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University of Kentucky

Theses/Dissertations

2017

Dentistry

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Use Of Clonidine In Sedation Dentistry, Asma Kumar Jan 2017

Use Of Clonidine In Sedation Dentistry, Asma Kumar

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Background:

Clonidine is an alpha-2 adrenergic agonist which has been used to treat hypertension for over 40 years. In October 2008, clonidine was approved by the FDA for use as a premedication agent prior to sedation. The overall goal of this study is to determine if clonidine can be used as a pre- operative sedative agent in moderate sedation dentistry and if so, what should be considered a safe level.

The following specific aims were established for this study:

  1. To determine whether patients receiving clonidine required less intravenous medications.
  2. To determine if clonidine can lower blood pressure and pulse to …