Digital Commons Network^™

Progressive Neurochemical, Neuroinflammatory And Cognitive Deficits In An Experimental Model Of Gulf War Illness, Hannah Elizabeth Burzynski

Theses and Dissertations

Gulf War Illness (GWI) is a multi-symptom illness that presents with cognitive disturbances and immune dysregulation and continues to affect over 25% of Gulf War veterans. While soldiers were exposed to several hazards in the Gulf, the prophylactic use of the acetylcholinesterase inhibitor, pyridostigmine bromide (PB) and war-related stress have been identified as chief factors in GWI pathology. As both PB and stress alter acetylcholine (ACh), a critical mediator of cognition and inflammation, the focus of my dissertation work was investigating the lasting effects of PB and stress on peripheral and central cholinergic signaling. Specifically, I assessed hippocampal-dependent learning and …

No More Loosies: A Mixed-Methods Study On The Implementation And Enforcement Of The Loose Cigarette And Bidi Sale Ban In India, Mayank Sakhuja

Theses and Dissertations

Background: Sale of loose cigarettes and bidis (loosies) is widely accepted as a key factor in promoting the tobacco epidemic in India. This mixed-methods study aimed to broaden understanding around the sale and purchase of loosies addressed three aims: 1) To determine the prevalence and correlates of loosies purchase in India; 2) To examine the association between purchase behavior and health warning labels (HWLs) exposure and responses, and 3) To conduct a stakeholder analysis regarding the ban on the sale of loosies in India. Methods: Data from the 2018-19 Tobacco Control Policy (TCP) India survey (643 current cigarette users and …

Acoustic-Emission Monitoring Of Lap Joint Fatigue Cracks, Siddharth Kannan

Theses and Dissertations

Structural integrity is a pivotal consideration in the field of engineering applications, and understanding the behavior of materials and joints under various loading conditions is critical. This thesis presents a novel approach to detect and analyze fatigue induced cracks in various test specimens using Piezoelectric Wafer Active Sensors. This approach is widely used in Structural Health Monitoring applications involving acoustic emissions that can be captured using PWAS which in turn gives the surface response to applied stresses. The ultimate goal of the research is to identify the length of a fatigue crack originating from lap joints and to develop a …

The Association Between Symptoms Of Adhd And Alcohol Use And Related Consequences In College Students: Social And Environmental Protective And Risk Factors As Moderators Of This Relation, Cameron Shepard Massey

Theses and Dissertations

Alcohol use, while common in college student populations, can bring about significant mental health and educational problems that have negative consequences (Harris et al., 2017; White & Hingson, 2013). Attention-deficit/hyperactivity disorder (ADHD) can also result in significant impairment in academic settings (Kuriyan et al., 2012; Blase et al., 2009, Barbaresi et al., 2007), and those with ADHD often show increased rates of alcohol consumption and related problems, which can greatly increase the risk for students to struggle in college (Barbaresi et al., 2013; Baker et al., 2012). Examining the impact that specific risk and protective factors play in this relation …

Uav-Deployable Sensing Network For Rapid Structural Health Monitoring, Joud Satme

Theses and Dissertations

Natural disasters and extreme weather events pose significant threats to the structural integrity and safety of civil and environmental infrastructure. In this context, Structural Health Monitoring (SHM) emerges as a pivotal discipline, intersecting engineering, technology, and disaster resilience. SHM's mission is to provide real-time, data-driven insights into the condition of critical infrastructure, encompassing bridges, buildings, dams, and transportation networks. These systems not only expedite assessment, but also wield substantial influence in mitigating catastrophic disasters. As the frequency and intensity of extreme weather conditions escalate due to climate change, the need for robust and proactive SHM strategies becomes increasingly apparent. Moreover, …

Digital Health Design For Improving Treatment Decisions, Akanksha Singh

Theses and Dissertations

In the age of artificial intelligence and large datasets, information retrieval by querying large databases is an impossible task for the common user due to the information overload. Recommender Systems (RS) for commercial applications like YouTube, Amazon and Netflix were designed to support users by finding items of interest based on their user profiles and various filtering techniques. Health Recommender Systems (HRS) is a category of RSs that provides immense opportunities for application across several healthcare domains and contexts including treatment decision support. Unlike RS applications that focus on analyzing consumer choices, a key differentiator for HRS applications is the …

An Investigation Into Transcription Fidelity And Its Effects On C. Elegans And S. Cerevisiae Health And Longevity, Olivia S. Dinep-Schneider

Theses and Dissertations

mRNA molecules form an intermediate in the transfer of sequences from DNA to ribosomes in order to guide protein production. Errors can be introduced into mRNA, producing aberrant proteins which place a strain on cellular regulatory machinery, causing increased risks of apoptosis, cancer, and decreased fitness. These errors may be introduced due to decreased transcriptional proofreading capabilities, exposure to chemicals, or mistakes in RNA editing machinery. It is important to investigate these causes of transcription errors to better understand the long-neglected area of mRNA fidelity which has such significant impacts on our cellular functions. In this paper, it was determined …

Impact Of Daily Sweet Potato Ingestion On Alterations To The Gut Microbiome, Cholesterol, And Exercise Performance, Johneric William Smith

Theses and Dissertations

The importance of the gut microbiome is being explored in relation to multiple facets of health and performance. The purpose of this study was to explore the impact of frequent sweet potato ingestion on alterations of the gut microbiome which might in turn alter cholesterol levels and exercise performance. Thirteen recreationally trained males had fecal and blood samples collected and exercised to fatigue with and without exogenous carbohydrate ingestion prior to and following 42 days of daily sweet potato ingestion. Bacterial communities were extracted from fecal samples and bacterial DNA were sequence. Blood samples were analyzed for total cholesterol, low-density …

Not In This House, Satan! An Integrative Framing Analysis Of Body-Positive Posts On Instagram, Gladys Mana Momade

Theses and Dissertations

Scholars have associated the portrayal of idealized images of the body on social media with the negative body image of users, which manifests as several mental health problems such as eating disorders, body dissatisfaction, body dysmorphic disorder, depression, and anxiety in users. To tackle this issue, body-positive (BoPo) influencers on Instagram, having achieved a state of positive body image, post verbal and visual messages to advocate against normative ideologies that foster the negative body image of social media users. These messages have some implications for health communication and body image research. This study analyzes body-positive influencers’ self-assertion and self-expression in …

Food Insecurity In Youth And Young Adults With Diabetes: Prevalence And Association With Health Behaviors, Lauren Helene Martini

Theses and Dissertations

Given the life-long impact of diabetes(1-5), it is important to engage in behaviors that promote health and wellness to delay or prevent negative health outcomes(3, 6-10). Despite this, youth and young adults with diabetes generally do not adhere to nutritional(11-17) or physical activity(18, 19) recommendations. In households experiencing financial difficulties, especially those who are having difficulty providing sufficient food to all of its members, adhering to recommendations may be even more difficult.

The purpose of this dissertation is to better understand and contextualize food insecurity among youth and young adults (YYA) with youth-onset T1DM and T2DM. The first aim addresses …

Memorable Health Messages And Their Influence On Health Behavior, Benjamin Brew Sam-Paintsil

Theses and Dissertations

Students encounter a lot of the health messages they perceive to be relevant. Some of health messages may stick with them for a long period of time and may be easily recalled than others, thus becoming memorable messages to them. Yet, little is known about the content and the source of college students’ memorable health messages. Thus, this study explored the features, the impact, and sources of college students’ memorable health message and whether students view their sources as credible. In addition, the present study examined health issues that students deem as salient in their memorable messages. The study found …