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A New Theory Of Stochastic Integration, Anuwat Sae-Tang Jan 2011

A New Theory Of Stochastic Integration, Anuwat Sae-Tang

LSU Doctoral Dissertations

In this dissertation, we focus mainly on the further study of the new stochastic integral introduced by Ayed and Kuo in 2008. Several properties of this new stochastic integral are obtained. We first introduce the concept of near-martingale for non-adapted stochastic processes. This concept is a generalization of the martingale property for adapted stochastic processes in the It\^o theory. We prove a special case of It\^o isometry for the stochastic integral of certain instantly independent processes. We obtain some formulas for expressing a new stochastic integral in terms of It\^o integrals and Riemann integrals. Several generalized versions of It\^o's formula …


Plasma Nitrite Reserve And Vascular Function Before And After Handgrip Training In Patients With Heart Failure, Daniel Paul Credeur Jan 2011

Plasma Nitrite Reserve And Vascular Function Before And After Handgrip Training In Patients With Heart Failure, Daniel Paul Credeur

LSU Doctoral Dissertations

There is a direct relationship between vascular health and physical function. The controllers of this relationship are unclear, but appear to involve biomechanical and biochemical influences on the vascular wall. Purpose: The purpose of this dissertation was twofold: (1) to explore the relationship between vascular health and physical function in three populations (elderly, young and chronic heart failure patients); and (2) to determine the modifying role of physical activity, inactivity and exercise training on controllers of this relationship. Methods: Four projects were designed to address 3 key issues in exercise vascular biology, including the influence of the pattern of blood …


Understanding The Selective Detection Of Homocysteine And Studies Toward The Synthesis Of Vinigrol, Dong Wang Jan 2011

Understanding The Selective Detection Of Homocysteine And Studies Toward The Synthesis Of Vinigrol, Dong Wang

LSU Doctoral Dissertations

The first part of the work is dedicated to the selective detection of Homocysteine (Hcy). In order to better understand this colorimetric detection method, a thermodynamic model for the pH dependence of the effective reduction potential of Hcy derived á-carbon radicals has been proposed. And using viologen indicators of varying reduction potentials, we demonstrate that colorimetric changes occur at experimental pH values consistent with the model. The one-carbon bridge stereochemistry of bicyclo[3.3.1]nonane framework is critical to make the third ring of the tricyclic precursor of vinigrol. We studied this stereochemistry carefully and found that the major diastereomer formed from Robinson …


Fully Integrated Microsystem For Bacterial Genotyping, Hui-Wen Chen Jan 2011

Fully Integrated Microsystem For Bacterial Genotyping, Hui-Wen Chen

LSU Doctoral Dissertations

Methods for bacterial detection and identification has garnered renewed interest in recent years due to the infections they may cause and the antimicrobial resistances they can develop, the potential for bioterrorism threats and possible contamination of food/water supplies. Therefore, the rapid, specific and accurate detection of pathogens is crucial for the prevention of pathogen-related disease outbreaks and facilitating disease management as well as the containment of suspected contaminated food and/or water supplies. In this dissertation an integrated modular-based microfluidic system composed of a fluidic cartridge and a control instrument has been developed for bacterial pathogen detection. The integrated system can …


The Ecology Of Congeneric Resprouters And Reseeders (Hypericum Spp.) Along Fire-Frequented Pine Savanna Ecoclines, Raelene Marie Crandall Jan 2011

The Ecology Of Congeneric Resprouters And Reseeders (Hypericum Spp.) Along Fire-Frequented Pine Savanna Ecoclines, Raelene Marie Crandall

LSU Doctoral Dissertations

Resprouting and reseeding shrubs are predicted to be restricted to habitats with long and short return intervals of natural disturbances, respectively. Nonetheless, resprouters and reseeders co-occur along Gulf of Mexico coastal ecoclines where lightning-ignited fires were historically frequent. In this collection of studies, I examine fire responses, habitat associations, distribution limits, and seedling recruitment of Hypericum species along ecoclines in pine savannas of the St. Joe Bay State Buffer Preserve in Gulf County of Florida. In this area, ecoclines are characterized by topographic, soil moisture, and fire heterogeneity gradients. Hypericum microsepalum, an obligate resprouter, primarily resprouts following disturbances that …


Essays On The Random Parameters Logit Model, Tong Zeng Jan 2011

Essays On The Random Parameters Logit Model, Tong Zeng

LSU Doctoral Dissertations

This research uses quasi-Monte Carlo sampling experiments to examine the properties of pretest and positive-part Stein-like estimators in the random parameters logit (RPL) model based on the Lagrange Multiplier (LM), likelihood ratio (LR) and Wald tests. First, we explore the properties of quasi-random numbers, which are generated by the Halton sequence, in estimating the random parameters logit model. We show that increases in the number of Halton draws influence the efficiency of the RPL model estimators only slightly. The maximum simulated likelihood estimator is consistent and it is not necessary to increase the number of Halton draws when the sample …


Communication-Constrained Feedback Stability And Multi-Agent System Consensusability In Networked Control Systems, Laurentiu Dan Marinovici Jan 2011

Communication-Constrained Feedback Stability And Multi-Agent System Consensusability In Networked Control Systems, Laurentiu Dan Marinovici

LSU Doctoral Dissertations

With the advances in wireless communication, the topic of Networked Control Systems (NCSs) has become an interesting research subject. Moreover, the advantages they offer convinced companies to implement and use data networks for remote industrial control and process automation. Data networks prove to be very efficient for controlling distributed systems, which would otherwise require complex wiring connections on large or inaccessible areas. In addition, they are easier to maintain and more cost efficient. Unfortunately, stability and performance control is always going to be affected by network and communication issues, such as band-limited channels, quantization errors, sampling, delays, packet dropouts or …


Numerical Studies Of Flow In Porous Media Using An Unstructured Approach, Nathan Matthew Lane Jan 2011

Numerical Studies Of Flow In Porous Media Using An Unstructured Approach, Nathan Matthew Lane

LSU Doctoral Dissertations

Flow and transport in porous media is relevant to many areas of engineering and science including groundwater hydrology and the recovery of oil and gas. Porous materials are characterized by the unique shape and connectivity of the internal void structures which give rise to a large range in macroscopic transport properties. Historically an inability to accurately describe the internal pore-structure has prevented detailed study of the role of pore structure on transport. In recent decades however, the combination of high resolution imaging technologies with computational modeling has seen the development of fundamental pore-scale techniques for studying flow in porous media. …


Performing Toilets: Putting Matter Into Place, Danielle Dick Mcgeough Jan 2011

Performing Toilets: Putting Matter Into Place, Danielle Dick Mcgeough

LSU Doctoral Dissertations

In this study, I place toilets and toilet practices center stage. Each chapter begins with and is compelled by a performance event in which a toilet plays a central role, such as the display of toilets in museum settings, a festival celebrating the building of public toilet blocks, and a Big Squat event, in which people gather en masse to squat collectively for one minute in recognition of the millions that lack access to toilets. By means of performance, the toilet is transferred from the backstage to center stage. Out of place, the toilet defamiliarizes and refunctions the body’s techniques, …


Brief Interventions For Heavy College Drinkers: Randomized Clinical Trial To Investigate Comparable Efficacy Of Two Active Conditions, Magdalena Kulesza Jan 2011

Brief Interventions For Heavy College Drinkers: Randomized Clinical Trial To Investigate Comparable Efficacy Of Two Active Conditions, Magdalena Kulesza

LSU Doctoral Dissertations

Brief interventions for college heavy drinkers have shown promise in reducing drinking and related negative consequences. However, since duration of the intervention, content, method of delivery, and duration of the follow up period vary across studies, we do not know whether length of the intervention has an impact on its effectiveness. In the present study, we conducted a randomized trial systematically evaluating efficacy of two brief interventions aimed at reducing alcohol use and consequences among college student drinkers. In addition, we evaluated treatment mediators and moderators. We randomly assigned 278 heavy drinking students to a 10-minute brief intervention, a 50-minute …


Regarding Westernization In Central Africa: Hybridity In The Works Of Three Chadian Playwrights, Enoch Reounodji Jan 2011

Regarding Westernization In Central Africa: Hybridity In The Works Of Three Chadian Playwrights, Enoch Reounodji

LSU Doctoral Dissertations

The second half of the nineteenth century played a determining role in the political, economic, social, and cultural spheres of Africa. The Berlin Conference of 1884-1885 witnessed European interests bargaining over the territories of Africa and arbitrarily dividing much of the continent into different countries under European control. This historical moment may be regarded as the height of Western influence over Africa, though it only continued the colonial tradition of viewing Africa as a land without culture, theatre, literature, or history (prior to the advent of the white man). The legacy of this outlook has placed African intellectuals and literary …


Polymer Based Microfabrication And Its Applications In Optical Mems And Biomems, Guocheng Shao Jan 2011

Polymer Based Microfabrication And Its Applications In Optical Mems And Biomems, Guocheng Shao

LSU Doctoral Dissertations

Due to its ease of fabrication, low cost and great variety of functionalities, polymer has become an important material in microfabrication. MEMS devices with polymer as the structure material have found applications in various fields, especially in BioMEMS and optical MEMS. In this dissertation, three polymer based microfabricated devices/components have been developed and tested. Various polymer based fabrication techniques, such as high aspect ratio SU-8 photolithography, three dimensional polydimethylsiloxane (PDMS) soft lithography, multi-layer soft lithography and PDMS double casting technique have been developed/studied and employed in the device fabrication process. The main contribution of this dissertation includes: (1) Developed two …


Microphytobenthos Of The Northern Gulf Of Mexico Hypoxic Area And Their Role In Oxygen Dynamics, Melissa Millman Baustian Jan 2011

Microphytobenthos Of The Northern Gulf Of Mexico Hypoxic Area And Their Role In Oxygen Dynamics, Melissa Millman Baustian

LSU Doctoral Dissertations

The presence or absence of microphytobenthos on the seafloor provides clues about whether benthic oxygen evolution contributes significantly to the oxygen budget of the hypoxic area in the northern Gulf of Mexico. Hypoxia (oxygen < 2 mg l-1) creates inadequate concentrations of dissolved oxygen to support most organisms, such as fish, shrimp and crabs, and occurs over large areas of the Louisiana continental shelf from spring through summer in most years. Oxygen production by benthic autotrophs may offset a decline in oxygen concentrations if there is a functioning community and sufficient light. I sampled three stations (14, 20 and 23 m depths) ~ 100 km west of the Mississippi River over three hypoxic annual cycles (2006 – 2008), and 11 stations along a 14 - 20 m contour on the shelf in late-July in 2006, 2007 and 2008. I used microscopy and high-performance liquid chromatography to estimate the biomass and composition of phytoplankton and microphytobenthos. The potential seasonal oxygen production was estimated in 2007 and 2008 by incubating coupled light/dark sediment cores and bottom water from two stations. The sediment community (cells > 3 um) differed from those in the water column and were frequently benthic pennate diatoms and filamentous cyanobacteria (58-88% seasonally and 1-99% in mid-summer). The concentration of microphytobenthic biomass was usually < 2.0 ug g dry sed-1, and various biotic parameters were influenced by light at the seafloor. Declines in dissolved oxygen over a seasonal cycle in 2007 and 2008 were affected more by the initial dissolved oxygen concentration than by the presence of microphytobenthos that could generate oxygen. The sediment (1.2 - 27.3 mmol O2 m-2 d-1, n = 97) and bottom-water (1.1 - 17.5 mmol m-2 d-1, n = 23) oxygen consumption rates were within the range of the few previously-reported data. This work adds to these data and also provides the only sediment oxygen consumption rates at fixed sites over seasonal time scales. These results provide critical input to three-dimensional, physical-biological models of oxygen dynamics for this hypoxic area.


Marketing Forest-Based Ecotourism In Sri Lanka: Predicting The Ecotourism Behavior And Defining The Market Segment Through A Behavioral Approach, Polwattage K. Perera Jan 2011

Marketing Forest-Based Ecotourism In Sri Lanka: Predicting The Ecotourism Behavior And Defining The Market Segment Through A Behavioral Approach, Polwattage K. Perera

LSU Doctoral Dissertations

Tourism industry is one of the main drivers of the global economy and plays a key role in regional development. As negative environmental and socio-cultural impacts of mass tourism became apparent, the appeal of alternative forms of tourism, especially ecotourism, continued to gain a broad recognition. As a result, ecotourism became one of the fastest growing sectors in global tourism during the past decade. Being a fast-developing country with ample natural resources, Sri Lanka can benefit from adopting and promoting ecotourism. At present, Sri Lanka’s ecotourism resources remain largely under-utilized. With rising demand, ecotourism operators are under pressure to meet …


Writing William Burroughs, Performing The Archive, John Lebret Jan 2011

Writing William Burroughs, Performing The Archive, John Lebret

LSU Doctoral Dissertations

Between 1958 and 1972, author William S. Burroughs undertook a series of radical experiments with alternative compositional modes based on the aleatory form of the Cut-up. Burroughs sold the entirety of his work from the period, assembled into an archive, to a collector in 1972. This study uses performative writing to document a year of archival research in Burroughs' collection, currently housed by The Henry W. and Albert A. Berg Collection of English and American Literature at the New York Public Library. Melding Bakhtin's theories of the chronotope and the grotesque body with creative writing and experimental modes of scholarly …


Evaluation Of Knowledge Transfer In An Immersive Virtual Learning Environment For The Transportation Community, Mary Leah Caillier Coco Jan 2011

Evaluation Of Knowledge Transfer In An Immersive Virtual Learning Environment For The Transportation Community, Mary Leah Caillier Coco

LSU Doctoral Dissertations

In the year 2009, 667 individuals lost their lives in a highway construction or maintenance work zone (National Work Zone Safety Information Clearinghouse, 2010). Since the year 2003, 6,438 individuals have been killed in a highway construction or maintenance work zone, which is approximately 805 deaths per calendar year (National Work Zone Safety Information Clearinghouse, 2010). This eye-opening and unfortunate statistic points to the need for a re-evaluation of training methodology as it relates to work zone safety. This study reports on the use of virtual learning technology for work-zone training. This research tested the use of an Immersive Virtual …


The Effect Of Exopolymers On The Compressibility And Shear Strength Of Kaolinite, Rick Alton Nugent Jan 2011

The Effect Of Exopolymers On The Compressibility And Shear Strength Of Kaolinite, Rick Alton Nugent

LSU Doctoral Dissertations

Erosion and subsidence threaten coastal infrastructure and natural habitats throughout the coastal United States, and this threat is especially significant along the Louisiana coastline since wetland clays are generally weak and highly compressible. Hydraulic pumping of dredged sediment is a common method for combating damage caused by erosion and subsidence, but the high water content slurry deposited is very compressible with low shear strength. Although conventional soil amendments are effective for reducing compressibility and increasing shear strength, these stabilizers are often caustic or toxic, making them too risky to use. Exopolymers, however, have the potential to improve sediment stability without …


An Examination Of Errors Of Coherence In Adolescent Sentence Combining, Ginger Gunter Collins Jan 2011

An Examination Of Errors Of Coherence In Adolescent Sentence Combining, Ginger Gunter Collins

LSU Doctoral Dissertations

Young adolescents should be able to write organized multi-paragraph compositions that develop a central idea and unfold in logical and sequential order, unified through the use of transitional words and phrases. In other words, the compositions should not just consist of a string of related sentences, but represent a dynamic text that has coherence. It is important that speech-language pathologists develop quick and reliable methods for assessing coherence to aid in making data driven decisions and progress monitoring consistent with principles of Responsiveness to Intervention. Yet, the holistic quality of coherence makes it difficult to assess, both within a composition …


Spatial Ecology Of Adult Spotted Seatrout, Cynoscion Nebulosus, In Louisiana Coastal Waters, Jody Lynn Callihan Jan 2011

Spatial Ecology Of Adult Spotted Seatrout, Cynoscion Nebulosus, In Louisiana Coastal Waters, Jody Lynn Callihan

LSU Doctoral Dissertations

Spotted seatrout, Cynoscion nebulosus, are common in estuaries and coastal waters of the south Atlantic and Gulf of Mexico and are of considerable recreational and economic importance. Still, the spatial ecology of this species is under-studied and poorly resolved, especially in Louisiana waters. To address this important knowledge gap, I examined the movements, distribution, and habitat use of adult spotted seatrout in coastal Louisiana primarily using high-resolution acoustic telemetry and secondarily, conventional tagging (mark-recapture) data. At the largest spatial scale investigated, I found that adults exhibited a high degree of estuarine fidelity and rarely undertook large-scale movements in excess of …


The Relationship Between Visual Attention And Prospective Memory, Noelle L. Brown Jan 2011

The Relationship Between Visual Attention And Prospective Memory, Noelle L. Brown

LSU Doctoral Dissertations

The current study examined the role of attention in prospective memory. Prospective memory refers to the ability to form an intention to do something in the future, such as email a colleague, and additionally remembering to do so at the appropriate moment. Theories of prospective memory retrieval suggest that attention is required to complete an intention. However, the exact role of attention and whether it is always required remains unclear. One challenge in examining the allocation of attentional resources in prospective memory is that a direct measure of these resources does not exist. The current study attempted to address this …


Teaching Tactual Discrimination Of Braille Characters To Beginning Braille Readers, Karen A. Toussaint Jan 2011

Teaching Tactual Discrimination Of Braille Characters To Beginning Braille Readers, Karen A. Toussaint

LSU Doctoral Dissertations

We taught three children with visual impairments to make tactual discriminations of the braille alphabet within a matching-to-sample format. That is, we presented participants with a braille character as a sample stimulus and they were to select the matching stimulus from an array of three comparisons. In order to minimize participant errors, we arranged braille characters into training sets in which the target and non-target stimuli in the comparison arrays were initially maximally different in terms of the number of dots comprising each character. As participants mastered these discriminations, we then increased the similarity between target and non-target comparisons (i.e., …


Calcium-Dependent Mechanisms In The Chicken Retina, Merve Tekmen Jan 2011

Calcium-Dependent Mechanisms In The Chicken Retina, Merve Tekmen

LSU Doctoral Dissertations

Multiple classes of retinal amacrine cells use L-type Ca2+ channels to mediate synaptic transmission. I have used whole cell voltage clamp recordings from primary cultures of amacrine cells to investigate the regulation of these channels. In this study, I show that inhibiting mitochondrial calcium uptake (MCU) caused a reversible reduction in the Ca2+ current amplitude. Replacing external Ca2+ with Ba2+ minimized the effects of blocking MCU indicating that the Ca2+ influx is the primary source of the inhibition. With 1,2-bis-(o-aminophenonxy)ethane-N,N,N’,N’-tetraacetic acid (BAPTA) in the recording pipette, MCU inhibition caused an increase in the current amplitude indicating that the fast buffering …


Capturing Elements In Matroid Minors, Deborah Chun Jan 2011

Capturing Elements In Matroid Minors, Deborah Chun

LSU Doctoral Dissertations

In this dissertation, we begin with an introduction to a matroid as the natural generalization of independence arising in three different fields of mathematics. In the first chapter, we develop graph theory and matroid theory terminology necessary to the topic of this dissertation. In Chapter 2 and Chapter 3, we prove two main results. A result of Ding, Oporowski, Oxley, and Vertigan reveals that a large 3-connected matroid M has unavoidable structure. For every n exceeding two, there is an integer f(n) so that if |E(M)| exceeds f(n), then M has a minor isomorphic to the rank-n wheel or whirl, …


Differences Across Racial Groups In Caregiver Ratings Of Symptoms In Children Diagnosed With Autism Spectrum Disorders, Cindy Terlonge Graham Jan 2011

Differences Across Racial Groups In Caregiver Ratings Of Symptoms In Children Diagnosed With Autism Spectrum Disorders, Cindy Terlonge Graham

LSU Doctoral Dissertations

A great deal of attention from local, federal, and international communities has been focused on autism spectrum disorders (ASDs). As the prevalence of these disorders rise, researchers continue to investigate various unanswered questions. The goal of this study was to examine the differences across racial/ethnic groups in caregiver ratings of symptoms of children diagnosed with ASDs. Results from such research will help determine whether cultural background can influence the recognition of behaviors indicative of an ASD. Culturally-sensitive clinical practice stemming from the significant findings of this research project can help to reduce the age at which minority children are diagnosed. …


Characterization Of Novel Akermanite:Poly-E-Caprolactone Scaffolds For Bone Tissue Engineering Aapplications Combined With Human Adipose-Derived Stem Cells, Andre S. Zanetti Jan 2011

Characterization Of Novel Akermanite:Poly-E-Caprolactone Scaffolds For Bone Tissue Engineering Aapplications Combined With Human Adipose-Derived Stem Cells, Andre S. Zanetti

LSU Doctoral Dissertations

The development of porous materials useful as scaffolds for the sustained three-dimensional (3D) growth of human adipose-derived stem cells (hASC) is of particular interest to facilitate healing after musculoskeletal injuries. In this study, a composite porous material obtained by blending akermanite with poly-e-caprolactone (PCL) is proposed as novel alternative to bone tissue regeneration. The objectives of this study are (1) to characterize the akermanite:PCL scaffold properties; (2) to investigate the in vitro osteogenic potential of hASC loaded to optimal akermanite:PCL scaffolds; (3) to assess the metabolic activity and osteogenesis of hASC loaded to optimal akermanite:PCL scaffolds post-thawing using optimal cryopreservation …


Decoupling User Interface Design Using Libraries Of Reusable Components, Rajesh Sankaran Jan 2011

Decoupling User Interface Design Using Libraries Of Reusable Components, Rajesh Sankaran

LSU Doctoral Dissertations

The integration of electronic and mechanical hardware, software and interaction design presents a challenging design space for researchers developing physical user interfaces and interactive artifacts. Currently in the academic research community, physical user interfaces and interactive artifacts are predominantly designed and prototyped either as one-off instances from the ground up, or using functionally rich hardware toolkits and prototyping systems. During this prototyping phase, undertaking an integral design of the interface or interactive artifact’s electronic hardware is frequently constraining due to the tight couplings between the different design realms and the typical need for iterations as the design matures. Several current …


Examining The Perceptions Of Teachers' Efficacy In Handling Student Misbehavior (Tehsm) In Classroom And Physical Education Settings, Costas Nicou Tsouloupas Jan 2011

Examining The Perceptions Of Teachers' Efficacy In Handling Student Misbehavior (Tehsm) In Classroom And Physical Education Settings, Costas Nicou Tsouloupas

LSU Doctoral Dissertations

Research has found dealing with student misbehavior as the most prominent source associated with teachers’ negative behavioral outcomes at work. One approach for understanding teachers’ behavioral responses to student misbehavior is through the efficacy beliefs of teachers. This line of inquiry has lead to the advancement of the concept of teacher efficacy in handling student misbehavior or TEHSM. TEHSM was found to significantly and negatively mediate the relationship between teachers’ perception of student misbehavior, emotional exhaustion, and turnover intentions respectively. To date, limited information is available regarding the makeup of TEHSM which gives emphasis to the significance of this dissertation. …


Fatalities Due To Hurricane Katrina's Impacts In Louisiana, Ezra Clay-Kelly Boyd Jan 2011

Fatalities Due To Hurricane Katrina's Impacts In Louisiana, Ezra Clay-Kelly Boyd

LSU Doctoral Dissertations

This dissertation presents a comprehensive analysis of the loss of life in Louisiana associated with Hurricane Katrina and the catastrophic failure of the federal hurricane protection system. While Louisiana officials attribute 1,464 deaths to this disaster, a Louisiana Katrina Victim Database compiled for this dissertation lists 1,575 victims whose death can be linked to circumstances related to the disaster. First, this dissertation presents a comprehensive assessment of the multiple hazards impacting a dynamic population within southeast Louisiana. This is followed by a comprehensive descriptive analysis of victims’ characteristics. Both of these assessments point to an important conclusion: circumstances matter in …


Effects Of Ecotourist Pre-Purchase And External Information Search Behaviors And Strategies On Forest-Based Ecotourism Travel Decisions In Sri Lanka, Rangika T. Perera Jan 2011

Effects Of Ecotourist Pre-Purchase And External Information Search Behaviors And Strategies On Forest-Based Ecotourism Travel Decisions In Sri Lanka, Rangika T. Perera

LSU Doctoral Dissertations

In the 1980s, the term ecotourism emerged as a direct result of acknowledgment and reaction by travelers to global ecological practices. In reality, the concept of ecotourism carries wide applications, particularly for bio-diverse countries with unique natural attractions. Sri Lanka qualified as such a country, presenting a significant tourism resource base, that display natural and cultural phenomena, including forests, waterfalls, mountains, exotic flora and fauna, and a heritage equally as ancient and as rich as the Greeks and Romans. Ecotourism in today’s dynamic global environment demands that ecotourism operators face a keenly competitive market in order to present an appealing …


Synthesis, Biological And Photophysical Studies Of Novel Compounds For Cancer Therapy, Edith Khavwajira Amuhaya Jan 2011

Synthesis, Biological And Photophysical Studies Of Novel Compounds For Cancer Therapy, Edith Khavwajira Amuhaya

LSU Doctoral Dissertations

Cancer remains the second most common cause of death in the United States. It is therefore imperative that a lot of effort be put into finding a cure for this dreadful disease that shows no discrimination, and virtually anybody is at risk of developing the disease. Chapter 1 introduces basic facts about cancer and the available treatments, including PDT and BNCT. Our focus will be on these two bimodal therapies, which form the basis of my research work, which involves the synthesis of potential sensitizers to be used either in PDT or BNCT or both. In Chapter 2, I discuss …