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A Multi-Site, Double-Blind, Placebo-Controlled Pilot Clinical Trial To Evaluate The Efficacy Of Buspirone As A Relapse-Prevention Treatment For Cocaine Dependence, Theresa M. Winhusen, Frankie Kropp, Robert Lindblad, Antoine Douaihy, Louise Haynes, Candace Hodgkins, Karen G. Chartier

Social Work Publications

Objective—To evaluate the potential efficacy of buspirone as a relapse-prevention treatment for cocaine dependence.

Method—A randomized, double-blind, placebo-controlled, 16-week pilot trial conducted at six clinical sites between August 2012 and June 2013. Adult crack cocaine users meeting DSM-IVTR criteria for current cocaine dependence scheduled to be in inpatient/residential substance use disorder (SUD) treatment for 12–19 days when randomized, and planning to enroll in local outpatient treatment through the end of the active treatment phase were randomized to buspirone titrated to 60 mg/day (n=35) or to placebo (n=27). All participants received psychosocial treatment as usually provided by the SUD treatment programs …

Alcohol Problems In Young Adults Transitioning From Adolescence To Adulthood: The Association With Race And Gender, Karen G. Chartier, Michie N. Hesselbrock, Victor M. Hesselbrock

Social Work Publications

Race and gender may be important considerations for recognizing alcohol related problems in Black and White young adults. This study examined the prevalence and age of onset of individual alcohol problems and alcohol problem severity across race and gender subgroups from a longitudinal study of a community sample of adolescents followed into young adulthood (N = 166; 23–29 yrs. old who were drinkers). All alcohol problems examined first occurred when subjects were in their late teens and early 20s. Drinking in hazardous situations, blackouts, and tolerance were the most common reported alcohol problems. In race and gender comparisons, more …