Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Dissertations

Discipline
Institution
Keyword
Publication Year
Publication Type

Articles 1 - 30 of 3636

Full-Text Articles in Entire DC Network

Geographic And Environmnetal Influences On Color Pattern Similarity Between Coral Snakes (Genus: Micrurus) And Their Lookalikes, Anthony Sena Aug 2026

Geographic And Environmnetal Influences On Color Pattern Similarity Between Coral Snakes (Genus: Micrurus) And Their Lookalikes, Anthony Sena

Dissertations

Venomous coral snakes and their lookalikes are often regarded as a classic example of Batesian mimicry, whereby a harmless species imitates a harmful species. The existing literature regarding coral snake resemblance presents a divisive stance on whether Batesian mimicry is the primary driver of shared color patterns or if alternative factors are responsible. While recent literature largely favors the Batesian hypothesis, empirical support remains inconsistent, and the specific geographic and interpretation of the conditions required for mimicry lacks consensus within the scientific community.

To evaluate the mechanisms maintaining these phenotypes, a quantitative, multivariate framework was utilized to analyze 400 museum …


Promoting The Bipartisan Dimension Of Political Leadership: A Study Of The Impact Of A Normative Intervention With Newly Elected Members Of Congress, Jaime M. Ruvalcaba Aug 2026

Promoting The Bipartisan Dimension Of Political Leadership: A Study Of The Impact Of A Normative Intervention With Newly Elected Members Of Congress, Jaime M. Ruvalcaba

Dissertations

The U.S. political system is more polarized now than at any time in the past century, as evidenced by the rise of political incivility, legislative gridlock, and hyperpolarization. To date, most studies and efforts have focused on institutional strategies to explain, transform, and mitigate the challenges posed to the political environment. By contrast, little attention has been paid to the normative or values-based behaviors of leaders to either explain or influence political leadership in ways that positively impact the political environment. Fortunately, some organizational programs, like Harvard’s Bipartisan Program for Newly Elected Members of Congress, have taken a different tack, …


Eusocial Caste Specialization Under Abiotic And Biotic Stress In A Stingless Bee, Tetragonisca Angustula, Kristin M. Robinson Aug 2026

Eusocial Caste Specialization Under Abiotic And Biotic Stress In A Stingless Bee, Tetragonisca Angustula, Kristin M. Robinson

Dissertations

Eusocial insects rely on division of labor to achieve high colony efficiency and provide essential ecosystem services, but specialization may also constrain colony resilience when workers operate near their physiological or behavioral limits under abiotic and biotic stressors. How specialization mediates these responses remains poorly understood, particularly in stingless bees (Tribe: Meliponini). Using the agriculturally relevant stingless bee Tetragonisca angustula, which possesses a specialized soldier subcaste, I investigated how a high degree of worker specialization influences physiological tolerance and predator responses across worker subcastes.

In this dissertation, I quantified variation in thermal tolerance and desiccation resistance among worker subcastes …


A Phenomenological Study Of The Lived Experiences Of African American Female Leaders In Public K-12 Schools In Georgia, Tyisha Davis Aug 2026

A Phenomenological Study Of The Lived Experiences Of African American Female Leaders In Public K-12 Schools In Georgia, Tyisha Davis

Dissertations

The purpose of this phenomenological study was to explore how the intersectionality of race and gender shapes the leadership experiences of African American women in public K–12 schools. Despite comprising a significant portion of the educator workforce, African American women remain underrepresented in school leadership positions nationally, warranting deeper examinations of their professional pathways and daily realities. This qualitative study employed interpretative phenomenological analysis, guided by an intersectional framework, to understand the lived experiences of 10 African American female educational leaders across K–12 settings in Georgia. Principals, assistant principals, instructional specialists, and a superintendent engaged in semi-structured interviews analyzed through …


Praise That Empowers: Training Preschool Teachers To Linguistically Adapt Behavior-Specific Praise For Hispanic Students, Claudia Abril Ochoa Aug 2026

Praise That Empowers: Training Preschool Teachers To Linguistically Adapt Behavior-Specific Praise For Hispanic Students, Claudia Abril Ochoa

Dissertations

Children’s engagement in early ages is critical for promoting behavioral, academic, and social-emotional outcomes. However, engagement in classroom activities may be difficult for young children who have not mastered the primary language used in early childhood education settings (i.e., English). Research regarding engagement in English Language Learners (ELLs) in preschool settings, as well as cultural and/or linguistic adaptations of classroom interventions to serve this population is limited. Behavior-specific praise (BSP) has been an effective strategy to improve behavior in preschool classrooms. The current study used a multiple-baseline design across three Head-Start teachers to test the efficacy of in situ training …


The Influence Of Shape Complexity And Exploratory Behavior On Grasping, Mckenzie Gunter Aug 2026

The Influence Of Shape Complexity And Exploratory Behavior On Grasping, Mckenzie Gunter

Dissertations

People can orient and configure their hands in many ways in order to grasp objects. The current study investigates how object shape and hand placement influence graspability of objects, and how experimentally imposed constraints on grasping type alter grasping behavior. In a recent study, Gunter and Hajnal (under review) found that the ratio of object curvature and maximal handspan is the variable that defines the affordance of graspability. The current study aims to extend these findings by employing a more precise measurement of finger placement in two experiments using 3D printed objects as stimuli. To capture varying complexities of object …


Listening To Fire: Using Passive Acoustic Monitoring To Detect And Explain Prescribed Fire Effects On Avian Communities In Oak-Hickory Forests Of The Central Hardwood Region, Wesley Petty Aug 2026

Listening To Fire: Using Passive Acoustic Monitoring To Detect And Explain Prescribed Fire Effects On Avian Communities In Oak-Hickory Forests Of The Central Hardwood Region, Wesley Petty

Dissertations

Prescribed fire is an increasingly important tool for restoring oak-hickory forests in the Central Hardwood Region, yet its effects on avian communities remain poorly understood because traditional monitoring methods cannot easily capture wildlife responses across the large spatial and fine temporal scales at which fire effects unfold. This dissertation develops and tests a framework for using passive acoustic monitoring (PAM) to detect prescribed fire effects on avian communities and to explain the ecological mechanisms behind them. Acoustic data were collected at Giant City State Park and Touch of Nature Environmental Center in southern Illinois across six recording sites for seven …


Love’S Dialects: Proposed Additions In Emotionally Focused Therapy For Intercultural Couples, Nicola Heurich Aug 2026

Love’S Dialects: Proposed Additions In Emotionally Focused Therapy For Intercultural Couples, Nicola Heurich

Dissertations

Intercultural romantic relationships have become an increasingly prominent feature of contemporary society due to globalization, migration, and cross-cultural exchange (Livingston & Brown, 2017). However, these partnerships are also associated with elevated levels of relational distress and higher rates of conflict, separation, and divorce, underscoring the need for culturally responsive approaches in couple therapy (Bustamante et al., 2011; Genç & Su, 2021).

Research on intercultural couples remains limited both within and beyond Emotionally Focused Therapy (EFT), and despite increased recognition of cultural factors, there is still insufficient guidance on navigating differing cultural contexts within a dyad (Linhof & Allan, 2018).

The …


Adverse Childhood Experiences And Juvenile Offending: Client-Factor Variations And A Novel Intervention Approach, Madison M. Dobreff Aug 2026

Adverse Childhood Experiences And Juvenile Offending: Client-Factor Variations And A Novel Intervention Approach, Madison M. Dobreff

Dissertations

Adverse childhood experiences have consistently been identified as risk factors for juvenile offending. However, this relationship is complex and varies based on individual factors. This critical literature review not only examined the current research on the relationship between adverse childhood experiences and juvenile offending but also identified client factor variations that influence the relationship. Client factors examined throughout include race/ethnicity, gender, age, internalized and externalized mental health symptoms, positive internal factors, familial and external social support, educational engagement, environmental factors, and positive childhood experiences. The relationship is further complicated by examining the effects of multiple client-factor variations on the adverse …


Rewriting The Plan: Environmental Justice, Community Resistance, And Governance Power In Hollister, California, Rolan Resendiz Jul 2026

Rewriting The Plan: Environmental Justice, Community Resistance, And Governance Power In Hollister, California, Rolan Resendiz

Dissertations

This dissertation examines how community-led resistance in Hollister, California, challenged environmental injustice and infrastructure governance through grassroots civic action. Focusing on the Hollister Guardians, a coalition of primarily Latinx residents who organized in response to concerns about the city’s sewer system, this qualitative case study introduces the Critical Just Sustainability Policy Praxis (CJSPP) framework, developed by integrating Critical Policy Analysis and the Just Sustainability Paradigm with a praxis-oriented focus on community action. Using critical document analysis of city council meeting minutes, local media coverage, and community-authored texts mainly from 2023 to 2025, the study explores how policy discourse, institutional decision-making, …


Out Of The Briar Patch: Storying Resistance Among Black Male Survivors Of Childhood Sexual Abuse And Its Impact On Their Educational Experiences, Anthony Animuntu Jul 2026

Out Of The Briar Patch: Storying Resistance Among Black Male Survivors Of Childhood Sexual Abuse And Its Impact On Their Educational Experiences, Anthony Animuntu

Dissertations

This study examines the lack of support within educational settings for Black boys who are survivors of childhood sexual abuse (CSA). Despite growing attention to trauma-informed practices, the experiences of Black male survivors remain largely absent from educational research. Using a qualitative, phenomenological approach informed by critical autoethnography, semi-structured interviews were conducted with five African American men reflecting on their schooling experiences as CSA survivors. Axial analysis revealed four central themes: silence as survival and strategic invisibility, shame and internalized distress, institutional misrecognition, and the transformative role of relational care and educational kinship. Findings indicate that participants’ trauma was often …


Avian Conservation And Translocations In The Mariana Archipelago, John V. Bender Jul 2026

Avian Conservation And Translocations In The Mariana Archipelago, John V. Bender

Dissertations

Island birds are among the world’s most imperiled vertebrates, and conservation translocations are increasingly used to combat threats, but their success depends on understanding the mechanics of whether and how to conduct translocations effectively. In the Commonwealth of the Northern Mariana Islands, native forest birds persist across a chain of islands where habitat degradation and loss, invasive species, and extreme weather create persistent conservation challenges. For my dissertation, I investigated how avian conservation programs and translocations can be planned, implemented, and improved under biological, logistical, and social uncertainty. For Chapter 1 I analyzed 15 years of avian translocations across seven …


Effect Of Virtual Reality Intervention Of Postoperative Pain In Pediatric Surgical Patients, Tara L. Kempker Jul 2026

Effect Of Virtual Reality Intervention Of Postoperative Pain In Pediatric Surgical Patients, Tara L. Kempker

Dissertations

Problem: Pediatric surgical procedures are associated with preoperative anxiety. Preoperative anxiety is associated with higher postoperative pain. Multiple studies have found that decreasing preoperative anxiety using Virtual Reality (VR) Intervention also decreases postoperative pain scores and use of rescue analgesics in postoperative care units (PACU). However, there is no standardized protocol for use of VR interventions and in our institution, VR was not utilized at all.

Methods: This quality improvement (QI) initiative utilized a quasi-experimental design and convenience sampling. Quantitative data was collected during visits for scheduled operative visits for pediatric surgical patients ages seven to 18 years …


America The Monstrous: The Birth Of American Horror Fiction In The Long Nineteenth Century, Rachel Kietzman Jul 2026

America The Monstrous: The Birth Of American Horror Fiction In The Long Nineteenth Century, Rachel Kietzman

Dissertations

American gothic works that center the affect of horror explore themes of abjection, inhumanity, and monstrosity that impede a coherent expression of American identity. By approaching these works through the lens of horror rather than only as Gothic works, a picture ofa visceral, embodied becoming takes shape: America is a monstrous birth in the most literal sense of the word, a sign and demonstration that unity and uniformity are not the same, that wholeness does not require conformity, and that political choices are paid for in flesh. In short, American horror fiction is the head of Medusa, an apotropaic sign …


Defining Contractile And Age-Specific Remodeling In Atrial Fibrillation, Hannah Cizauskas Jul 2026

Defining Contractile And Age-Specific Remodeling In Atrial Fibrillation, Hannah Cizauskas

Dissertations

Atrial fibrillation (AFib) is the most common cardiac arrythmia worldwide and is characterized by hallmarks including electrical, fibrotic, and hemodynamic remodeling, each of which can cause or be caused by alterations in the contractile apparatus. However, there is little known about contractile remodeling in AFib. While our current understanding of AFib lacks contractile remodeling, it also largely ignores the contribution of aging-induced remodeling. Aging is the strongest risk factor for AFib development, with most patients diagnosed with AFib over the age of 70, and aging also involves the three molecular hallmarks of AFib, which could explain increased susceptibility of AFib …


Exploring Primary Care Providers’ Compassionate Care And Their Evidence-Based Practice With Death, Grief, And Loss: Patient Experience And Perspective, Kathryn Krzykala Jul 2026

Exploring Primary Care Providers’ Compassionate Care And Their Evidence-Based Practice With Death, Grief, And Loss: Patient Experience And Perspective, Kathryn Krzykala

Dissertations

Research on primary care providers’ (PCPs) education regarding Death, Grief, and Loss (DGL) remains limited. Specifically, data is lacking regarding patients' perceptions and opinions on what they need and expect from their PCPs regarding grief and loss. This exploratory mixed-method study comprised 146 participants who had experienced death and non-death loss. It examined participants' perceptions of 1) PCP compassion, 2) PCP utilization of evidence-based grief and loss practices, 3) their own level of comfort discussing DGL with their PCPs during medical visits, and 4) their personal grief and loss experiences. The findings revealed that PCPs' grief-informed evidence-based treatment, as reflected …


Toward Intentional Praxis: A Design Thinking Multi-Case Study Of Cognitive-Constructive Toolkit Implementation In An Elementary Professional Learning Community, Azam Nathaniel Jul 2026

Toward Intentional Praxis: A Design Thinking Multi-Case Study Of Cognitive-Constructive Toolkit Implementation In An Elementary Professional Learning Community, Azam Nathaniel

Dissertations

Among several learning theories that were dynamic and constantly evolving with time, cognitive and constructive theories were predominant in the field of education. However, these theories often included overlapping and contrasting concepts, contributing to confusion in terminology among teachers and limited explicit use in instructional practice. Within the context of K-12 education, teachers demonstrated conceptual awareness of cognitive and constructive learning theories; however, the theories were not a part of day-to-day conversations and were minimally identified in practice. Instead, the theories were implicitly applied as teachers balanced competing professional responsibilities, including daily routines, syllabus requirements, district standards, new initiatives, differentiated …


Neural Correlates Of Anger Rumination To A Personal Event And Subsequent Changes In Working Memory, Mairin Claire Madison Cotter Jul 2026

Neural Correlates Of Anger Rumination To A Personal Event And Subsequent Changes In Working Memory, Mairin Claire Madison Cotter

Dissertations

Rumination is a maladaptive coping strategy that is associated with the emergence and maintenance of several psychological disorders and related symptomatology and thus has been proposed as a transdiagnostic risk factor. Recent work has focused on patterns of brain activation during rumination to sadness; however, less is known about brain activation patterns in response to anger-inducing events and how anger rumination may influence working memory. This study sought to identify potential neurophysiological correlates (through electroencephalography; EEG) of anger rumination, examine how anger rumination subsequently impacts working memory performance, and determine whether neurophysiological correlates of anger rumination are associated with working …


Investigating The Role Of Cellular Senescence On Vestibular Dysfunction In Repetitive Mild Traumatic Brain Injury, Michael Volyanyuk Jun 2026

Investigating The Role Of Cellular Senescence On Vestibular Dysfunction In Repetitive Mild Traumatic Brain Injury, Michael Volyanyuk

Dissertations

Vestibular dysfunction is a prevalent and persistent consequence of mild traumatic brain injury (mTBI). Clinical reports reveal that women experience vestibular deficits more frequently than men following mTBI. Despite the high prevalence and debilitating nature of vestibular symptoms, preclinical literature evaluating mTBI-associated vestibular impairments is limited. Emerging evidence demonstrates that cellular senescence is involved in the pathological molecular sequela of mTBI. It has been shown that senescence contributes to cognitive deficits following repetitive mTBI (rmTBI); however, its role in rmTBI-associated vestibular dysfunction remains unexplored. This body of work investigated the role of cellular senescence on rmTBI-induced vestibular dysfunction in both …


An Untapped Resource: Exploring The Role Of Spirituality In The Psychological Healing Of African Asylum-Seekers From A Counselor’S Perspective, Brittany A. Duncan Jun 2026

An Untapped Resource: Exploring The Role Of Spirituality In The Psychological Healing Of African Asylum-Seekers From A Counselor’S Perspective, Brittany A. Duncan

Dissertations

This qualitative study explored how counselors perceive and integrate spirituality into the psychological healing of African asylum-seekers, a population facing compounded cultural, legal, and existential challenges. Using interpretative phenomenological analysis, the study examined the lived experiences of eight counselors working with this population. Findings revealed that counselors’ personal sense of religion influenced their comfort and approach in broaching spiritual topics, with both positive (e.g., spirituality as a source of support and community) and negative (e.g., religion as a source of suffering) associations shaping clinical engagement. Many participants reported limited access to trainings geared towards increasing their cultural competence related to …


Merleau-Ponty On The Crisis Of Natural Philosophy: A Critique Of The Metaphysical Foundations Of Natural Science And Investigations Into The Ontology Of Nature, Kevin Mager Jun 2026

Merleau-Ponty On The Crisis Of Natural Philosophy: A Critique Of The Metaphysical Foundations Of Natural Science And Investigations Into The Ontology Of Nature, Kevin Mager

Dissertations

In this dissertation, I show that Merleau-Ponty’s philosophy of nature is also a radical critique of the metaphysical foundations of natural science. This critique leads us to a new ontology for science, grounded in the lifeworld. I focus on how his philosophy offers a detailed critique of both physicalism and mechanism. For Merleau-Ponty, mechanism is not just the strict adherence to classical causality, but any view that asserts that classical causality has any role to play in reality at all. To replace mechanistic causality, Merleau-Ponty argues that we must conceive of nature as grounded in meaningful possibility. Merleau-Ponty's emphasis on …


Uncovering Dkk1 As A Therapeutically Relevant Target In Aggressive Er+ Breast Cancer Using A Novel Antiestrogen, Kristen Young Jun 2026

Uncovering Dkk1 As A Therapeutically Relevant Target In Aggressive Er+ Breast Cancer Using A Novel Antiestrogen, Kristen Young

Dissertations

Over 70 percent of breast cancers are estrogen receptor-positive (ERα+), meaning that the hormone estrogen drives tumor growth. Although first-line targeted therapies that directly block ERα from hormone-dependent pathologies are initially effective, almost half of patients ultimately progress. These patients show high mutational rates to the ESR1 gene that encodes for ERα. A hotspot missense tyrosine to serine mutation at position 537 (Y537S) initiates hormone-independent, allele-specific transcriptional programs that increase metastasis. While next-generation ERα-targeted therapies show promise, benefits are often limited compared to standard-of-care. Understanding the mechanisms of action used by the Y537S ESR1 breast cancer cells to evade therapeutic …


Well-Being, Resilience, And Trauma During Migration: A Mixed Methods Study Of Venezuelan Migrants In Transit, Margaret S. Port Jun 2026

Well-Being, Resilience, And Trauma During Migration: A Mixed Methods Study Of Venezuelan Migrants In Transit, Margaret S. Port

Dissertations

A substantial body of research has examined the psychological impact of experiences preceding and following migration, yet comparatively little attention has been given to the psychological toll of the migration journey itself. Moreover, due to the relative novelty of the Venezuelan migrant crisis and the community’s arrival in the United States, the psychological impact of Venezuelan migrants’ unique migration experience has been underexamined. This study utilized an explanatory sequential mixed methods design to investigate the relationships between well-being, resilience, and trauma among Venezuelan migrants in Chicago, Illinois, while also exploring their lived experiences of the migration journey. Study participants (n …


Understanding And Enhancing Suicide Prevention Strategies In The Military: The Roles Of Culture, Leadership, And Command Climate, Kelly Johanna Pires Jun 2026

Understanding And Enhancing Suicide Prevention Strategies In The Military: The Roles Of Culture, Leadership, And Command Climate, Kelly Johanna Pires

Dissertations

Military service members are shaped and molded to fit a military culture that emphasizes mission readiness and continuous preparedness. Countless hours are spent training for various situations that can arise. Many trainings are geared toward worst-case scenarios that can cause an increase in stressors and traumatic events. They are expected to demonstrate resilience and overcome adversity to remain mission-ready. This expectation to be mission-ready creates the space for mental health difficulties as well as stigma and avoidance of help-seeking behaviors. In many cases, the desire to stay mission-ready creates a barrier for conversations around mental health. The military emphasizes qualities …


Walking The Path Of Conocimiento: Understanding And Navigating Workplace Conflict Through A Chicana Feminist Lens, Elisa A. Ortega-Schultz Jun 2026

Walking The Path Of Conocimiento: Understanding And Navigating Workplace Conflict Through A Chicana Feminist Lens, Elisa A. Ortega-Schultz

Dissertations

The growing presence of Latinas in the U.S. workforce underscores the need for deeper understanding of their workplace experiences. Latinas represent one of the fastest growing segments of the labor force; however, research consistently shows that this growth is not matched by equitable access to leadership, compensation, or culturally responsive workplace environments. Latinas continue to experience persistent barriers related to pay inequity, career advancement, cultural belonging, and overall well-being.

Conflict frameworks that account for the unique experiences of Latinas are needed, as dominant approaches rooted in neutrality, procedural efficiency, and Western individualism often fail to account for the embodied, relational, …


Long-Covid And Cognition, Mychael Bruce Jun 2026

Long-Covid And Cognition, Mychael Bruce

Dissertations

COVID-19 is an evolving virus that can harm the body’s respiratory and cardiovascular systems. Directly related to COVID-19 are individuals who do not recover from their initial infection, making them long haulers. Long-COVID is transitioning from a range of isolated phenomena to higher prevalence rates in patients who contracted COVID-19. Many individuals report issues with cognitive function, referred to as ‘brain fog’, that affect memory, attention, and even language skills. This literature review addresses the available research on Long-COVID and how persistent infection correlates with cognitive difficulties. It aims to explain the neurobiology of Long-COVID and how Long-COVID interacts within …


Evaluation Of Neuroplastic Changes In Psychological Intervention And Contemporary Treatments Of Depression, Taylor Severance Jun 2026

Evaluation Of Neuroplastic Changes In Psychological Intervention And Contemporary Treatments Of Depression, Taylor Severance

Dissertations

Major depressive disorder is one of the most prevalent mental health disorders worldwide. There is a vast range of treatment options for depression, with varying levels of effectiveness. Recent treatments for depression have expanded, increasing alternative treatments, and it is unknown which treatments have the largest impact on depression. This research was designed to examine the treatments of depression, with a focus on psychotherapy and contemporary treatments such as ketamine, psilocybin, and transcranial magnetic stimulation. A literature review was conducted to assess treatment outcomes and neuroplastic changes in these interventions, as well as combinations of the interventions. Data were evaluated …


Perceptual And Geometric Advances In Crowd Simulation, Bilas Talukdar May 2026

Perceptual And Geometric Advances In Crowd Simulation, Bilas Talukdar

Dissertations

Simulating realistic crowd motion remains a fundamental challenge in computer graphics and multi-agent systems, as it requires modeling both physically plausible interactions and perceptually natural behaviors. Existing crowd simulation methods typically employ simplified geometric abstractions, most commonly circular agent representations, and model navigation using either analytical interaction formulations (e.g., force, velocity, or constraint-based methods) or learned policies derived through reinforcement learning. Despite their effectiveness, these approaches often overlook detailed geometric structure and do not explicitly account for perceptual realism. This dissertation addresses these challenges by improving the realism of virtual crowd simulation through two key advancements: perceptual preference learning and …


Membrane-Engineered Nanotherapeutic Platforms For Drug Delivery: Hollow Fiber Membrane Synthesis Of Lipid Nanoparticles, Biomimetic Nanocarriers, And Nanobubbles, Zhixiang Liu May 2026

Membrane-Engineered Nanotherapeutic Platforms For Drug Delivery: Hollow Fiber Membrane Synthesis Of Lipid Nanoparticles, Biomimetic Nanocarriers, And Nanobubbles, Zhixiang Liu

Dissertations

Lipid-based nanocarriers have emerged as a cornerstone technology for RNA therapeutics, enabling effective intracellular delivery for applications ranging from vaccination to gene regulation. However, current manufacturing approaches, particularly microfluidic-based platforms, face inherent limitations in scalability, throughput, and structural tunability due to their reliance on confined channel geometries and restricted mixing architectures. Addressing these challenges requires fundamentally new strategies that decouple nanoparticle formation from traditional microscale flow constraints while maintaining precise control over physicochemical properties.

This dissertation presents a comprehensive framework for the design, engineering, and application of advanced lipid-based nanocarriers, centered on a hollow fiber membrane (HFM)—assisted nanopore-mediated assembly platform. …


Transcranial Ac Modulation Of Cerebellar Nuclear Activity In Awake Animals, Nuran Kavakli May 2026

Transcranial Ac Modulation Of Cerebellar Nuclear Activity In Awake Animals, Nuran Kavakli

Dissertations

Entrainment of cerebellar nuclear (CN) cells via cerebellar transcranial alternating current stimulation (ctACS) has been reported in animals under ketamine/xylazine anesthesia. Our main objective was to demonstrate modulation of CN activity in unanesthetized, freely moving animals using ctACS. Multi-channel carbon-fiber electrodes were implanted into the interpositus nucleus for recording multi-unit (MU) activity, and thin-film electrodes were implanted subcutaneously over the posterior cerebellum for stimulation. A frequency-domain-based metric was developed to quantify modulation from MU signals. The results demonstrated modulation in a wide range of frequencies (4 Hz-300 Hz) as in anesthetized animals. In contrast, the amplitude of the peak in …