Digital Commons Network^™

On The Hearing Of Birds, Johann Schwartzkopff

The Auk

No abstract provided.

Recent Literature, The Auk

The Auk

No abstract provided.

Multimodal Cell Complex Neural Networks For Prediction Of Multiple Drug Side Effects Severity And Frequency, Mustafa Hajij, Ghada Alzamzmi, Nina Miolane

USF Patents

A method for predicting side effects of a combination of drugs administered concurrently includes training a multi-modal cell complex neural network (MCXN) on a dataset. The MCXN includes nodes representing the drugs and proteins, pair-wise relationships between nodes representing interactions between pairs of drugs and/or proteins, and k-wise relationships between the nodes representing interactions between k drugs and/or proteins, where k¿2. The training dataset includes a list of drugs, a list of proteins, and pharmacological information about the drugs in the list of drugs and proteins in the list of proteins. A specification of the combination of at least three …

Interrelationships Among Local Values Of Wet Bulb Globe Temperature, Heat Index, And Adjusted Temperature, Andrea Giraldo

USF Tampa Graduate Theses and Dissertations

Occupational heat stress significantly affects outdoor workers who face challenges due to increased heat exposure. Because of the prevalence of heat illness, it is important to measure heat stress for outdoor workers. Monitoring occupational heat stress most often relies on the Wet Bulb Globe Temperature (WBGT) measure. Heat Index (HI) is a widely used measure to account for air temperature and humidity. Adjusted Temperature (Tadj) considers air temperature, humidity and estimates radiant heat. There is interest in predicting WBGT from HI and HI from WBGT. This study builds on previous USF research by Bernard and Iheanacho and Irvin to evaluate …

Summit Report: The Future And Ethics Of Uncrewed And Autonomous Warfare, Arman Mahmoudian

GNSI Summit Reports

On September 27-28, 2023, the Global and National Security Institute (GNSI) held the 8th Great Power Competition Conference titled “The Future and Ethics of Uncrewed and Autonomous Warfare” at the University of South Florida’s Tampa campus. As a featured event of the 2nd GNSI Tampa Summit, the conference included three major panels: “Foreign Defense Partnership in a Global Competitive Market,” “Ethical Use of Uncrewed Warfare,” and “Future of Uncrewed Systems: The Benefits and Dangers of Advancing Technology.” These panels brought together experts to discuss the evolving role of uncrewed and autonomous systems in warfare, their ethical implications, and the impact …

Knowledge Integration In Domain-Informed Machine Learning And Multi-Scale Modeling Of Nonlinear Dynamics In Complex Systems, Phat K. Huynh

USF Tampa Graduate Theses and Dissertations

Nonlinear dynamical systems have been extensively used to model various phenomena in the changing world around us, especially in science and engineering fields. Thanks to breakthrough advancements in sensing technologies, an increasingly high volume of multi-modal sensor data has been collected, which enables us gain better insights into complex systems dynamics and build sophisticated data-driven machine-learning-based dynamic models without having the access to the underlying governing equations. However, integrating domain-specific knowledge in machine learning algorithms remains pivotal for various reasons: it promises enhanced predictive accuracy, better model interpretability, and increased generalizability. This dissertation delves into three core research questions, each …

Evaluation Of Two Methods To Estimate Wet Bulb Globe Temperature From Heat Index, Stephi Pofanl

USF Tampa Graduate Theses and Dissertations

The Wet bulb globe temperature (WBGT) is a common method to evaluate environmental factors that contribute to occupational heat stress. The Heat Index (HI) is readily available as an alternative to exposure methods. They both assess the most important contributors that are air temperature and humidity. WBGT also includes radiant heat and air motion. To account for radiant heat and/or air motion, some investigators have suggested adjustments to HI. The purpose of this study is to explore two methods to estimate the usefulness of WBGT from HI.

WBGT data were collected in a variety of locations that included direct sun …

Modified Ube3a Gene For A Gene Therapy Approach For Angelman Syndrome, Kevin Ron Nash, Edwin John Weeber, Jennifer Leigh Daily

USF Patents

Angelman Syndrome (AS) is a genetic disorder occurring in approximately one in every 15,000 births. It is characterized by severe mental retardation, seizures, difficulty speaking and ataxia. The gene responsible for AS was discovered to be UBE3A and encodes for E6-AP, an ubiquitin ligase. A unique feature of this gene is that it undergoes maternal imprinting in a neuron-specific manner. In the majority of AS cases, there is a mutation or deletion in the maternally inherited UBE3A gene, although other cases are the result of uniparental disomy or mismethylation of the maternal gene. While most human disorders characterized by severe …

The Effect Of Covid- 19 Pandemic Process On Social Psychology And Nature-Based Therapeutic Activities, Aysun Yalvac, Esmahan Yalcin, Murad A. Kasalak

University of South Florida (USF) M3 Publishing

Today, many scientists have stated that the use of nature-based products and activities at certain rates together with the healing effect of modern medical techniques during the epidemic that affects the whole world has health-supporting benefits. Based on these views, people's consumption of products obtained from natural resources has increased and the interest in outdoor activities in nature has increased. Due to the positive effects of these activities on mental health, socialization and rehabilitation processes, over time, it became necessary to consider these activities within the scope of therapeutic recreation applied to groups with health restrictions such as the disabled, …

Healthcare Iot System And Network Design, Halil Ibrahim Deniz

USF Tampa Graduate Theses and Dissertations

The developing IoT concept offers many opportunities to service providers in the medical field. However, the functionality of the developed systems is increasing day by day, and it brings many different problems. One of the most important problems is the transmission of biomedical data of real-time monitoring systems to the medical server with the least delay. Network architectures are changing to meet the changing needs of densely connected devices, and “computing at the edge” is the new architectural approach emerging in IoT networks. This architecture is more dynamic than computation in the cloud because it enables data processing at each …

Functional Morphology And Taphonomy Of Ordovician–Silurian Diploporan Echinoderms, Stephen Ashley Hill

USF Tampa Graduate Theses and Dissertations

Diploporan echinoderms were one of the most speciose groups of stemmed echinoderms during the Ordovician. Despite this widespread abundance, the fossil record of diploporan fauna consists primarily of incomplete specimens, with complete specimens being rare. While the theca, or body, is more commonly preserved, the feeding appendages and the attachment structures (i.e. stems or holdfasts) are seldomly preserved. Insight into these features is highly valuable to the understanding the paleoecology, like the feeding and respiratory strategies, of these enigmatic creatures.

One group of diploporan echinoderms which does have an extensive fossil record, is the Holocystites Fauna, primarily known from the …

Crosswalking Wet Bulb Globe Temperature And Heat Index, Paul Irvin

USF Tampa Graduate Theses and Dissertations

Wet bulb globe temperature (WBGT) is a common metric to represent the environmental conditions in the assessment of heat stress. Because WBGT requires some technical expertise and sufficiently accurate equipment, there is interest in using heat index (HI) as a substitute index for the environment. Because the underlying science for understanding heat stress exposures does not exist for HI, it is necessary to crosswalk between HI and a data-driven exposure method. Expanding upon previous research, the focus of this study is the exploration of the interrelationships between WBGT and HI. The simulated weather data of Morris et. al. (2019) served …

An Ayurgenomics Approach: Prakriti-Based Drug Discovery And Development For Personalized Care, Zoufang Huang, Vivek P. Chavda, Rajashri Bezbaruah, Vladimir N. Uversky, Sucharitha Palagati, Aayushi B. Patel, Zhe-Sheng Chen

Molecular Medicine Faculty Publications

Originating in ancient India, Ayurveda is an alternative medicinal approach that provides substantial evidence for a theoretical-level analysis of all aspects of life. Unlike modern medicine, Ayurveda is based upon tridoshas (Vata, pitta, and Kapha) and Prakriti. On the other hand, the research of all the genes involved at the proteomics, metabolomics, and transcriptome levels are referred to as genomics. Geoclimatic regions (deshanupatini), familial characteristics (kulanupatini), and ethnicity (jatiprasakta) have all been shown to affect phenotypic variability. The combination of genomics with Ayurveda known as ayurgenomics provided new insights into tridosha that may pave the way for precision medicine (personalized …

Microfluidic-Coupled In Vitro Model Of The Blood-Brain Barrier, Subhra Mohapatra, Shyam S. Mohapatra, Tao Wang, Taylor Martinez

USF Patents

An in vitro microfluidic device includes a device configured to model a blood-brain barrier. The device includes a center well in fluidic communication with each of an inlet and an outlet. Each of the center well, inlet, and outlet includes a porous membrane that separates a “blood” portion (a fluid flow portion) from a “brain” portion (a fluid containing portion). The porous membrane is seeded with endothelial cells such as the human venule endothelial cells (HUVECs) on the blood side, and with astrocytes on the brain side, to accurately model the blood-brain barrier. Fluid flows between the inlet, the center …

Role Of Nhe3 In The Intestine And Thick Ascending Limb Of The Kidneys, Jianxiang Xue

USF Tampa Graduate Theses and Dissertations

The sodium-hydrogen exchanger isoform 3 (NHE3, SLC9A3) mediates most Na+/H+ exchange in the gastrointestinal tract and the kidney, where it plays crucial roles in Na+ and fluid absorption as well as acid-base homeostasis. Whole body NHE3 knockout (NHE3-/-) mice show overt absorptive defects in both the intestine and kidneys. Genetic mutations of NHE3 gene in humans are associated with congenital sodium diarrhea (CSD). In the kidneys, NHE3 is expressed in the proximal tubule (PT) and the thick ascending limb (TAL). Whole kidney-specific (PT and TAL) NHE3 knockout (NHE3Pax8cre) mice and PT-specific NHE3 knockout (PT-NHE3-/-) mice have shown the importance of …

Hyperoxia-Induced Cardiac Pathophysiology In Guinea Pig Hearts, Zain Ul Abidin

USF Tampa Graduate Theses and Dissertations

Hyperoxia, is regularly introduced to critically ill patients in ICU. Nevertheless, recent studies have shown the negative effects of this treatment on patients in critical care, including increased rates of lung and cardiac injury and thereby high in-hospital mortality. Large part of the literature related to hyperoxia was majorly focused on lung injury, with no or minimal investigations on cardiac injury. Our lab is the first to investigate the effect of hyperoxia on cardiac pathophysiology in mice and showed that mice exposed to hyperoxia for 3 days demonstrated brady-arrhythmia, cardiac hypertrophy, QTc prolongation along with other electrical remodeling and functional …

Activity-Dependent Regulation Of Extracellular Ube3a In A Novel Angelman Syndrome Rat Model, Andie Dodge

USF Tampa Graduate Theses and Dissertations

Angelman Syndrome (AS) is a rare genetic and neurologic disorder affecting approximately 1 in every 15,000 people. This disorder is characterized by seizures, absence of speech, motor and cognitive deficits, ataxia, and notably an abnormal happy demeanor with frequent smiling and laughter. A neuron-specific loss of function of the maternal allele of UBE3A, encoding for an E3 ubiquitin ligase, leads to the manifestation of AS. There are currently no cures for AS and few therapeutic options to abate symptoms. Although much investigation is required, research using the null mutation AS mouse model suggests a plausible case for pharmacological intervention.

Major …

Quantifying The Impact Of Chronic Stress On Racial Disparities In Cardiovascular Disease, Nnadozie Emechebe

USF Tampa Graduate Theses and Dissertations

Background: Despite declining mortality in cardiovascular diseases (CVD), racial disparities between non-Hispanic Blacks (NHB) and to non-Hispanic Whites (NHW) persist. Although the prevalence of traditional risk factors of CVD such as hypertension, is higher in NHB compared to NHW, adjusting for this difference does not eliminate the disparity completely. This suggests other factors might explain the persisting disparities. Thus, the purpose of this dissertation is to quantify the impact of chronic stress in explaining the racial disparities in cardiovascular diseases (CVD). This dissertation contains three studies that addressed the following Specific Aims: Specific aims: 1) To create and assess the …

Nurses And Needlesticks: Perceptions Of Stigma And Hiv Risk, Bethany Sharon Moore

USF Tampa Graduate Theses and Dissertations

Health-care providers (HCPs) are vulnerable to occupational health hazards, including dirty needle-stick injuries (DNSIs), which increase the risk for infection with HIV and other blood-borne pathogens. This study examines the perceptions of nurses and nurse practitioners who work in various health care settings regarding HIV-risk and DNSIs, in order to ascertain how these perceptions inform their decision-making regarding their health and nursing practice. I utilize a phenomenological approach to analyze the lived reality and embodiment of the DNSI experience by HCPs. The study explores the personal and institutional level factors that may influence the timely reporting and treatment of DNSIs, …

Breaking Silence: The Voices Of Syrian Refugee Children In The Canadian Classroom, Sara Shahbazi, Alyssa Palazzolo, Geri Salinitri

Journal of Global Education and Research

The researchers in the study explored the lived experiences of Syrian refugee students in the Canadian classroom. The participant sample included four students who entered their first year in a South-western Ontario public school as of the 2015-2016 calendar year. Data were collected through one-on-one semi-structured interviews. Analysis of results indicated the District’s growing need for understanding refugee students using a holistic approach, utilizing and building peer relationships for language acquisition, and recognizing the effects of the structure of the learning environment on student experiences.

Human-Skin-Inspired Adaptive Smart Textiles Capable Of Amplified Latent Heat Transfer For Thermal Comfort, Gunwoo Kim, Calvin Gardner, Kyuin Park, Ying Zhong, Sungho Jin

Mechanical Engineering Faculty Publications

Thermally adaptive textiles (TATs) enable human subjects to attain thermal comfort without energy consumption, which can lead to enormous energy savings on heating, ventilation, and air conditioning (HVAC) in buildings. Herein, TAT structures which respond to the sweat and generate pores by opening an array of flap-shaped pores patterned on the fabric surface are proposed. A moisture-driven self-actuator for flap opening by constructing a bilayer consisting of a hygroscopic layer using polyethylene glycol and cellulose acetate, and a hydrophobic polymer using a polyester type polymer, is used and successfully demonstrated an essentially instant 4 °C apparent temperature cooling performance within …

Why Covid-19 Transmission Is More Efficient And Aggressive Than Viral Transmission In Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a pandemic of coronavirus disease 2019 (COVID-19). The worldwide transmission of COVID-19 from human to human is spreading like wildfire, affecting almost every country in the world. In the past 100 years, the globe did not face a microbial pandemic similar in scale to COVID-19. Taken together, both previous outbreaks of other members of the coronavirus family (severe acute respiratory syndrome (SARS-CoV) and middle east respiratory syndrome (MERS-CoV)) did not produce even 1% of the global harm already inflicted by COVID-19. There are also four other CoVs capable of infecting humans …

Why Covid-19 Transmission Is More Efficient And Aggressive Than Viral Transmission In Previous Coronavirus Epidemics?, Fatma Elrashdy, Elrashdy M. Redwan, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a pandemic of coronavirus disease 2019 (COVID-19). The worldwide transmission of COVID-19 from human to human is spreading like wildfire, affecting almost every country in the world. In the past 100 years, the globe did not face a microbial pandemic similar in scale to COVID-19. Taken together, both previous outbreaks of other members of the coronavirus family (severe acute respiratory syndrome (SARS-CoV) and middle east respiratory syndrome (MERS-CoV)) did not produce even 1% of the global harm already inflicted by COVID-19. There are also four other CoVs capable of infecting humans …

Immune Responsive Resolvin D1 Programs Peritoneal Macrophages And Cardiac Fibroblast Phenotypes In Diversified Metabolic Microenvironment, Vasundhara Kain, Ganesh V. Halade

Internal Medicine Faculty Publications

Bioactive lipid mediators derived from n-3 and n-6 fatty acids are known to modulate leukocytes. Metabolic transformation of essential fatty acids to endogenous bioactive molecules plays a major role in human health. Here we tested the potential of substrates; linoleic acid (LA) and docosahexaenoic acid (DHA) and their bioactive products; resolvin D1 (RvD1) and 12- S-hydroxyeicosatetraenoic acids (HETE) to modulate macrophage plasticity and cardiac fibroblast phenotype in presence or absence of lipid metabolizing enzyme 12/15-lipoxygenase (LOX). Peritoneal macrophages and cardiac fibroblasts were isolated from wild-type (C57BL/6J) and 12/15LOX −/− mice and treated with DHA, LA, 12(S)-HETE, and RvD1 for 4, …

Pretreatment Of Carprofen Impaired Initiation Of Inflammatory- And Overlapping Resolution Response And Promoted Cardiorenal Syndrome In Heart Failure, Veena Krishnan, David Booker, Gabrielle Cunningham, Jeevan Kumar Jadapalli, Vasundhara Kain, Amanda B. Pullen, Ganesh V. Halade

Internal Medicine Faculty Publications

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are commonly used to control pain, inflammation, and limit the cardinal signs of injury in humans. However, prolonged use of NSAIDs increases the risk of heart attack (myocardial infarction; MI) and the subsequent risk of heart and renal failure. The molecular and cellular mechanism of action for this adverse effect, particularly along the cardiorenal network, is incomplete. To define the mechanism, carprofen (CAP), an NSAID was administered at the dose of 5 mg/kg to C57BL/6 male mice for two weeks. After last dose of CAP treatment mice were subjected to permanent occlusion of coronary artery that …

Structure Determination By Single-Particle Cryo-Electron Microscopy: Only The Sky (And Intrinsic Disorder) Is The Limit, Emeka Nwanochie, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Traditionally, X-ray crystallography and NMR spectroscopy represent major workhorses of structural biologists, with the lion share of protein structures reported in protein data bank (PDB) being generated by these powerful techniques. Despite their wide utilization in protein structure determination, these two techniques have logical limitations, with X-ray crystallography being unsuitable for the analysis of highly dynamic structures and with NMR spectroscopy being restricted to the analysis of relatively small proteins. In recent years, we have witnessed an explosive development of the techniques based on Cryo-electron microscopy (Cryo-EM) for structural characterization of biological molecules. In fact, single-particle Cryo-EM is a special …

Leaders Who Learn: The Intersection Of Behavioral Science, Adult Learning And Leadership, Natalya I. Sabga

USF Tampa Graduate Theses and Dissertations

This study examines if a relationship exists among three rich research streams, specifically the behavioral science of motivation, adult learning and leadership. What motivates adult professionals to continue learning and how is that connected to their style and efficacy as leaders? An extension of literature to connect Andragogy, Self-determination and Transformational Leadership Theory is explored. Responses to questions adapted from the Carré Model of Adult Orientation and Implication on Learning and Training Activities (Carré, 1997) and the Multifactor Leadership Questionnaire (Avolio & Bass, 2000) are compared among a sample of adult professionals in leadership positions. Results indicate that learning motivation …

Educating Dídac: Mankind’S New Father And The End Of Patriarchy In Manuel De Pedrolo’S "Typescript Of The Second Origin", Sara Martín

Alambique. Revista académica de ciencia ficción y fantasía / Jornal acadêmico de ficção científica e fantasía

The post-apocalyptic novel by Catalan writer Manuel de Pedrolo, Typescript of the Second Origin (1974, English 2017) celebrates Alba as humankind’s new mother. Alba’s mission, however, clearly depends on the help of a man willing to father her children, a role for which Pedrolo made an extremely singular choice: whereas Alba is already 14 when Typescript begins, Dídac is just a 9-year-old boy. Because of the exceptional situation (the catastrophic extraterrestrial devastation of Earth), Pedrolo forces Dídac to mature very fast, to the point that he is only 12 when Alba gives birth to their baby. Additionally, Dídac’s mixed-raced genetic …

A New Genus For Cirolana Troglexuma Botosaneanu & Iliffe, 1997, An Anchialine Cave Dwelling Cirolanid Isopod (Crustacea, Isopoda, Cirolanidae) From The Bahamas, Niel L. Bruce, Saskia Brix, Nicholas Balfour

KIP Articles

Cirolana troglexuma Botosaneanu & Iliffe, 1997 is redescribed and a Lucayalana Bruce & Brix, gen. n. established for the species. In total 38 specimens were collected from Hatchet Bay Cave, Eleuthera. Specimens on which previous records of L. troglexuma (from Exuma Cays, Cat Island, and Eleuthera) were based have been re-examined when possible. The diagnostic identifying characters and purported apomorphies for Lucayalana gen. n. are: frontal lamina short, narrow, less than 7% width of labrum, not extending to anterior margin of head; pleonite 3 extending posteriorly to posterior of pleonite 5, laterally overlapping pleonites 4 and 5; ventrally broad, forming …

Stable Isotope Analysis Of The Dietary Habits Of A Greek Community In Archaic Syracuse (Sicily): A Pilot Study, Davide Tanasi, Robert Tykot, Andrea Vianello, Stephan Hassam

History Faculty Publications

The study and reconstruction of ancient dietary habits has become a very significant topic in archaeological research. Most chemical analysis studies for diet at Greek sites are limited to prehistory, with very few examples of studies for the Classical period. This paper represents a pilot study of stable isotope analysis carried out on a group of 15 individuals selected among the population interred in the Archaic necropolis of Scala Greca at Syracuse (Sicily), a cemetery discovered in 2010-2011. Based on the funerary assemblages and certain features such as shape, dimensions, coverage system and architectural features, a preliminary distinction has been …