Digital Commons Network^™

Reflecting On Psychotherapy In Adolescence: A Qualitative Analysis Of Processes Of Change, John Parigger

Electronic Theses and Dissertations

There is a sharp increase in anxiety and depression symptoms in adolescence, and many forms of psychotherapy are shown to be effective. However, most research has examined average effects for manualized treatments that address multiple areas of functioning, which makes it difficult to determine how psychotherapy causes positive change. Process-based therapy postulates that all psychotherapies work through promoting adaptive biopsychosocial patterns of behavior (i.e., processes of change). Research has increasingly focused on the process-based therapy model, and there is a need for qualitative studies to incorporate lived experience into our understanding of change processes. The current study utilized the process-based …

Kinesiology Department Chairs’ Perceptions Of Their Training And Preparation, Kason O’Neil

Electronic Theses and Dissertations

Department chairs are responsible for leading academic departments in higher education.  These individuals regularly make important decisions regarding such things as managing faculty and academic programming, overseeing budgets, and supporting student needs. Despite these responsibilities, many people become department chairs without receiving formal leadership training. This study explored how kinesiology department chairs across the United States viewed their preparation for the role and the importance of leadership training. A total of 111 department chairs completed an online survey about their background, previous training, and the importance of training for different administrative responsibilities. The results showed that most chairs had little …

Weathering The Divide: Social Determinants, Neighborhood Context, And Systemic Lupus Erythematosus Among African American Women, Vanessa Cl Morman

Electronic Theses and Dissertations

Background: Systemic lupus erythematosus (SLE) disproportionately affects African American women and contributes to racial health disparities in the United States. Although genetic susceptibility influences disease risk, growing evidence suggests that social determinants of health (SDOH), including neighborhood conditions, structural racism, and socioeconomic disadvantage, contribute to disease development and progression. Epigenetic mechanisms may provide a biological pathway linking adverse social conditions to chronic disease disparities. This dissertation examined the influence of SDOH on SLE disparities through evidence synthesis and empirical investigation to inform public health practice and policy.

Methods: This integrated learning experience consisted of three complementary manuscripts. Aim 1 was …

Leveraging Mammal Mycophagy To Determine Environmental Drivers Of Truffle Diversity, Brittany Hartsock

Electronic Theses and Dissertations

Many mycorrhizal fungi are hypogeous (truffle-forming), producing underground fruiting bodies. Studying truffles is inherently challenging due to their hidden nature. However, mycophagous mammals provide a unique opportunity to study hypogeous fungi because they rely on truffles as a food source. Although several truffle species have recently been described in the southern Appalachian region, their fruiting patterns remain poorly understood. To address this, we quantified truffle richness and spore loads from 670 Peromyscus scat samples collected across 42 sites spanning an environmental gradient during 2024 in the Blue Ridge Mountains of East Tennessee. We found that truffle richness and spore abundance …

Exploring Competitive Dynamics Between Pseudomonas Baetica And Salmonella In A Polymicrobial System, Braxton E.M. Stout

Electronic Theses and Dissertations

The global rise in antimicrobial resistance has catalyzed a greater focus on polymicrobial research aimed at characterizing microbial interactions and uncovering new therapeutic strategies. Though it has long been of interest, environmental soil-derived bacteria remain largely under-represented in research and thus uncharacterized in this field. This project aimed to identify soil microbes that display inhibitory mechanisms to potential nosocomial pathogens. Soil sample S1S3-2 displayed inhibitory phenotypes toward numerous bacteria and was identified as Pseudomonas baetica. In both planktonic and biofilm growth, P. baetica was able to inhibit Salmonella arizonae through a contact-dependent and temperature-dependent manner. Screening of a transposon insertion …

Phytochemical And In-Vitro Cytotoxic Analyses Of Flavonoid Species Isolated From Chromolaena Leivensis, Luke A. Bryant

Electronic Theses and Dissertations

As a leading cause of death worldwide, cancer and its treatments remain a primary source of interest among researchers. Modern studies are looking into bioselective cytotoxicity to create new chemotherapies that do not have the same harsh side effects as those we use today. Natural product research has a promising future for the development of such treatments. Specifically, polar flavonoids may be the key to a bioselective treatment. Such flavonoid species are native to plants, often within flower petals or within the body. A natural antioxidant, they are designed not to harm healthy cells. This study focuses on the plant …

Barriers To Veterans Affairs (Va) Healthcare Utilization: Exploring The Underutilization Of Va Healthcare Services Among Rural, West Texas Veterans, Adam G. Rodgers

Electronic Theses and Dissertations

Rural veterans forgo Department of Veterans Affairs (VA) healthcare at disproportionate rates, and this study found that the primary barrier is not enrollment but utilization. Seven of the eight participants were already enrolled yet remained functionally outside the system. The purpose of this qualitative single-case study was to explore why rural West Texas veterans forgo and underutilize Veterans Health Administration (VHA) healthcare. Two research questions examined the perceptions contributing to that decision and the barriers preventing access. Andersen’s behavioral model of health services use provided the framework. Semistructured virtual interviews with eight rural West Texas veterans were analyzed using Braun …

Enterococcus Abundance, Distribution, And Environmental Controls At A Sandy Shoreline, South Carolina, Usa, Helen Kehoe

Electronic Theses and Dissertations

Water quality monitoring crucially protects the health of beachgoers around the world. However, water-adjacent sediments, such as sandy beaches, are known to harbor harmful bacteria, yet are not monitored despite their intensive recreational use. This project monitored the abundance of fecal indicator bacteria (FIB), specifically Enterococci, in sandy beach sediments at beaches routinely monitored for water quality in Myrtle Beach and North Myrtle Beach, South Carolina. Surface sediment core sampling (0-5 cm) in the swash zone was conducted once per month for 4 months at 24 beaches in tandem with state-accredited surf-water FIB monitoring using IDEXX’s Enterolert test (Standard Method …

Comparison Of River Plume Classification Methods Using In-Situ Data, Payton Merica

Electronic Theses and Dissertations

River plumes transport terrigenous materials into the ocean, such as nutrients, pollutants, or sediment. These plumes can be separated into regions, including the source region, near-field, mid-field, and far-field, historically defined broadly by the governing forces in each region. Existing methods for classifying these plume regions are limited and often only take into account a subset of influencing factors. This study seeks to compare prior plume region classification methods, such as the Froude number and Rossby radius of deformation, to dominant dynamics within each region using momentum scaling proposed by Garvine (1995). Comparisons were derived from observational data collected during …

Long-Term Trends And Drivers Of Commercial Shrimp Fisheries Across The Southeastern U.S. Atlantic Coast, Trinity Assels

Electronic Theses and Dissertations

Long-term dynamics of southeastern U.S. Atlantic commercial shrimp fisheries reflect interacting environmental and socioeconomic processes rather than uniform regional decline. However, integrated, multi-state assessments linking these drivers to fishery-dependent indicators remain limited for the region. This study analyzed over four decades (1980–2023) of confidential fishery-dependent data from coastal South Carolina, Georgia, and northeastern Florida, focusing on the region where white and brown shrimp dominate commercial landings. Segmented regression analysis was used to identify structural shifts in long-term trends of landings, participation, and catch-per-unit-effort (CPUE), while multiple linear regression models identified seasonal temperature variables associated with interannual variation in shrimp CPUE. …

Presence And Impact Of Herbicides On Intertidal Benthic Communities, Marco Sanderson

Electronic Theses and Dissertations

The growing reliance and widespread use of herbicides on a global scale is negatively affecting non-targeted biota and, consequently, their ecosystems. Herbicide levels and their impacts have been extensively researched around the world in riverine and lacustrine ecosystems. However, studies of the levels and effects of herbicides on coastal intertidal benthic communities have been lacking. This study focused on testing spectrophotometric methodologies for herbicides (atrazine and glyphosate) and documenting their presence and levels in sediment, water, and biotic tissue of intertidal coastal beaches and marshes of Waties Island and Singleton Swash, Horry County, South Carolina. A laboratory microcosm was employed …

Trophic Ecology Of A South Carolina Estuarine Predator Guild, Shane John Molander

Electronic Theses and Dissertations

Estuaries are among the world’s most productive ecosystems in the world and are characterized by the convergence of two distinct habitats, creating a mosaic of environmental conditions from inland rivers to the nearshore ocean. Many fishes occupy estuaries during various life stages for growth, reproduction, or foraging, and may reside in them seasonally. The co-occurrence of species, particularly upper-trophic level carnivores, can result in competitive interactions for prey resources within a shared environment. Identifying the degree of these interactions as well as understanding basal energy consumption can inform food web dynamics and how overlapping species use shared spaces. I used …

Toward Design-To-Fabrication Continuum For Open-Source Computational Robotic Ecologies In The Post-Anthropogenic Era, Celso Urroz

Electronic Theses and Dissertations

Computational design and robotic fabrication have expanded architecture’s capacity to coordinate geometry, material behavior, machine operation, and environmental performance. Yet many design-to-fabrication workflows remain structured by industrial logics of separation, standardization, and control. Design is often abstracted from material execution, fabrication is treated as a downstream phase, and robotic systems remain concentrated within specialized or proprietary infrastructures. This dissertation addresses this problem by proposing the design-to-fabrication continuum as an open, transferable, and ecologically situated framework in which computation mediates among design intent, matter, machine, environment, and shared technical knowledge.

The research uses a practice-based methodology combining computational workflow development, material …

Synthesis, Utilization And Biological Evaluation Of Β-Hairpin Peptides As Inhibitors Of Immune Checkpoints, Sarah Naylon

Electronic Theses and Dissertations

Peptide therapeutics have emerged as promising alternatives to monoclonal antibodies because of their smaller size, improved tissue penetration, and synthetic versatility. Yet their broader application is often limited by poor structural stability, rapid clearance, and reduced target residence times. This dissertation describes the design, synthesis, structural characterization, and biological evaluation of β-hairpin peptides as inhibitors of immune checkpoints and as peptide vaccine scaffolds while developing strategies to overcome these limitations. At first a series of antibody-derived β-hairpin peptides (mimics of complementary determining region heavy-chain 3: CDR-H3s) as covalent inhibitors of the PD-1/PD-L1 immune checkpoint were investigated. Electrophilic warheads were incorporated …

Mystical Revelation And Knowledge Of God: Reclaiming Spirituality In Theology Through The Mystics, Elizabeth A. Merski

Electronic Theses and Dissertations

Since the scholastic era, the pursuit of God has occurred preeminently through reason, leading to an imbalanced theology of God that persists to the present day in the form of intellect-centered theology. As a resolution, this work proposes that the mobilization of private, mystical revelation as a source of legitimized theological knowledge of God has the potential to close the existent epistemological gap between reason/belief and theology/spirituality, demonstrating the integral unity between authentic knowledge of God and the receiver’s personal acceptance of God in faith. After examining the required methodological components for the discipline of theology and identifying criteria for …

Development Of Minimalist Trifunctional Building Blocks For Chemical Biology Probe Synthesis, Luke E. Bohrer

Electronic Theses and Dissertations

The completion of the Human Genome Project in 2003 generated expectations that genomic information would accelerate the discovery of new protein drug targets and FDA-approved therapies. However, many small-molecule drug candidates continue to fail in clinical trials, and much of the human proteome remains undercharacterized in terms of structure, function, and disease relevance. Chemical tools are therefore essential for defining protein function, mapping protein interactions, and identifying disease-associated molecular mechanisms. Among these tools, small-molecule chemical probes provide a powerful strategy for connecting biological activity with target identification, functional analysis, and the development of effective therapies.

This dissertation describes the development …

Impact Of Taped Problems Intervention Modification On Children With Deafness, Clyniece Hodge

Electronic Theses and Dissertations

Children with hearing loss are at an increased risk of experiencing setbacks in various areas of life, including academic performance and employment opportunities. Academically, they are likely to experience poor academic achievement in reading, as well as in mathematics (ASHA, 2013). In comparison to gifted hearing students and average-ability hearing students, students with hearing loss are at a higher risk of low mathematics performance (Hassan & Mohammed, 2019). Despite these known challenges and risk factors, limited research has been conducted to identify effective intervention strategies for improving mathematical outcomes among this population. As such, this study aimed to evaluate the …

Integrating Naturalistic Developmental Behavioral Interventions In Inclusive Classrooms To Support Autistic Students, Paige J. Johnson

Electronic Theses and Dissertations

The current trend of an increasing prevalence rate of autism spectrum disorder creates a growing need for evidence-based interventions that can be accessed in the natural environments, such as within inclusive educational settings. Naturalistic Developmental Behavioral Interventions (NDBIs) integrate principles of applied behavior analysis and developmental psychology, and offer effective tools for increasing social communication behaviors in autistic children that align with the neurodiversity-affirming movement. The present study sought to evaluate the effectiveness of Behavior Skills Training (BST) in teaching core NDBI skills to a preschool teacher, examine changes in teacher self-efficacy related to supporting autistic students, and assess the …

A Mixed-Methods Pilot Study Of A 10-Week Wellness Program For Resident Assistants, Emily L. Lee-Chong

Electronic Theses and Dissertations

This mixed-methods pilot study used semi-structured interviews with 15 resident assistants (RAs), complemented by descriptive pre- and post-test data from the Five Factor Wellness Inventory (FFWEL), to explore their lived experiences of participating in a 10-week wellness program grounded in the Indivisible Self Model of Wellness (IS-WEL). The purpose of this study was to examine the program's perceived influence on wellness practices and to explore the feasibility of implementing wellness-focused programming. Using a hermeneutic inquiry approach, the study identified four themes reflecting participants’ experiences throughout the program. Themes highlighted the importance of self-awareness through the IS-WEL model, the value of …

Race And Trauma: An Analysis Of Trauma Symptomology Across Diverse Youth Populations, Mara J. Niccoli

Electronic Theses and Dissertations

The adverse effects of trauma, particularly among youth who identify as Black, is a critical issue. This study investigated the relationship between race and trauma symptomology among children and adolescents who received weekly trauma therapy. With the use of clinical assessment data, this study sought to determine whether Black youth presented to treatment with higher trauma acuity than non-Black youth and if there were disparate outcomes in symptomology after treatment. The results indicated that on average, Black youth presented to treatment with lower trauma acuity than non-Black youth, and there were disparate outcomes in trauma symptomology between the two racial …

Between Care And Despair: An Existential Phenomenological Study Of Eco-Anxiety As Lived Experience, Conor H. Sukhdeo

Electronic Theses and Dissertations

This dissertation explores the lived experience of eco-anxiety among young adults aware of the ongoing ecological crisis but not directly exposed to climate-related disasters. Grounded in the human science tradition, ecopsychology, and existential phenomenology, this study employed Scott Churchill’s (2022) approach to Existential Phenomenological Research (EPR) to deepen our understanding of the phenomenon of eco-anxiety. Four participants, residing in Pittsburgh and aged 18-25, produced written experiential descriptions and participated in open-ended phenomenological interviews. As outlined by EPR, this data was analyzed through meaning unit delineation, imaginative variation, phenomenological reduction, and structural synthesis to produce individual situated structures of eco-anxiety for …

The Narrative In The Algorithm: Storytelling, World Literature, And The Smartphone, Chad Szalkowski-Ference

Electronic Theses and Dissertations

In this dissertation, I interrogate the role algorithms, artificial intelligence, and smartphone technology play in contemporary world literature. My analysis begins with the post-truth condition, which speaks to the contemporary era’s embrace of alternative facts, authoritarianism, and conspiratorial thinking. I draw on narrative theory and paradigms of world literature to show how “algorithmic reasoning” has led to a state of paranoid persecution. This reasoning has forged new collectivities across traditional borders. Additionally, I show that these new collectivities and new technologies have produced new narrative points of view: the algorithmic first- and third-person, allowing narratives to retain the intimacy and …

Algebraic And Topological Methods In Computational Neuroscience, Trong-Thuc Trang

Electronic Theses and Dissertations

Neural data is incredibly rich in combinatorial, topological, and geometrical information, reflecting the intricate shape and connectivity of neural firing patterns. To decipher these structures, neuroscience increasingly relies on advanced mathematical tools to analyze neural activity. Here we study (1) neural codes within the poset P_Code of neural codes and (2) the connectivity of neural population activity within the insular cortex when responding to interoceptive information. In (1), we establish combinatorial constructions for all upward covering relations based on what we call “isolated subsets” with supporting theorems and give a slight modification of the existing downward covering relations. We …

Changes In Water Quality And Microbiota Over Two Years In Florida Hard Clam (Mercenaria Mercenaria) Hatcheries, Bonnie Getter

Electronic Theses and Dissertations

This thesis characterized the water quality and bacterial communities in nine hard clam hatcheries over two production years through weekly or biweekly water quality and chemistry monitoring, monthly bacterial plating in the second year of production, and select 16S microbiome sampling at select hatcheries to address production bottlenecks and support the reliable production of high-quality seed for Florida’s growing hard clam aquaculture industry. Logistic regression models showed that water source was distinguished by pH, salinity, alkalinity, and nitrite, whereas geographic location was distinguished by temperature, salinity, nitrate, and calcium; temperature, dissolved oxygen, salinity, and alkalinity distinguished seasons. Vibrio bacteria differed …

Contributions Of Arginine And Nitrosative Stress To Huntington’S Disease Progression, Ian D. Gaudet

Electronic Theses and Dissertations

Neuroinflammation is a well-established component of Huntington's disease (HD) pathogenesis, yet the intricate molecular mechanisms that govern this process remain a topic of ongoing research and debate. This dissertation elucidates a novel pathway linking arginine metabolism and nitrosative stress to core HD pathology. We found that the arginine transporter SLC7A2 is selectively upregulated in various HD cellular models and patient samples. Our findings reveal that this upregulation drives an overactive inflammatory response, leading to abnormally high inducible nitric oxide synthase (iNOS) induction and subsequent nitric oxide (NO) production, which causes excessive protein nitrosylation and an increase in mitochondrial fragmentation.

To …

Educator Experiences Of Schoolwide Pbis Discipline Implementation: Exploring School Culture In Private Pk–12 Schools, Jessica L. Guarneri

Electronic Theses and Dissertations

The purpose of this phenomenological study was to explore educators’ lived experiences implementing schoolwide Positive Behavioral Interventions and Supports (PBIS) discipline systems and to understand how those experiences influenced school culture in private PK–12 schools. Historically, PBIS focused on specific outcomes, such as reductions in discipline referrals, suspensions, and behavioral incidents. Though these indicators are critical, they do not consider in what way educators experience disciplinary systems, nor how their lived experiences affect routine interactions with students. Educators play a key role in implementing PBIS; their experiences foster consistency, trust, and sustainability. The participants included certified educators and administrators employed …

A Qualitative Examination Of Tennessee Secondary Stem Teachers’ Perceptions On Professional Development Needs, Amber W. Ogle

Electronic Theses and Dissertations

The purpose of this qualitative phenomenological study was to research secondary STEM educators’ perceptions of PD needs. This study focused on the lived experiences of educators actively teaching in STEM subject disciplines in grades nine through 12. The essential question for this research study was: How do Tennessee secondary STEM teachers perceive the relevance, applicability, and impact of PD opportunities? The research was rooted in Knowles’ (1984) theory of adult learning, Andragogy, and Learning Forward’s (2022) Standards for Professional Learning.

Data were collected through 15 semi-structured, one-on-one online interviews. The transcripts of these interviews were analyzed, and frequently used language …

Developing Solvent Tolerant Microbial Membranes: Lipid Extraction And Laurdan Fluorescence Approaches For Biofuel Optimization, Gladstone Anku

Electronic Theses and Dissertations

The high demand for sustainable energy has increased interest in advanced biofuels, though production is limited by solvent toxicity to microbial hosts. This study investigated the role of lipid composition in modulating membrane fluidity and solvent tolerance using Bacillus subtilis as a model organism. Five strains were cultured, and membrane lipids were extracted and analyzed using thin-layer chromatography and gas chromatography–mass spectrometry; however, inconsistent results limited compositional characterization. To address this problem, reconstituted vesicles composed of phosphatidylglycerol (PG) and phosphatidylethanolamine (PE) were used as model membranes. Membrane fluidity was assessed using Laurdan fluorescence spectroscopy by measuring generalized polarization (GP) values …

A Large And Robust Legless Lizard (Squamata, Anguinae) From The Gray Fossil Site Of Eastern Tennessee, Justice D. Lamer

Electronic Theses and Dissertations

The early Pliocene Gray Fossil Site in Tennessee preserved an abundance of microfossils, including numerous anguid lizard specimens. This includes the following elements: dentaries, a pterygoid fragment, a jugal, frontals, parietal fragments, dorsal and caudal vertebrae, and many osteoderms. Because these specimens had not been placed taxonomically beyond the subfamily level, comparative anatomy of similar elements from extant anguids and some quantitative data were used to provide more refined identifications. Using these methods, it was determined that a new, robust type of Ophisaurus is represented at the Gray Fossil Site. Important novel features include relatively robust dentaries, fewer but broader …

Characterization Of Catechol-Type Siderophore(S) From P. Mosselii Cfml 90-83, Kemper R. Rasnake

Electronic Theses and Dissertations

Iron is essential for many biological processes, where it is used as a cofactor. Even though it is abundant in the Earth’s crust, it is in an insoluble form unavailable to microorganisms in the soil. To overcome this, bacteria produce siderophores, which are secondary metabolites that have a high affinity for iron. This allows bacterial cells to obtain insoluble iron that is essential for survival. Pseudomonas mosselii, a Gram negative bacterium, was isolated from soil. It was selected for further analysis as it was found to produce siderophore(s) under iron-limited conditions, which have not been characterized previously. Therefore, we aimed …