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Articles 1 - 30 of 249
Full-Text Articles in Entire DC Network
Remote Assessment And Management Of Physical Function In Older Adults (Ramp): An International Expert Delphi Process, Jack Dalla Via, Hurst, Elsa Dent, Jackson J. Fyfe, Paul Jansons, Eleanor J. Hayes, Marc Sim, Mylene Aubertin-Leheudre, Alex Barreto De Lima, Lucimere Bohn, Sabine Britting, Fanny Buckinx, Gavin Connolly, Lora Giangregorio, Duarte Henriques-Neto, Jennifer R.A. Jones, Robert Kob, Suzanne N. Morin, Girish N, Lucas B.R. Orssatto, Maria Pearson, Daniel Pinto, Esmee M. Reijnierse, Catherine M. Said, Mohamed Salem, Gary Skinner
Remote Assessment And Management Of Physical Function In Older Adults (Ramp): An International Expert Delphi Process, Jack Dalla Via, Hurst, Elsa Dent, Jackson J. Fyfe, Paul Jansons, Eleanor J. Hayes, Marc Sim, Mylene Aubertin-Leheudre, Alex Barreto De Lima, Lucimere Bohn, Sabine Britting, Fanny Buckinx, Gavin Connolly, Lora Giangregorio, Duarte Henriques-Neto, Jennifer R.A. Jones, Robert Kob, Suzanne N. Morin, Girish N, Lucas B.R. Orssatto, Maria Pearson, Daniel Pinto, Esmee M. Reijnierse, Catherine M. Said, Mohamed Salem, Gary Skinner
Research outputs 2022 to 2026
Background: Remote methods may help older adults improve their physical function, but understanding the perspectives of experts who deliver this care is critical. This modified Delphi process aimed to develop expert consensus on effectiveness, feasibility and implementation of remote assessment and management of physical function in older adults. Methods: This online Delphi process included experts involved in supporting older adults to maintain or improve their health. The Round 1 survey presented 33 Delphi statements assessed using an 11-point Likert scale (0–10; ≥7 indicated agreement). Statements with strong (≥80 %), moderate (50–<80 %) and low (<50 %) agreement were accepted, revised, or rejected, respectively. Revised statements were presented in Round 2, and accepted statements were consolidated into key messages. Results: In total, 108 respondents (67 % female; mean [SD] age 41.4 [10.9] years) from 16 countries (five continents) completed Round 1. Fourteen statements were accepted (88–100 % agreement) and 10 were rejected (8–39 % agreement). The remaining nine statements (52–69 % agreement) were revised, and two new statements were developed for Round 2, which was completed by 89 (82 %) respondents. Five Round 2 statements were accepted (82–93 % agreement). Seven key messages were developed from 19 accepted statements, highlighting that remote care should be accessible to older adults with requisite capabilities, is feasible for older adults and health professionals with adequate support and training, and requires guidelines, policies, and further research to support wider adoption. Conclusions: The findings of this Delphi process can inform the implementation of remote care approaches for assessing and managing physical function in older adults.
The Crossroads Between Osteosarcopenia And Intrinsic Capacity—A Narrative Review, Nailton J. Neto, Guy Hajj-Boutros, Wayne Lok Ok Choo, Miguel G. Borda, Konstantinos Prokopidis, Hassan Rammal, Daniel Rivas, Hussein Samhat, Ivan Baltasar-Fernandez, Mahdi Imani, Cristiano Dos Santos Gomes, Oscar Rosas Carrasco, Marc Sim, Julie A. Pasco, Julia Chabot, Ana M. Ayala-Copete, Francisco J. García-García, Claire Godard-Sebillotte, Raman Agnihotram, Lana J. Williams, Anna Andrianova, Robinson Ramirez-Vélez, Emma Connolly, Harmehr Sekhon, Hidenori Arai, Liang-Kung Chen, Andréa Faust, Howard Bergman, Alexandra Papaioannou, Pierrette Gaudreau, Tiago Alexandre, Leocadio Rodriguez-Mañas, Ricardo Oliveira Guerra, Gustavo Duque
The Crossroads Between Osteosarcopenia And Intrinsic Capacity—A Narrative Review, Nailton J. Neto, Guy Hajj-Boutros, Wayne Lok Ok Choo, Miguel G. Borda, Konstantinos Prokopidis, Hassan Rammal, Daniel Rivas, Hussein Samhat, Ivan Baltasar-Fernandez, Mahdi Imani, Cristiano Dos Santos Gomes, Oscar Rosas Carrasco, Marc Sim, Julie A. Pasco, Julia Chabot, Ana M. Ayala-Copete, Francisco J. García-García, Claire Godard-Sebillotte, Raman Agnihotram, Lana J. Williams, Anna Andrianova, Robinson Ramirez-Vélez, Emma Connolly, Harmehr Sekhon, Hidenori Arai, Liang-Kung Chen, Andréa Faust, Howard Bergman, Alexandra Papaioannou, Pierrette Gaudreau, Tiago Alexandre, Leocadio Rodriguez-Mañas, Ricardo Oliveira Guerra, Gustavo Duque
Research outputs 2022 to 2026
Intrinsic capacity (IC) is defined as the composite of physical and mental abilities an individual possesses, encompassing 5 domains: cognition, psychological health, sensory function, vitality, and locomotion. This construct is central to the World Health Organization’s framework for assessing functional ability in older adults. Growing evidence highlights the critical role of the musculoskeletal system in maintaining these domains, while conditions such as sarcopenia, osteoporosis, and their coexistence as osteosarcopenia (OS) are increasingly associated with IC decline. This narrative review compiles current evidence on the modulatory role of muscles and bones in IC and the impacts of sarcopenia, osteoporosis, and OS. …
The Interplay Between Osteosarcopenia And Intrinsic Capacity: Insights And Associations With All-Cause Mortality In The Toledo Study For Healthy Aging, Ivan Baltasar-Fernandez, Pedro L. Valenzuela, Irene Rodríguez-Gómez, Fabio Quiñonez-Bareiro, Luis M. Alegre, Konstantinos Prokopidis, Leocadio Rodriguez-Mañas, Ignacio Ara, Oscar Rosas-Carrasco, Lana J. Williams, Robinson Ramirez-Vélez, Julie A. Pasco, Guy Hajj-Boutros, Raman Agnihotram, Marc Sim, Wayne Lok Ok Choo, Mahdi Imani, Ana M. Ayala-Copete, Julia Chabot, Miguel G. Borda, Nailton J. Neto, Claire Godard-Sebillotte, Howard Bergman, Anna Andrianova, Hidenori Arai, Pierrette Gaudreau
The Interplay Between Osteosarcopenia And Intrinsic Capacity: Insights And Associations With All-Cause Mortality In The Toledo Study For Healthy Aging, Ivan Baltasar-Fernandez, Pedro L. Valenzuela, Irene Rodríguez-Gómez, Fabio Quiñonez-Bareiro, Luis M. Alegre, Konstantinos Prokopidis, Leocadio Rodriguez-Mañas, Ignacio Ara, Oscar Rosas-Carrasco, Lana J. Williams, Robinson Ramirez-Vélez, Julie A. Pasco, Guy Hajj-Boutros, Raman Agnihotram, Marc Sim, Wayne Lok Ok Choo, Mahdi Imani, Ana M. Ayala-Copete, Julia Chabot, Miguel G. Borda, Nailton J. Neto, Claire Godard-Sebillotte, Howard Bergman, Anna Andrianova, Hidenori Arai, Pierrette Gaudreau
Research outputs 2022 to 2026
Background: Osteosarcopenia—the coexistence of osteopenia/osteoporosis and sarcopenia—is associated with numerous adverse health outcomes, but its association with intrinsic capacity (IC) remains unknown. We aimed to explore the associations of osteosarcopenia with IC and all-cause mortality in older adults. Methods: We conducted a cross-sectional analysis of IC and a prospective analysis of all-cause mortality in 1142 participants from the Toledo Study for Healthy Aging (75.1 ± 6.0 years, 53.1% women). Participants were classified as having no musculoskeletal disorders, osteopenia/osteoporosis, sarcopenia, or osteosarcopenia (DXA- and EWGSOP2-based criteria). IC was operationalized as a composite score integrating locomotion, cognition, psychological, vitality, and sensory domains. …
Beyond The First Bout: Adaptations To Repeated Injuries Across Physiological And Pathological Conditions, Cory W. Baumann, Christopher P. Ingalls, Kazunori Nosaka, Jarrod A. Call
Beyond The First Bout: Adaptations To Repeated Injuries Across Physiological And Pathological Conditions, Cory W. Baumann, Christopher P. Ingalls, Kazunori Nosaka, Jarrod A. Call
Research outputs 2022 to 2026
Skeletal muscle exhibits remarkable plasticity following injury, yet most research has focused on responses to a single bout of eccentric contractions. This review addresses adaptations to repeated eccentric contraction–induced injuries across physiological and pathological conditions, with emphasis on insights from preclinical rodent models. In healthy muscle, the repeated bout effect (RBE) reduces strength loss and accelerates recovery after subsequent bouts. However, these adaptations are highly condition dependent. Aging can attenuate the RBE, while dystrophic muscle remains vulnerable to repeated injury despite compensatory remodeling. Other factors, including but not limited to, chronic alcohol intake and malignant hyperthermia can influence these responses, …
Growing Older Across Time And Space: The Impact Of Various Forms Of Capital On Social Support Networks Among Older Vietnamese Migrants, Hien Thi Nguyen, Lukasz Krzyzowski, Loretta Baldassar
Growing Older Across Time And Space: The Impact Of Various Forms Of Capital On Social Support Networks Among Older Vietnamese Migrants, Hien Thi Nguyen, Lukasz Krzyzowski, Loretta Baldassar
Research outputs 2022 to 2026
Much has been written about the important role of social support networks (SSNs) for the well-being of older adults, encompassing their social, emotional and practical needs. Less is known about what happens to the SSNs of older people when they migrate, and even fewer studies have examined the impact of different forms of capital on these networks. Drawing on ethnographic interviews and participant observation with 22 older Vietnamese migrants in Australia (2020–21), this paper explores the influence of different forms of social, cultural, economic and symbolic capital on their SSNs. Data analysis comprised egocentric social network analysis of the connections …
Disuse-Induced Muscle Atrophy And Muscle Weakness From Hospitalization To Spaceflight: Exercise Succeeds In Prevention And Treatment—A Meta-Analysis, Camila S. Padilha, Figueiredo, Rafael Deminice, S. Ribeiro, Robert U. Newton, Nicolas H. Hart, José Cesar Rosa-Neto, Marília Seelaender, Fábio Santos Lira
Disuse-Induced Muscle Atrophy And Muscle Weakness From Hospitalization To Spaceflight: Exercise Succeeds In Prevention And Treatment—A Meta-Analysis, Camila S. Padilha, Figueiredo, Rafael Deminice, S. Ribeiro, Robert U. Newton, Nicolas H. Hart, José Cesar Rosa-Neto, Marília Seelaender, Fábio Santos Lira
Research outputs 2022 to 2026
Background: Exercise has been proposed as both a preventive and therapeutic countermeasure; however, its effectiveness across different disuse conditions and timings of implementation remains uncertain. Methods: This systematic review and meta-analysis (PROSPERO: CRD42021256599) searched ClinicalTrials.gov, Cochrane Central, PubMed, SPORTDiscus, Web of Science, Scopus, CINAHL and SciELO from inception to May 2021, with an update in March 2025. Randomized and nonrandomized controlled trials examining exercise interventions during or after muscle disuse were included according to the PICOS framework. Random-effects meta-analysis evaluated effects on muscle strength, power and mass across hospitalization, bed rest and spaceflight conditions. Effect sizes (ES) are reported as …
Comment On ‘Muscle-Specific Strength Better Predicts Physical Performance Decline Than Conventional Metrics: The I-Lan Longitudinal Aging Study’ By Chien Et Al., Ricardo M. Lima, Anthony J. Blazevich
Comment On ‘Muscle-Specific Strength Better Predicts Physical Performance Decline Than Conventional Metrics: The I-Lan Longitudinal Aging Study’ By Chien Et Al., Ricardo M. Lima, Anthony J. Blazevich
Research outputs 2022 to 2026
No abstract provided.
High-Sensitivity Cardiac Troponin I And Frailty: Associations With The Frailty Index And Fried Phenotype In Older Women, Jedd Pratt, Abadi K. Gebre, Carlos J. Toro-Huamanchumo, Elsa Dent, Trent Bozanich, Wai E. Lim, Elizabeth Byrnes, Julee Mcdonagh, Caleb Ferguson, Craig Sale, Kun Zhu, Carl Schultz, Richard L. Prince, Joshua R. Lewis, Marc Sim
High-Sensitivity Cardiac Troponin I And Frailty: Associations With The Frailty Index And Fried Phenotype In Older Women, Jedd Pratt, Abadi K. Gebre, Carlos J. Toro-Huamanchumo, Elsa Dent, Trent Bozanich, Wai E. Lim, Elizabeth Byrnes, Julee Mcdonagh, Caleb Ferguson, Craig Sale, Kun Zhu, Carl Schultz, Richard L. Prince, Joshua R. Lewis, Marc Sim
Research outputs 2022 to 2026
Despite the nexus between cardiovascular health and frailty, the relevance of high-sensitivity cardiac troponin I (hs-cTnI), a biomarker of myocardial injury, to frailty is poorly understood. We examined whether hs-cTnI concentrations were associated with frailty in a well-characterized cohort of older women. A total of 1151 community-dwelling women from the Perth Longitudinal Study of Aging Women (mean age ± SD = 75.2 ± 2.7 years) were included. Frailty was operationalized using a validated frailty index (FI) of cumulative deficits and a modified Fried phenotype. Plasma hs-cTnI were categorized into quartiles. Cross-sectional associations between hs-cTnI quartiles and frailty were assessed using …
Barriers And Facilitators To Recruiting Older Adult Care Homeresidents Into Clinical Trials Of Medicines And Vaccines: A Scoping Review, Selvarani Subbarayan, Imogen A. Smith-Dodd, Gabriel Nicolson, Jennifer K. Burton, Janet T. Scott, Seshadri S. Vasan, Susan D. Shenkin, Roy L. Soiza, The Watch Consortium
Barriers And Facilitators To Recruiting Older Adult Care Homeresidents Into Clinical Trials Of Medicines And Vaccines: A Scoping Review, Selvarani Subbarayan, Imogen A. Smith-Dodd, Gabriel Nicolson, Jennifer K. Burton, Janet T. Scott, Seshadri S. Vasan, Susan D. Shenkin, Roy L. Soiza, The Watch Consortium
Research outputs 2022 to 2026
Introduction: Excluding Care Home (CH) residents from clinical trials of medicines and vaccines has led to an evidence gap. Findings from younger adults may not be generalisable to CH residents with frailty and dementia. Therefore, it is essential to evaluate pharmacological treatments directly in CH residents to assess their safety and efficacy.
Methods: As part of the Widening Access to Trials in Care Homes project, we conducted a scoping review using Joanna Briggs Institute methodology to identify barriers and facilitators to recruiting CH residents into clinical trials of medicinal products. We searched EMBASE, MEDLINE, PsycINFO, CINAHL, and the Cochrane Library …
A Biographic-Narrative Of The Masquerade Collections Of Alhassan Mahamudu Saliga: Reechoing The Textile Art Future, Kweku Safo-Ankama, Enock Swanzy-Impraim
A Biographic-Narrative Of The Masquerade Collections Of Alhassan Mahamudu Saliga: Reechoing The Textile Art Future, Kweku Safo-Ankama, Enock Swanzy-Impraim
Research outputs 2022 to 2026
This study explores the biographical narratives of Alhassan Mahamudu Saliga’s masquerade collections. It examines his innovative textile art practices and their integration into Winneba masquerade culture. An in-depth narrative analysis was employed to interpret and construct his life story, facilitating an understanding of biographical data. The researchers employed interviews, observations, and document reviews as data collection instruments. The interviews focused on four key aspects: design concepts, construction techniques, material selection, and the benefits of using recycled materials. The findings revealed that Alhassan Mahamudu Saliga has been a prominent masquerade costume designer from 1984 to 2025. It was discovered that the …
Modifiable Risk Factors And Hearing Loss: The National Health And Nutrition Examination Survey 1999–2020, Yulu Zheng, Tingting Li, Zhiyuan Wu, Yahong Zhu, Zheng Guo, Xingang Li
Modifiable Risk Factors And Hearing Loss: The National Health And Nutrition Examination Survey 1999–2020, Yulu Zheng, Tingting Li, Zhiyuan Wu, Yahong Zhu, Zheng Guo, Xingang Li
Research outputs 2022 to 2026
Objective: To explore the associations between major modifiable risk factors and hearing loss.
Methods: This serial cross-sectional study was conducted within the National Health and Nutrition Examination Survey 1999–2020 in the United States. Associations were assessed using modified Poisson regression and within-sample population attributable fraction (PAF).
Results: Eight thousand seven hundred and seventy adults aged 40–85 years were included in the analyses, the mean (SD) age was 58.0 (11.7) years, with 4002 men (45.6%). Hearing loss was associated with low educational attainment with prevalence ratio 1.23, 95% confidence interval (1.15, 1.31); low income 1.11 (1.04, 1.19); diabetes 1.10 (1.03, 1.18); …
I Am Still Concerned About Them: Grandmother Kinship Caregivers And The Challenge Of Abuse By Children In Their Care, Hajara Bentum, Vicki Banham, Kwadwo Adusei-Asante
I Am Still Concerned About Them: Grandmother Kinship Caregivers And The Challenge Of Abuse By Children In Their Care, Hajara Bentum, Vicki Banham, Kwadwo Adusei-Asante
Research outputs 2022 to 2026
Research evidence has shown that adverse occurrences within the kinship caregiving environment, such as the grandparents' experiences of violence and abuse, may introduce new stressors or exacerbate existing aged-related challenges, leading to adverse impacts on grandparent kinship carers. Yet no research has explored the impact of abuse and violence experienced by grandparent kinship caregivers from children in their care. This study involved narrative interviews with 31 grandmother kinship caregivers in Ghana to explore the adverse effects of the abuse they have experienced from children in their care. The study findings revealed the following impacts on grandmothers: (1) high blood pressure, …
Where’S My Tweed Jacket With Leather Elbow Patches? The Challenges Of Aging Gracefully In Higher Education, John A. O’Rourke, Christina Gray
Where’S My Tweed Jacket With Leather Elbow Patches? The Challenges Of Aging Gracefully In Higher Education, John A. O’Rourke, Christina Gray
Research outputs 2022 to 2026
This paper presents an examination of one veteran academics’ experience in higher education. Via an autoethnographic reflection of a two-decade career, the work-related situations that impact on job enjoyment and challenge motivation to bring enthusiasm year-after-year are discussed. Veteran academics have seen higher education transform dramatically during their tenure and the pressure points that impact on wellbeing are discussed and aligned to contemporary research. In response to the challenges associated with aging in higher education, this paper examines how veteran academics need to prioritize self-care and explores ways that universities can maximize the accumulated knowledge and pedagogical skillset of these …
Configurations Of Work Design: A Person-Centered Perspective Of Job Demands And Resources In The Healthcare Sector, Arian Kunzelmann, Mina Askovic, Vivien W. Forner, Nate Zettna, Anupama Jolly, Shanta Dey, Helena Nguyen, Anya Johnson, Sharon K. Parker
Configurations Of Work Design: A Person-Centered Perspective Of Job Demands And Resources In The Healthcare Sector, Arian Kunzelmann, Mina Askovic, Vivien W. Forner, Nate Zettna, Anupama Jolly, Shanta Dey, Helena Nguyen, Anya Johnson, Sharon K. Parker
Research outputs 2022 to 2026
Work design is fundamental Human Resource Management (HRM) responsibility, which is crucial for employee well-being. Current HRM research on work design largely relies on variable-centered approaches. We argue that a person-centered approach uncovers more complex interaction patterns that are often obscured and provides a more holistic view of work design. Additionally, work design research often neglects occupational specificity, focusing on universal work characteristics. While this is important for generalizability, it can miss important industry and occupational variations, such as in healthcare. In this research, we focus on both universal work characteristics (feedback, autonomy, and support) and a dominant occupation-specific work …
Feasibility And Preliminary Efficacy Of Integrative Neuromuscular Training For Childhood Cancer Survivors: A Pilot Study, Anna Maria Markarian, U. Newton, Dennis Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle-Mcintyre, Jodie Cochrane Wilkie, Daniel A. Galvão
Feasibility And Preliminary Efficacy Of Integrative Neuromuscular Training For Childhood Cancer Survivors: A Pilot Study, Anna Maria Markarian, U. Newton, Dennis Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle-Mcintyre, Jodie Cochrane Wilkie, Daniel A. Galvão
Research outputs 2022 to 2026
Background: Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long-term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during critical developmental periods. Methods: Eight children treated for ALL (aged 6–12 years) completed a supervised INT intervention (2 sessions/week for 8 weeks). Primary outcomes were feasibility (recruitment, retention, adherence, compliance, and tolerance) and program acceptability. Secondary outcomes included muscle function (isometric midthigh pull [IMTP], countermovement jump, and handgrip strength), dual-energy x-ray absorptiometry (DXA)-derived body composition, peripheral quantitative computed …
Non-Pharmacological Sleep Interventions For Dementia Caregivers: A Systematic Review Of Randomized Controlled Trials, Aisling Smyth, Lambert, Mark Jenkins, Adugnaw Zeleke Alem, Misganaw Gebrie Worku, Sujatha Shanmugasundaram
Non-Pharmacological Sleep Interventions For Dementia Caregivers: A Systematic Review Of Randomized Controlled Trials, Aisling Smyth, Lambert, Mark Jenkins, Adugnaw Zeleke Alem, Misganaw Gebrie Worku, Sujatha Shanmugasundaram
Research outputs 2022 to 2026
Background: Caregivers of people living with dementia frequently report poor sleep. This systematic review describes evidence from randomised controlled trials of non-pharmacological sleep interventions for dementia carers. Methods: A systematic search of major databases was undertaken. Risk of bias was assessed using the Cochrane ROB 2.0 tool. Narrative synthesis followed Synthesis Without Meta-analysis (SWiM) guidelines due to substantial heterogeneity. Findings: Eighteen articles were included. Risk of Bias analyses revealed most studies had high overall risk of bias, primarily from selection of reported result bias. Interventions comprised of five categories: sleep-promoting, carer well-being, exercise, technology-based and complementary therapy. High variability between …
Do Lineage-Based Inheritance Norms Matter In Kinship Care Arrangements? Exploring Inheritance Paths In Grandparent Kinship Care Practice In Ghana, Hajara Bentum, Alhassan Abdullah, Vicki Banham, Kwadwo Adusei-Asante
Do Lineage-Based Inheritance Norms Matter In Kinship Care Arrangements? Exploring Inheritance Paths In Grandparent Kinship Care Practice In Ghana, Hajara Bentum, Alhassan Abdullah, Vicki Banham, Kwadwo Adusei-Asante
Research outputs 2022 to 2026
Kinship lineage and inheritance norms in Ghana play a significant role in shaping family decisions. Research has shown that kinship lineage and inheritance norms determine kin membership for children by specifying whether they belong to their maternal or paternal family, as well as whether they can inherit properties of their biological father or mother. The notion of kinship membership has shaped parenting and child welfare practices in Ghana, including child maintenance payments and parental neglectful behaviours. This research explored whether kinship-based inheritance norms could influence decisions about selecting a grandmother (maternal vs. paternal grandmother) as a child’s caregiver. We interviewed …
Brilliant Little Things: Drama-Based Mindfulness To Support Pre-Service Teacher Wellbeing, Christina C. Gray, John O’Rourke
Brilliant Little Things: Drama-Based Mindfulness To Support Pre-Service Teacher Wellbeing, Christina C. Gray, John O’Rourke
Research outputs 2022 to 2026
Wellbeing is increasingly recognised as a critical concern in teacher education, yet pre-service teachers remain vulnerable to stress, burnout, and early attrition. This study examines Brilliant Little Things, an arts-based wellbeing initiative embedded within a drama education program. Using a phenomenological approach, the research draws on interviews, reflective journals, group chat posts, photographs, and artwork to explore how drama-based mindfulness practices can support the wellbeing of drama educators. Findings reveal how the production fostered reflection, connection, and emotional insight, offering a space for mindfulness and community. Narratives highlight the value of creative, relational pedagogies in strengthening resilience. This research contributes …
Compassionate Communities, Māori Ageing And End-Of-Life: A Systematic Review, Melissa Carey, Kathleen Mason, Levi Fox, Tess Moeke-Maxwell, Merryn Gott
Compassionate Communities, Māori Ageing And End-Of-Life: A Systematic Review, Melissa Carey, Kathleen Mason, Levi Fox, Tess Moeke-Maxwell, Merryn Gott
Research outputs 2022 to 2026
Background: Māori people in Aotearoa New Zealand and Australia experience significant healthcare inequity as they age and towards the end of their lives. Compassionate community approaches to ageing and end-of-life care are increasing in popularity throughout the world. However, this approach has arisen from Eurocentric knowledge systems and not from First Nations people and their communities. Objectives: This research aimed to gain insight into what the Compassionate Communities approach means for First Nations people and identify implications for Māori in Aotearoa New Zealand and Australia. A systematic literature review explored the intersection of Compassionate Communities and First Nations peoples’ perspectives …
Intravenous Infusion Of Nicotinamide Adenine Dinucleotide (Nad+) Versus Nicotinamide Riboside (Nr): A Retrospective Tolerability Pilot Study In A Real-World Setting, Kirsten Reyna, Greer Heinzen, Nikita Patel, Marie Ritter, Alexandra Siojo, Henry Legere, Rachele Pojednic
Intravenous Infusion Of Nicotinamide Adenine Dinucleotide (Nad+) Versus Nicotinamide Riboside (Nr): A Retrospective Tolerability Pilot Study In A Real-World Setting, Kirsten Reyna, Greer Heinzen, Nikita Patel, Marie Ritter, Alexandra Siojo, Henry Legere, Rachele Pojednic
Research outputs 2022 to 2026
Background: Nicotinamide adenine dinucleotide (NAD+) is a cofactor for NAD+-dependent enzymes that regulate DNA repair, cellular metabolism, and immune function. Supplementation with NAD+ and its precursors is commonly used to prevent age-related disease and extend healthspan. Commercial clinical and wellness settings increasingly provide intravenous (IV) NAD+ and nicotinamide riboside (NR) despite limited evaluation of safety and effectiveness. These considerations are important, as NAD+ and its precursors differ in reported side effects, cellular uptake, and metabolism. This study sought to compare commercially administered NAD+ IV and NR IV in humans by evaluating infusion …
When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes At Aβ-Pet Centiloid 15, Mean Age Of 66 Years, Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey-Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph Martins, Colin L. Masters, James Doecke
When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes At Aβ-Pet Centiloid 15, Mean Age Of 66 Years, Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey-Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph Martins, Colin L. Masters, James Doecke
Research outputs 2022 to 2026
Objective: Sporadic late-onset Alzheimer's disease (AD) is characterized by a long pre-clinical phase where amyloid-beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ-PET) and plasma Aβ42/40 become abnormal. Methods: Two high performance immunoprecipitation-mass spectrometry (IP-MS) assays (WashU/C2N and Shimadzu) were tested on samples from 1,450 participants who were diagnosed as cognitively unimpaired (CU), mild cognitive impairment (MCI), or AD-dementia across 4 international cohorts. Natural history modeling and trajectory analyses of the combined Aβ-PET …
Providing Help In Europe: Are In-Household Care And Outside-Household Support Associated With Grandparental Child Care?, Roosa Maria Savela, David A. Coall, Mirkka Danielsbacka, Antti O. Tanskanen
Providing Help In Europe: Are In-Household Care And Outside-Household Support Associated With Grandparental Child Care?, Roosa Maria Savela, David A. Coall, Mirkka Danielsbacka, Antti O. Tanskanen
Research outputs 2022 to 2026
Grandparental child care is a vital form of social support that can enhance family well-being. Prior studies have found that older adults who provide support to one individual are more likely to offer help to others within their families and social networks. However, little research has examined whether helping others is associated with grandparental child care. Using data from the Survey of Health, Aging and Retirement in Europe, covering 27 countries, and using multinomial regression models, we show that (a) support provided to individuals outside the household is associated with increased grandparental child care, whereas (b) family care provided within …
Promoting The Concept Healthy Ageing For Use In Gerontological Health And Social Care Policy And Practice, Claire Donnellan
Promoting The Concept Healthy Ageing For Use In Gerontological Health And Social Care Policy And Practice, Claire Donnellan
Research outputs 2022 to 2026
Aims: The concept of healthy or successful ageing dates back to the 1960s, where its goal is more realistic in today's ageing society as a result of effective interventions to control and reduce disability and health risks. The aim of this paper is to outline the importance of defining ageing, the semantics and indicators used, and to identify common challenges for health professionals' understanding and application of a healthy ageing approach in their everyday clinical practice. Design and Methods: This discursive paper demonstrates how realistic ageing indicators are for highlighting the variation and impact of challenges associated with ageing. It …
Patients’ And Health Professionals’ Perspectives On Transforming The Burden Of Haemodialysis (Hd) Treatment To An Opportunity: An In-Depth Qualitative Investigation, Haseeba Shouket, Eyal Gringart, Deirdre Drake, Ulrich Steinwandel
Patients’ And Health Professionals’ Perspectives On Transforming The Burden Of Haemodialysis (Hd) Treatment To An Opportunity: An In-Depth Qualitative Investigation, Haseeba Shouket, Eyal Gringart, Deirdre Drake, Ulrich Steinwandel
Research outputs 2022 to 2026
Most patients with End Stage Kidney Failure (ESKF) in Pakistan must undergo maintenance haemodialysis (HD) to survive. Session duration and the often lifelong nature of this treatment, along with other factors associated with HD, make it difficult to tolerate. This study took a positive psychological perspective and considered that HD sessions’ duration, which has been a major challenge for HD patients, can be turned to an opportunity for patients’ meaningful engagement. Such meaningful engagement can positively transform Pakistani patients’ experience of HD and extend into their lives outside HD. Twenty-four HD patients and six healthcare professionals were interviewed to explore …
Flourishing In Hong Kong: An Analysis Of Wellbeing-Related Outcomes In The Global Flourishing Study, Lanxi Huang, Xu, Maggie Yue Zhao, Hanchao Hou, Aaron Jarden, Tim Lomas, Brendan Case, R. Noah Padgett, Ying Chen, Richard G. Cowden, Byron R. Johnson, Tyler J. Vanderweele
Flourishing In Hong Kong: An Analysis Of Wellbeing-Related Outcomes In The Global Flourishing Study, Lanxi Huang, Xu, Maggie Yue Zhao, Hanchao Hou, Aaron Jarden, Tim Lomas, Brendan Case, R. Noah Padgett, Ying Chen, Richard G. Cowden, Byron R. Johnson, Tyler J. Vanderweele
Research outputs 2022 to 2026
Using population-based data from Hong Kong (N = 3,012) drawn from Wave 1 of the Global Flourishing Study, this study examines the distribution of multidimensional flourishing and explores sociodemographic variation across psychological, social, physical, and economic domains. Overall, respondents reported relatively strong happiness and life satisfaction and financial wellbeing, alongside less favourable social connectedness. Patterns of flourishing varied across age, gender, education, employment, and religious affiliation, highlighting meaningful heterogeneity within the population. Early older adults tended to show more favourable wellbeing profiles, whereas younger adults and nonreligious individuals displayed comparatively lower scores across several domains. Educational attainment and employment status …
The Experience Of Homelessness Among Older Adults In Bhutan - A Narrative Inquiry Study, Phuntsho Om
The Experience Of Homelessness Among Older Adults In Bhutan - A Narrative Inquiry Study, Phuntsho Om
Theses: Doctorates and Masters
A shift in the demographics of homelessness started to occur in the 1900s, with a significant increase in the number of middle-aged or elderly men and women being recognised as a part of the homeless population. The rising urgent global concern of homelessness of older adults necessitates a deeper understanding of the lived experience and holistic well-being of these marginalised adults. This thesis aimed to explore the phenomenon of homelessness of older adults in Bhutan, which is an often neglected topic in both national and international gerontological research.
Employing narrative inquiry within the constructivist approach as articulated by Pino Gravidia …
The First Year Of Assisted Dying In New Zealand Through The Lens Of Healthcare Professionals Not Directly Involved In The Process, Waqas Arshad, Aida Dehkhoda, Melissa Carey, David B. Menkes, Nicholas Hoeh, Frederick Sundram, Rosemary Frey, Gary Cheung
The First Year Of Assisted Dying In New Zealand Through The Lens Of Healthcare Professionals Not Directly Involved In The Process, Waqas Arshad, Aida Dehkhoda, Melissa Carey, David B. Menkes, Nicholas Hoeh, Frederick Sundram, Rosemary Frey, Gary Cheung
Research outputs 2022 to 2026
Background: New Zealand’s End of Life Choice Act 2019 was enacted in 2021, allowing terminally ill people experiencing unbearable suffering to request assisted dying if they are expected to die within six months. Healthcare professionals not directly involved in assisted dying provision may have unique perspectives on implementation, yet this remains under-explored. Methods: This qualitative study was conducted between June and November 2022. We used purposive and snowball sampling to recruit potential participants through various sources, including the Ministry of Health’s assisted dying training and communication email list. A multidisciplinary research team developed a semi-structured interview guide. The individual interviews …
Postinactivity Exercise Training Improves Sarcopenia Traits In 40–60-Year-Old Women Regardless Of Fortified Milk Supplementation, Joanne Trezise, Ricardo M. Lima, Sally D. Poppitt, Aaron C. Fanning, Amanda Devine, Anthony J. Blazevich
Postinactivity Exercise Training Improves Sarcopenia Traits In 40–60-Year-Old Women Regardless Of Fortified Milk Supplementation, Joanne Trezise, Ricardo M. Lima, Sally D. Poppitt, Aaron C. Fanning, Amanda Devine, Anthony J. Blazevich
Research outputs 2022 to 2026
Background: The term sarcopenia was introduced to describe the age-related decline in muscle mass, but current definitions also include measures of muscle strength and function. Menopause increases sarcopenia risk and may exacerbate the adverse effects of physical inactivity. Exercise training is a potent stimulus to restore muscle health, and nutritional supplementation can further improve the outcomes. The purposes of this study were to examine the changes in a set of sarcopenia-related phenotypes induced by a 14-day step-reduction period followed by a 12-week exercise training programme, with or without fortified milk supplementation in healthy 40–60-year-old females, and to determine whether menopausal …
I’M Here Whether I Like It Or Not: A Focused Ethnographic Description Of Transition Into Residential Aged Care, Stacey Scott, Annette Raynor, Julie Dare, Jennifer Grieve, Leesa Costello
I’M Here Whether I Like It Or Not: A Focused Ethnographic Description Of Transition Into Residential Aged Care, Stacey Scott, Annette Raynor, Julie Dare, Jennifer Grieve, Leesa Costello
Research outputs 2022 to 2026
Transition into residential aged care (RAC) is a challenging process, often characterised by vulnerability, fear, and isolation. This study aimed to provide a contextualised description of transition within a care-facility in Australia to deepen our understanding of this major life event. A focused ethnography was conducted, which included formal interviews with residents during their first 6 months of living in RAC. The findings provide an account of the participants’ views on acceptance, highlight the challenges of loss, and showcase the coping practices new residents used. This paper provides a type of report card for the sector, which reveals that there …
Healing Right Way: A Stepped Wedge Cluster Randomised Controlled Trial Aiming To Enhance Quality Of Life For Aboriginal Australian Survivors Of Stroke And Traumatic Brain Injury, Elizabeth Armstrong, Tapan Rai, Judith M. Katzenellenbogen, Sandra J. Thompson, Meaghan Mcallister, Natalie Ciccone, Deborah Hersh, Leon Flicker, Dominique A. Cadilhac, Erin Godecke, Graeme J. Hankey, Neil Drew, Colleen Hayward, Deborah Woods, Mel Robinson, Ivan Lin, Sanita Kratina, Jane White, Juli Coffin
Healing Right Way: A Stepped Wedge Cluster Randomised Controlled Trial Aiming To Enhance Quality Of Life For Aboriginal Australian Survivors Of Stroke And Traumatic Brain Injury, Elizabeth Armstrong, Tapan Rai, Judith M. Katzenellenbogen, Sandra J. Thompson, Meaghan Mcallister, Natalie Ciccone, Deborah Hersh, Leon Flicker, Dominique A. Cadilhac, Erin Godecke, Graeme J. Hankey, Neil Drew, Colleen Hayward, Deborah Woods, Mel Robinson, Ivan Lin, Sanita Kratina, Jane White, Juli Coffin
Research outputs 2022 to 2026
Objective: To determine the effect of cultural security training (CST) for health professionals and access to an Aboriginal Brain Injury Coordinator (ABIC) for Aboriginal Australians with stroke or traumatic brain injury (TBI). Design: A stepped wedge cluster randomised controlled trial; the intervention package consisted of CST for hospital professionals and 6-month access to ABICs providing education, support, liaison and advocacy; the commencement order of the intervention phase was randomised. Setting: Four urban and four rural hospitals in Western Australia, 2018–2022. Participants: Aboriginal adults ≥ 18 years hospitalised with stroke or TBI. Main Outcome Measures: Primary outcome was quality of life …