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Annotation Of The Nuclear Receptors In An Estuarine Fish Species, Fundulus Heteroclitus, William S. Baldwin
Annotation Of The Nuclear Receptors In An Estuarine Fish Species, Fundulus Heteroclitus, William S. Baldwin
Publications
The nuclear receptors (NRs) are ligand-dependent transcription factors that respond to various internal as well as external cues such as nutrients, pheromones, and steroid hormones that play crucial roles in regulation and maintenance of homeostasis and orchestrating the physiological and stress responses of an organism. We annotated the Fundulus heteroclitus (mummichog; Atlantic killifish) nuclear receptors. Mummichog are a non-migratory, estuarine fish with a limited home range often used in environmental research as a field model for studying ecological and evolutionary responses to variable environmental conditions such as salinity, oxygen, temperature, pH, and toxic compounds because of their hardiness. F. heteroclitus …
Environmental Toxicants And Unsaturated Fatty Acids Alter Toxicant Sensitivity And Allocation Of Polar Lipids In Daphnia Magna, Namrata Sengupta
Environmental Toxicants And Unsaturated Fatty Acids Alter Toxicant Sensitivity And Allocation Of Polar Lipids In Daphnia Magna, Namrata Sengupta
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Daphnia is a commonly used test organism in toxicology, ecology, and evolution. HR96 is a CAR/PXR/VDR ortholog in invertebrates, and a promiscuous endo- and xenobiotic nuclear receptor involved in acclimation to toxicants. Daphnia HR96 is activated by chemicals such as atrazine and linoleic acid (LA) (n-6 fatty acid), and inhibited by triclosan and docosahexaenoic acid (DHA) (n-3 fatty acid). HR96 is also a key regulator of Magro, Niemann Pick genes, and other genes involved in cholesterol and triacylglycerol uptake, metabolism, and transport. We hypothesized that Daphnia magna exposed to HR96 activators will increase their lipid resources and in turn either …
Incentives And Disincentives For Day Visitors To Park And Ride Public Transportation At Acadia National Park, Frank Holly
Incentives And Disincentives For Day Visitors To Park And Ride Public Transportation At Acadia National Park, Frank Holly
All Theses
Acadia National Park, located on Maine's Mount Desert Island, attracts over 2 million visitors each year (National Park Service, 2009). To protect the park's natural resources and provide for superior visitor experiences, the National Park Service established the fare-free Island Explorer bus service in 1999 to transport visitors around the park and to surrounding destinations on Mount Desert Island. This service has seen a steady increase in annual ridership, and will further expand in the future with the completion of an off-island park-and-ride transit hub called the Acadia Gateway Center. The facility would serve as a place for day visitors …