Digital Commons Network^™

Does Better A1c Control Worsen Osteoarthritis? An Electronic Health Record Cross-Sectional Study, Sarah C. Cattaneo

USF Tampa Graduate Theses and Dissertations

Obesity is a major risk factor for osteoarthritis (OA). There is evidence that diabetes also increases risk. Our hypothesis is that A1C is a predictor of OA severity. The aim is to investigate the association between A1C, BMI, and knee and hip OA severity. This is a cross-sectional study within the Veterans Health Administration (VHA) database containing 818 patients with diagnosed diabetes. Patients at one VHA facility with recorded diabetes in fiscal year 2020 were identified. A1C and BMI data was obtained from the electronic health record. Chart reviews were performed to collect data on imaging reports of weight-bearing joints …

Evaluating Public Posting, Goal Setting, And Rewards To Increase Physical Activity In Children, Bryon G. Miller

USF Tampa Graduate Theses and Dissertations

In Experiments 1 and 2 we evaluated a pedometer-based intervention consisting of public posting between two teams of students, with additional self-monitoring, goal setting, and reinforcement components, to increase physical activity during school recess. In the absence of self-monitoring, performance feedback alone did not increase physical activity levels above those observed during baseline. Additionally, higher levels of physical activity were observed when goal-setting was introduced, with the highest levels of activity observed when raffle tickets could be earned for exceeding a specified step-total goal. In Experiment 3 we removed the team component and evaluated similar intervention components across an entire …

The Tampa Gym Study: An Ethnographic Exploration Of Gyms, Female Gym-Goers And The Quest For Fitness In Tampa, Fl, Danielle Reneé Rosen

USF Tampa Graduate Theses and Dissertations

The Tampa Gym Study was an ethnographic examination of veteran women exercisers, their workout routines, and their attitudes towards the workouts that they undertake in two Tampa area gyms. The study’s principle objective was to study “fitness culture” in these facilities and the manner in which that culture is embodied in the language women use to describe themselves and their exercise behaviors.

The obesity crisis in the United States has been significantly responsible for an increase in membership in gyms and fitness facilities nationwide. The “culture of fitness” as it is embodied in these facilities has impacted women and their …

Predicting Weight Loss Following Bariatric Surgery: The Impact Of Stress, Depression, Social Support And Patient Gender, Erica Ahlich

USF Tampa Graduate Theses and Dissertations

The buffering effect of social support against a range of stress-related health outcomes has been well-documented in a variety of research areas; however, no previous work has examined the applicability of this model to bariatric surgery outcomes. Additionally, based on previous evidence and relevant theoretical work, the stress-buffering effect of social support may show important gender differences. The current study examined stress, depression, social support, and patient gender as predictors of curvilinear weight loss trajectories during the first year following surgery. Data were collected using retrospective chart review. The buffering effects of three types of support were explored using growth …

Links Between Iron And Lipids: Implications In Some Major Human Diseases, Stephanie Rockfield, Ravneet Chhabra, Michelle Robertson, Nabila Rehman, Richa Bisht, Meera Nanjundan

Molecular Biosciences Faculty Publications

Maintenance of iron homeostasis is critical to cellular health as both its excess and insufficiency are detrimental. Likewise, lipids, which are essential components of cellular membranes and signaling mediators, must also be tightly regulated to hinder disease progression. Recent research, using a myriad of model organisms, as well as data from clinical studies, has revealed links between these two metabolic pathways, but the mechanisms behind these interactions and the role these have in the progression of human diseases remains unclear. In this review, we summarize literature describing cross-talk between iron and lipid pathways, including alterations in cholesterol, sphingolipid, and lipid …

Mobility And Vitality Lifestyle Program (Move Up): A Community Health Worker Intervention For Older Adults With Obesity To Improve Weight, Health, And Physical Function, Elizabeth M. Venditti, Janice C. Zgibor, Joni Vander Bilt, Lori A. Kieffer, Robert M. Boudreau, Lora E. Burke, Nancy W. Glynn, John M. Jakicic, Kenneth J. Smith

Epidemiology and Biostatistics Faculty Publications

Background and Objectives: Obesity rates in adults ≥65 years have increased more than other age groups in the last decade, elevating risk for chronic disease and poor physical function, particularly in underserved racial and ethnic minorities. Effective, sustainable lifestyle interventions are needed to help community-based older adults prevent or delay mobility disability. Design, baseline recruitment, and implementation features of the Mobility and Vitality Lifestyle Program (MOVE UP) study are reported.

Research Design and Methods: MOVE UP aimed to recruit 26 intervention sites in underserved areas around Allegheny County, Pennsylvania and train a similar number of community health workers to deliver …

The Role Of Craving In Emotional And Uncontrolled Eating, Christina L. Verzijl, Erica Ahlich, Robert C. Schlauch, Diana Rancourt

Psychology Faculty Publications

This study presents a novel application of the cognitive processing model of alcohol craving (CPMA) from the addictions field to the role of food craving in the well-established restrained eating–overeating relationship associated with binge eating disorder (BED). A community sample (N = 1058, ages 18-66) completed an online survey assessing four core domains: restrained eating, trait food craving, uncontrolled eating, and emotional eating. In accordance with the CPMA, food craving emerged as a significant indirect effect of the association between restrained eating and both uncontrolled and emotional eating. Gender did not significantly moderate any direct or indirect associations, suggesting that …

Impact Of Obesity And Expression Of Obesity-Related Genes In The Progression Of Prostate Cancer In African American Men, Mmadili Nancy Ilozumba

USF Tampa Graduate Theses and Dissertations

In the US, the incidence and mortality rates of prostate cancer (PCa) are higher among African American men compared to European American men. Obesity is an important risk factor of PCa. Obesity is known to alter the gene expression profiles in prostate tumors. This study evaluates the impact of obesity and the expression of obesity-related genes on the progression of PCa in African American men.

The primary outcome of interest is biochemical recurrence (BCR) of PCa. There were 48 African American prostate cancer patients in the study. The tissue samples included 42 normal tissues, 40 Prostate Intraepithelial Neoplasia (PIN) and …

Evaluating The Effectiveness Of Goal Setting And Textual Feedback Using A Wearable Technology For Increasing Running Distance, Michael Zarate

USF Tampa Graduate Theses and Dissertations

Obesity is a growing problem that has life-threatening health consequences. One way to combat obesity is by increasing physical activity levels, which has been a focus of recent applied behavioral research. The purpose of this study was to evaluate the effectiveness of goal setting and textual feedback without social support to increase physical activity, specifically weekly running distance. A multiple-baseline across participants design was employed with four participants using a Fitbit Flex accelerometer to collect two physical activity measures, intense steps and distance. Results showed a significant increase in weekly running distance for two out of four participants following the …

Modified Qigong Breathing Exercise For Reducing The Sense Of Hunger On An Empty Stomach, Alexander P. Voroshilov, Alex A. Volinsky, Zhixin Wang, Elena V. Marchenko

Mechanical Engineering Faculty Publications

Background: The aims of this study were to determine whether a modified Qigong breathing exercise can reduce the sense of hunger and identify possible mechanisms.

Methods: The results from the test group, which performed the exercise, are compared with the control group, which performed deep breathing. Intestinal pressure measurements, stomach pH monitoring, and participant surveys were used for assessment.

Results: Stomach pH was increased by 3 (0.2) and intestinal pressure was reduced by 12 (0.5) mm Hg in the experimental group and did not change significantly in the control group. The study provides strong evidence that the exercise can significantly …

An Exploration Of Adolescent Obesity Determinants, Anastasia King Smith

USF Tampa Graduate Theses and Dissertations

In 2010, approximately two-thirds of adults and one-fifth of the adolescent population in the United States were considered either overweight or obese, resulting in the United States having the highest per capita obesity rate among all OECD countries. A considerable body of literature regarding health behavior, health outcomes, and public policy exists on what the Centers for Disease Control and Prevention considers an obesity epidemic. In response to the growing problem of childhood obesity, the Child Nutrition and WIC Reauthorization Act of 2004 (CNRA), which required that schools participating in the National School Lunch Program and/or School Breakfast Program have …

Anti-Fat Attitudes And Weight Bias Internalization: An Investigation Of How Bmi Impacts Perceptions, Opinions And Attitudes, Laurie Schrider

USF Tampa Graduate Theses and Dissertations

Americans hold negative and judgmental attitudes towards obese and overweight individuals and these anti-fat attitudes and weight stigma have become a damaging form of discrimination. The internalization of weight bias and anti-fat attitudes contributes to negative health outcomes including: feelings of devalue, self-hate, anxiety, depression, body dissatisfaction and eating disturbances. The purpose of this study was to investigate weight bias internalization in individuals who perceive themselves as overweight as well as to examine differences in anti-fat attitudes among normal and overweight individuals. A sample of 202 male and females completed an online survey that assessed anti-fat attitudes via the Anti-Fat …

The Effects Of Parent-Adolescent Communication And Parenting Style On The Physical Activity And Dietary Behaviors Of Latino Adolescents, Dianna Mary Boone

USF Tampa Graduate Theses and Dissertations

The obesity epidemic among children and adolescents has been growing rapidly over the past 10 years, particularly in Latino children. Multiple researchers have found support for positive associations between parent-child communication and healthy nutrition and exercise behaviors. The present study examined the relations between parent-adolescent communication and parenting style and the dietary and exercise behaviors of Latino adolescents. The study included 79 adolescents between the ages of 13 and 18 years and their parents (100% are Latino). Correlation and hierarchical regression analyses were conducted to determine which parenting style and communication variables are significantly associated with adolescents’ dietary and physical …

Intrinsic Disorder In Biomarkers Of Insulin Resistance, Hypoadiponectinemia, And Endothelial Dysfunction Among The Type 2 Diabetic Patients, Osama H. Jiffri, Fadwa M. Al-Sharif, Essam H. Jiffri, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Type 2 diabetes mellitus (T2DM) is a chronic and progressive disease that is strongly associated with the all-cause and cardiovascular mortality. The present study aimed to analyze the abundance and functionality of intrinsically disordered regions in several biomarkers of insulin resistance, adiponectin, and endothelial dysfunction found in the T2DM patients. In fact, in comparison to controls, obese T2DM patients are known to have significantly higher levels of inter-cellular adhesion molecule (iCAM-1), vascular cell adhesion molecule (vCAM-1), and E-selectin, whereas their adiponectin levels are relatively low. Bioinformatics analysis revealed that these selected biomarkers (iCAM-1, vCAM-1, E-selectin, and adiponectin) are characterized by …

Intrinsic Disorder In Biomarkers Of Insulin Resistance, Hypoadiponectinemia, And Endothelial Dysfunction Among The Type 2 Diabetic Patients, Osama H. Jiffri, Fadwa M. Al-Sharif, Essam H. Jiffri, Vladimir N. Uversky

Molecular Medicine Faculty Publications

Type 2 diabetes mellitus (T2DM) is a chronic and progressive disease that is strongly associated with the all-cause and cardiovascular mortality. The present study aimed to analyze the abundance and functionality of intrinsically disordered regions in several biomarkers of insulin resistance, adiponectin, and endothelial dysfunction found in the T2DM patients. In fact, in comparison to controls, obese T2DM patients are known to have significantly higher levels of inter-cellular adhesion molecule (iCAM-1), vascular cell adhesion molecule (vCAM-1), and E-selectin, whereas their adiponectin levels are relatively low. Bioinformatics analysis revealed that these selected biomarkers (iCAM-1, vCAM-1, E-selectin, and adiponectin) are characterized by …

Obesity As A Disease: Effects On Weight-Biased Attitudes And Beliefs, Rheanna Nichole Ata

USF Tampa Graduate Theses and Dissertations

In June 2013, the American Medical Association (AMA) made the highly controversial decision to designate obesity a disease. Proponents predicted the decision would lead to reduced weight-related stigma, whereas opponents predicted designating a third of the population as “diseased” would exacerbate stigma. To determine the effects of defining obesity as a disease on explicit and implicit weight-biased attitudes and explicit weight-biased beliefs, female undergraduate students (N = 146) were randomly assigned to one of two groups: disease or lifestyle. Participants in the disease group (n = 71) were asked to read an article describing obesity as a disease caused by …

Effects Of A Brief Relaxation Intervention On Stress-Related Eating, Laura Lynn Mayhew-Purcell

USF Tampa Graduate Theses and Dissertations

The experience of stress may contribute to increased food consumption and selection of unhealthy food options. Resource depletion theory suggests stress temporarily depletes resources needed to regulate behavior. Depletions of self-control may result in subsequent failure to regulate eating behaviors, which is particularly salient in restrained eaters. Restraint theory posits people high in dietary restraint require significant effort to control eating. Emotional eating theory further suggests palatable foods may be used to regulate emotional stress reactions. Relaxation exercises to mitigate stress reactions are recommended in eating and weight management programs, but lack quality scientific support. The current study examined the …

Obesity And Dining Out: An Exploration Of Dietary Trends In Urban Malaysia, Sylvia S. Lim

USF Tampa Graduate Theses and Dissertations

Economic growth has spurred rapid urbanization in Malaysia and triggered changes in diet, lifestyle, and disease trends. National studies show that a third of Malaysia's population is overweight/obese while household expenditures on dining out grow. In metropolitan Kuala Lumpur (KL), residents navigate concepts of nutrition, body weight, and health as they dine out. Using the biocultural framework, this study examined links between body weight, diet, income, street food consumption, and nutritional knowledge through the perspectives of consumers and vendors. Altogether, 77 participants were recruited for this three-phase research. In the first phase, a survey was administered to 60 participants recruited …

Evaluation Of The Interest In Development And Availability Of The Resting Metabolic Rate Test As A Routine Healthcare Standard, Seth Wayne Parrish

USF Tampa Graduate Theses and Dissertations

Introduction: A growing worldwide pandemic exists today that has large implications for the future of healthcare among the nations. Obesity is a growing disease that has multiple

implications for morbidity and mortality including cardiovascular disease, stroke and diabetes. The obese and overweight population plagues nearly 46% of the world's population, and likely is

preventable. We wanted to examine what role metabolic testing could play in prevention.

Methods: A cross-sectional study composed of a 52-question Likert-based scale survey was constructed and distributed to healthcare providers. We hypothesized that there would be a

generally accepted interest in establishing routine metabolic rate testing …

Obese And Diabetic Kkay Mice Show Increased Mortality But Improved Cardiac Function Following Myocardial Infarction, James R. Heaberlin, Yonggang Ma, Jianhua Zhang, Seema S. Ahuja, Merry L. Lindsey, Ganesh V. Halade

Internal Medicine Faculty Publications

Background: Introduction of the yellow obese gene (Ay) into mice (KKAy) results in obesity and diabetes by 5 weeks of age. Methods: Using this model of type 2 diabetes, we evaluated male and female 6-to 8-month-old wild-type (WT, n=10) and KKAy (n=22) mice subjected to myocardial infarction (MI) and sacrificed at day (d) 7. Results: Despite similar infarct sizes (50%±4% for WT and 49%±2% for KKAy, P=not significant), the 7d post-MI survival was 70% (n=7/10) in WT mice and 45% (n=10/22) in KKAy mice (P < .05). Plasma glucose levels were 1.4-fold increased in KKAy mice at baseline compared to WT (P < .05). Glucose levels did not change in WT mice but decreased 38% in KKAy post-MI (P < .05). End-diastolic and end-systolic dimensions post-MI were smaller and fractional shortening improved in the KKAy (5%±1% in WT and 10%±2% in KKAy, P < .05 for all). The improved cardiac function in KKAy was accompanied by reduced macrophage numbers and collagen I and III levels (both P < .05). Griffonia (Bandeiraea) simplicifolia lectin-I staining for vessel density demonstrated fewer vessels in KKAy infarcts (5.9%±0.5%) compared to WT infarcts (7.3%±0.1%, P < .05). Conclusion: In conclusion, our study in KKAy mice revealed a paradoxical reduced post-MI survival but improved cardiac function through reduced inflammation, extracellular matrix accumulation, and neovascularization in the infarct region. These results indicate a dual-role effect of obesity in the post-MI response.

The Strong Black Woman, Depression, And Emotional Eating, Michelle Renee Offutt

USF Tampa Graduate Theses and Dissertations

Abstract

Eighty percent of all black women are overweight or obese which can lead to greatly increased morbidity and mortality, increasing healthcare costs and loss of healthy years of life. While multiple factors may contribute to obesity in black women, the cultural persona of the Strong Black Woman (SBW), an ideology that promotes unflagging toughness and denial of self-needs, may be the basis for behaviors that contribute to steady state obesity in this group. The purpose of this study was to investigate the relationships between the SBW persona, depression, and emotional eating.

Two predominately black churches in Florida were approached …

Evaluating The Effectiveness Of An Internet-Based Behavioral Program For Increasing Physical Activity With And Without A Behavioral Coach, Diego Alejandro Valbuena

USF Tampa Graduate Theses and Dissertations

Obesity is a problem of vast social concern in the United States. One factor that has been linked to reduction in body fat and the health problems associated with obesity is increasing physical activity. Although in-person behavioral interventions have been shown effective at increasing physical activity, attention is now being placed on disseminating these interventions through the use of technology. Several internet-based interventions have been developed and are readily available. The purpose of this study was to evaluate "Fitbit," a web-based behavioral intervention for increasing physical activity and losing weight. Additionally, this study examined if the addition of contact from …

The Relationship Between Socioeconomic Status And Body Mass Index On Vitamin D Levels In African American Women With And Without Diabetes Living In Areas With Abundant Sunshine, Shani Vann Davis

USF Tampa Graduate Theses and Dissertations

OBJECTIVE: To examine the relationships between socioeconomic status (SES), body mass index (BMI), and vitamin D levels in African American (AA) women living in areas with abundant sunshine; and to explore if diabetes moderates these relationships.

SIGNIFICANCE: More AA's live in poverty, and experience obesity, diabetes, and chronic disease compared to other groups. Eighty percent of AA women are overweight or obese, and rates of type 2 diabetes is highest in this group. Minority race, obesity, and diabetes increase risks for low vitamin D, and are associated with p

DESIGN AND METHOD: A cross-sectional descriptive research design was used to …

Perceptual Responses To High-Intensity Interval Training In Overweight And Sedentary Individuals, Nicholas Martinez

USF Tampa Graduate Theses and Dissertations

Contemporary aerobic exercise guidelines comprised of continuous durations and higher intensities have been shown to be effective in the prevention and treatment of risk factors associated with obesity and cardiovascular disease (CVD). However, high-intensity interval training (HIIT) has recently been examined as an advantageous protocol for producing more favorable physiological and psychological benefits in comparison to traditional continuous exercise guidelines. The dual-mode model, which examines the dose response relationship between exercise intensity and affective valence, would suggest that exercise performed well above the ventilatory threshold (VT) in the severe domain should result in negative affective valence.

Numerous investigations have confirmed …

Dha Derivatives Of Fish Oil As Dietary Supplements: A Nutrition-Based Drug Discovery Approach For Therapies To Prevent Metabolic Cardiotoxicity, Yonggang Ma, Merry L. Lindsey, Ganesh V. Halade

Internal Medicine Faculty Publications

Introduction: During the early 1970s, Danish physicians Jorn Dyerberg and colleagues observed that Greenland Eskimos consuming fatty fishes exhibited low incidences of heart disease. Fish oil is now one of the most commonly consumed dietary supplements. In 2004, concentrated fish oil was approved as a drug by the FDA for the treatment of hyperlipidemia. Fish oil contains two major omega-3 fatty acids: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). With advancements in lipid concentration and purification techniques, EPA- or DHA-enriched products are now commercially available, and the availability of these components in isolation allows their individual effects to be examined. …

Combination Of Conjugated Linoleic Acid With Fish Oil Prevents Age-Associated Bone Marrow Adiposity In C57bl/6j Mice, Ganesh V. Halade, Md M. Rahman, Paul J. Williams, Gabriel Fernandes

Internal Medicine Faculty Publications

The inverse relationship between fat in bone marrow and bone mass in the skeleton of aging subjects is well known. However, there is no precise therapy for the treatment of bone marrow adiposity. We investigated the ability of conjugated linoleic acid (CLA) and fish oil (FO), alone or in combination, to modulate bone loss using 12 months old C57Bl/6J mice fed 10% corn oil diet as control or supplemented with 0.5% CLA or 5% FO or 0.5% CLA+5% FO for 6 months. We found, CLA-fed mice exhibited reduced body weight, body fat mass (BFM) and enhanced hind leg lean mass …

Obesity-Mediated Inflammatory Microenvironment Stimulates Osteoclastogenesis And Bone Loss In Mice, Ganesh V. Halade, Amina El Jamali, Paul J. Williams, Roberto J. Fajardo, Gabriel Fernandes

Internal Medicine Faculty Publications

Clinical evidence indicates that fat is inversely proportional to bone mass in elderly obese women. However, it remains unclear whether obesity accelerates bone loss. In this report we present evidence that increased visceral fat leads to inflammation and subsequent bone loss in 12-month-old C57BL/6J mice that were fed 10% corn oil (CO)-based diet and a control lab chow (LC) for 6. months. As expected from our previous work, CO-fed mice demonstrated increased visceral fat and enhanced total body fat mass compared to LC. The adipocyte-specific PPARγ and bone marrow (BM) adiposity were increased in CO-fed mice. In correlation with those …

Food Deserts' And 'Food Swamps' In Hillsborough County, Florida: Unequal Access To Supermarkets And Fast-Food Restaurants, Dana Beth Stein

USF Tampa Graduate Theses and Dissertations

Research has shown that the suburbanization of supermarkets has created `food deserts', defined as areas where socially disadvantaged individuals lack access to nutritious food outlets. Additionally, the growing presence of fast-food restaurants has created `food swamps', or areas where socially disadvantaged individuals encounter an overabundance of unhealthy food outlets. While previous studies have analyzed either `food deserts' or `food swamps' using conventional statistical techniques, a more comprehensive approach that includes samples of both healthy and unhealthy entities and considers the variety of available food options is necessary to improve our understanding of the local food environment and related disparities.

This …

Evaluating The Get Into Fitness Today (Gift) Program: Weight Loss And The Roles Of Education And Empowerment, Emily Koby Novicki

USF Tampa Graduate Theses and Dissertations

This study investigated the effects of Get Into Fitness Today (GIFT), a health program for adults that promotes balanced nutrition, physical activity, and weight loss through weekly meetings that provide education and social support. In addition to investigating the effects of GIFT, this evaluation sought to better understand explanatory models used by participants and program staff, and the roles of education and empowerment in weight loss and health education. This mixed methods, case study evaluation consisted of quantitative analysis of existing program records for 664 participants, 40 hours of participant observation of class sessions with ten GIFT groups, and follow-up …

High Fat Diet-Induced Animal Model Of Age-Associated Obesity And Osteoporosis, Ganesh V. Halade, Md M. Rahman, Paul J. Williams, Gabriel Fernandes

Internal Medicine Faculty Publications

Osteoporosis and obesity remain a major public health concern through its associated fragility and fractures. Several animal models for the study of osteoporotic bone loss, such as ovariectomy (OVX) and denervation, require unique surgical skills and expensive set up. The challenging aspect of these age-associated diseases is that no single animal model exactly mimics the progression of these human-specific chronic conditions. Accordingly, to develop a simple and novel model of post menopausal bone loss with obesity, we fed either a high fat diet containing 10% corn oil (CO) or standard rodent lab chow (LC) to 12-month-old female C57Bl/6J mice for …