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Improving Diabetes Self-Management Through A Partnership Between Clinical Providers And Community Educators In Appalachian Communities, Soghra Jarvandi, Lydia Hoskins, Karen Carver, Andrew May

Journal of Appalachian Health

Introduction: The burden of diabetes is an increasing public health challenge, especially in the Appalachian Region.

Purpose: This study assessed the impact of a community-based diabetes education program on glycemic control.

Methods: Health Extension for Diabetes (HED) is a 4-month diabetes education program offered by Extension educators in collaboration with clinical providers. Participants’ data were collected via phone interviews at baseline and after completing the program. Assessments included self-reported HbA1c, socio-demographics, diabetes knowledge, self-efficacy, and self-management behaviors. Data were analyzed by SAS software using paired analyses.

Results: Of the 105 participants in the program, 87 (83%) completed the post-assessment. Among …

History And Tradition Of Inequality, Advocacy, And Progress, Teri Dobbins Baxter

Kentucky Law Journal

No abstract provided.

Rural/Urban Disparities In Utilization Of Diabetes Self-Management Training (Dsmt) To The Fee-For-Service Medicare Population, 2017–2024, Wanying Zhu, Aleksandr Taraskin, Jeffrerey Talbert

Rural & Underserved Health Research Center Publications

Key Report Highlights

• A significant rural DSMT access gap exists. Rural beneficiaries accounted for 20.1% of Medicare beneficiaries with diabetes but only 7.8% of DSMT participants.

• Geographic availability remains limited. Only 16.8% of counties with DSMT utilization were rural.

• Access, not demand, appears to be the primary challenge. Rural counties offering DSMT achieved utilization rates more than twice those observed in urban counties (6.0% vs. 2.5%).

• Expanding rural DSMT capacity may represent a high-impact opportunity to improve diabetes self-management support among underserved Medicare beneficiaries.

Cellular Senescence Links Muscle Atrophy And Posttraumatic Osteoarthritis After Acl Injury, Alexander R. Keeble, Allison Owen, Sara Gonzalez-Velez, Nicholas T. Thomas, Camille R. Brightwell, Peyton J. Balawender, Madeline G. O'Daniel, Helena C. Weiss, Haley Noehren, Heather Thompson, Karen Sofia Zuluaga-Osorio, Zane T. Bates, Lauren Gottlieb, Douglas E. Long, Douglas Harrison, Philip Kern, Caitlin E. Conley, Michael A. Samaan, Stephen Duncan, Austin Stone, Darren Johnson, Yuan Wen, Brian Noehren, Cory Dungan, Christopher Fry

Biology Faculty Publications

Traumatic knee injury leads to posttraumatic osteoarthritis (PTOA) and significant skeletal muscle weakness, resulting in chronic disability. The current standard of care frequently fails to prevent musculoskeletal dysfunction, underscoring the need to identify therapeutic mechanisms of PTOA. Using an established preclinical anterior cruciate ligament (ACL) transection model of PTOA and leveraging an innovative SPiDER-senescence-associated β-galactosidase stain to discern senescent cells, we investigated cellular senescence at single-cell resolution and identified anti-inflammatory macrophages as a predominant contributor to the senescent cell burden in both muscle and knee joint after injury. Clearance of senescent cells using the senolytic dasatinib and quercetin (D + …

The Effect Of Addition Of Formic Acid, With Or Without Formalin, On The Conservation Quality, Digestibility, Nutritive Value, And Nitrogen Balance Of Direct-Cut Silage, C Demarquilly, Elisabeth Grenet, J P. Dulphy

IGC Proceedings (1977-2023)

From 34 standing crops of grasses or legumes, 93 direct-cut silages were prepared: 33 without additive, 37 with formic acid (3.5 or 5 1/t), 10 with formic acid and 1.5 1/t formalin, 15 with formic acid and 3.5 to 5 1/t formalin. The conservation quality of the silages was improved by the addition of formic acid and even further by the mixture of formic acid and formalin. Silage digestibility is similar to that of the corresponding green forage, but the addi­tion of formalin considerably reduces protein digestibility (by 2 to 8 points). The voluntary intake of silage is lower than …

The Effects Of Mixtures Of Formalin And Acid On Silage Fermentation, Robert F. Wilson, Roger J. Wilkins

IGC Proceedings (1977-2023)

Three experiments are described in which herbages were ensiled in test-tube silos without additive or after the addition of mixtures containing formalin with formic, sulphuric or phosphoric acid in order to restrict fermen­tation in the silo. Silages containing less than 5 % of the dry matter as fermentation acids and with low contents of ammonia were pro­duced with mixtures containing either 0.1 % of the fresh crop weight as formaldehyde with 10 meq of formic or sulphuric acid/ 100 g of crop or with 0.2 % of formaldehyde with 5 meq of either acid. Phosphoric acid was less effective than …

Effect Of Zinc, Copper, Molybdenum And Cobalt On Develop­ Ment, Yield And Hay Quality Of Lucerne, B Miskovic, P Eric, M Pantovic

IGC Proceedings (1977-2023)

The effect of zinc, copper, molybdenum and cobalt exerted on the development, yield and quality of various cultivated plants is favourable in many ways. Our studies of their application in the nutrition of luceme in a pot experiment and field trials on chernozem soil were carried out to determine the effect of the above micro­elements on the yield, development and quality of lucerne hay, when applied togeµier with NPK fertilizers. The results of our experiments have shown that the application of these microelements, especially of zinc and copper, together with NPK fertilizers resulted in considerable increase of lucerne hay yields …

Influence Of Mineral Fertilization On The Quality Of Meadow Grasses, A Klesnil, F Turek

IGC Proceedings (1977-2023)

The effect of different rates of nitrogen fertili­zation combined with PK on the quality of 6 important meadow grasses (Dactylis glomerata, Poa pratensis, Holcus lanatus, Trisetum jla­vescens, Alopecurus pratensis, and Deschampsia caespitosa) was studied from 1973 to 1975. Complete NPK nutrition at rates of I 00 and 100 + 50 kg N/ha distinctly increased the di­gestible crude protein content in the tested grasses, especially in the first cut (in Dactylis glomerata by 44-56 %, in Poa pratensis by 54 %, and in Trisetum jlavescens by 35 %). Application of 50 kg N/ha after the first cut produced maximum increase of …

Experiments About The Nutrition Of Grassland Ecosystems With Respect To Different Times Of Npk Application, Eduard Halva, Josef Lesak

IGC Proceedings (1977-2023)

Experiments carried out during the years 1971 to 1973 have shown that a uniform system of the nutrition of grassland associations cannot be introduced into all production areas and all types of forage crops represented in Czechoslo­vakia. In relation to the complexity of the studied problems and to the diversity of soil and climatic conditions in the production areas, it is necessary to propose the adequate systems of nutrition after several series of experiments or to base them on empirical experience drawn from the studied production area. The testing of different times of application of identical nutrient rates (150 kg …

Problems Of Nitrogen Nutrition Of Medicago Sativa L. With Respect To Rhizobia, Eduard Halva, Josef Lesak

IGC Proceedings (1977-2023)

The effect of increasing rates of nitrogen (80, 140, 200, 260, and 320 kg/ha) on the yields of above-ground biomass and nutrients in alfalfa was studied in 1974 and 1975. Applica­tion of nitrogen increased dry matter and crude protein production in relation to the unfertilized control, but the yield increase was statistically insignificant. Further it was shown that increasing rates of nitrogen had a negative effect on the number and weight of rhizobia. A close negative cor­relation of high significance ( estimated by the t-test) was found between the rates of nitrogen and the number of rhizobia. The experiments conducted …

Some Remarks Concerning The Theory Of Nutrition And Biology Of Grass Stands, A Korab

IGC Proceedings (1977-2023)

The growth rate and yielding capacity of grasses, expressed as kg crude protein/ha per unit of time, are dependent upon the plants' capacity to take up and utilize nitrogen. This character is specific in individual grass species and has been found to be more or less heredi­tarily determined and relatively coincident in different sites. These assumptions and inter­relations have been utilized for determining the yield indices to express not only the rela­tive yielding capacity of major cultivated grasses but also their requirements in terms of effective nitrogen nutrition. The principle of determining effective doses of nitrogen using the index method …

The Intensification Of Grass Production Through Nitrogen Fertilization, And The Nitrate Problem, Klau Ebert, Henrich Koriath, Gunter Rinno

IGC Proceedings (1977-2023)

Two-year pot and five-year field tests with increasing nitrogen doses revealed an increase in the nitrate content of forage grasses. In the pot tests the content of 0.25 % N03-N in the dry matter, which is safe in animal nutrition, had by far been exceeded. In the field tests the· nitrate content increased more slowly for the average of the tests and did not reach this limit when giving 140 to 240 kg N/ha. In single cases this value had, however, already been reached when giving 100 kg N/ha. By selecting grass species with a lesser tendency to nitrate accumulation, …

Yield And Nutritive Value Of Forage Plants As Influenced By Stage Of Plant Development At Harvest, Khindrek Older, Ants Linnutaya, Yulo Oll

IGC Proceedings (1977-2023)

Field experiments were conducted for the pur­pose of studying yield formation in six single­crop sown grass species and two clover/grass mixtures, as well as the. chemical composition and in vitro digestibility of the forage as in­fluenced by the stage of plant development at the time of harvest. Highest dry matter yields were obtained from two-cut use with harvesting in flower. Highest digestible dry matter levels were obtained from three-cut use in the stage of shooting. Highest protein levels were recorded in the context of four-cut use in the heading stage. Digestible nutrients were high in the tillering and shoot­ing stages. …

Forage-Animal Systems For Economic Calf Production, R E. Blaser, R C. Hammes Jr, J P. Fontenot, H T. Bryant

IGC Proceedings (1977-2023)

Nine forage-cow-calf systems with constant ,stocking but variable grazing pressures to pro­vide for changing nutritional needs of beef cows, and continuous high calf nutrition with creep grazing gave similar high weaning weights of autumn and winter calves for all-year grazing vs. hay feeding and for 2 stocking rates. The all-fescue systems lowered calf weights. Nine forage-cow-calf systems with constant ,stocking but variable grazing pressures to pro­vide for changing nutritional needs of beef cows, and continuous high calf nutrition with creep grazing gave similar high weaning weights of autumn and winter calves for all-year grazing vs. hay feeding and for 2 …

Forage And Feedstuff Analysis With Infrared Reflectance Spectro/Computer System1, J S. Shenk, K H. Norris, R F. Barnes, G W. Fissel

IGC Proceedings (1977-2023)

An infrared reflectance spectro/computer sys­tem (IRSCS) has been established at The Pennsylvania State University to evaluate the nutritional quality of forage and feedstuffs. Studies with alfalfa forage clearly show that the reflectance spectral curve of the forage is a composite curve consisting of various chemical constituents in the forage such as water, protein and cellulose. Chemical constituents are not measured directly by IRSCS but calibration prediction equations are developed from sam­ples with known chemical constituents and animal response data. After this is completed, forage samples can be analyzed for multiple chemical constituents and animal responses in less than 2 minutes. …

Exercise Training Prior To And During Cancer In Mice Preserves Muscle Mass, Reduces Tumour Weight And Suppresses Molecular Mediators Of Cachexia, Stavroula Tsitkanou, Pieter J. Koopmans, Ana Regina Cabrera, Nathan Serrano, Calvin S. Peterson, Ruqaiza Muhyudin, Zain B. Malik, Micah Goeke, Eleanor R. Schrems, Francielly Morena, Yuan Wen, Tyrone A. Washington, Kevin A. Murach, Nicholas P. Greene

Physiology Faculty Publications

Abstract: We investigated the prophylactic effects of exercise before and during cancer cachexia (CC) using a model designed to mimic endurance and resistance (i.e., concurrent) adaptations. Male and female Balb/c mice were randomly assigned to exercise or control groups whereby exercise groups were subjected to an 8-week voluntary progressive weighted wheel running (PoWeR) programme of habitual loading-mediated physical activity beginning at 8 weeks of age. At 16 weeks of age, mice were injected bilaterally with colon-26 adenocarcinoma (C26) cells or phosphate-buffered saline, and exercise training was maintained throughout disease progression. Twenty-five days post-tumour induction, we assessed whole-body and muscle phenotype, …

The Evaluation Of Relationships Between Ecological Factors And Production On Permanent Grassland, Vladimir Krajovic

IGC Proceedings (1977-2023)

On 42 sites in 10 districts of the Carpathian region of the CSSR, relationships were exam­ined between grassland production and region­al, climatic (precipitation, temperature, solar radiation), and soil conditions (soil type, pH, S, 'r, V, C0., nutrients, and clay fraction). To this, five variants of fertilization were used (0; PK; 120 kg N/ha + PK, 240 kg N/ha + PK; 480 kg N/ha + PK). None of the natural ecofactors is generally characteristic enough for determining an opti­mal production. But the nutrition and the utilization of grass stands are important under each condition. Therefore, a system of differ­entiated grassland management …

Flood Adaptation And Productivity Of Savanna Grasses, E Gonzalez Jimenez, A Escobar

IGC Proceedings (1977-2023)

Savannas subjected to seasonal flooding occupy· vast areas of the Tropics. Above-ground bio­mass values for Venezuelan flooded savannas are high and related to the longer availability of water. C3 plants colonized the waterlogged unit and showed the highest productivity and nutritive value. This natural system permits a prolonged grazing season. These first results show the great potential for animal production of this ecosystem, stressing the need for coor­dinated research efforts in order to gain a better understanding of it.

Influence Of Plant Nutrition And Method Of Utilization On The Accumulation And Decomposition Of Root Matter In Meadow Soils, Yan Liyv, Rikhard Toomre

IGC Proceedings (1977-2023)

Root matter formation of forage plants de­pends primarily on soil fertility. In fertile soils and under intensive fertilization less root matter is formed than in soils of low fertility. The decomposition of root matter as influenced by microbiological processes was found to be more intensive under grazing than under mow­ing. The application of high rates of nitrogen fertilizer (more than 200 kg N/ha) over longer periods is likely to cause undesirable changes in the relationship between forage plants and soil microorganisms, this resulting in yield decline and in lower efficiency of the fertilizers applied.

New Problems And Results Of Grass Breeding In The Czechoslovak Socialist Republic, Frantisek Bures

IGC Proceedings (1977-2023)

Turf grass species are among the topics of forage grass breeding in Czechoslovakia at present. Breeding goals, however, are highly differentiat­ed, and testing methods have to be adjusted to that diversity of purposes. Agrostis tenuis Sibth., 'Golf variety, is a perennial turf grass which forms short stolons. Tiller formation has been 263/dm2 on average over several years. Its colour is deep green, and the grass is unpretentious in terms of nutrition and soil. Mean root expansibility is 6.9 per cent, mean tensile strength 3,249 kg/cm2, and aver­age compressive strength 112,768 gcm/cm3. Frequent deep mowing is well tolerated. Variety 'K 7' …

The Environment And Population Differences In Anjan Grass (Cenchrus Ciliaris) In Western India, S C. Pandeya

IGC Proceedings (1977-2023)

Cenchrus ciliaris (anjan or buffel grass) is a gregarious fodder species with high nutritive value. The species is an inhabitant of drier sandy areas throughout Africa, Canary Island, Madagascar and eastwards to India, where it mostly occurs in western parts of the country, constituting the States of Gujarat, Rajasthan, Hayana and the adjoining portions of Punjab, U ttar Pradesh and Madhya Pradesh ( called here in as Western India). In Western India, Cen­chrus ciliaris (Cc) variously dominates the nat­urally occurring grazing lands exhibiting great morphological variations with respect to habit. and spike characters. The ecoclimate of Western India is arid …

Inflammation Associated With Obesity, Aging, And Amyloid Burden In Adults With Down Syndrome, Victoria L. Fleming-Batayneh, Brian C. Helsel, Lauren T. Ptomey, Benjamin L. Handen, Mark Mapstone, Melissa Petersen, Sharon J. Krinsky-Mchale, Christy L. Hom, Davneet Minhas, Weiquan Luo, Charles Laymon, Joseph H. Lee, Annie Cohen, Beau M. Ances, Adam M. Brickman, Margaret Pulsifer, H. Diana Rosas, Florencia Lai, Shahid H. Zaman, Elizabeth Head, Dana Tudorascu, Julie Price, Fredrick Schmitt, Bradley T. Christian, Ozioma Okonkwo, Sigan L. Hartley, Beau M. Ances, Howard F. Andrews, Karen Bell, Rasmus M. Birn, Adam M. Brickman

Neurology Faculty Publications

Objective: Adults with Down syndrome (DS) often show elevated systemic inflammation, but the association with obesity, aging, and Alzheimer's disease (AD) pathology is not well understood. Methods: Data were drawn from 188 nondemented adults with DS participating in the Alzheimer Biomarkers Consortium-DS (ABC-DS). Participants completed clinical assessments, blood draws, and neuroimaging. Plasma biomarkers included indicators of general, pro-, and anti-inflammation. Mixed linear models tested associations between BMI, age, PET-measured amyloid burden, and inflammatory biomarkers, adjusting for sex, trisomy type, and collection site. False discovery rate correction was applied. Results: The majority of the participants met criteria for obesity. Higher BMI …

Production Country Origin Impact On Soybean Oil Quality, Huazhen Liu, Micah Pope, Todd Doehring, Pradeep Kachroo, David Hildebrand

Plant and Soil Sciences Faculty Publications

Previous studies have suggested variability in soybean oil quality depending on geographic origin of the soybeans. In this study, 1035 crude degummed soybean oil (raw oil unrefined except for degumming) samples collected from vessels and crushers over five harvest years (2020–2024) were analyzed for 11 key quality attributes. Soybean oil samples were sourced from soybeans that originated from the United States, Brazil, and Argentina. The results indicate that US-grown soybeans consistently produce the highest-quality oil, characterized by the lowest free fatty acid (FFA) levels and lowest neutral oil loss (NOL). Oils from US soybeans also exhibited the highest iodine values. …

Sweet Potato Gene Clusters Control Anthocyanin Biosynthesis And Leaf Morphology, Dong An, Tiechen Shen, Shiyu Wu, Yanshen Li, Weijuan Fan, Mengxiao Yan, Yinghui Meng, Xinyi Wang, Ximing Xu, Zunfu Lv, Ling Yuan, Jun Yang, Guoquan Lu, Hongxia Wang

Plant and Soil Sciences Faculty Publications

Sweet potato (Ipomoea batatas) exhibits diversity in pigmentation and leaf morphology, yet the genetic architecture and regulatory organisation underlying these traits remain poorly resolved, particularly with respect to organ-specific control. We hypothesised that phenotypic variation is governed by clustered genetic modules comprising regulatory and structural genes operating in an organ-specific manner. To test this, we conducted genome-wide association studies (GWAS) using 4.6 million SNPs across 260 diverse accessions, integrated with transcriptomic, haplotype and functional analyses. GWAS identified two tandem clusters of MYB transcription factors on chromosome 5 as the primary regulators of leaf anthocyanin accumulation. Expression profiling, heterologous expression and …

Permanent Winter Hay-Feeding Stations Concentrate Soil Nutrients In Kentucky Pastures, Alan J. Franzluebbers, Jeffrey W. Lehmkuhler, Matt H. Poore, Arjun Kafle, Rodolfo Zentella, Tommy Yankey, S. Ray Smith, Gregory Halich

Animal and Food Sciences Faculty Publications

Distribution of soil nutrients as a function of centralized winter hay-feeding stations can lead to inefficient nutrient utilization and environmental quality concerns, but distributions have not been adequately characterized across a diversity of soils. We investigated spatial distribution of soil nutrients and organic matter fractions on three farms with concrete feeding pads for winter hay feeding. Soils were silt loam at the Princeton and Oran Little Research Stations and silty clay loam and silty clay at the Eden Shale Farm in ≥20-year-old tall fescue (Lolium arundinaceum) pastures in Kentucky. An anticipated impact zone of 0.7–1.0 ha around the winter hay-feeding …

Three Centuries Of Technological Innovation, Jordan G. Okie, James H. Brown, Astrid Kodric-Brown, Joseph R. Burger, Tatiana P. Flanagan, Trevor S. Fristoe, Sean T. Hammond, Norman Mercado-Silva, Jeffrey C. Nekola, Jennifer Richter

Biology Faculty Publications

What socioecological conditions nurture the ingenuity and collaborative interactions underlying transformative technological innovations? We compiled a dataset on more than 400 major technological inventions from 1690 to 1990 spanning seven categories (agriculture, armaments, information and communication, household, industry, medical, and transportation) and performed inductive macroecological analyses to address how attributes of inventors, teams, and their social and geographic environments contributed to the innovation of new technologies that have changed the way people live. The vast majority of inventions were attributed to single inventors of various ages. The frequency, size, and cultural diversity of teams increased in the 20th Century, as …

Optimizing The Use Of Grazed Dryland Pasture In Western Oregon, T E. Bedell

IGC Proceedings (1977-2023)

When they are properly fertilized, western Oregon dryland pastures of subterranean dover with grasses such as perennial rp:g:rass, tall fescue, and resident annuals produce total annual dry-matter yields averaging 6,500 kg/ha. Some sites are capable of over 9,000 kg/ha. Optimum use of this forage is complicated by its highly seasonal availability. Over 50 % of the total growth occurs from late April to mid-June. Only about 10% takes place during autumn-early winter, and virtually none occurs during summer. Research shows livestock weight gains from 300 to over 700 kg/ha can be expected depending upon pasture mixture and kind of grazing …

Diet Quality Considerations In The Design And Management Of Pastures In Seasonally Dry Tropics Of Australia, R L. Mccown, C J. Gardener

IGC Proceedings (1977-2023)

Much of Australian tropical-pasture research in the last 20 years has been aimed at filling the "protein gap" of the dry season with a well-adapted legume. Several such legumes are now available, but their contribution to an improved nutritional regimen has been variable. This paper puts forward generalizations as to the contribution of pasture components to cattle nutrition and attempts to apply this information in devising regional strategies for pasture design and management. The contribution of a forage component is a function of (1) its nutritive value and (2) its relative acceptability. Three components emerge as both highly nutritious and …

Development Of A Pasture Research Program For The Tropical Savanna Region Of Brazil, D Thomas, C P. Moore, W Couto, R P. De Andrade, C.M C. Da Rocha, D T. Gomes

IGC Proceedings (1977-2023)

The tropical savannas (cerrados) of west central Brazil contain almost 40% of the nation's cattle population. However, the low productivity and nutritive value of the native pastures is a serious limitation to cattle production. To improve the nutrition of the grazing animal, a research program has been developed with emphasis on the integrated use of cultivated pastures. The program aims (1) to select species adapted to the cerrados, (2) to determine their nutrient requirements, and (3) to develop methods of establishment and utilization. The program is being conducted at the Cerrados Agricultural Research Center (CP AC) at lat 15°S. Rainfall …

Yield And Quality Of Tropical Legumes During The Dry Season: Galactia Striata (Jacq.) Urb., R R. Vera, E A. Pizarro, M Martins, J.A. C. Viana

IGC Proceedings (1977-2023)

A small-plot experiment was conducted during 2 consecutive years in the cerrados of Brazil to evaluate the effect of four dates of deferment (21 February, 7 and 21 March, and 4 April, respectively) on rate of growth, chemical composition, and in-vitro dry-matter digestibility (IVDMD) of a pure stand of Galactia striata, a naturalized legume. The chosen dates of deferment em­braced the last 2 months of the rainy season. Yields were estimated at intervals of 28 days, over an experimental period of 237 days, ending with the beginning of the following rainy season. Asymptotic growth was observed throughout the experimental period. …