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Alginate Hydrogels For Bone Tissue Regeneration, Stephanie T. Bendtsen Apr 2017

Alginate Hydrogels For Bone Tissue Regeneration, Stephanie T. Bendtsen

Doctoral Dissertations

Bone tissue engineering is employed to help enhance regeneration of bone tissue that may have difficulty of achieving sufficient healing on its own. As bones tend to break in irregular manners, methods to produce engineered scaffolds more closely fitting the geometry of the defective tissue are desirable. Current techniques to produce engineered bone tissue constructs result in stiff, rigid scaffolds with limited plasticity and ability to form irregular architectures. Additionally, processing methods limit the feasibility to uniformly incorporate live cells into the scaffolds for enhanced uniform healing. The use of hydrogel materials for bone tissue engineering has gained interest due …


From The Science Of Nanorod Growth To Low Temperature Metallic Attachment, Paul R. Elliott Feb 2017

From The Science Of Nanorod Growth To Low Temperature Metallic Attachment, Paul R. Elliott

Doctoral Dissertations

To move nanotechnology out of the lab and into common use requires understanding and experience of the structures and processes involved. The technological maturity allowing the widespread use of nanotechnology is practically nonexistent outside of the integrated circuit industry. This work provides a synergy of the science of nanorod growth and the technology of metallic glue in ambient. Starting from the science, this thesis presents the design and control of the structure and morphology of nanorods grown by physical vapor deposition. We demonstrate the use of deposited seeds as a method to control the diameter and spacing of surface grown …


Part I Convergent Total Synthesis Of Bioactive Dipeptide–Lipids Isolated From Porphyromonas Gingivalis: Possible Biomarker For Multiple Sclerosis Part Ii Synthesis Of Nitroimidazole Indocyanine Green Dye Conjugates For Targeting Hypoxia In Tumor Cells For Near Infrared Fluorescence Frequency Domain Optical Tomography, Christopher James Dietz Jan 2017

Part I Convergent Total Synthesis Of Bioactive Dipeptide–Lipids Isolated From Porphyromonas Gingivalis: Possible Biomarker For Multiple Sclerosis Part Ii Synthesis Of Nitroimidazole Indocyanine Green Dye Conjugates For Targeting Hypoxia In Tumor Cells For Near Infrared Fluorescence Frequency Domain Optical Tomography, Christopher James Dietz

Doctoral Dissertations

Mankind’s greatest attribute is the capability of higher order intellect being applied to prolonging life and improving one’s overall health. Modern medicine and the research therein has created opportunities to understand and combat disease at incredible levels. Yet, some of the most befuddling diseases are ones that our own bodies inheritably produce. Autoimmune disease is a condition in which the body’s own defense mechanisms begin to target healthy cells as if they were foreign threats. Cancer is a condition in which abnormal cell growth can spread throughout the body and begin to shut down vital bodily functions. Medicinal chemistry has …