Digital Commons Network^™

Structural Integrity, Flexibility, And Timing: Introduction To A Special Issue On Resilience, David Pincus, Adam W. Kiefer, Stephen J. Guastello

Psychology Faculty Articles and Research

This introduction to a special issue of Nonlinear Dynamics, Psychology and Life Sciences on the topic of resilience discusses the contributing articles in terms of their flexibility in methods, models, scale, and contexts combined with their integrity in shared theoretical understanding and generative knowledge. The ubiquity of resilience is discussed, a feature of potentially any living or non-living system and substance. This breadth calls for a flexible set of models and methods, along with the quest for integrative theory to make resilience science more resilient. Since resilience involves the ability of a substance or system to persist, to repair or …

Romantic Resilience: Fractal Conflict Dynamics And Network Flexibility Predict Dating Satisfaction And Commitment, David Pincus

Psychology Faculty Articles and Research

Previous research has demonstrated that interpersonal dynamics are fractal, and that conflict is a key control parameter that drives fractal complexity. The present study aimed to extend this line of research to examine the putative fractal structure of conflict dynamics over time, and the role that this self-organizing fractal structure may play in the resilience of romantic relationships. An experience sampling methodology was used to assess levels of conflict, satisfaction, and commitment in the dating relationships of undergraduate students, three times per day for 30 days. Hypothesis 1 was supported, with conflict ratings over time generally conforming to an inverse …

Hair Dye And Relaxer Use Among Cisgender Women In Embu And Nakuru Counties, Kenya: Associations With Perceived Risk Of Breast Cancer And Other Health Effects, Adana A. M. Llanos, Adiba Ashrafi, Teresa Olisa, Amber Rockson, Alexis Schaefer, Jasmine A. Mcdonald, Mary Beth Terry, Dede K. Teteh-Brooks, Dustin T. Duncan, Beatrice Irungu, Cecilia Kimani, Esther Matu

Health Sciences and Kinesiology Faculty Articles

Despite widespread use of hair products globally, little is known about the prevalence and patterns of use in populations outside the United States. As some hair products contain endocrine-disrupting chemicals (EDCs) and EDCs have been linked to breast cancer, which is increasing globally, in this study, we addressed key knowledge gaps about hair product use and practices, and perceptions of use among women in two counties in Kenya. Using community-engaged approaches in Embu and Nakuru, Kenya, we recruited women aged 15–50 years to complete a questionnaire that ascertained hair product use in the last 7–14 days, ever using hair dyes …

Uniting For Impact: A Journey Of Partnerships - Chapman University Case Study, Essraa Nawar, Taylor Greene

Library Articles and Research

This presentation highlights a decade-long collaboration between the Assistant Dean for Development and the Performing Arts Librarian at Chapman University's Leatherby Libraries, resulting in over $3 million in transformative contributions. Central to their success is the acquisition of the Henri Temianka Archives, a treasure trove of 20th-century classical music history. Through strategic stewardship, they secured this significant gift, enhancing research and cultural exchange. Additional achievements include the Ronald B. Broadwell Antique Musical Instruments collection, a Legacy gift, and an Endowed Fund for Music Collections. This partnership exemplifies the strategic impact of librarian-fundraiser collaborations, bridging divides and yielding enduring benefits for …

Assessment And Prediction Of Meteorological Drought Using Machine Learning Algorithms And Climate Data, Khalid En-Nagre, Mourad Aqnouy, Ayoub Ouarka, Syed Ali Asad Naqvi, Ismail Bouizrou, Jamal Eddine Stitou El Messari, Aqil Tariq, Walid Soufan, Wenzhao Li, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

Monitoring drought in semi-arid regions due to climate change is of paramount importance. This study, conducted in Morocco’s Upper Drâa Basin (UDB), analyzed data spanning from 1980 to 2019, focusing on the calculation of drought indices, specifically the Standardized Precipitation Index (SPI) and the Standardized Precipitation Evapotranspiration Index (SPEI) at multiple timescales (1, 3, 9, 12 months). Trends were assessed using statistical methods such as the Mann-Kendall test and the Sen’s Slope estimator. Four significant machine learning (ML) algorithms, including Random Forest, Voting Regressor, AdaBoost Regressor, and K-Nearest Neighbors Regressor, were evaluated to predict the SPEI values for both three …

Who Helps Tsimane Children And Adults?, Eric Schniter, Daniel K. Cummings, Paul L. Hooper, Jonathan Stieglitz, Benjamin C. Trumble, Hillard S. Kaplan, Michael D. Gurven

ESI Working Papers

We examine various forms of helping behavior among Tsimane Amerindians of Bolivia, focusing on the provision of shelter, childcare, food, sickcare, cultural influence, and traditional story knowledge. Kin selection theory traditionally explains nepotistic nurturing of youth by closely related kin. However, less attention has been given to understanding the help provided by individuals without close genetic relatedness. To explain who provides various forms of help, we evaluate support for several predictions derived from kin selection theory. Our results show that helpers who are most often closely related and from an older generation tend to provide more costly forms of help …

Do You Say Please Or Thank You To Chatgpt? The Subtle Influence Of Prompt Engineering On Digital Civility, Essraa Nawar

Library Articles and Research

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In the dynamic and rapidly evolving landscape of artificial intelligence, tools like ChatGPT have become integral to our daily digital interactions. These advanced AI systems assist us with a myriad of tasks, from generating text and answering complex questions to providing creative solutions. However, as we engage more frequently with these non-human entities, an intriguing question arises: Are we inadvertently becoming ruder in our digital communications, or are we consciously maintaining our ingrained habits of politeness?"

Antidepressant Effect Of Enzymatic Porcine Placenta Hydrolysate In Repeated Immobilization Stress-Induced Ovariectomized Female Mice, Minsook Ye, Sharon Nguyen, Min Ju Kim, Jee Sun Hwang, Gun Won Bae, Keun-Hang Susan Yang, Insop Shim

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

When postmenopausal women are under stress conditions, this exacerbates mood disorders and issues with neuroimmune systems. The porcine placenta is known to relieve menopausal depression in clinical trials, but its underlying mechanisms for depression and anti-inflammatory functions remain poorly defined. The present study was designed to examine the anti-inflammatory effects of enzymatic porcine placenta hydrolysate (EPPH) on LPS-induced levels of nitric oxide (NO), prostaglandin E2 (PGE2), corticosterone (CORT), and pro-inflammatory cytokine interleukin-1 beta (IL-1β) in RAW 264.7 macrophage cells. In addition, the neurite outgrowth of PC12 cells was evaluated to examine the effects of EPPH on neurite growth. To mimic …

Mean Affect Moderates The Association Between Affect Variability And Mental Health, Brooke N. Jenkins, Lydia Q. Ong, Anthony D. Ong, Hee Youn (Helen) Lee, Julia K. Boehm

Psychology Faculty Articles and Research

Increasing evidence suggests that within-person variation in affect is a dimension distinct from mean levels along which individuals can be characterized. This study investigated affect variability’s association with concurrent and longitudinal mental health and how mean affect levels moderate these associations. The mental health outcomes of depression, panic disorder, self-rated mental health, and mental health professional visits from the second and third waves of the Midlife in the United States Study were used for cross-sectional (n = 1,676) and longitudinal outcomes (n = 1,271), respectively. These participants took part in the National Study of Daily Experiences (NSDE II), …

A Single-Center, Assessor-Blinded, Randomized Controlled Clinical Trial To Test The Safety And Efficacy Of A Novel Brain-Computer Interface Controlled Functional Electrical Stimulation (Bci-Fes) Intervention For Gait Rehabilitation In The Chronic Stroke Population, Piyashi Biswas, Lucy Dodakian, Po T. Wang, Christopher A. Johnson, Jill See, Vicky Chan, Cathy Chou, Wendy Lazouras, Alison L. Mckenzie, David J. Reinkensmeyer, Danh V. Nguyen, Steven C. Cramer, An H. Do, Zoran Nenadic

Physical Therapy Faculty Articles and Research

Background

In the United States, there are over seven million stroke survivors, with many facing gait impairments due to foot drop. This restricts their community ambulation and hinders functional independence, leading to several long-term health complications. Despite the best available physical therapy, gait function is incompletely recovered, and this occurs mainly during the acute phase post-stroke. Therapeutic options are limited currently. Novel therapies based on neurobiological principles have the potential to lead to long-term functional improvements. The Brain-Computer Interface (BCI) controlled Functional Electrical Stimulation (FES) system is one such strategy. It is based on Hebbian principles and has shown promise …

Mechanistic Study Of Antimicrobial Effectiveness Of Cyclic Amphipathic Peptide [R4W4] Against Methicillin-Resistant Staphylococcus Aureus Clinical Isolates, Ajayi David Akinwale, Keykavous Parang, Rakesh Kumar Tiwari, Jason Yamaki

Pharmacy Faculty Articles and Research

Antimicrobial peptides (AMPs) are being explored as a potential strategy to combat antibiotic resistance due to their ability to reduce susceptibility to antibiotics. This study explored whether the [R₄W₄] peptide mode of action is bacteriostatic or bactericidal using modified two-fold serial dilution and evaluating the synergism between gentamicin and [R₄W₄] against Escherichia coli (E. coli) and methicillin-resistant Staphylococcus aureus (MRSA) by a checkered board assay. [R₄W₄] exhibited bactericidal activity against bacterial isolates (MBC/MIC ≤ 4), with a synergistic effect with gentamicin against E. coli (FICI = 0.3) but …

“I Tell Them Generics, But Not The Specifics”: Exploring Tensions Underlying Familial Support For First-Generation Latinx Undergraduate Students, Stephany Cuevas

Education Faculty Articles and Research

Families continue to play an essential role in the experiences of first-generation Latinx undergraduate students and can serve as powerful partners to support student retention and socioemotional wellbeing. This qualitative phenomenological study uses the notion of emerging adulthood to explore how first-generation Latinx undergraduate students (n = 16) conceptualize their families’ role in their college education. Specifically, this study shows that while students describe feeling supported by their families, they also experience distinct and unique tensions tied to this support, which students associate with their first-generation student status. These tensions include (1) the family’s unfamiliarity with college culture; (2) bidirectional …

Mechanistic Insight Into The Mode Of Inhibition Of Dietary Flavonoids; Targeting Macrophage Migration Inhibitory Factor, Ali Raza Siddiqui, Mamona Mushtaq, Madiha Sardar, Lubna Atta, Mohammad Nur-E-Alam, Aftab Ahmad, Zaheer Ul-Haq

Pharmacy Faculty Articles and Research

Introduction: The Macrophage Migration Inhibitory Factor (MIF), a key pro-inflammatory mediator, is responsible for modulating immune responses. An array of inflammatory and autoimmune diseases has been linked to the dysregulated activity of MIF. The significance in physiological as well as pathophysiological phenomena underscores the potential of MIF as an attractive target with pharmacological relevance. Extensive research in past has uncovered a number of inhibitors, while the ISO-1, or (S, R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester being recognized as a benchmark standard so far. Recent work by Yang and coworkers identified five promising dietary flavonoids, with superior activity compared to the standard …

Inverse-Designed Integrated Biosensors, Azadeh Didari-Bader, Sophie Pelton, Nasim Mohammadi Estrakhri

Engineering Faculty Articles and Research

We propose a refractive index sensor in a silicon-on-insulator (SOI) platform inspired by the operation of multimode fiber sensors. The sensor utilizes an optimized SOI resonator through adjoint-based inverse design topology optimization. The device’s refractive index distribution is calculated with a suitable figure of merit tailored for telecommunication band operation (1450 nm to 1650 nm) and is compatible with the standard fabrication processes. The flexibility of design offered through topology optimization and the localized interactions of the wave around the metastructure can be tailored to achieve maximum sensitivity. Our results may find interesting applications in wearable technologies, biosensing, and environmental …

“Women And Lockean Theory: John Locke, Rachel Speght, And Egalitarian Personhood, Katherine Gillespie, Bas Van Der Vossen

Philosophy Faculty Articles and Research

Liberal political thought affirms the moral equality of all persons. The Lockean tradition within liberalism captures this equality by endowing people with equal natural rights. However, a powerful line of criticism holds that the theory fails to live up to its egalitarian billing by treating men and women differently. This article offers a rational reconstruction of the Lockean position on gender equality, and the rights of women in particular. We propose a novel interpretative method which puts Locke into conversation with a contemporary female author, Rachel Speght. In Speght, we find an interesting argument supporting an egalitarian Lockean view, grounded …

Pediatric Obesity In The United States: Age–Period–Cohort Analysis, Ashley W. Kranjac, Dinko Kranjac, Roxanne I. Aguilera

Sociology Faculty Articles and Research

The rates of obesity among American children aged 2–5 years has reached a historic high. It is crucial to identify the putative sources of population-level increases in obesity prevalence among preschool-aged children because early childhood is a critical window for obesity prevention and thus reduction of future incidence. We used the National Health and Nutrition Examination Survey data and hierarchical age–period–cohort analysis to examine lifecycle (i.e., age), historical (i.e., period), and generational (i.e., cohort) distribution of age- and sex-specific body mass index z-scores (zBMI) among 2–5-year-olds in the U.S. from 1999 to 2018. Our current findings indicate that period effects, …

On The Impact Of Geospace Weather On The Occurrence Of M7.8/M7.5 Earthquakes On 6 February 2023 (Turkey), Possibly Associated With The Geomagnetic Storm Of 7 November 2022, Dimitar Ouzounov, Galina Khachikyan

Mathematics, Physics, and Computer Science Faculty Articles and Research

A joint analysis of solar wind, geomagnetic field, and earthquake catalog data showed that before the catastrophic M = 7.8 and M = 7.5 Kahramanmaras earthquake sequence on 6 February 2023, a closed strong magnetic storm occurred on 7 November 2022, SYM/H = −117 nT. The storm started at 08:04 UT. At this time, the high-latitudinal part of Turkey’s longitudinal region of future epicenters was located under the polar cusp, where the solar wind plasma would directly access the Earth’s environment. The time delay between storm onset and earthquake occurrence was ~91 days. We analyzed all seven strong (M7+) earthquakes …

The Future Of Intergenerational Transmission Research: A Prospective, Three-Generation Approach, Mariann A. Howland, Laura M. Glynn

Psychology Faculty Articles and Research

Dr. Dante Cicchetti’s pioneering theory and research on developmental psychopathology have been fundamental to the proliferation of research on intergenerational transmission over the last 40 years. In part due to this foundation, much has been learned about continuities and discontinuities in child maltreatment, attachment, parenting, and psychopathology across generations. Looking towards the future, we propose that this field stands to benefit from a prospective, three-generation approach. Specifically, following established prospective, longitudinal cohorts of children over their transition to parenting the next generation will afford the opportunity to investigate the developmental origins of intergenerational transmission. This approach also can address key …

Effectiveness Of Empiric Carbapenem Versus Non-Carbapenem Therapy For Extended-Spectrum Β-Lactamase Producing Enterobacterales Infections In Non-Intensive Care Unit Patients: A Real-World Investigation In A Hospital With High-Prevalence Of Extended-Spectrum Β-Lactamase Producing Enterobacterales, Amy Y. Kang, Mary Elkomos, Danny Pham, Michelle Guerrero, Deborah Kupferwasser, Loren G. Miller

Pharmacy Faculty Articles and Research

Objective:

To investigate whether empiric carbapenem therapy, compared to empiric non-carbapenem therapy, was associated with improved clinical outcomes among hospitalized, non-intensive care unit (ICU) patients with extended-spectrum β-lactamase (ESBL)-producing Enterobacterales infections.

Methods:

We performed a retrospective cohort study of adult, non-ICU patients admitted with ESBL-producing Enterobacterales infections. Primary outcome was time to clinical stability from the first empiric antibiotic dose. Secondary outcomes were early clinical response and 30-day all-cause hospital readmission. We used multivariate regression methods to examine time to clinical stability.

Results:

Of the 142 patients, 59 (42%) received empiric carbapenems and 83 (58%) received empiric …

Evaluating Visual Dependence In Postural Stability Using Smartphone And Stroboscopic Glasses, Brent A. Harper, Michael Shiraishi, Rahul Soangra

Physical Therapy Faculty Articles and Research

This study explores the efficacy of integrating stroboscopic glasses with smartphone-based applications to evaluate postural control, offering a cost-effective alternative to traditional forceplate technology. Athletes, particularly those with visual and visuo-oculomotor enhancements due to sports, often suffer from injuries that necessitate reliance on visual inputs for balance—conditions that can be simulated and studied using visual perturbation methods such as stroboscopic glasses. These glasses intermittently occlude vision, mimicking visual impairments that are crucial in assessing dependency on visual information for postural stability. Participants performed these tasks under three visual conditions: full vision, partial vision occlusion via stroboscopic glasses, and no vision …

Moral Content Diminishes Preference Falsification, Maxine Bonneau, Tanya O'Garra, Praveen Kujal

ESI Working Papers

We examine how the moral (or neutral) content of an issue influences the tendency to falsify attitudes, given varying social and monetary incentives to engage in such ‘preference falsification’. We conduct an incentivized two stage online experimental study where, in a prior first stage, attitude strength over moral and neutral issues is elicited. Then, in the second stage participants in groups of ten were asked to express their preferences regarding the moral or neutral issues for each possible combination of supporters and opposers in their group, each associated with varying monetary payoffs. More than half of the participants falsify their …

Ideology And Economic Change, Jared Rubin, Debin Ma

ESI Working Papers

This paper revisits the old theses of the contrasting paths to modernization between Japan and China. It develops a new analytical framework regarding the role of ideology and ideological change—Meiji Japan’s decisive turn towards the West pitted against Qing China’s lethargic response to Western imperialism—as the key driver behind these contrasting paths. Our framework and historical narrative highlight the contrast between Tokugawa Japan’s feudal, decentralized political regime and Qing China’s centralized bureaucratic system as a key determinant driving the differential patterns of ideological realignment. We argue that the 1894-95 Japanese naval victory over China could not be justified under the …

Individual Longitudinal Changes In Dna-Methylome Identify Signatures Of Early-Life Adversity And Correlate With Later Outcome, Annabel K. Short, Ryan Weber, Noriko Kamei, Christina Wilcox Thai, Hina Arora, Ali Mortazavi, Hal S. Stern, Laura M. Glynn, Tallie Z. Baram

Psychology Faculty Articles and Research

Adverse early-life experiences (ELA) affect a majority of the world's children. Whereas the enduring impact of ELA on cognitive and emotional health is established, there are no tools to predict vulnerability to ELA consequences in an individual child. Epigenetic markers including peripheral-cell DNA-methylation profiles may encode ELA and provide predictive outcome markers, yet the interindividual variance of the human genome and rapid changes in DNA methylation in childhood pose significant challenges. Hoping to mitigate these challenges we examined the relation of several ELA dimensions to DNA methylation changes and outcome using a within-subject longitudinal design and a high methylation-change threshold. …

Detecting Drifts In Data Streams Using Kullback-Leibler (Kl) Divergence Measure For Data Engineering Applications, Jeomoan Francis Kurian, Mohamed Allali

Engineering Faculty Articles and Research

The exponential growth of data coupled with the widespread application of artificial intelligence(AI) presents organizations with challenges in upholding data accuracy, especially within data engineering functions. While the Extraction, Transformation, and Loading process addresses error-free data ingestion, validating the content within data streams remains a challenge. Prompt detection and remediation of data issues are crucial, especially in automated analytical environments driven by AI. To address these issues, this study focuses on detecting drifts in data distributions and divergence within data fields processed from different sample populations. Using a hypothetical banking scenario, we illustrate the impact of data drift on automated …

Perceptions Of Metabolic Syndrome Management Utilization In Relation To Patient Experience And Health-Related Quality Of Life, Olajide Adekunle, Jon C. Schommer, Yun Wang, Ismaeel Yunusa, Marc L. Fleming, Enrique Seoane-Vazquez, Lawrence M. Brown

Pharmacy Faculty Articles and Research

Background

One factor for the poor health outcomes among adult people with metabolic syndrome (MetS) is poor utilization of disease management resources, which may be attributable to prior experience with pharmacists (PEwP) and perceptions of disease management resource utilization (PMU). Therefore, understanding patients' experience could be critical to improving their perceptions and promoting health outcomes.

Objectives

The study explored the influence of PEwP and PMU on the health-related quality of life (HRQoL) of people with MetS.

Methods

Data on perceptions of healthcare, medication, and pharmacy services utilization, PEwP, and HRQoL were collected using validated tools via an electronic survey. Chi-square …

Combined Use Of Donepezil And Memantine Increases The Probability Of Five-Year Survival Of Alzheimer’S Disease Patients, Ehsan Yaghmaei, Hongxia Lu, Louis Ehwerhemuepha, Jianwei Zheng, Sidy Danioko, Ahmad Rezaie, Seyed Ahmad Sajjadi, Cyril Rakovski

Mathematics, Physics, and Computer Science Faculty Articles and Research

Background

Alzheimer’s disease (AD) is the most common neurodegenerative disease. Studying the effects of drug treatments on multiple health outcomes related to AD could be beneficial in demonstrating which drugs reduce the disease burden and increase survival.

Methods

We conducted a comprehensive causal inference study implementing doubly robust estimators and using one of the largest high-quality medical databases, the Oracle Electronic Health Records (EHR) Real-World Data. Our work was focused on the estimation of the effects of the two common Alzheimer’s disease drugs, Donepezil and Memantine, and their combined use on the five-year survival since initial diagnosis of AD patients. …

Influences Of Cultural Capital And Internationalization On Global Competence In Higher Education: A Systematic Literature Review, Yiying Teng, Meghan E. Cosier

Education Faculty Articles and Research

Introduction: In an increasingly global economy, the global competence of students in higher education is a critical area of importance. The purpose of the study was to explore the research on factors that influence an individual’s global competence in both international and Chinese contexts.

Methods: Under the umbrella of cultural capital theory and Internationalization, a systematic literature review analyzed and synthesized the empirical studies of global competence from 2013 to 2022.

Results: This research revealed that students with higher cultural capital backgrounds obtain more educational opportunities and further exhibit better global competence achievement. Internationalization abroad is a direct and practical …

Bikeability Disparities In Orange County, California: Intersection Of Place And Demographics, Jeanette Gritton, Maria Cristina Martinez, Georgiana Bostean, Megan Thiele Strong

Sociology Faculty Articles and Research

Active transportation modes such as walking and biking are gaining popularity for their extensive health and environmental benefits, yet scholars know little about how place-based accessibility varies by area sociodemographic composition. This study is among the first to examine sociodemographic disparities (by both race and socioeconomic status) in bikeability while allowing for heterogeneity in disparities. Consideration of bikeability disparities is particularly critical within the framework of urban planning concepts that promote equitable accessibility and reduced dependency on automobiles, such as the 15-minute city. Geographically Weighted Regressions examined associations between census tract-level bikeability (using an index that combines five components), socioeconomic …

Proteomic Characterization And Cytotoxic Potential Of Proteins From Cuscuta (Cuscuta Epithymum (L.) Crude Herbal Product Against Mcf-7 Human Breast Cancer Cell Line, Umaima Akhtar, Yamna Khurshid, Bishoy El-Aarag, Basir Syed, Ishtiaq A. Khan, Keykavous Parang, Aftab Ahmed

Pharmacy Faculty Articles and Research

Background

The burden of breast cancer, the second leading cause of death worldwide, is increasing at an alarming rate. Cuscuta, used in traditional medicine for different ailments, including cancer, is known for containing phytochemicals that exhibit anticancer activity; however, the bioactivities of proteins from this plant remain unexplored. This study aimed to screen the cytotoxic potential of proteins from the crude herbal product of Cuscuta epithymum(L.) (CE) harvested from the host plants Alhagi maurorum and Medicago sativa.

Methods

The proteins from CE were extracted using a salting-out method, followed by fractionation with a gel filtration chromatography column. Gel-free shotgun …

Highlighting Health And Diversity: Curating Digital Exhibits To Promote Online Resources Across Cultural Months, Ivan Portillo, David Carson

Library Presentations, Posters, and Audiovisual Materials

This poster presentation demonstrates how digital exhibits can be leveraged to promote health literacy and enhance health education by creating awareness of resources to benefit diverse cultural and ethnic groups. It showcases examples of online exhibits that highlight health-related information, history, and resources to address health disparities and promote health equity among different populations.