Digital Commons Network^™

Nicotine-Induced Effects On Nicotinic Acetylcholine Receptors (Nachrs), Ca2+ And Brain-Derived Neurotrophic Factor (Bdnf) In Stc-1 Cells, Jie Qian, Shobha K. Mummalaneni, Reem M. Alkahtan, Sunila Mahavadi, Karnam S. Murthy, John R. Grider, Vijay Lyall

Physiology and Biophysics Publications

In addition to the T2R bitter taste receptors, neuronal nicotinic acetylcholine receptors (nAChRs) have recently been shown to be involved in the bitter taste transduction of nicotine, acetylcholine and ethanol. However, at present it is not clear if nAChRs are expressed in enteroendocrine cells other than beta cells of the pancreas and enterochromaffin cells, and if they play a role in the synthesis and release of neurohumoral peptides. Accordingly, we investigated the expression and functional role of nAChRs in enteroendocrine STC-1 cells. Our studies using RT-PCR, qRT-PCR, immunohistochemical and Western blotting techniques demonstrate that STC-1 cells express several α and …

Participation And The Poor: Social Accountability Institutions And Poverty Reduction In Brazil, Michael Touchton, Brian Wampler, Natasha Borges Sugiyama

Political Science Faculty Publications and Presentations

Democracy, according to a large body of research, contributes to human development by improving citizens' lives (Prezeworkski et al. 2000; Gerrign et al. 2012; McGuire 2010; Baum and Lake 2003; Gerring et al. 2015). Broad evidence demonstrates that democracies provide higher standards of living, on average, for their citizens than authoritarian countries (Boix 2001; Brown and Hunter 2004; Brown and Mobarak 2009; Besley and Kudamatsu 2006; Lake and Baum 2001). But what is it about democratic practice that enhances the quality of its citizens' lives? Proponents argue that democratic practices such as competitive elections, checks and balances, and protection of …

Rapamycin Rescues Vascular, Metabolic And Learning Deficits In Apolipoprotein E4 Transgenic Mice With Pre-Symptomatic Alzheimer’S Disease, Ai-Ling Lin, Jordan B. Jahrling, Wei Zhang, Nicholas Derosa, Vikas Bakshi, Peter Romero, Veronica Galvan, Arlan Richardson

Sanders-Brown Center on Aging Faculty Publications

Apolipoprotein E ɛ4 allele is a common susceptibility gene for late-onset Alzheimer's disease. Brain vascular and metabolic deficits can occur in cognitively normal apolipoprotein E ɛ4 carriers decades before the onset of Alzheimer's disease. The goal of this study was to determine whether early intervention using rapamycin could restore neurovascular and neurometabolic functions, and thus impede pathological progression of Alzheimer's disease-like symptoms in pre-symptomatic Apolipoprotein E ɛ4 transgenic mice. Using in vivo, multimodal neuroimaging, we found that apolipoprotein E ɛ4 mice treated with rapamycin had restored cerebral blood flow, blood–brain barrier integrity and glucose metabolism, compared …

The Murray Ledger And Times, December 31, 2015, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

2015 Final Report: Status Of The Arizona Toad (Anaxyrus Microscaphus) In New Mexico, Mason J. Ryan, Ian M. Latella, Jacek Tomasz Giermakowski, Howard L. Snell

Biology Faculty & Staff Publications

In 2013, we initiated a field study to assess the status of the Arizona Toad (Anaxyrus microscaphus) in New Mexico. Herein we provide the results of three years (2013-2015) of range-wide population monitoring, a review of threat assessments, and several contributions to the basic ecology of the Arizona Toad in New Mexico. This work highlights the sensitivity of the species to abiotic factors and emphasizes the nature of annual population fluctuations in a variable environment. We provide analyses of environmental factors that influence toad reproductive behaviors, employ occupancy and detection modeling at breeding sites, and provide analyses of tadpole habitat …

Association Of State Wetland Managers 2015 Annual Report, Association Of State Wetland Managers

Documents from Environmental Organizations

No abstract provided.

Effects Of Whole Body Vibration Training On Body Composition, Skeletal Muscle Strength, And Cardiovascular Health, Song-Young Park, Won-Mok Son, Oh-Sung Kwon

Health and Kinesiology Faculty Publications

Whole body vibration training (WBVT) has been used as a supplement to conventional exercise training such as resistance exercise training to improve skeletal muscle strength, specifically, in rehabilitation field. Recently, this exercise modality has been utilized by cardiovascular studies to examine whether WBVT can be a useful exercise modality to improve cardiovascular health. These studies reported that WBVT has not only beneficial effects on muscular strength but also cardiovascular health in elderly and disease population. However, its mechanism underlying the beneficial effects of WBVT in cardiovascular health has not been well documented. Therefore, this review highlighted the impacts of WBVT …

Selection Signatures In Four Lignin Genes From Switchgrass Populations Divergently Selected For In Vitro Dry Matter Digestibility, Shiyu Chen, Shawn M. Kaeppler, Kenneth P. Vogel, Michael D. Casler

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Switchgrass is undergoing development as a dedicated cellulosic bioenergy crop. Fermentation of lignocellulosic biomass to ethanol in a bioenergy system or to volatile fatty acids in a livestock production system is strongly and negatively influenced by lignification of cell walls. This study detects specific loci that exhibit selection signatures across switchgrass breeding populations that differ in in vitro dry matter digestibility (IVDMD), ethanol yield, and lignin concentration. Allele frequency changes in candidate genes were used to detect loci under selection. Out of the 183 polymorphisms identified in the four candidate genes, twenty-five loci in the intron regions and four loci …

State Of Utah, Appellant, V. Manual Antonio Lujan, Appellee, Utah Supreme Court

Utah Supreme Court Briefs (2000– )

Brief of Respondent on Certiorari Review

State Of Utah, Plaintiff/Petitioner, V. Manuel Antonio Lujan, Defendant/Respondent, Utah Supreme Court

Utah Supreme Court Briefs (2000– )

On Writ of Certiorari to the Utah Court of Appeals

Utah Stream Access Coalition, A Utah Non-Profit Corporation, Plaintiff/Appellee, Vs. Vr Acquisitions Llc, A Delaware Limited Liability Company, Et Al., Defendants/Appellants, Utah Supreme Court

Utah Supreme Court Briefs (2000– )

Appeal from the Fourth Judicial District Court, Wasatch County, Honorable Derek Pullan, Judge Case #100500558

Arkansas Water Resources Center Annual Technical Report, 2015, Arkansas Water Resources Center

Arkansas Water Resources Center Annual Report

No abstract provided.

Annual Report, 2015, University Of Arkansas, Fayetteville. Graduate School And International Education

Graduate School and International Education Annual Report

No abstract provided.

Scholarworks Statistics - January Through December 2015, Scholarworks

ScholarWorks Reports

During 2015, ScholarWorks recorded a total of 339,066 full-text and additional file downloads and 144,173 page views.

Resist Newsletter, Winter 2015, Resist

Resist Newsletters

No abstract provided.

Permanent Draft Genome Sequence Of Frankia Sp. Strain Avci1, A Nitrogen-Fixing Actinobacterium Isolated From The Root Nodules Of Alnus Viridis Subsp. Crispa Grown In Canada, Erik Swanson, Rediet Oshone, Stephen Simpson, Krystalynne Morris, Feseha Abebe-Akele, W. Kelley Thomas, Louis S. Tisa

Molecular, Cellular & Biomedical Sciences

Frankia strain AvcI1, isolated from root nodules of Alnus viridis subsp. crispa, is a member of Frankia lineage Ia, which is able to reinfect plants of the Betulaceae and Myricaceae families. Here, we report a 7.7-Mbp draft genome sequence with a G+C content of 72.41% and 6,470 candidate protein-encoding genes.

Permanent Draft Genome Sequence Of Frankia Sp. Strain Avci1, A Nitrogen-Fixing Actinobacterium Isolated From The Root Nodules Of Alnus Viridis Subsp. Crispa Grown In Canada, Erik Swanson, Rediet Oshone, Stephen D. Simpson, Krystalynne Morris, Feseha Abebe-Akele, William Kelley Thomas, Louis S. Tisa

New Hampshire Agricultural Experiment Station Publications

Frankia strain AvcI1, isolated from root nodules of Alnus viridis subsp. crispa, is a member of Frankia lineage Ia, which is able to reinfect plants of the Betulaceae and Myricaceae families. Here, we report a 7.7-Mbp draft genome sequence with a G+C content of 72.41% and 6,470 candidate protein-encoding genes.

Admissions Report - Detailed Data - December 2015, Office Of Institutional Research & Effectiveness, Wright State University

Admissions Reports

Detailed report of applicants to Wright State including data on county of residency, intended major, and ethnicity for Fall Semester 2015.

Admissions Report - Summary Data - December 2015, Office Of Institutional Research & Effectiveness, Wright State University

Admissions Reports

Summary report of applicants to Wright State including data on ethnicity, region, intended college, transfer, and direct admit from high school for Fall Semester 2016.

2015 Q4 Market Pulse Report, Craig R. Everett

Pepperdine Market Pulse Report

The quarterly IBBA and M&A Source Market Pulse Survey was created to gain an accurate understanding of the market conditions for businesses being sold in Main Street (values $0-$2MM) and the lower middle market (values $2MM -$50MM). The national survey was conducted with the intent of providing a valuable resource to business owners and their advisors. The IBBA and M&A Source present the Market Pulse Survey with the support of the Pepperdine Private Capital Markets Project and the Graziado School of Business and Management at Pepperdine University.

Touch Dna In A Complicated Alleged Child Abuse Case, Heather Miller Coyle

Forensic Science Publications

Touch DNA can be of use in establishing what may have occurred through reconstruction of events based on biological evidence transfer. However, interpretation of results and patterns must be approached with some caution as in the alleged child abuse case detailed here. This case was brought forward as a touch DNA and body fluid case where the male in question was a father reported to have forced a young child to perform oral sex on him. Her pajamas were collected and evaluated for presence of body fluids and associated DNA. The sleeves of the pajamas tested positive for amylase, a …

Concussion The Film, Richard C. Crepeau

On Sport and Society

Several months ago there was a minor flap over the fact that the National Football League was given the right to delete parts of the film “Concussion” before its general release to the public. At the time many, including myself, feared that the NFL would defang the bite of the film. It did not. In fact it’s hard to imagine what the NFL censored in “Concussion” given the devastating nature of the final product which is now in release.

Geoffrey S. Rule, Petitioner/Appellee, -Vs- Richelle Rule, Respondent/Appellant. : Brief Of Appellee, Utah Court Of Appeals

Utah Court of Appeals Briefs (2007– )

BRIEF OF APPELLEE

THIS APPEAL IS FROM THE JUDGMENT AND ORDER OF THE
HONORABLE SU CHON, THIRD DISTRICT COURT, SALT LAKE
COUNTY, STATE OF UTAH.

State Of Utah, Plaintiff/Petitioner, V. Manuel Antonio Lujan, Defendant/Respondent, Utah Supreme Court

Utah Supreme Court Briefs (2000– )

On Writ of Certiorari to the Utah Court of Appeals

Sofosbuvir And Velpatasvir For Hcv Genotype 2 And 3 Infection, Graham R. Foster, Nezam Afdhal, Stuart K. Roberts, Norbert Bräu, Edward J. Gane, Stephen Pianko, Eric Lawitz, Alex Thompson, Mitchell L. Shiffman, Curtis Cooper, William J. Towner, Brian Conway, Peter Ruane, Marc Bourlière, Tarik Asselah, Thomas Berg, Stefan Zeuzem, William Rosenberg, Kosh Agarwal, Catherine Am Stedman, Hongmei Mo, Hadas Dvory-Sobol, Lingling Han, Jing Wang, John Mcnally, Anu Osinusi, Diana M. Brainard, John G. Mchutchison, Francesco Mazzotta, Tram T. Tran, Stuart C. Gordon, Keyur Patel, Nancy Reau, Alessandra Mangia, Mark Sulkowski

Gastroenterology Articles

BACKGROUND: In phase 2 trials, treatment with the combination of the nucleotide polymerase inhibitor sofosbuvir and the NS5A inhibitor velpatasvir resulted in high rates of sustained virologic response in patients chronically infected with hepatitis C virus (HCV) genotype 2 or 3.

METHODS: We conducted two randomized, phase 3, open-label studies involving patients who had received previous treatment for HCV genotype 2 or 3 and those who had not received such treatment, including patients with compensated cirrhosis. In one trial, patients with HCV genotype 2 were randomly assigned in a 1:1 ratio to receive sofosbuvir-velpatasvir, in a once-daily, fixed-dose combination tablet …

St. Francis Of Assisi Catholic Church And Center For The Deaf Sunday Bulletin, December 31, 2015

Saint Francis of Assisi Catholic Church and Center for the Deaf Sunday Bulletin

A newsletter published for Deaf Catholics in Landover Hills, MD

St. Francis of Assisi Catholic Church and Center for the Deaf Sunday Bulletin Finding Aid

Report To The Maine Legislature Joint Standing Committee On Education And Cultural Affairs, 2015, University Of Maine System

General University of Maine Publications

The University of Maine System remediation report to the Legislature

University Of Maine System - Remediation Report 2015, University Of Maine System

General University of Maine Publications

The report includes the number of Maine high school students who matriculated at one of the University of Maine System institutions directly out of high school and who required enrollment in one or more remedial/developmental courses.

Lineage-Specific Methyltransferases Define The Methylome Of The Globally Disseminated Escherichia Coli St131 Clone, Brian M. Forde, Minh Duy Phan, Jayde A. Gawthorne, Melinda M. Ashcroft, Mitchell Stanton-Cook, Sohinee Sarkar, Kate M. Peters, Kok Gan Chan, Teik Min Chong, Wai Fong Yin, Mathew Upton, Mark A. Schembri, Scott A. Beatson

School of Biomedical Sciences

ABSTRACT Escherichia coli sequence type 131 (ST131) is a clone of uropathogenic E. coli that has emerged rapidly and disseminated globally in both clinical and community settings. Members of the ST131 lineage from across the globe have been comprehensively characterized in terms of antibiotic resistance, virulence potential, and pathogenicity, but to date nothing is known about the methylome of these important human pathogens. Here we used single-molecule real-time (SMRT) PacBio sequencing to determine the methylome of E. coli EC958, the most-well-characterized completely sequenced ST131 strain. Our analysis of 52,081 methylated adenines in the genome of EC958 discovered three m6 A …

Playing Tetris Decreases Drug And Other Cravings In Real World Settings, J Skorka-Brown, J Andrade, B Whalley, J May

School of Psychology

Most research on cognitive processes in craving has been carried out in the laboratory and focuses on food craving. This study extends laboratory findings to real world settings and cravings for drugs or activities as well as food. Previous laboratory research has found that playing Tetris reduces craving strength. The present study used an ecological momentary assessment protocol in which 31 undergraduate participants carried iPods for a week and were prompted 7 times each day, by SMS message, to use their iPod to report craving. Participants reported craving target and strength (0- 100), whether they indulged their previous craving (yes/no), …