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University of Connecticut

Theses/Dissertations

2017

Alginate

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Alginate Hydrogels For Bone Tissue Regeneration, Stephanie T. Bendtsen Apr 2017

Alginate Hydrogels For Bone Tissue Regeneration, Stephanie T. Bendtsen

Doctoral Dissertations

Bone tissue engineering is employed to help enhance regeneration of bone tissue that may have difficulty of achieving sufficient healing on its own. As bones tend to break in irregular manners, methods to produce engineered scaffolds more closely fitting the geometry of the defective tissue are desirable. Current techniques to produce engineered bone tissue constructs result in stiff, rigid scaffolds with limited plasticity and ability to form irregular architectures. Additionally, processing methods limit the feasibility to uniformly incorporate live cells into the scaffolds for enhanced uniform healing. The use of hydrogel materials for bone tissue engineering has gained interest due …