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Genetic Assessment Of Hyperuricemia And Gout In Asian, Native Hawaiian, And Pacific Islander Subgroups Of Pregnant Women: Biospecimens Repository Cross-Sectional Study, Ali Alghubayshi, Alison Edelman, Khalifa Alrajeh, Youssef Roman Jan 2022

Genetic Assessment Of Hyperuricemia And Gout In Asian, Native Hawaiian, And Pacific Islander Subgroups Of Pregnant Women: Biospecimens Repository Cross-Sectional Study, Ali Alghubayshi, Alison Edelman, Khalifa Alrajeh, Youssef Roman

Pharmacotherapy and Outcomes Science Publications

Background

Gout, an inflammatory condition, is characterized by the precipitation of monosodium urate crystals (MSU) in or around distal joints. The latter is caused by chronic hyperuricemia (HU)—high urate levels in the blood. Genetic variations in urate transporters play a significant role in determining urate levels within the human body, rendering some racial and ethnic groups more or less susceptible to developing either HU or gout. This study aims to estimate the frequencies of HU and gout risk alleles in Asian, Native Hawaiian, and Pacific Islander subgroups, using biorepository DNA samples.

Methods

The biospecimens repository at the University of Hawai’i …


Exploration Of Brookland Park And Surrounding Neighborhoods: Exploration Of Race And Space, Kearra M. Bright Jan 2022

Exploration Of Brookland Park And Surrounding Neighborhoods: Exploration Of Race And Space, Kearra M. Bright

Master of Urban and Regional Planning Capstone Projects

This project explores how race and space have impacted the neighborhoods of Brookland Park, North Barton Heights, and Providence Park from the start of their development in the 1890’s to the present day. And how systemic racism has impacted these neighborhoods over time. This paper will explore this through the history, existing conditions, findings, and policy and program recommendations. And will aid in combating systemic racism and starting the conversation about what is currently happening in some of Richmond’s Northside Neighborhoods.