Honors Theses

Glutamate is the primary excitatory neurotransmitter in the mammalian central nervous system. It is of particular interest because of its supposed role in the processes of learning and memory, and also because of its potential toxic effects that have been linked to neurodegenerative diseases, such as Alzheimer’s and Parkinson’s. Although glutamate is necessary for normal cell functioning, high levels of glutamate receptor activation can result in cell death, a phenomenon known as excitotoxicity. It has been suggested that glutamate also plays an important role in the insect and crustacean nervous systems, allowing for the examination of excitotoxicity in these organisms. …

Learning The Lay Of Their Land: Data Recording By Maine Land Trusts, Patrick John Roche

Honors Theses

Land trusts have led the recent, rapid expansion in private land conservation in the US. As they have grown, many questions have emerged as to the value of their conservation efforts, especially in the long-term. To address this data gap, studies have evaluated easement restrictions and the characteristics of land trust protected property. I take a novel approach by investigating the data that land trusts record about their protected properties and its impact on their capacity to protect conservation values. I surveyed 55 land trusts operating in Maine about data they record in baseline documentation reports. A majority (82%) had …

Cisplatin Interstrand Cross-Linking Of Defined Sequence Nucleosomal Dna, Erin Elizabeth Wilkes

Honors Theses

DNA interstrand cross-linking agents have been recognized for many years to be powerful antitumor chemotherapeutics. While the interactions between free DNA and many anticancer drugs have been explored extensively, there is less infonnation available about these interactions with nucleosomal DNA. Nitrogen mustards have been reported to exhibit relatively similar cross-linking sites and efficiencies of binding in free and nucleosomal DNA, but mitomycin C exhibits markedly reduced cross-linking near the center of nucleosomal DNA. This current study focuses on cisplatin interstrand cross-linking of the 154 base pair 55 rRNA gene fragment of Xenopus borealis reconstituted with histones from chicken erythrocytes. The …