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Keynote Address And Meeting Program, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

Hydration Strategies In Ultra-Endurance Running: A Narrative Review Of Programmed Versus Thirst-Driven Approaches, Shawn C. Wierick, Rosie I. Perez, Xiujing Zhao, Brendon P. Mcdermott

Health, Human Performance and Recreation Faculty Publications and Presentations

Background/Objectives: Ultra-endurance running (UER) presents unique hydration challenges due to prolonged duration, variable terrain, environmental extremes, and gastrointestinal limitations. Athletes often use either programmed fluid intake (PFI), which prescribes fluid volumes based on estimated sweat rate, or thirst-driven fluid intake (TDFI), which relies on internal cues. This review examines the effectiveness and limitations of each strategy in the context of UER performance and safety. Methods: A narrative review was conducted using a targeted selection of peer-reviewed studies. Both laboratory- and field-based research were included to evaluate the physiological rationale, practical feasibility, and outcomes associated with PFI and TDFI. A total …

Effects Of Flavonoids On Reducing Colon Cancer Risk Via Macrophage Polarization, Gracien Jules

Graduate Theses and Dissertations

Colorectal cancer is one of the most fatal diseases in the United States. Chronic tissue inflammation can cause cell proliferation, which leads to tumor formation and cancer development. Macrophages are responsible for maintaining tissue homeostasis and for inflammatory responses. M1 macrophages exhibit proinflammatory responses while M2 macrophages exhibit anti-inflammatory responses. Imbalance between M1 and M2 macrophages is closely related to inflammation-associated disease development. The anti-inflammatory effects of apiaceous vegetable constituents, specifically flavonoids, have been studied for their preventative effects towards reducing disease risk. However, sufficient evidence is lacking on the mechanisms by which flavonoids impact M1/M2 macrophage polarization. RAW 264.7 …

Student Perceptions And Academic Performance When Taught With Multiple Active Learning Methods In A High Enrollment Undergraduate Human Physiology Course, Kate Ireton Walker

Graduate Theses and Dissertations

When instructing very large groups of students in science, it can be difficult to engage all students in the content and measure their understanding. A major unaddressed challenge in science instruction is how specifically to design and implement strategies that engender active learning particularly in high-enrollment undergraduate courses. Active learning, which represents a diverse set of strategies, may include student engagement as part of instruction through discussions, active movement, and application (Bernstein, 2018; Cavanagh, et al. 2016; Michael, 2006 & Wilke, 2003). This study was designed to provide data addressing the gap in the literature regarding how the continual implementation …

Real-Time Measurements From Wearable Sensors To Enhance Stability On Uneven Terrain, Sophie Copelin

Biomedical Engineering Undergraduate Honors Theses

The presented thesis is a study of sensation associated with inversion/eversion movement about the anterior/posterior axis. The long-term goal is to create a system that provides feedback to a prosthesis user, so their chances of falling is decreased. This feedback system would use wearable sensors to detect certain angles, so that sensory feedback could be provided. The study aimed to determine if Xsens Movella DOT sensors could be used in a system like this, so the accuracy of the Xsens Movella DOT sensors was assessed and the difference in angles that could be determined by them when compared to that …

Exploring The Effects Of N,N-Dimethylbiguanide And Ω-3 Pufas On Muscle Stem Cell Differentiation, Enayah Alhshim

Graduate Theses and Dissertations

The impacts of omega-3 (ω-3) fatty acid and metformin hydrochloride (Met-HCl) on muscle stem cells differentiation, mimicking the fetal muscle development under gestational diabetes mellitus (GDM), were investigated. ω-3 fatty acids have been known for their ability to regulate adipogenic transcription factors such as Sterol Regulatory Element-Binding Protien (SREBPs) and Peroxisome Proliferator-Activated Receptors (PPARs). This regulation resulted in gene expression modification for lipid metabolism and adipocyte differentiation, thus preventing excessive fat accumulation. Additionally, emerging evidence suggested that ω-3 fatty acids may also exert direct effects on myogenic processes that influence muscle stem cells proliferation, differentiation, and maturation. Meanwhile, Met-HCl, an …

Lack Of Access To Healthcare And Neurology Within East Texas, Ashton Arlen

Health, Human Performance and Recreation Undergraduate Honors Theses

Within East Texas, there is a critical shortage of physicians and lack of access to healthcare that is taking a major toll on the health of residents. For Texas as a whole, almost 70% of their 254 counties are classified as a rural. Within the United States, Texas has the largest amount of hospital closures and rural areas including East Texas have lost over half of their hospitals since 1960 (Nevins et al. 2021). The area endures some of the highest rates of chronic health conditions such as obesity, diabetes, cancer, and mental health conditions.

In knowing about the many …

In Vivo Measurement Of Nadh Fluorescence Lifetime In Skeletal Muscle Via Fiber-Coupled Time-Correlated Single Photon Counting, Kathryn M. Priest, Jacob V. Schluns, Nathania Nischal, Colton L. Gattis, Jeffery C. Wolchok, Timothy J. Muldoon

Biomedical Engineering Faculty Publications and Presentations

Nicotinamide adenine dinucleotide (NADH) is a cofactor that serves to shuttle electrons during metabolic processes such as glycolysis, the tricarboxylic acid cycle, and oxidative phosphorylation (OXPHOS). NADH is autofluorescent, and its fluorescence lifetime can be used to infer metabolic dynamics in living cells. Fiber-coupled time-correlated single photon counting (TCSPC) equipped with an implantable needle probe can be used to measure NADH lifetime in vivo, enabling investigation of changing metabolic demand during muscle contraction or tissue regeneration. This study illustrates a proof of concept for point-based, minimally-invasive NADH fluorescence lifetime measurement in vivo. Volumetric muscle loss (VML) injuries were …

The Impact Of Low Appendicular Skeletal Muscle Mass In The Development Of Insulin Resistance And Metabolic Syndrome: A Systematic Review Of The Literature, Ella Boston

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Chronic conditions are the leading cause of death and disability. More specifically, cardio-metabolic disease is the number one cause of death worldwide. The tragedy and burden of disease is unrefuted; even more so, evidence indicates that realistic modifications of lifestyle can prevent most chronic disease. Metabolic syndrome and insulin resistance are leading risk factors in the development of cardio-metabolic disease. Presently, chronic disease is treated through symptomatic evaluation of risk. Reframing the lens of care through root cause evaluation is fundamental to optimizing patient outcomes. The purpose of this systematic review is to synthesize literature evaluating the impact of low …

Fatty Females And Muscular Males: Investigating Human Sexual Dimorphism Across The Upper And Lower Skeleton, Brooklin Edwards

Anthropology Undergraduate Honors Theses

The sexual dimorphism profile of human body composition produces a unique pattern. Compared to other primates, humans have a mild size dimorphism; however, human males have a particularly muscular upper body and human females have a permanent fatty composition. These findings have resulted in varying interpretations related to sexual selection, mating systems, and male competition. Using humerus and femur measurements collected from 9 primate species, we investigated how the pronounced sexually dimorphic tissue composition of humans influences skeletal elements compared to the other primates. We hypothesized that over the course of human evolution, human females developed a body composition that …

You Eat How You Think: A Review On The Impact Of Cognitive Styles On Food Perception And Behavior, Thadeus L. Beekman, Philip Glen Crandall, Han-Seok Seo

Food Science Faculty Publications and Presentations

Sensory perception is understood to be a complex area of research that requires investigations from a variety of different perspectives. Although researchers have tried to better understand consumers' perception of food, one area that has been minimally explored is how psychological cognitive theories can help them explain consumer perceptions, behaviors, and decisions in food-related experiences. The concept of cognitive styles has existed for nearly a century, with the majority of cognitive style theories existing along a continuum with two bookends. Some of the more common theories such as individualist-collectivist, left-brain-right-brain, and convergent-divergent theories each offered their own unique insight into …

Effects Of Cognitive Style On Food Perception And Eating Behavior, Thadeus Lyndon Beekman

Graduate Theses and Dissertations

Within the fields of psychology, notably cultural psychology, the analytic-holistic cognitive style theory has been introduced, developed, fine-tuned, and validated across a wide range of situations, stimuli, and populations. This research, combined with recent applications of the analytic-holistic theory, suggests that the differences in analytic or holistic tendencies of individuals in food, sensory, and consumer tests can impact food perception and associated behaviors. This dissertation aimed to investigate the impact of analytic-holistic cognitive styles of consumers in food situations. The first objective to accomplish this goal was to conduct exploratory research to identify if and where the analytic-holistic theory may …

Hyper Stable Variants Of Fgf-1-Fgf-2 Dimer, Madison Shields Mcclanahan

Chemistry & Biochemistry Undergraduate Honors Theses

Fibroblast Growth Factors (FGFs), including FGF-1 and FGF-2, are proteins that play a crucial role in cell proliferation, cell differentiation, cell migration, and tissue repair. FGF-1 and FGF-2 are useful in accelerating the healing process in the human body; however, these proteins are naturally thermally unstable, resulting in a relatively low half-life in vivo. 1,8 In efforts to improve the stability of this protein, FGF-1 and FGF-2 proteins are engineered by combining the amino acid sequences of the two proteins to form a heterodimer and obtain novel properties. These two FGF variants are chosen for their specific wound healing capabilities. …

Visualizing Interdisciplinary Collaborations Within Exercise Science: A Pilot Study, Elizabeth Bjornsen

Graduate Theses and Dissertations

Exercise science is a growing field with sub-disciplines exploring various aspects of physical activity. Diverse perspectives allow the field to answer complex research questions, but little is known about the collaborative nature of exercise science today. Research practices have implications on undergraduate curriculum, likely incorporating experiential knowledge into course subject matter and providing diverse experiences for students entering the workforce. Therefore, the purpose of the pilot study is to visualize and quantify interdisciplinary collaborations within exercise science. Journal citation analysis and an adaptation of social networking theory were utilized to examine collaborative practices of exercise science faculty at the University …

Breakfast Boost Study: Defining The Role Of Breakfast Macronutrient Composition On Markers Of Childhood Obesity, Caroline Ganoung

Human Nutrition and Hospitality Management Undergraduate Honors Theses

Abstract

Background: Childhood obesity is a serious problem in the United States, affecting ~19% of children 2-19 years of age. Breakfast is a key component of a healthy diet and can positively impact children’s health. However, there has been a steady decline in breakfast consumption in children over the past 40 years.

Methods: The objective of this study was to determine if breakfast macronutrient composition, protein (PRO)-based breakfast (30 g protein, 31 g carbohydrate, 11.7 g fat) or an isocaloric (360 kcal) carbohydrate (CHO)-based breakfast (13 g protein, 48 g carbohydrate, 11.7 g fat), can influence postprandial appetite and food …

Characterization Of Avidin And Case9 Single Protein Molecules By A Solid-State Nanopore Device, Haopeng Li

Graduate Theses and Dissertations

The shape and charge of a protein play significant roles in protein dynamics in the biological system of humans and animals. Characterizing and quantifying the shape and charge of a protein at the single-molecule level remains a challenge. Solid-state nanopores made of silicon nitride (SiNx) have emerged as novel platforms for biosensing such as diagnostics for single-molecule detection and DNA sequencing. SSN detection is based on measuring the variations in ionic conductance as charged biomolecules translocate through nanometer-sized channels driven by an external voltage applied across the membrane. In this paper, we observe the translocation of asymmetric cylindrical structure CRISPR-Cas9 …

Nutritional Supplementation And Skeletal Muscle Health In Chronic Diseases, Hexirui Wu

Graduate Theses and Dissertations

Prevalence of chronic diseases in the United States keeps increasing in recent years. There are approximately four in ten adults having chronic diseases in America. Chronic diseases include obesity, aging, heart diseases, cancer and many others. This thesis mainly focuses on obesity and aging. Skeletal muscle performance is impaired in obesity and aging conditions. One common reason causing this could be higher fat mass and lower muscle mass. However, there is no study showing what pathways are involved in the imbalance of body composition. Therefore, the first objective of the thesis is to determine gene expression of selected pathways in …

Gender In Apocalyptic California: The Ecological Frontier, Marykate Eileen Messimer

Graduate Theses and Dissertations

Climate change is the consequence of ideologies that promote human reproduction and resource consumption by sacrificing human justice, nonhuman species, and the land. Both biology and queer ecologies resist this notion of human separation and supremacy by showing that no body is a singular, impermeable entity, that all beings are biologically and inexorably connected. My dissertation demonstrates that fiction writers use this knowledge to locate a utopian vision that can counteract the dystopian impotence of living within climate change. This argument is founded on novels written by women and set in California, a state that uniquely inhabits a utopian and …

Characterization Of The Swine Gut Microbiome Dynamics, Culturomics And Probiotics, Xiaofan Wang

Graduate Theses and Dissertations

The gastrointestinal tract is a critical place where the immune system concentrates many of its protective functions. It exerts both physical and biochemical defenses against invading foodborne pathogens and other hazards. In pigs, the gut microbiota community assembled postnatal plays a very important role in the development of multiple physiologic aspects, such as development of the gastrointestinal tract, nutrient exchange, immune defense against foreign pathogens and growth performance. Microbiome-host communication changes with age. Despite recent advances in understanding the swine gut microbiome at different growth stages, a comprehensive longitudinal study of the lifelong dynamics of the swine gut microbiome is …

Role Of Angiotensin I And Ii On The Tissue Mechanics Of The Aortic Heart Valve Via Receptor Binding And Converting Enzymes, Josh Fahy

Biomedical Engineering Undergraduate Honors Theses

The renin-angiotensin system (RAS) plays a crucial role in the regulation of renal, cardiac, and vascular physiology. This system regulates in vivo blood pressure and fluid balance. As renal blood flow decreases, the kidneys convert prorenin into renin and secrete it into the circulatory system. Renin then converts angiotensinogen into angiotensin I (ang-I). The ang-I is then converted into angiotensin II (ang-II) by the angiotensin-converting enzyme (ACE). Ang-II, a vasoconstrictor, increases blood pressure by causing the blood vessels to narrow. Recent evidence suggests that RAS may be involved in the progression of valve disease, most notably, aortic stenosis.

The first …

A Comparison Of The Curricula Of The Top-Ranked Prelicensure Baccalaureate Nursing Programs In The United States, Silvia Imanda

Graduate Theses and Dissertations

What constitutes an ideal prelicensure nursing curriculum is not well understood. Specifically, what are the strategic curricular sequencing and curricular themes or focus might be included to contribute to producing high quality graduates? The purpose of this qualitative multiple case study investigation was to look at successful programs and identify effective curricular sequencing and curricular themes or focus that might be inferred to have contributed to producing high quality graduates. Seven top-ranked prelicensure baccalaureate nursing programs were selected based on three national college rankings services. Based on data from interviews and publicly accessible documents, seven case studies were compared and …

Development Of A Methodology For Predicting Consumer Acceptance And Preference Toward Beverages, Shilpa Shailesh Samant

Graduate Theses and Dissertations

Consumer behavior toward food/beverages is influenced by multisensory attribute perceptions as well as emotional experiences. Traditional methods of sensory testing lack the ability to capture emotional responses and as a result, measuring food/beverage-evoked emotions remains a research challenge. There were three objectives of this dissertation study. Firstly, this study aimed to develop prediction models of acceptance of and preference for basic taste solutions using sensory attribute intensities and emotional responses. Secondly, this study aimed to extend the findings of the first objective to develop prediction models of commercially-available vegetable juice products in terms of (a) acceptance and preference under blind-tasting …

Graduate Athletic Training Education Program Newsletter, Fall 2018, University Of Arkansas, Fayetteville. Athletic Training Education Program

Athletic Training Education Newsletter

No abstract provided.

Effects Of Serving Temperature On Sensory Perception And Acceptance Of Brewed Coffee, Matthew James Chapko

Graduate Theses and Dissertations

Coffee continues to be one of the most widely consumed beverages worldwide. How an individual perceives a cup of coffee is impacted by a plethora of factors including origin, growing climate, roasting level, and consumption habits. This thesis utilized both trained descriptive panelists and untrained consumer panelists to analyze how serving/consumption temperature modulates sensory perception of brewed coffee in regards to appearance, aroma, flavor, taste, and mouthfeel. Three varieties of coffee (Colombia, Ethiopia, and Kenya) were brewed and served to panelists at four temperatures: 70, 55, 40, and 25 °C. In one study (Study 1, Chapter 3), results from descriptive …

Annual Report Of The Wally Cordes Teaching And Faculty Support Center For The Year Ended…, 2018, University Of Arkansas, Fayetteville. Wally Cordes Teaching And Faculty Support Center

Wally Cordes Teaching and Faculty Support Center Annual Report

No abstract provided.

Determination Of The Effects Of Different Maillard Reaction Products On The Taxonomic Composition Of The Gut Microbiota, Nesreen Hamdan Aljahdali

Graduate Theses and Dissertations

The Maillard Reaction (MR) is a non-enzymatic chemical reaction which results in linkage between the amino group of amino acids and the carbonyl group of reduced sugars. This reaction generates Maillard reaction products (MRPs) which are not present naturally in foods, and are responsible for a range of colors, odors, flavors, and other sensory properties. Conflicting reports of MRPs impacts on human health are probably due to the fact that bioconversion of these digestible molecules by the gut microbiota has been marginally taken into account. This study aimed to determine the effects of different MRPs on rodent’s gut microbiota through16S …

Piglet Gut Microbiota Responses To Exposure To Outdoor Simulated Environment And Formula Feeding, Nguyen Vo

Graduate Theses and Dissertations

Several lines of evidence suggest that early-life gut microbiota composition is a crucial determinant of the susceptibility to diseases later in life. Understanding the evolution of early-life gut microbiota and critical factors that can modify this microbial community will espouse the prevention or reversion of health risk originating from dysbiosis of the gut microbiota in the early stage. In this research, we hypothesized that alterations in the environment (simulation of rural conditions by soil exposure) and feeding mode (breastmilk versus formula milk) will have significant impacts on the establishment of the gut microbiota in early life. At first, in literature …

Athletic Training Education Program Newsletter, Fall 2017, University Of Arkansas, Fayetteville. Athletic Training Education Program

Athletic Training Education Newsletter

No abstract provided.

The Effect Of Blinded Hydration State On Thermoregulation And Performance In Male Cyclists, Jon David Adams

Graduate Theses and Dissertations

Purpose: The purpose of these studies was to observe the effect of dehydration on exercise performance while subjects were blinded to their hydration status. Methods: Study 1: Seven male cyclists (weight: 71±8 kg, body fat: 14±6%, VO2peak: 59.4±6 ml∙kg-1·min-1) exercised for 2 hours on a cycle ergometer at 55% VO2peak, in a hot-dry environment (35°C, 30% rh), with a nasogastric (NG) tube under euhydrated (EUH-NT) and hypohydrated (DEH-NT) conditions. In both trials, thirst was matched by drinking 25 mL every 5 min. In the EUH-NT trial sweat losses were fully replaced via the NG tube. Following the 2 hours of …

A Numerical Study Of The Interaction Between One Dimensional Carbyne Chain And Single Stranded Dna, Zeina Salman

Graduate Theses and Dissertations

resolution at the single nucleotide level when developing DNA sequencers. The purpose of this research was to numerically study the electrical properties associated with the interaction between 1D carbon chain, known as carbyne, and ssDNA. First, the electrical properties of the carbyne chain were calculated. Second, the electrical properties of the carbyne chain were calculated in the presence of different ssDNA bases. Analyzing the differences between the two cases led to determining the effects of these different bases on the electrical properties. The numerical simulation approach conducted in this research was based on the first-principle simulation. The first-principle simulation was …