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Effects Of Carbachol And Vitamin C On Submandibular Salivary Gland Branching Morphogenesis, Nasiratu Larry
Effects Of Carbachol And Vitamin C On Submandibular Salivary Gland Branching Morphogenesis, Nasiratu Larry
Biological Sciences
The Submandibular Salivary Gland (SMG) is formed by iterative branching of epithelial cells into secretory acinar endbuds and branched ducts that are extensively innervated by parasympathetic nerves which can influence gland development. Carbarrylcholine or carbachol, (an acetylcholine neurotransmitter analog), is a drug that binds to and activates the acetylcholine receptor. Previous research has suggested that carbachol on SMGs might delay ductal differentiation and affect actin localization in cells lining the lumen of ducts. Vitamin C has been shown to enhance matrix protein synthesis, which may accelerate cell differentiation. My goal was to test whether and how carbachol or modulation of …
Biomonitoring For Exposure To Trace Elements In Utero : Analysis Of The Human Placenta, Pamela Catherine Kruger
Biomonitoring For Exposure To Trace Elements In Utero : Analysis Of The Human Placenta, Pamela Catherine Kruger
Legacy Theses & Dissertations (2009 - 2024)
The placenta forms in eutherian mammals, and is responsible for the nutrition of the developing fetus. However, maternal exposure to environmental pollutants both before and during pregnancy may result in the passage of toxins through the placental barrier and into fetal tissues. The placenta is the only organ derived from both maternal and fetal tissues, and establishes a link between the fetus and the environmental exposures of the mother. The analysis of placentae for the presence of environmental pollutants offers the possibility of exposure measurements in both the mother and the developing fetus. Specifically, trace element determination in human placentae …