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Myoepithelial Cell Morphogenesis And Differentiation In The Mouse Submandibular Salivary Gland In Development And Disease, Elise Marie Gervais Jan 2015

Myoepithelial Cell Morphogenesis And Differentiation In The Mouse Submandibular Salivary Gland In Development And Disease, Elise Marie Gervais

Legacy Theses & Dissertations (2009 - 2024)

Organogenesis is the process by which tissues organize, gain considerable size, and undergo cellular differentiation or specialization to form fully functional organs. To study the processes involved in organogenesis of branched organs, the mouse submandibular salivary gland is frequently used as a model system, as it can undergo morphogenesis and differentiation and be genetically manipulated ex vivo. The mouse submandibular salivary gland undergoes a specific process of outgrowth and invagination known as branching morphogenesis which allows for the significant increase in gland size and complexity, as well as maximization of surface area for secretion of saliva. Surrounding the mouse submandibular …


Three Essays In Program Evaluation, Jungtaek Lee Jan 2015

Three Essays In Program Evaluation, Jungtaek Lee

Legacy Theses & Dissertations (2009 - 2024)

I evaluate a wider range of public policies with program evaluation methods, difference-in-difference regression method and regression discontinuity design. The first chapter considers the causal relationship between the expansion on dependent coverage of the Affordable Care Act and risky behaviors including smoking and drinking. I also examine the effect of coverage on preventive care and health care utilization. To overcome the endogeneity problem, I exploit a regression discontinuity design to estimate the causal effect of losing health insurance. I find that young adults those who turned 26 are 8 to 10 percent more likely to lose health insurance than young …


Human Feeding Biomechanics : Intraspecific Variation And Evolution, Justin Ledogar Jan 2015

Human Feeding Biomechanics : Intraspecific Variation And Evolution, Justin Ledogar

Legacy Theses & Dissertations (2009 - 2024)

This study examines feeding biomechanics in modern human crania and those of extinct early members of the human lineage in order to better understand the selective pressures that influenced human craniofacial evolution. Specifically, this study uses finite element analysis to examine: 1) human feeding performance, in terms bite force production and craniofacial strength; 2) intraspecific variation in human feeding biomechanics; 3) feeding biomechanics in fossil hominins, including Australopithecus sediba and Homo habilis, species that are potentially at the root of modern human lineage, and 4) the functional role of purported facial buttresses.


We Might Be Mad Here : An Archaeological Investigation Of Institutional Life In The Northeast, Rachel Manning Jan 2015

We Might Be Mad Here : An Archaeological Investigation Of Institutional Life In The Northeast, Rachel Manning

Legacy Theses & Dissertations (2009 - 2024)

The establishment of almshouses in the United States provided a way for states to offer housing to their poor and destitute populations. Throughout the 20th century, most of these establishments changed their function, with many of them morphing into asylums for the mentally insane. Grave assemblages have been collected through archaeological excavations, typically when significant changes are expected to be made to what was once property of the almshouse. This study compares the artifact assemblages of three contemporaneous almshouses: the Oneida and Onondaga County Almshouses of New York State and the Uxbridge Almshouse of Massachusetts. While the associated artifacts are …


Three Essays On Risks In The Middle-Aged And Elderly In Japan, Daisuke Moriwaki Jan 2015

Three Essays On Risks In The Middle-Aged And Elderly In Japan, Daisuke Moriwaki

Legacy Theses & Dissertations (2009 - 2024)

This dissertation consists of three essays on the risks facing the middle-aged and elderly in Japan.


Examining The Craniofacial Biomechanics Of Paranthropus Boisei, Amanda L. Smith Jan 2015

Examining The Craniofacial Biomechanics Of Paranthropus Boisei, Amanda L. Smith

Legacy Theses & Dissertations (2009 - 2024)

An engineering method, finite element analysis (FEA), was used to examine the craniofacial biomechanics of Paranthropus boisei. The craniofacial morphology of Paranthropus boisei exhibits a number of highly derived characteristics that have commonly been thought to be related to feeding. This series of studies includes an ex vivo strain gage study (validation of techniques), an assessment of the effects of intraspecific craniofacial shape variation in chimpanzees (Pan troglodytes), and an examination of the feeding biomechanics of Paranthropus boisei. Modeling experiments were also conducted to test mechanical hypotheses regarding the effects of specific derived craniofacial features on Paranthropus feeding function.


An Investigation Of Alkaline Earth And Rare Earth Elements In Human Bone Following Long-Term Parenteral Nutrition, Aubrey L. Galusha Jan 2015

An Investigation Of Alkaline Earth And Rare Earth Elements In Human Bone Following Long-Term Parenteral Nutrition, Aubrey L. Galusha

Legacy Theses & Dissertations (2009 - 2024)

This investigation focused on a unique collection of archived human bones obtained post-mortem from 7 patients, who had received long-term parenteral nutrition (PN) for up to 21 years. Parenterals are administered intravenously as a nutritional supplement, and may be contaminated with metals, which are completely absorbed into the blood compartment. Some metal contaminants may be deposited in the body’s reservoir for inorganic elements – bone.