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2001

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A Longitudinal Investigation Of Information Processing And Cognitive Organization In Clinical Depression: Stability Of Schematic Interconnectedness., D J Dozois, K S Dobson Dec 2001

A Longitudinal Investigation Of Information Processing And Cognitive Organization In Clinical Depression: Stability Of Schematic Interconnectedness., D J Dozois, K S Dobson

Psychology Publications

This study longitudinally investigated information processing and cognitive organization in clinical depression. The main hypothesis was that individuals whose depression had remitted would show a significant cognitive shift on information processing (e.g., deactivation of negative processing) but not on cognitive organizational tasks, Forty-five individuals with clinical depression completed 2 information processing and 2 cognitive organizational tasks at initial assessment. At 6-month follow-up, the sample (23 remitted, 22 stable depressed) was readministered the tasks. As expected, information processing shifted significantly in individuals who had improved symptomatically, whereas negative cognitive organizational indices remained stable. The implications of these results are discussed as …


Sensitivity Of Bovine Blastocyst Gene Expression Patterns To Culture Environments Assessed By Differential Display Rt-Pcr., D R Natale, P A De Sousa, M E Westhusin, A J Watson Nov 2001

Sensitivity Of Bovine Blastocyst Gene Expression Patterns To Culture Environments Assessed By Differential Display Rt-Pcr., D R Natale, P A De Sousa, M E Westhusin, A J Watson

Obstetrics & Gynaecology Publications

The use of culture media to support the development of preimplantation embryos to the blastocyst stage is often associated with detrimental effects on normal development. These effects have been uncovered largely by investigating the phenotypic abnormalities displayed by fetuses and newborns derived from cultured preimplantation embryos. Research to understand the impact of culture on the embryonic developmental programme has focused on embryo metabolism, gene expression and genomic imprinting. We have used differential display RT-PCR to examine culture influences on global transcript pools in bovine embryos. Others have examined culture influences on candidate "marker genes" in cultured murine, ovine and bovine …


Component-Based Software Development, Luiz Fernando Capretz, Miriam Capretz, Dahai Li Nov 2001

Component-Based Software Development, Luiz Fernando Capretz, Miriam Capretz, Dahai Li

Electrical and Computer Engineering Publications

Component-based software development (CBSD) strives to achieve a set of pre-built, standardized software components available to fit a specific architectural style for some application domain; the application is then assembled using these components. Component-based software reusability will be at the forefront of software development technology in the next few years. This paper describes a software life cycle that supports component-based development under an object-oriented framework. Development time versus software life cycle phases, which is an important assessment of the component-based development model put forward, is also mentioned.


Critical Analysis Of Cerebrovascular Autoregulation During Repeated Head-Up Tilt., R L Hughson, M R Edwards, D D O'Leary, J K Shoemaker Oct 2001

Critical Analysis Of Cerebrovascular Autoregulation During Repeated Head-Up Tilt., R L Hughson, M R Edwards, D D O'Leary, J K Shoemaker

Kinesiology Publications

BACKGROUND AND PURPOSE: Cerebrovascular autoregulation has been described with a phase lead of cerebral blood flow preceding changes in cerebral perfusion pressure (CPP), but there has been less focus on the effect of CPP on cerebral vascular resistance. We investigated these relations during spontaneous fluctuations (control) and repeated head-up tilt.

METHODS: Eight healthy adults were studied in supine rest and repeated tilt with 10-second supine, 10 seconds at 45 degrees head-up tilt for a total of 12 cycles. Cerebral blood flow was estimated from mean flow velocity (MFV) by transcranial Doppler ultrasound, CPP was estimated from corrected finger pressure (CPP(F)), …


Discrimination Of Computer-Graphic Stimuli By Mice: A Method For The Behavioral Characterization Of Transgenic And Gene-Knockout Models., T J Bussey, L M Saksida, L A Rothblat Aug 2001

Discrimination Of Computer-Graphic Stimuli By Mice: A Method For The Behavioral Characterization Of Transgenic And Gene-Knockout Models., T J Bussey, L M Saksida, L A Rothblat

Brain and Mind Institute Researchers' Publications

An automated method is described for the behavioral testing of mice in an apparatus that allows computer-graphic stimulus material to be presented. Mice responded to these stimuli by making a nose-poke toward a computer monitor that was equipped with a touchscreen attachment for detecting responses. It was found that C57BL/6 mice were able to solve single-pair visual discriminations as well as 3-pair concurrent visual discriminations. The finding that mice are capable of complex visual discriminations introduces the possibility of testing mice on nonspatial tasks that are similar to those used with rats, monkeys, and humans. Furthermore, the method seems particularly …


Review Of Reginald Pole: Prince And Prophet By Thomas F. Mayer., Margaret Mcglynn Jul 2001

Review Of Reginald Pole: Prince And Prophet By Thomas F. Mayer., Margaret Mcglynn

History Publications

No abstract provided.


Cyclooxygenase-2 And Prostaglandin E(2)(Pge(2)) Receptor Messenger Rnas Are Affected By Bovine Oocyte Maturation Time And Cumulus-Oocyte Complex Quality, And Pge(2) Induces Moderate Expansion Of The Bovine Cumulus In Vitro., M D Calder, A N Caveney, M E Westhusin, A J Watson Jul 2001

Cyclooxygenase-2 And Prostaglandin E(2)(Pge(2)) Receptor Messenger Rnas Are Affected By Bovine Oocyte Maturation Time And Cumulus-Oocyte Complex Quality, And Pge(2) Induces Moderate Expansion Of The Bovine Cumulus In Vitro., M D Calder, A N Caveney, M E Westhusin, A J Watson

Obstetrics & Gynaecology Publications

Expression of cyclooxygenase-2 (COX-2) and prostaglandin E(2) (PGE(2)) receptor 2 (EP2) are necessary for rodent cumulus expansion in vivo. Prostaglandin E(2) receptor 3 (EP3) has been detected in bovine preovulatory follicles and corpora lutea. The current experiments examined the effect of PGE(2) on bovine cumulus expansion in vitro and expression of COX-2, EP1, EP2, EP3, and EP4 mRNAs in bovine cumulus-oocyte complexes (COCs) at 0, 6, 12, 18, and 24 h time points during maturation in vitro. Concentrations of PGE(2) above 50 ng/ml resulted in moderate cumulus expansion of bovine COCs, but expansion did not occur in the absence of …


Working Towards Regional Agreements: Recent Developments In Co-Operative Resource Management In Canada’S British Columbia, Cathy Robinson Jul 2001

Working Towards Regional Agreements: Recent Developments In Co-Operative Resource Management In Canada’S British Columbia, Cathy Robinson

Aboriginal Policy Research Consortium International (APRCi)

No abstract provided.


Spirituality In Late Adulthood, Lisa M. Heintz, Imants Barušs Jun 2001

Spirituality In Late Adulthood, Lisa M. Heintz, Imants Barušs

Psychology

MacDonald's Expressions of Spirituality Inventory was used to examine spirituality in late adulthood using a sample of 30 people (22 women, 8 men) whose mean age was 72.6 yr. While average scores are higher on scales measuring spiritual and religious beliefs and practices for the sample than for a standardization group of undergraduate students with a mean age of 21.0 yr., means are lower on scales measuring paranormal beliefs. Low scores on death anxiety are correlated only with Existential Well-being and age. And, while some religious behaviors such as frequent religious practice, prayer, and church attendance are correlated with some …


Amino Acid Concentrations In Fluids From The Bovine Oviduct And Uterus And In Ksom-Based Culture Media., Y M Elhassan, G Wu, A C Leanez, R J Tasca, A J Watson, M E Westhusin Jun 2001

Amino Acid Concentrations In Fluids From The Bovine Oviduct And Uterus And In Ksom-Based Culture Media., Y M Elhassan, G Wu, A C Leanez, R J Tasca, A J Watson, M E Westhusin

Obstetrics & Gynaecology Publications

Amino acids in bovine oviductal and uterine fluids were measured and compared with those in modified simplex optimized medium (KSOM) supplemented with either fetal calf serum or Minimum Essential Medium amino acids in addition to bovine serum albumin, fetal calf serum or polyvinyl alcohol. Concentrations of cysteine, threonine, tryptophan, alanine, aspartate, glycine, glutamate, proline, beta-alanine, and citrulline were higher in oviductal fluids than in KSOM-based culture media. Nonessential and essential amino acids were present in ratios of 5:1 and 2:1 in oviductal and uterine fluids, respectively. Concentrations of alanine (3.7 mM), glycine (14.1 mM) and glutamate (5.5 mM) were high …


Beyond Librarianship: Are Librarians Becoming Isolated In The New Information Age?, Margaret Ann Wilkinson, Roma Harris May 2001

Beyond Librarianship: Are Librarians Becoming Isolated In The New Information Age?, Margaret Ann Wilkinson, Roma Harris

Law Publications

This paper continues a series exploring the perceptions of entering university students about the roles of librarians and others. A model developed by Elizabeth Graddy, suggesting that the extent to which an occupation receives legal sanction reflects the public's perception of its social relevance, is tested. While Graddy's focus on the relationships between occupations and the public, rather on conditions within various professions, is reinforced as predicting an occupation's ability to meet the challenges of a changing society, the data from this study demonstrate more predictive variables than those identified by Graddy. A more complex view of the future of …


Regulation Of Blastocyst Formation., A J Watson, L C Barcroft May 2001

Regulation Of Blastocyst Formation., A J Watson, L C Barcroft

Obstetrics & Gynaecology Publications

Preimplantation or pre-attachment development encompasses the "free"-living period of mammalian embryogenesis, which directs development of the zygote through to the blastocyst stage. Blastocyst formation is essential for implantation, establishment of pregnancy and is a principal determinant of embryo quality prior to embryo transfer. Cavitation (blastocyst formation) is driven by the expression of specific sets of gene products that direct the acquisition of cell polarity within the trophectoderm, which is both the first epithelium of development and the outer cell layer encircling the inner cell mass of the blastocyst. Critical gene families controlling these events include: the E-cadherin-catenin cell adhesion family, …


Expression Of Pthrp And Pthr (Pth/Pthrp-R) Mrnas And Polypeptides In Bovine Ovary And Stimulation Of Bovine Blastocyst Development In Vitro Following Pthrp Treatment During Oocyte Maturation., P H Watson, M E Westhusin, A J Watson Mar 2001

Expression Of Pthrp And Pthr (Pth/Pthrp-R) Mrnas And Polypeptides In Bovine Ovary And Stimulation Of Bovine Blastocyst Development In Vitro Following Pthrp Treatment During Oocyte Maturation., P H Watson, M E Westhusin, A J Watson

Obstetrics & Gynaecology Publications

Parathyroid hormone related protein (PTHrP) and its receptor have well-established roles in the development and regulation of many tissues, including bone and mammary gland. The objectives of this study were: (1) to characterize the distribution of mRNAs encoding parathyroid hormone (PTH)-related protein (PTHrP) and receptor (PTHR) in bovine ovary; (2) to characterize the distribution of PTHrP and PTHR polypeptides in bovine ovary; (3) to examine the influences of PTHrP (1-141) treatment during bovine oocyte maturation in vitro on blastocyst development. mRNAs encoding PTHrP and PTHR were detected by in situ hybridization methods in oocytes, and granulosa cells in all follicles …


Mla In Nyc, Lisa Rae Philpott Feb 2001

Mla In Nyc, Lisa Rae Philpott

Western Libraries Publications

No abstract provided.


2001-05 Intra-Sector Mobility And Specific Inputs In Tax-Incidence Theory, Kul B. Bhatia Jan 2001

2001-05 Intra-Sector Mobility And Specific Inputs In Tax-Incidence Theory, Kul B. Bhatia

Department of Economics Research Reports

No abstract provided.


2001-04 Skidelsky's Keynes: A Review Essay, David Laidler Jan 2001

2001-04 Skidelsky's Keynes: A Review Essay, David Laidler

Department of Economics Research Reports

No abstract provided.


2001-02 Public Profit Sharing, Ronnie Schoeb Jan 2001

2001-02 Public Profit Sharing, Ronnie Schoeb

Department of Economics Research Reports

No abstract provided.


2001-12 Canadian Retirement Savings Programs And Russian Pension Reform, Joel Fried Jan 2001

2001-12 Canadian Retirement Savings Programs And Russian Pension Reform, Joel Fried

Department of Economics Research Reports

No abstract provided.


2001-11 Tax Evasion And Trust, Ronald Wintrobe Jan 2001

2001-11 Tax Evasion And Trust, Ronald Wintrobe

Department of Economics Research Reports

No abstract provided.


2001-09 The Singularity Of The Efficiency Bound Of The Mixed Proportional Hazard Model, Geert Ridder, Tiemen Woutersen Jan 2001

2001-09 The Singularity Of The Efficiency Bound Of The Mixed Proportional Hazard Model, Geert Ridder, Tiemen Woutersen

Department of Economics Research Reports

No abstract provided.


2001-10 Robustness Against Incidental Parameters And Mixing Distributions, Tiemen Woutersen Jan 2001

2001-10 Robustness Against Incidental Parameters And Mixing Distributions, Tiemen Woutersen

Department of Economics Research Reports

No abstract provided.


2001-08 Twentieth Century Monetary Regimes In Canadian Perspective, C Knick Harley Jan 2001

2001-08 Twentieth Century Monetary Regimes In Canadian Perspective, C Knick Harley

Department of Economics Research Reports

No abstract provided.


2001-06 The Role Of The History Of Economic Thought In Modern Macroeconomics, David Laidler Jan 2001

2001-06 The Role Of The History Of Economic Thought In Modern Macroeconomics, David Laidler

Department of Economics Research Reports

No abstract provided.


2001-1 Working During School And Academic Performance, Todd R. Stinebrickner, Ralph Stinebrickner Jan 2001

2001-1 Working During School And Academic Performance, Todd R. Stinebrickner, Ralph Stinebrickner

Centre for Human Capital and Productivity. CHCP Working Papers

No abstract provided.


2001-3 Peer Effects Among Students From Disadvantaged Backgrounds, Todd R. Stinebrickner, Ralph Stinebrickner Jan 2001

2001-3 Peer Effects Among Students From Disadvantaged Backgrounds, Todd R. Stinebrickner, Ralph Stinebrickner

Centre for Human Capital and Productivity. CHCP Working Papers

No abstract provided.


2001-2 Time Use And College Outcomes, Todd R. Stinebrickner, Ralph Stinebrickner Jan 2001

2001-2 Time Use And College Outcomes, Todd R. Stinebrickner, Ralph Stinebrickner

Centre for Human Capital and Productivity. CHCP Working Papers

No abstract provided.


Is Extended Volume Of External Beam Irradiation Beneficial In Post-Esophagectomy High Risk Patients Receiving Combined Chemoradiation Therapy?, E. Yu, A. R. Dar, R. Ash, G. Videtic, P. Truong, L. Stitt, A. Tomiak, M. Vincent, R. Malthaner, I. Craig, E. Brecevic, W. Kocha, R. Inculet, M. Lefcoe Jan 2001

Is Extended Volume Of External Beam Irradiation Beneficial In Post-Esophagectomy High Risk Patients Receiving Combined Chemoradiation Therapy?, E. Yu, A. R. Dar, R. Ash, G. Videtic, P. Truong, L. Stitt, A. Tomiak, M. Vincent, R. Malthaner, I. Craig, E. Brecevic, W. Kocha, R. Inculet, M. Lefcoe

Oncology Presentations

OBJECTIVE: To assess the value of extended volume irradiation with anastomotic coverage in high risk resected esophageal cancer patients.

METHOD: A retrospective study was undertaken at LRCC from 1989-1999 for high risk resected esophageal cancer patients. Adjuvant treatments consisted of 4 cycles of chemotherapy (epirubicin/fluorouracil/cisplatin or cisplatin/fluorouracil), and local regional irradiation with or without coverage of the anastomotic site. Radiation dose ranged from 45-60Gy at 1.8-2.0 Gy/fraction given with initial anterior-posterior/posterior-anterior arrangement with either extended (with anastomotic coverage) or small (without anastomotic coverage) field followed by oblique fields for boost.

RESULT: One hundred eighty-eight charts were reviewed. Seventy-two patients were …


(Re)Positioning Librarians: Young People's Views On The Information Sector, Margaret Ann Wilkinson, Roma Harris Jan 2001

(Re)Positioning Librarians: Young People's Views On The Information Sector, Margaret Ann Wilkinson, Roma Harris

Law Publications

More than 2,000 students entering their first year of university studies completed questionnaires about the work roles, future employment prospects, educational requirements, status, and starting salaries of twelve occupations. Their responses were compared with U.S. and Canadian government labor-force projections. The results revealed a complex interplay of gender relations in the students' perceptions of the occupational world and their roles within it. The results also revealed an interesting positioning of the job title "librarian" relative to other fields. Unlike their assessment of the other occupations included in the study, the students considerably underestimated the level of education required to be …


Information Sources Used By Lawyers In Problem-Solving: An Empirical Exploration, Margaret Ann Wilkinson Jan 2001

Information Sources Used By Lawyers In Problem-Solving: An Empirical Exploration, Margaret Ann Wilkinson

Law Publications

The information-seeking behavior of lawyers has not been fully investigated empirically. Prior work has tended to focus on legal research as the central task performed by lawyers in their information-seeking activities. This analysis of more than 150 interviews of practicing lawyers showed that legal research should not be considered information-seeking. The lawyers interviewed identified other tasks, such as administration of their law practices, as constituting problem-solving, information-seeking activities. In solving their problems, the lawyers overwhelmingly preferred informal sources when seeking information. In addition, they preferred sources of information internal to their organizations rather than external sources, although this was less …


Who Is Entitled To Authoritative Knowledge? Category Entitlements Of Parents And Professionals In The Literature On Children’S Literacy Learning., Pamela J. Mckenzie, Rosamund K. Stooke Jan 2001

Who Is Entitled To Authoritative Knowledge? Category Entitlements Of Parents And Professionals In The Literature On Children’S Literacy Learning., Pamela J. Mckenzie, Rosamund K. Stooke

FIMS Presentations

This paper critically analyses representations of librarians, teachers and parents in texts pertaining to children's' literacy development.