Digital Commons Network^™

Oocyte Peptides As Paracrine Tools For Ovarian Stimulation And Oocyte Maturation., David G Mottershead, Andrew J Watson

Obstetrics & Gynaecology Publications

Recent studies report the production and isolation of a stable bioactive recombinant human bone morphogenetic protein 15 (rhBMP15) that is appropriately processed in HEK-293 cells and activates the SMAD 1/5/8 pathway in mouse granulosa cell cultures. Further, the purified rhBMP15 induces the expression of genes associated with cumulus expansion. Thanks to recent research, we have a greater understanding of the importance of the dialogue that occurs between the oocyte and the granulosa cell layer with regard to regulating folliculogenesis and the acquisition of oocyte developmental competence and maturation. BMP15 is one of the critical components of these intra-follicular communication pathways. …

Transnational Understandings Of Australian Aboriginal Sporting Migration: Sporting Walkabout, John Maynard

Aboriginal Policy Research Consortium International (APRCi)

This article will examine the impact of Aboriginal sporting participation and movement around the globe. The experiences, influences and inspiration that Aboriginal sporting men and women absorbed while travelling internationally have played a prominent role in changing the perceptions and understanding of Aboriginal people to the wider populace. The later stages of the nineteenth and early twentieth century were a period in which Aboriginal people were erroneously categorized as a dying race, belonging to the Stone Age and uneducable. However the influence of sport and travel ensured that Aboriginal cricketers, footballers, athletes, boxers and horsemen and -women played a part …

An Assessment Of Kigali, Rwanda, Helen Awai, Silvia Marroquin Ponce, Nilmi Senaratna

Empowerment and Development

This assessment includes an introduction to Rwandan history and health concerns, probiotic yogurt impacts on these health effects, and three assessments. In the three compiled reports, the situation in Kigali, Rwanda will be assessed in order to ensure that a sustainable FITI yogurt project with the guidance of Western Heads East can succeed. The report will identify key partners and infrastructure needed, milk availability in order to establish the means to produce the yogurt and finally it will assess the business and marketing tactics necessary for a sustainable operation. It will identify the steering committee needed to lead the women, …

Resting State Default-Mode Network Connectivity In Early Depression Using A Seed Region-Of-Interest Analysis: Decreased Connectivity With Caudate Nucleus., Robyn Bluhm, Peter Williamson, Ruth Lanius, Jean Theberge, Maria Densmore, Robert Bartha, Richard Neufeld, Elizabeth Osuch

Department of Medicine Publications

AIM: Reports on resting brain activity in healthy controls have described a default-mode network (DMN) and important differences in DMN connectivity have emerged for several psychiatric conditions. No study to date, however, has investigated resting-state DMN in relatively early depression before years of medication treatment. The objective of the present study was, therefore, to investigate the DMN in patients seeking help from specialized mental health services for the first time for symptoms of depression.

METHODS: Fourteen depressed subjects and 15 matched controls were scanned using 4-T functional magnetic resonance imaging while resting with eyes closed. All but one subject was …

Adding A Motivational Interviewing Pretreatment To Cognitive Behavioral Therapy For Generalized Anxiety Disorder: A Preliminary Randomized Controlled Trial., Henny A Westra, Hal Arkowitz, David J A Dozois

Psychology Publications

Seventy-six individuals with a principal diagnosis of generalized anxiety disorder (GAD) were randomly assigned to receive either an MI pretreatment or no pretreatment (NPT), prior to receiving CBT. Significant group differences favoring the MI-CBT group were observed on the hallmark GAD symptom of worry and on therapist-rated homework compliance, which mediated the impact of treatment group on worry reduction. Adding MI pretreatment to CBT was specifically and substantively beneficial for individuals with high worry severity at baseline. There was evidence of relapse at 6-month follow-up for high severity individuals who received MI-CBT, but significant moderator effects favoring the high severity …

Changes In Self-Schema Structure In Cognitive Therapy For Major Depressive Disorder: A Randomized Clinical Trial., David J A Dozois, Peter J Bieling, Irene Patelis-Siotis, Lori Hoar, Susan Chudzik, Katie Mccabe, Henny A Westra

Psychology Publications

Negative cognitive structure (particularly for interpersonal content) has been shown in some research to persist past a current episode of depression and potentially to be a stable marker of vulnerability for depression (D. J. A. Dozois, 2007; D. J. A. Dozois & K. S. Dobson, 2001a). Given that cognitive therapy (CT) is highly effective for treating the acute phase of a depressive episode and that this treatment also reduces the risk of relapse and recurrence, it is possible that CT may alter these stable cognitive structures. In the current study, patients were randomly assigned to CT+ pharmacotherapy (n = 21) …

Increased Yields And Simplified Purification With A Second-Generation Cobalt Catalyst For The Oxidative Formation Of Trans-Thf Rings., Cory Palmer, Nicholas A Morra, Andrew C Stevens, Barbora Bajtos, Ben P Machin, Brian L Pagenkopf

Chemistry Publications

The synthesis of a second-generation cobalt catalyst for the formation of trans-THF products via the Mukaiyama aerobic oxidative cyclization is reported. Two procedures have been developed with the new water-soluble catalyst that give superior yields and greatly simplify purification compared to the previous catalysts.

Leaving University Without Graduating: Evidence From Canada’S Youth In Transition Survey, Wolfgang Lehmann, Eric Tenkorang

Sociology Presentations

No abstract provided.

Worker Control As A Facilitator In The Match Between Education And Jobs, Johanna Weststar

Management and Organizational Studies Publications

This article examines the relationship between worker control and subjective underemployment among workers who have more education than is needed for entry into their jobs (credential underemployment). Results indicate that social and technical controls are related to a greater sense of education–job matching. Workers who have credential underemployment are less likely to report subjective underemployment (underutilization and lack of fit between education and job) if they have higher levels of workplace control. This article contains implications for job design and the role of employers and managers in fostering the utilization of their workforces.

Electrochemical And Photovoltaic Properties Of Electropolymerized Poly(Thienyl-Silole)S, Joshua C. Byers, Paul M. Dicarmine, Mahmoud M. A. R. Moustafa, Xin Wang, Brian Pagenkopf, Oleg A. Semenikhin

Chemistry Publications

Electrochemical and photoelectrochemical properties were studied of a series of donor−acceptor materials based on polythiophene modified with silole moieties. The materials were prepared by electrochemical anodic polymerization of 2,5-bis([2,2′-bithiophen]-5-yl)-1,1-dimethyl-3,4-diphenylsilole and 2,5-bis([2,2′-terthiophen]-5-yl)-1,1-dimethyl-3,4-diphenylsilole, as well as copolymerization of these monomers with 2,2′-bithiophene. Photocurrent measurements showed that introduction of silole resulted in a considerable enhancement of the photovoltaic properties of silole-containing materials and especially the fill factor. However, as demonstrated by Mott−Schottky measurements, electropolymerized silole-containing materials showed a substantial degree of disorder and high density of states in the midgap, which negatively affected their photovoltaic properties. Atomic force microscopy (AFM) and phase imaging …

The Copyright Debate: Finding The Right Balance For Teaching, Research, And Cultural Expression, Samuel E. Trosow

FIMS Presentations

No abstract provided.

Victims Of Violence Among Indigenous Mothers Living With Dependent Children, Kyllie Cripps, Catherine M. Bennett, Lyle C. Gurrin, David M. Studdert

Aboriginal Policy Research Consortium International (APRCi)

Objective: Toidentifyindividualandhouseholdfactorsassociatedwithviolenceamong Australian Indigenous women with dependent children. Design and participants: Univariate and multivariable analysis of data from the 2002 National Aboriginal and Torres Strait Islander Social Survey, stratified by area.

Main outcome measure: Self-reported experience of being a victim of violence in the previous year. Results: OneinfourIndigenouswomenlivingwithdependentchildrenyoungerthan 15 years reported being victims of violence in the previous year; this corresponds to an estimated 24 221 Indigenous mothers (95% CI, 21 507–26 935) nationwide. Violence was more prevalent in regional areas and cities than remote areas. In remote areas, mothers who had been removed from their natural families during childhood …

Integrating Research Into Lis Field Experiences In Academic Libraries, Selinda Adelle Berg, Kristin Hoffmann, Diane Dawson

Western Libraries Publications

Field experiences function as a link between LIS theory and practice. Students should be provided with an experience that is a true reflection of the professional environment. The increasing focus on research by academic librarians provides an opportunity and responsibility to integrate research into the field experiences of LIS students.

A General Asymmetric Aldol Reaction Of Silyl Ketene Acetals Derived From Simple Esters To Aryl Alpha-Ketoesters, Brian Pagenkopf, Julie Le Engers

Chemistry Publications

No abstract provided.

Early Psychosis: A Novel Gateway For Suicide Prevention, Amresh Srivastava

Psychiatry Presentations

No abstract provided.

The Effects Of Field-Of-View And Patient Size On Ct Numbers From Cone-Beam Computed Tomography., Katrina Y T Seet, Arvand Barghi, Slav Yartsev, Jacob Van Dyk

Oncology Publications

Cone-beam computed tomography (CBCT) is used for patient alignment before treatment and is ideal for use in adaptive radiotherapy to account for tumor shrinkage, organ deformation and weight loss. However, CBCT images are prone to artifacts such as streaking and cupping effects, reducing image quality and CT number accuracy. Our goal was to determine the optimum combination of cone-beam imaging options to increase the accuracy of image CT numbers. Several phantoms with and without inserts of known relative electron densities were imaged using the Varian on-board imaging system. It was found that CT numbers are most influenced by the selection …

Open Access Publishing In The Biological/Medical Sciences, J. Madrenas

Robarts Immunology and Transplantation Presentations

No abstract provided.

Open Access And Its Social Benefits, Ajit Pyati

FIMS Presentations

No abstract provided.

Open Access Week (Retention Of Author Rights), Mark Perry

Law Presentations

No abstract provided.

Clinical Utility Of The 2-Minute Walk Test For Older Adults Living In Long-Term Care, D. M. Connelly, B. K. Thomas, S. J. Cliffe, W. M. Perry, R. E. Smith

Physical Therapy Publications

Purpose: This study's purposes were to examine the measurement properties of the 2-minute walk test (2MWT), to illustrate the use of reliability coefficients in clinical practice, and to estimate sample size for a subsequent validity study. Method: Sixteen residents of long-term care (LTC; mean age = 87 years) completed two 2MWTs with Rater A and two 2MWTs with Rater B on test days 1 and 2, approximately 1 week apart. On a third test day, subjects completed one trial of the Berg Balance Scale (BBS), timed up-and-go (TUG) test, and 6-minute walk test (6MWT) with Rater A. On 2 other …

The Lambert W Function And Quantum Statistics, Sree Ram Valluri, M. Gil, D. J. Jeffrey, Shantanu Basu

Physics and Astronomy Publications

We present some applications of the Lambert W function (W function) to the formalism of quantum statistics (QS). We consider the problem of finding extrema in terms of energy for a general QS distribution, which involves the solution of a transcendental equation in terms of the W function. We then present some applications of this formula including Bose–Einstein systems in d dimensions, Maxwell–Boltzmann systems, and black body radiation. We also show that for the appropriate parameter values, this formula reduces to an analytic expression in connection with Wien’s displacement law that was found in a previous study. In addition, we …

Community-Based Suicide Prevention Research In Remote On-Reserve First Nations Communities, Corinne A. Isaak, Mike Campeau, Laurence Y. Katz, Murray W. Enns, Brenda Elias, Jitender Sareen

Aboriginal Policy Research Consortium International (APRCi)

Suicide is a complex problem linked to genetic, environmental, psychological and community factors. For the Aboriginal population more specifically, loss of culture, history of traumatic events, individual, family and community factors may also play a role in suicidal behaviour. Of particular concern is the high rate of suicide among Canadian Aboriginal youth. While the need to develop interventions to reduce suicidal behaviour for First Nations on-reserve populations is evident, there may be an element of distrust of researchers by Aboriginal communities. Furthermore, research in mental health and specifically suicide is much more sensitive than studying medical illnesses like diabetes. Clearly, …

Dr. Balachandra Rajan: From India To Canada, Fragments In Search Of A Narrative - In Memoriam, Teresa Hubel

Department of English Publications

A heartfelt memorial piece for Dr. Balachandra Rajan, an Indian diplomat and poetic scholar, written by Teresa Hubel.

Introduction:

While preparing to write this tribute to Dr. Balachandra Rajan, I found myself wondering what in his eminent life I should be recalling for your benefit. Which events or personal preferences, habits, gestures, or even political commitments and publications can be tallied up to create some kind of coherent narrative that conveys the gist of him? The dilemma is that, when it comes to Dr. Rajan (who in my memory can never be remembered as anyone other than Dr. Rajan, not …

What Factors Predict Outcome At Relapse After Previous Esophagectomy And Adjuvant Therapy In High-Risk Esophageal Cancer?, Edward Yu, Patricia Tai, Richard Malthaner, Larry Stitt, George Rodrigues, Rashid Dar, Brian Yaremko, Jawaid Younus, Michael Sanatani, Mark Vincent, Brian Dingle, Dalilah Fortin, Richard Inculet

Oncology Presentations

Management of patients who have disease relapse after completion of surgery and adjuvant chemo-radiation (CRT) is controversial.

Some oncologists would advocate intensive therapeutic intervention due to promising experience on treatment for recurrence disease while others would recommend palliative support due to the concerns for poor patient outcome post disease recurrence.

In Addition, it is not clear if patient outcome is improved post adjuvant CRT when patients at risk have resection margin involvement and if time interval to recurrence can affect patient survival post relapse.

The present study was conducted to determine what factors will affect patient outcome at relapse after …

The Uqam Mummy – The Use Of Non-Destructive Imaging To Reconstruct An Ancient Osteobiography And To Document Modern Malfeasance, Andrew J. Nelson, Andrew D. Wade, R. Hibbert, B. Macdonald, M. Donaldson, R. Chatelain, N. Nguyen, V. Lywood, G. Gibson, M. Trumpour, S. N. Friedman, P. V. Granton, J. Morgan, David W. Holdsworth, I. A. Cunningham

Anthropology Presentations

An Egyptian mummy and her coffin dating to the 26th Dynasty were donated to the École de Beaux Arts in Montreal in 1927. This mummy has been in the collection of the Université du Québec à Montréal since 1967. Inscriptions on the elaborate coffin identify the individual as Hetep-Bastet. In 1969, the mummy was attacked by a protester, who caused extensive damage. The mummy was scanned once over a decade ago. However, computed tomography (CT) technology has advanced a great deal since that time, and some conclusions reached were somewhat suspect (e.g. that she suffered from a large dental abscess …

Ethical Challenges In Icu Research, Charles Weijer

Philosophy Presentations

No abstract provided.

When Can Physicians Say “No” To Families And Patients?, Charles Weijer

Philosophy Presentations

No abstract provided.

The Vesicular Acetylcholine Transporter Is Required For Neuromuscular Development And Function, Braulio M. De Castro, Xavier De Jaeger, Cristina Martins-Silva, Ricardo D. F. Lima, Ernani Amaral, Cristiane Menezes, Patricia Lima, Cintia M. L. Neves, Rita G. Pires, Thomas W. Gould, Ian Welch, Christopher Kushmerick, Cristina Guatimosim, Ivan Izquierdo, Martin Cammarota, Jane R. Rylett, Marcus V. Gomez, Marc G. Caron, Ronald W. Oppenheim, Marco A. M. Prado, Vania F. Prado

Anatomy and Cell Biology Publications

The vesicular acetylcholine (ACh) transporter (VAChT) mediates ACh storage by synaptic vesicles. However, the VAChT-independent release of ACh is believed to be important during development. Here we generated VAChT knockout mice and tested the physiological relevance of the VAChT-independent release of ACh. Homozygous VAChT knockout mice died shortly after birth, indicating that VAChT-mediated storage of ACh is essential for life. Indeed, synaptosomes obtained from brains of homozygous knockouts were incapable of releasing ACh in response to depolarization. Surprisingly, electrophysiological recordings at the skeletal-neuromuscular junction show that VAChT knockout mice present spontaneous miniature end-plate potentials with reduced amplitude and frequency, which …

Rough Waters: Navigating Hard Times In The Scholarly Communication Marketplace, Adrian K. Ho

Western Libraries Publications

No abstract provided.

Student Reviewer Training For Western Undergraduate Research Journal: Health And Natural Sciences, Tricia Gray

Biology Presentations

No abstract provided.