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A Study Of The Stability Of Longitudinal Vorticies In A Poiseuille Flow Modulated By Periodic Wall Heating, Matthew L. Fotia
A Study Of The Stability Of Longitudinal Vorticies In A Poiseuille Flow Modulated By Periodic Wall Heating, Matthew L. Fotia
Digitized Theses
The ability to enhance heat-transfer processes with a minimal amount of added energy expenditure has application in many industrial sectors. One avenue to pursue this is in the use of passive controls to trigger the promotion of secondary topological structures in a flow. These structures can be beneficial to the mixing and the transfer of heat into and out of the working fluid. In this instance, the influence of period heating and cooling patterns in the direction of the flow is considered with regard to the linear- stability of longitudinal vortices in a Poiseuille flow. The growth or suppression of …
Assessment Of Humeral Head Position In Competitive Baseball Players, Melanie S. Werstine
Assessment Of Humeral Head Position In Competitive Baseball Players, Melanie S. Werstine
Digitized Theses
Objectives: 1) to estimate the intra and inter-rater reliability of measures of relative humeral head position based on the palpation of two bony landmarks (operationally defined as the distance between the most anterior border of the acromion to the most anterior aspect of the humeral head), 2) to compare the humerus-to-acromion distance in the dominant and non-dominant shoulders of baseball players and controls, and 3) to compare external and internal range of motion in the dominant and non-dominant shoulders of baseball players and controls. Methods: Sixty healthy participants (30 controls and 30 baseball players) were assessed by two experienced physical …
Assessment Of Rat Lung Volumes Using Hyperpolarized Helium-3 Mr Imaging, M. Reza Akhavan Sharif
Assessment Of Rat Lung Volumes Using Hyperpolarized Helium-3 Mr Imaging, M. Reza Akhavan Sharif
Digitized Theses
In this thesis, the upper-limit volume (gas plus partial tissue volume) as well as absolute volume (gas only) of lungs measured using 3He Magnetic Resonance (3He-MR) imaging is compared with that determined by micro-Computed Tomography (micro-CT) and xenon-enhanced micro-CT (Xe-CT) in normal rats. The upper-limit and absolute volumes obtained from He-MR and air-CT methods were not significantly different (P>0.05). Also, no significant difference was found between the volumes measured from He-MR and Xe-CT methods (P>0.05). The good agreement between the volumes measured from He-MR and air-CT suggests that He MR imaging can be used for quantitative analysis of …
Comparative Education With Historical Sociology: A Study Of Mathematics Education Of Canada And Pakistan, Farrukh A. Chishtie
Comparative Education With Historical Sociology: A Study Of Mathematics Education Of Canada And Pakistan, Farrukh A. Chishtie
Digitized Theses
The recent curricular reforms in mathematics education in Punjab, Pakistan and Ontario, Canada are studied in this work. The countries are first studied individually and then compared against each other. Using historical sociology, differences between traditional and modern education as well as the underlying theories of mathematics learning are incorporated to explain the shifts in the mathematics curricula in both the cases. We also discuss the various aspects of shifts in learning theories as mainly a tension between the traditional and progressive modes of learning. In the case of Punjab, Pakistan, it is found that the revised reform documents as …
Cloning And Expression Of Multidrug Resistance Genes In The Cabbage Looper Moth, Trichoplusia Ni, Olivia D’Souza
Cloning And Expression Of Multidrug Resistance Genes In The Cabbage Looper Moth, Trichoplusia Ni, Olivia D’Souza
Digitized Theses
Three genes encoding multidrug resistance proteins were identified in Trichoplusia ni larvae, named trnMDRl, trnMDR2 and trnMDR3. Their open reading frames were sequenced, and the translated sequences were compared to each other as well as to multidrug resistance proteins from other species. Quantification of their expression in various tissues of caterpillars fed on either artificial diet or organically- grown cabbage revealed upregulation of trnMDRl in Malpighian tubules, integument and fat body, trnMDR2 in fat body and trnMDR3 in brain in response to the plant diet. Sf9 cells stably transformed with either trnMDRl or trnMDR3 were used to assay MDR protein …
Combining High Frequency Oscillatory Ventilation And Exogenous Surfactant Administration In An Acid Induced Lung Injury Model, Alexander J. Aspros
Combining High Frequency Oscillatory Ventilation And Exogenous Surfactant Administration In An Acid Induced Lung Injury Model, Alexander J. Aspros
Digitized Theses
The acute respiratory distress syndrome (ARDS) carries a mortality rate of approximately 30% and is characterized by poor oxygenation, decreased lung compliance, and pulmonary edema. The first study in this thesis examined the combination of high frequency oscillatory ventilation (HFO) and exogenous surfactant treatment in an acid- induced lung injury model in rats. It was hypothesized that HFO and surfactant combined is superior to either intervention individually. The second study tested whether surfactant supplementation with a polymer called chitosan would improve surfactant treatment in the same acid model. It was hypothesized that chitosan added to surfactant would be superior to …
Cellular Basis For Stem Cell Mediated Regeneration Of Damaged Myocardium In A Canine Model For Myocardial Infarct, Caroline N. Culshaw
Cellular Basis For Stem Cell Mediated Regeneration Of Damaged Myocardium In A Canine Model For Myocardial Infarct, Caroline N. Culshaw
Digitized Theses
Heart failure from myocardial infarct (MI) is the leading cause of death in North America. While stem cell therapy for MI has been examined in many animal models and in clinical triais, the ability of stem cells to regenerate damaged myocardium is controversial. I have examined the ability of bone marrow and skeletal muscle derived stem cells to differentiate into cardiac and skeletal muscle following injection into infarcted dog hearts. Immunofluorescent co-localization of myosin heavy chain (MyHC) and the fluorescent cell marker PHK26 demonstrated that, while injected cells could be detected at injection sites, they did not express cardiac or …
Assemblage Theory, Complexity And Contentious Politics: The Political Ontology Of Gilles Deleuze, Nick A. Srnicek
Assemblage Theory, Complexity And Contentious Politics: The Political Ontology Of Gilles Deleuze, Nick A. Srnicek
Digitized Theses
The purpose of this thesis is to reconsider the nature of ontology in contemporary political science, with the belief that such a move can be of great benefit to understanding changes in our era of globalization and terrorism. This is accomplished by examining the ontologies of both social constructivism and critical realism in order to show their reliance upon illegitimate presuppositions, and then developing a novel ontological position on the basis of these criticisms. Gilles Deleuze’s concept of assemblages - and his ontology, more generally - are examined as particularly powerful ways to conceptualize the complexity, dynamism and differences that …
Are There Individual And/Or Roost Signatures In The Echolocation Calls Of Wild Big Brown Bats (Eptesicus Fuscus)?, Elisabeth K. Van Stam
Are There Individual And/Or Roost Signatures In The Echolocation Calls Of Wild Big Brown Bats (Eptesicus Fuscus)?, Elisabeth K. Van Stam
Digitized Theses
Unique individual vocal signatures are widespread among animals living in colonies such as the maternity roosts of Eptesicusfuscus. Such individual signatures have been identified in the echolocation calls of E. fuscus in the laboratory, but have not been demonstrated in the wild. By recording known wild E. fuscus as they emerged from their roosts at dusk, I tested the hypothesis that individual and/or roost signatures exist in the echolocation calls of wild E. fuscus. Analyses of calls of 176 individuals recorded at six different locations indicate that temporal and spectral features appear to contain sufficient variation to identify both roost …
Assessment Of Seismic Hazard And Risk, And Decision-Making Under Uncertainty, Katsuichiro Goda
Assessment Of Seismic Hazard And Risk, And Decision-Making Under Uncertainty, Katsuichiro Goda
Digitized Theses
A simulation-based approach to assess seismic hazard and risk is developed and implemented. Its use together with the seismic hazard model proposed by the Geological Survey of Canada is presented. Sensitivity analyses investigating the effects of smoothing historical seismicity, epistemic uncertainty, attenuation relations, and time-dependent earthquake occurrence on seismic hazard are given. By using the developed lifecycle cost model of a structure and adopting the minimum expected lifecycle cost criterion, the optimal seismic design level for Canadian sites is investigated. Note that the use of the adopted criterion identifies the optimal seismic design level for risk-neutral decision makers. Results suggest …
Bracteoles In Cra Taegus (Rosaceae), Kenneth A. Dvorsky
Bracteoles In Cra Taegus (Rosaceae), Kenneth A. Dvorsky
Digitized Theses
Inflorescence bracteoles of Crataegus (Rosaceae) were investigated with the following objectives: i) to determine the taxonomie significance of bracteoles in Crataegus; and ii) to perform a pilot study on the functions of Crataegus bracteoles. The former was accomplished by a morphometric analysis using 25 bracteole characters from 75 species of Crataegus and 3 outgroup taxa. The latter was accomplished by experiments and observations on bracteole-ant interactions, exudate collection and analysis, and cell organelle staining. These studies revealed: (1) two significantly different bracteole types occur, a symmetric kind found in all species and an asymmetric kind found only in Asiatic species; …
Can I Borrow That? : Strategies Of Inscription, Citation And Mimicry In Contemporary Art., Derek Liddington
Can I Borrow That? : Strategies Of Inscription, Citation And Mimicry In Contemporary Art., Derek Liddington
Digitized Theses
The following thesis, entitled Can I borrow That? : Strategies of Inscription, Citation and Mimicry in Contemporary Art, investigates the current faction of artists working with strategies of citation, mimicry and inscription. In defining this environment I discuss the opposing positions founded in Nicolas Bourriaud’s text Postproduction: Culture as Screenplay: How Art Reprograms the World (2002) and Hal Foster’s text “An Archival Impulse” (2004). To account for the current use of appropriative strategies I argue for the conflation of postproduction and archival strategies within the context of a tertiary sector. In determining the tertiary sector as an environment built on …
Beyond The Dotted Line: Psychological Contracts And Their Relations With Organizational Commitment, Kate Mcinnis
Beyond The Dotted Line: Psychological Contracts And Their Relations With Organizational Commitment, Kate Mcinnis
Digitized Theses
Understanding the commitments both an employee and his or her employer make to each other is important to organizations. I explore these commitments by examining the relation between employee commitments and employer psychological contracts (i.e., promises employers make to their employees). Traditionally, psychological contracts have been measured based on the contents of the contract (e.g., promotion opportunities), making it difficult to generalize findings across work arrangements. Instead, I adopt and extend a new approach to examining psychological contracts by looking at the contracts’ features (e.g., stable). Employees from a variety of organizations completed surveys on their organizational commitment and perceptions …
Atrx Deficiency In The Murine Forebrain Leads To Altered Imprinted Gene Expression, Deanna Charlene Tremblay
Atrx Deficiency In The Murine Forebrain Leads To Altered Imprinted Gene Expression, Deanna Charlene Tremblay
Digitized Theses
X-linked a-thalassaemia mental retardation (ATR-X) syndrome is characterized by severe cognitive delay, broad developmental abnormalities and a-thalassaemia. Disease-causing mutations in the ATRX gene give rise to a malfunctioning protein and result in aberrant DNA methylation at specific repeat sequences. ATRX is a SNF2 chromatin remodeling protein that targets α-globin gene expression, but additional targets remain largely elusive. Using a mouse model in which Atrx is conditionally deleted in the developing forebrain, I show that DNA methylation at repeat sequences is comparable to that found in ATR-X patients. I further describe the identification of specific imprinted genes that are progressively regulated …
An Investigation Into A Role For Follistatin In Early Cardiogenesis In Xenopus Laevis, Zhao Yong
An Investigation Into A Role For Follistatin In Early Cardiogenesis In Xenopus Laevis, Zhao Yong
Digitized Theses
Retinoic acid (RA) plays a crucial role in regulating cardiomyocyte differentiation and heart tube formation, but excess RA inhibits cardiomyocyte differentiation. We have used microarray technology and whole mount in situ hybridization to investigate the mechanism by which RA might alter cardiogenesis. Our results showed that RA inhibits cardiomyocyte differentiation at least partially through increasing follistatin gene expression and decreasing BMP signaling. Using cultured explants of the heart region, we demonstrated that addition of BMP4 and activin rescued the inhibitory effects of follistatin and RA on cardiomyocyte differentiation. These results indicate that the increased follistatin (FS) gene expression, known to …
Brokering Services For Cooperative Distributed Systems: An Agent Privacy-Based Architecture, Abdulmutalib M. Masaud Wahaishi
Brokering Services For Cooperative Distributed Systems: An Agent Privacy-Based Architecture, Abdulmutalib M. Masaud Wahaishi
Digitized Theses
Cooperative distributed systems (CDS) approach is a promising design paradigm that is suitable for many applications such as healthcare, virtual enterprises, ebusiness and tele-learning in which entities have some degree of authority to sharing their capabilities. Brokering is a capability-based coordination approach for CDS. A major challenge of brokering in open environments is to support privacy. Within the context of brokering, we model privacy in terms of the entities’ ability to hide or reveal information related to its identities, requests, and/or capabilities. In this work we present in-depth analysis of the capabilitybased coordination and propose a privacy-based brokering framework and …
Characterizing The Heme Binding Properties Of The Iron Regulated Surface Determinant Proteins Of Staphylococcus Aureus, Mark Christopher Pluym
Characterizing The Heme Binding Properties Of The Iron Regulated Surface Determinant Proteins Of Staphylococcus Aureus, Mark Christopher Pluym
Digitized Theses
Staphylococcus aureus infection is becoming a widespread threat in both hospitals and communities worldwide, resulting in substantial treatment costs and numerous patient deaths. Bacterial survival is largely dependant on the organism’s ability to scavenge iron from a host via specialized pathways. The recently identified cell walland membrane-associated Iron regulated surface determinant (Isd) proteins are one such pathway. They serve to transport iron-containing heme, from hemoglobin, from the environment into the bacterial cell for nourishment. To date very little is known about the heme binding properties of these proteins and the overall Isd heme scavenging mechanism. Through the use of UV-visible …
A Burst-Death Model For Experimental Evolution: Fixation Probabilities And Optimal Bottleneck Times When Generation Times Are Variable, Jennifer Elizabeth Hubbarde
A Burst-Death Model For Experimental Evolution: Fixation Probabilities And Optimal Bottleneck Times When Generation Times Are Variable, Jennifer Elizabeth Hubbarde
Digitized Theses
Estimating the fixation probability of a beneficial mutation has a rich history in theoretical population genetics. However, fixation probabilities are extremely sensitive to assumptions regarding life history. We develop a “burst-death” life history model which assumes that generation times are exponentially distributed, but the number of offspring per individual is fixed. Using this model, we estimate the fixation probability for populations of constant size, and for populations which grow exponentially between periodic population bottlenecks. We then predict the optimal time at which to impose bottlenecks, maximizing the probability that beneficial mutations occur and are not ultimately lost. We find that …
A Feasibility Study Of The Potential To Track Contrast Agent Labelled Dendritic Cells Using Magnetic Resonance Imaging (Spine Title: Potential Of Tracking Labelled Dendritic Cells Using Mri), Bradly Gerald Shrum
Digitized Theses
Magnetic resonance imaging (MRI) can be used to track DC in vivo because it non-invasively combines critical anatomical detail and sensitivity. To identify cells using MRI it is necessary tolabel them with a contrast agent. DC were labelled with superparamagnetic iron oxide (SPIO) ∞ntrast agents for in vivo imaging. It was found that Feridex was taken up intracellularly and has minimal impact on the DC size and expression of cell maturation markers. Following injection into mice, the labelledDC could be detected by in vivo MRI in draining lymph nodes. The MRI data was consistent with histological analysis which confirmed the …
« La Figure De Diane » Sous Les Yeux De Desportes Et D’Aubigné, Emily Low
« La Figure De Diane » Sous Les Yeux De Desportes Et D’Aubigné, Emily Low
Digitized Theses
Quelle image saute à l’imagination quand on entend parler de la figure mythologique de la déesse Diane? La déesse lunaire, chaste et virginale? Diane, déesse de la chasse? Ou bien Diane, déesse de l’enfer? Quelle figure de Diane est favorisée dans la poésie néo- pétrarquiste qui apparaît vers la fin de la Renaissance, où l’on note le détournement noir et sanglant des thèmes pétrarquistes? Pour essayer de répondre à ces questions, il convient d’analyser l’emploi de cette figure mythologique de Diane dans les sonnets amoureux de Desportes et de d’Aubigné. Déjà, il existe plusieurs oeuvres critiques qui examinent les thèmes …
A Neuro-Fuzzy Model For Software Development Effort Estimation, Besa Muslimi
A Neuro-Fuzzy Model For Software Development Effort Estimation, Besa Muslimi
Digitized Theses
In the software industry, a reliable development effort estimation model remains to be the missing piece of the puzzle. Existing estimation models provide one-size-fits-all solutions that fail to produce accurate estimates in most environments. Research has shown that the accomplishment of accurate effort estimates is a long-term process that, above all, requires the extensive collection of effort estimation data by each organization. An effort estimation data point is generally characterized by a set of attributes that are believed to most affect the development effort in the organization. These attributes can then be used as inputs to the effort estimation model. …
A Structure-Function Study Of The Human Dna Polymerase Lambda (Λ), Francis Mwai Kariuki
A Structure-Function Study Of The Human Dna Polymerase Lambda (Λ), Francis Mwai Kariuki
Digitized Theses
The human DNA polymerase lambda (Pol λ) is a recently discovered member of the X-family DNA polymerases that has been shown to be involved in DNA repair and meiotic recombination, where it plays a gap filling role in these two processes. The protein’s primary sequence is organized into an N-terminal BRCAl-C terminai (BRCT) domain, a proline-rich domain and a C-terminus polymerase beta-like (Pol β-like) domain. Studies have shown that the polymerase’s activity is localized at the C-terminus of the protein and that this activity is partially suppressed by the proline-rich domain. Primer extension assays confirmed the inhibitory effects of the …
A Comparison Of Two Families Of Algorithms For Symbolic Polynomials, Matt Malenfant
A Comparison Of Two Families Of Algorithms For Symbolic Polynomials, Matt Malenfant
Digitized Theses
Symbolic polynomials, whose exponents themselves are integer-valued multivariate polynomials, arise often in algorithm analysis. Unfortunately, modern computer algebra systems do not provide ample support for their algebraic structures. Basic operations involving symbolic polynomials are indeed trivial (addition, multiplication, derivatives); however, other crucial operations remain much more difficult, such as factorization and GCD. Watt has given two separate methods to solve these challenging problems. The first uses a change of variables, e.g. xn to X, xnm to Y. Doing so increases the number of variables potentially exponentially. Evaluation/Interpolation is used in the second algorithm. Projection methods introduce fewer variables but have …
A Real Connection: Cross-Media Youth Programming, Critical Pedagogy And The Case Of Renegadepress.Com, Maren Elizabeth Dick
A Real Connection: Cross-Media Youth Programming, Critical Pedagogy And The Case Of Renegadepress.Com, Maren Elizabeth Dick
Digitized Theses
With the work of critical pedagogy theorists Paolo Freire and Henry A. Giroux providing a theoretical foundation, this thesis will examine the youth television show and website renegadepress.com to consider ways in which cross-media youth programming affords reflection, critical thinking or participation in civic life. As an interactive, issues-oriented youth series airing on APTN and several provincial education stations, renegadepress.com fits into a Canadian tradition of educational and issues-oriented children’s and youth programming. By carrying out a textual analysis of the renegadepress, com television show and website, interviewing the creators/producers of renegadepress, com, observing as renegadepress, com was used in …
A Critical Analysis Of The Relationship Among Organizational Culture, Teachers’ Values And Attitudes About Teaching And Learning, And Pedagogical Approaches At An Overseas American School In Egypt, Carissa Maclennan
Digitized Theses
It is the intent of this thesis to highlight the role of culture on the phenomenon of educational borrowing. This study provides a critical analysis through the lenses of globalization theory and comparative education to determine the relationship among organizational culture, teachers’ values and attitudes about teaching and learning, and pedagogical approaches at a private American school in Egypt. This urban school instructs Egyptian students, employs both North American and Egyptian teachers, and implements an American curriculum. This ethnography included six participants employed at the school where the study was based; two Egyptian teachers, two NorthAmerican teachers, and two administrators. …
Adaptive Setup Planning And Dispatching For Machining Job Shop Operations, Ningxu Cai
Adaptive Setup Planning And Dispatching For Machining Job Shop Operations, Ningxu Cai
Digitized Theses
The dynamic environment of a shop floor is usually characterized with operation uncertainties. An ideal shop floor should be the one that effectively uses available manufacturing resources to achieve the best overall performance according to real-time system conditions and requirements. It thus requires an adaptive means for task planning and execution that is responsive to dynamic changes of distributed production capacity and functionality. The objective of this research is to develop an adaptive setup planning system that is responsive to dynamic changes during machining job shop operations. Setup is the most commonly used task dispatching and scheduling unit in a …
Accelerated Zone-2 Trip Algorithm For A Non-Pilot Distance Relay, German Rosas Ortiz
Accelerated Zone-2 Trip Algorithm For A Non-Pilot Distance Relay, German Rosas Ortiz
Digitized Theses
Distance relays use time stepped protection zones for coordination purposes. The time delay introduced by zone-2 distance relays limits the use of these devices for extra high voltage (EHV) applications since the fast fault clearance requirement is not achieved. Transmission lines are normally protected by means of intercommunicated protection schemes that make use of a dedicated channel in order to overcome the delay. However, this channel is also prone to failure. It could be advantageous to provide the line with fast protection coverage for cases when a communication channel is not available. This thesis presents the analysis, simulation, and implementation …
An Estimation Of The Reliability And Validity Of A Weightbearing Measure Of Ankle Dorsiflexion Range Of Motion, Martin D. Chisholm
An Estimation Of The Reliability And Validity Of A Weightbearing Measure Of Ankle Dorsiflexion Range Of Motion, Martin D. Chisholm
Digitized Theses
The Lunge Test Difference Score (LTDS) measures ankle dorsiflexion ROM in weightbearing. Its reliability and validity were estimated in 53 participants (34.6 ± 13.9 years) with orthopaedic ankle injuries. The LTDS, the Lower Extremity Functional Scale, and the American Academy of Orthopaedic Surgeons Global Foot and Ankle Scale were recorded on three occasions. Test-retest reliability was determined from the results of the final two testing sessions. Correlations between the LTDS and the functional measures were used to validate the LTDS. Correlation between the Global Rating of Change scale and change in LTDS quantified sensitivity to change. The ICC2,1 was 0.94 …
An Integrated Cognitive-Affective Model Of Suicidal Thinking And Behavior, Laura L. Fazakas-Dehooa
An Integrated Cognitive-Affective Model Of Suicidal Thinking And Behavior, Laura L. Fazakas-Dehooa
Digitized Theses
Despite a growing body of research, a ∞mprehensive understanding of suicide remains elusive. The current dissertation involved the development of an integrated cognitive affective theory of suicidal thinking and behavior, and the initial assessment of components of this theoretical model in three separate, but related studies. In Study 1, the integrity of the model was assessed in a sample of 397 (83 male and 314 female) undergraduate students. The resulting fit indices (CFI=.87; GFI=.90; RMSEA=.09) of the structural equation modeling (SEM) analysis indicated an adequate fit between the hypothesized model and the data in the sample, with the model amounting …
A Description Of The Functions Of Observational Learning In Sport, Barbara D. Law
A Description Of The Functions Of Observational Learning In Sport, Barbara D. Law
Digitized Theses
The purpose of this dissertation was to describe athletes’ use of the functions of observational learning in various sport situations. A secondary purpose was to explore whether the Functions of Observational Learning Questionnaire (FOLQ; Cumming et al., 2005) could be used to examine naturalistic observational learning use with various groups of sport participants. To achieve these purposes, three studies were conducted. Study 1 examined the relationship between skill level, age, and use of the functions of observational learning in a sample of golfers. Study 2 explored the relationship between use of the functions of observational learning and self-efficacy beliefs in …