Digital Commons Network^™

Software Defect Rediscoveries: Causes, Taxonomy And Significance, Shyamsundar Kulkarni

Digitized Theses

A software defect rediscovery is a software failure caused by a previously reported defect. It has been observed that a majority of field software failures are rediscoveries which account for typically 50% but sometimes as much as 90% of the total failures. A number of causes for defect rediscoveries have been identified in the literature and solutions have been designed to address some of them. For an organization aiming at reducing the cost due to the rediscoveries, it is important to understand the significance of each of these causes. The significance of each cause will guide the organization to utilize …

Seismic Performance Of Buildings With Multiple Underground Stories, Hesham Mohamed Ei Ganainy

Digitized Theses

This thesis is dedicated to investigate the seismic performance of moment-resisting frame steel buildings with multiple underground stories resting on shallow foundations and to evaluate the current common modeling assumption of analyzing the seismic response of these buildings fixed at the ground surface. The role of the Soil-Structure Interaction (SSI) phenomenon in the seismic design of buildings was extensively reviewed from the structural and geotechnical perspective. The rocking behavior of shallow foundations can greatly affect the seismic response of the supported structures. Thus, one of the main objectives of this thesis is to develop and validate a practical and reliable …

Cultural Codes Of Plagiarism In China: Custom, Law And Morality, Sheng Wu

Digitized Theses

Comparative and interdisciplinary in nature, this thesis decodes the Chinese concept of plagiarism from the perspectives of China’s 5000-year-old customs, its newly adopted copyright law, and its moral tradition, under the theoretical framework of Burton M. Leiser’s philosophical interpretation of social behaviour. Against the backdrop of globalization, this study adopts a new trans-cultural perspective to think about plagiarism in the context of a non-Western national literature and culture, in order to help break the silence in China’s study of plagiarism. It aims to break new ground in approaching the disputes around this subject ignited by some recent plagiarism cases within …

Flexural Design Of Shape Memory Alloy Reinforced Concrete Sections For Strength And Serviceability Requirements, Yamen Ibrahim Elbahy

Digitized Theses

Superelastic shape memory alloys (SMAs) have the ability to recover plastic deformations upon unloading. This unique property has motivated researchers to utilize them as primary reinforcement for RC structures located in seismic regions. The lack of understanding the behaviour of SMA RC sections is constraining their use. This thesis investigates the flexural behaviour of SMA RC sections. The validity of the flexural design equations provided by the Canadian Standards for SMA RC sections is evaluated. The load-deflection behaviour of SMA RC members is also investigated. The results are used to assess the applicability of available deflection models for SMA RC …

Unpainted Sky: 17th And 18th Century Naturalism In Korea And Europe, Eunjoo Lee

Digitized Theses

This thesis examines comparative aesthetics focusing on Korean and European naturalism in the seventeenth and eighteenth centuries. In this thesis I consider the different ways of understanding and depicting humankind and nature, and how these different perceptions affect the concept of naturalism in each culture, since the way Koreans perceive nature and naturalism is very different from European naturalism. While Korean naturalism can be described as the respect for and meditation on nature, European naturalism can be linked more closely with imitation of nature. This thesis focuses on naturalism in terms of the notion of Emptiness and Being in each …

Regional Infiltration Of Meteoric Water Into The Mira Terrane: A Stable Isotope Study Of The Avalonian Huntington Mountain Pluton And Related Rocks, Cape Breton Island, Canada, Duane C. Petts

Digitized Theses

The Avalonian Mira terrane of Cape Breton Island, Nova Scotia, Canada is composed mainly of late Proterozoic volcanic-plutonic-sedimentary rocks that formed in an evolved magmatic arc along the margin of Gondwana. The purpose of this study is to determine the source(s) and timing of the 18O-depletion that has affected the 620 Ma Huntington Mountain pluton and East Bay Hills volcanic suite of the Mira terrane. Plutonic and volcanic rock samples have oxygen-, hydrogen- and carbon-isotope values of-6.3 to +14.3‰, -93 to -56‰, and -7.4 to +0.1‰, respectively. These values likely signal the interaction of meteoric-dominated hydrothermal fluids with the Himtington …

Towards The Identification Of A Putative Type Iπ-Like Secretion System Chaperone, Hp1382, And Putative Type-Iii Like Secreted Glycoproteins, Hp0235 And Hp1563, In Helicobacter Pylori, Jaspreet Chahal

Digitized Theses

Putative type III secretion system (TTSS)-Iike proteins were identified in silica in H. pylori. These include two cargo proteins, HP0235 and HP1563 (TsaA) and one chaperone, HP1382. The cargo proteins may be secreted via the H. pylori flagellum in a TTSS-like manner. Two experimental approaches were implemented to identify interacting partners of the TTSS-like proteins. First, HP0235 and HP13 82 were TAP- tagged and introduced into H. pylori. HP0235 was co-purified with its associating partners by IgG affinity chromatography, but low protein expression and recovery prevented downstream analyses. Expression of HP1382 was not inducible by any condition known to induce …

Design Of Transverse Gradient Coil Technology For Dynamic Manipulation Of Image Volume In Mri, Carl Gazdzinski

Digitized Theses

The aim of this thesis was to investigate the capabilities of a novel gradient concept for the purpose of dynamic manipulation of imaging volume and gradient performance in Magnetic Resonance Imaging (MRI). The proposed concept exploits the natural inverse co-dependence between the gradient strength of the coil generated magnetic field profile, and the volume over which the gradient is uniform, to optimize gradi­ ent performance for a given anatomical region of interest. The design also has the potential to extend the available range of gradient performance within the operation constraints imposed by gradient induced Peripheral Nerve Stimulation (PNS). A de­ …

The Role Of Rip2 In Vascularized Allograft Rejection, Todd Fairhead

Digitized Theses

Two previous reports that RIP2 knockout (RIP2) mice had defective NF-κB signaling and Thl immune responses had led to the belief that this putative serinethreonine kinase might be a possible target for transplant immunosuppression. Thus, we tested whether RIP2 mice were able to reject vascularized allografts. Surprisingly, we found that T cells from RIP2= mice proliferated and produced IFNγ after allostimulation in vitro. Moreover, naïve RIP2/ CD4+ T cells differentiated normally into Thl or Th2 cells under appropriate cytokine microenvironments. Consistent with these findings, no difference in allograft survival was observed between wild type and RIP27 recipient mice, and rejection …

Cross-Layer Optimization Of Network Performance Over Mimo Wireless Mobile Channels, Marco Luccini

Digitized Theses

In the information theory, the channel capacity states the maximum amount of in­ formation which can be reliably transmitted over the communication channel. In the specific case of multiple-input multiple-output (MIMO) wireless systems, it is well recognized that the instantaneous capacity of MIMO systems is a random Gaussian process. Time variation of the capacity leads to the outages at instances when it falls below the transmission rate. The frequency of such events is known as outage probability.

The cross-layer approach proposed in this work focuses on the effects of MIMO capacity outages on the network performance, providing a joint optimization …

Patterns Of Expatriate Deployment Over Time And Subsidiary Evolution, M. Suhaib Riaz

Digitized Theses

Deployment of expatriates in international subsidiaries can be a complex issue for multinational enterprises (MNEs). The global environment is increasingly integrated across national borders, and yet there remain critical differences among national environments. Consequently, expatriate employees can be an important resource as MNEs try to make sense of, and enact, their environments across the globe. This study focuses on the changes in deployment of expatriates in international subsidiaries as a window into understanding MNE parent-subsidiary issues in a dynamic manner. Most extant research has considered the MNE expatriate deployment phenomena in a static manner, in line with research on international …

Nursing Career Stress Prevention By Baccalaureate Nursing Education: Faculty Views, Jason S. Mccready

Digitized Theses

Nursing career stress (NCS) will continue to gain prominence as impacts of the nursing shortage worsen. Measures targeting NCS are well researched, although predominately focus on the existing workforce and/or workplaces. Little exploration has occurred about preventing nurses’ stress prior to workforce entry. Baccalaureate nursing education (NE) has unparalleled access to, and influence with, nursing students (NS). It is thus proposed that explicitly preparing NSs for realities of nursing practice and work life can prevent exposures to NCS, ameliorate responses to it, and prevent its negative outcomes. Stress prevention/management has previously been incorporated into baccalaureate curricula; however, in all cases …

Improved Consistency Of Resistance Spot Welding Via Power Supply Control Strategy, Jing Bai

Digitized Theses

Resistance spot welding (RSW) is widely used as an efficient joining technology for assembling metal components in the automotive, biomedical and electronics industry. The demand for improved welding consistency has led to switching from voltage control to current control. In addition, commercially available micro-spot welders may also provide power control mode.

Power can be interpreted as the square root of the geometric mean of voltage and current. From this view point, the three existing power strategies can be seen as differently weighted geometric means of voltage and current. In fact, any weighted mean of voltage and current can be used …

Objective Evaluation Of Tracheoesophageal Speech Quality, Rob Mcdonald

Digitized Theses

It remains important to have accurate and reliable ways of measuring voice quality in speech communications systems and in abnormal voice assessment and rehabilitation. It is also beneficial to have objective measures of speech quality as opposed to subjective, in order to save time, money and other such resources. Objective measures of speech quality are typically divided into two groups: “intrusive” and “non-intrusive” measures. Intrusive measures require the knowledge of both the input speech along with the output of the system under test. Non-intrusive measures on the other hand only require access to the output speech signal of the system. …

Pattern Recognition Of A Gravitational Wave Pulsar Signal, Marc Eric Normandin

Digitized Theses

The direct detection of Gravitational Waves (GWs) is one of the most challenging problems in experimental gravitation today. It warrants the use of highly advanced large laser interferometers such as LIGO, VIRGO, LISA, TAMA 300, GEO 600 and AIGO. The analysis of the data from such instruments requires and combines the expertise from a multitude of scientific disciplines. The verification of a detected signal demands an effective way to distinguish the source signal from the background noise. Such a study is required for an all-sky search to determine the φ and θ angles on the sky of gravitational wave sources …

Inspection Point Accessibility, Clustering And Path Planning For Laser Scanning, Abelardo Escoto

Digitized Theses

Laser scanners are widely used in quality control. Currently, the operation and programming of laser scanners is done manually. An efficient way of using this machine can save a considerable amount of time and money. This thesis develops several algorithms for the development of an off-line automated inspection planning system for laser scanners, focusing on inspection point visibility, clustering methods, and collision free path planning. A mathematical definition of the probe head motion and pose around the inspection point is presented. The visibility cones of given inspection points are calculated using graphics hardware rendering and image processing. Then the pixel …

Immersed Boundary Conditions Method For Analyzing Motion Of Second-Order Fluid Over Corrugated Boundaries, Alireza Mohammadi

Digitized Theses

A spectral method for solving the flow of a second-order fluid is developed for the case of a planar channel with corrugated boundaries. The proposed algorithm employs a fixed computational domain. The boundaries of the flow domain are located inside the computational domain. The flow boundary conditions are imposed using the concept of immersed boundary conditions. The algorithm relies on Fourier expansions in the flow direction and Chebyshev expansions in the transverse direction. Various tests confirm spectral accuracy ofthe algorithm.

Palimpsest: Rewriting The Therapeutic Relationship Through A Critically Reflexive Lens, Lisa Carroll Mccorquodale

Digitized Theses

“Good” and “bad” clients traditionally define successful therapeutic relationships between clients and occupational therapists. Such dichotomies are over-simplistic, and lack contextual understanding. An alternative is for therapists to engage with critical reflexivity in an attempt to see therapeutic relationships as more complex. In this manner one can adopt a posture Maxine Greene (1973) calls “making strange” whereby one re-examines that which is taken as given in therapeutic relationships. This critical autobiographical research sought to gain a deeper understanding of critical reflexivity in therapeutic relationships. I began by authoring an autobiographical text that was a personal examination of my experiences with …

Instrumentation And Control System Development For Interfacial Force Microscopy, Asghar Mesbah Nejad

Digitized Theses

The Interfacial Force Microscope (IFM) is a modification of the Atomic Force Micro­ scope (AFM) which works on the basis of a force-balancing capacitive sensor. It was originally developed for measuring force-displacement curves in studying surface prop­ erties of materials. Furthermore, IFM can be used in topography measurements and nanomanipulation. IFM has superior capabilities over other members of the Scanning Probe Microscope (SPM) family for biomedical applications. This is mainly because of its longer and more rigid tip, which makes it easy to use inside live cells without significant changes in its characteristics.

Performance of the current IFM system is …

Identitication Of ‘Carboxylate Clamp’ Type Tetratricopeptide Repeat Proteins In Arabidopsis Using In Silico Approaches, Shilpi Goel

Digitized Theses

The highly conserved and abundant cystosolic molecular chaperone Hsp90 plays a key role in signal transduction networks, cell-cycle control, protein degradation and protein trafficking. Two key features regarding the mechanism of Hsp90 action are: 1) Hsp90 operates as part of a multichaperone complex, facilitating the folding of the client proteins into their stable or activatable conformations, and 2) Hsp90 functions are driven by the hydrolysis of ATP. The functional cycle of Hsp90 requires a cohort of co­ chaperones that regulate the ATPase activity of Hsp90 and confer specificity to its interaction with client proteins. Several Hsp90 co-chaperones contain the tetratricopeptide …

Patients Undergoing Shoulder Surgery Can Accurately Recall Their Preoperative Health Status Two Weeks Postoperatively, Zachary H. Rosen

Digitized Theses

Objective: To evaluate the ability of shoulder surgery patients to recall their preoperative health status two weeks postoperatively. Study Design: We randomized consecutive patients to group I (assessments at 2 weeks preoperatively, on the day of surgery, and 2 weeks and 6 months postoperatively) or group II (assessments at 2 weeks and 6 months postoperatively). At each visit patients completed disease-specific, region-specific, and generic health instruments. At 2 weeks postoperatively, patients completed the same questionnaires according to their recollection of their health 2 weeks prior to surgery. Results: Agreement between actual and recalled data was excellent for diseasespecific (ICCworc = …

Oxide Film Formation And Conversion Mechanism On Carbon Steel Under Mildly Basic Conditions, Wei Yu

Digitized Theses

Understanding the factors that can affect the corrosion of steel pipes or containers is an important concern for nuclear power plants. Corrosion involves metal oxidation and dissolution, and hence, its kinetics depends on the aqueous redox condition and the physical and chemical nature of surface oxide formed during corrosion. Nuclear plant environment includes the additional challenge of fields of ionizing radiation that can affect the redox conditions in solution. To develop a fundamental understanding of radiation induced corrosion, the kinetics of steel corrosion in aggressive and dynamic redox conditions that simulate radiolytic environments are being studied. The objective of this …

Oxygen Uptake Kinetics During Heavy Cycling Versus Knee-Extension Exercise And Effect Of Prior Heavy Exercise, Sarah M. Cleland

Digitized Theses

The effects of prior heavy-intensity exercise (HI) on VO2 kinetics were examined during subsequent heavy-intensity exercise (H2) in upright cycle (CE) and alternate-leg kneeextension (KE) ergometιy in 9 subjects. VO2 was measured breath-by-breath. Oxygenated (O2Hb), deoxygenated (HHb) and total (Hbtot) haemoglobin/myoglobin of the vastus lateralis were monitored by near-infrared spectroscopy. Prior exercise had no significant effect on the primary time constant (τp VO2 ) in either mode, but increased the amplitude and/or asymptotic primary VO2 with A[O2Hb], A[Hbtot] and primary Δ[HHb] amplitudes greater (P < 0.05) in H2 versus Hl in both modalities. Priming resulted in both a reduced (P < 0.05) slow component Vo2 amplitude and muscle deoxygenation in CE and KE. These results suggest increased muscle O2 availability and O2 extraction increased the primary VO2 response but did not affect the τpVθ2, and heavy priming attenuated the VO2 slow component amplitude with enhanced O2 availability and decreased muscle deoxygenation in both modes.

Numerical Modelling And Performance Of Reinforced Concrete Members Under Fire Condition, Mohamed Moftah

Digitized Theses

A thermo-mechanical finite element model is developed to study the behaviour of reinforced concrete columns and beams exposed to fire. Two different analyses are included in this model. A three-dimensional nonlinear transient heat conduction analysis that takes into account the variation of the thermal properties of concrete with temperature is first conducted. The temperature profile resulting from the exposure of a reinforced concrete member to fire is determined by the heat transfer analysis and is then exported to a stress analysis model. A special nonlinear fibre frame element is used in this model. The stress analysis incorporates a material model …

On Neurovascular Regulation Of Primary Visual Cortex: Neuronal Activity And Hemodynamics, Zheng Wang

Digitized Theses

Modem brain functional imaging techniques like functional magnetic resonance imaging (fMRI) mostly infer alterations of neuronal activities by mapping local changes in cerebral blood flow (CBF) or metabolism. The understanding of the relationship between neuronal activity and the hemodynamic responses, the so called neurovascular coupling, is critical for the interpretation of signals like the blood-oxygenation-level- dependent (BOLD) effect. The neurovascular regulation is modeled by a linear transform model in the fMRI experiments, which allows making an inverse inference from BOLD to neuron. Some recent reports suggest that the BOLD response is a nonlinear function in the time domain. Because changes …

Metabolic Patterns During The Early Life History Of Rainbow Trout (Oncorhynchus Mykiss), Kristen M. Vandekieft

Digitized Theses

Much is known about carbohydrate metabolism in adult fish, however virtually

nothing is known about this in early life stages. The purpose ofthis study was to examine carbohydrate metabolism at various stages of early development (from fertilization to free-feeding) in rainbow trout (Oncorhynchus mykiss). Total body glycogen and free glucose increased throughout development, with the greatest changes occurring at hatch and free-feeding stages. Lactate content increased 3-fold at hatch, and persistedthroughfree-feeding. Glycogenphosphorylaseactivitywasnotdetecteduntil 21 dpf and lactate dehydrogenase activity (LDH) not until hatch. Taken together, the increase in glycogen phosphorylase, LDH and glycogen content suggests that embryos areinpreparationforlocomotoryactivityfollowinghatch. Consistentwiththisidea, dechorionated embryos …

Influence Of Patient Familiarization On The Internal Loads Of The Knee Joint Due To An Off-The-Shelf Versus A Custom-Fit Unloader Brace, Kristin D. Whitney

Digitized Theses

A common conservative treatment for knee osteoarthritis is the use of an ‘unloader’ brace. Although many studies have been conducted on unloader braces, the actual effect of the brace on internal knee joint loading remains unclear.

This study examined the internal effects of a custom-fit and an off-the-shelf unloader brace on the reduction of loading within the affected compartment of an Osteoarthritic knee joint using three-dimensional (3D) gait analysis and a novel 3D, mathematical model of the knee joint.

The loading results were compared to evaluate differences between the braced and the unbraced conditions. No conditioning effect was seen in …

Intertextuality, Pastiche, And Allegory In Postmodern Aesthetics: An Analysis Of Enrique Vila-Matas, Cindy Sherman, And Cristina Peri-Rossi, Samanta Ordonez Robles

Digitized Theses

This thesis explores three aspect of postmodern aesthetics: intertextuality, pastiche, and allegory. The role that intertextuality plays in postmodernism is analyzed in Bartleby & Co. (2000), a novel by Vila-Matas. This analysis draws upon and critiques Julia Kristeva's understanding of intertextuality, and is prefaced with a consideration of medieval and modernist intertextuality. Postmodern pastiche is analyzed with reference to Cindy Sherman's "History Portraits" and "Untitled Film Stills," while Cristina Peri Rossi's The Ship of Fools (1984) provides the context in which to explore allegory. In the chapter dedicated to pastiche, I challenge the way in which Linda Hutcheon and Fredric …

Identification Of A Novel Isoform Of Secretory Pathway Calcium Atpase 2 (Spca2), Victoria Catherine Garside

Digitized Theses

The proper regulation of cytosolic Ca is critically important to the function of pancreatic acinar cells, as they require Ca oscillations to initiate the exocytosis of their digestiveenzymes. PersistentlyhighlevelsofcytosolicCa2+leadstotheimproper

activation of these digestive enzymes and subsequently could lead to the development of pancreatic diseases, such as pancreatitis. A series of channels and pumps exist to maintain appropriate levels of cytosolic Ca2+, such as the sarcoendoplasmic reticulum Ca2+ ATPases (SERCAs), plasma membrane Ca2+ ATPases (PMCAs) and the secretory

pathway Ca2+ ATPases (SPCAs). Using Northern blot and real time RT-PCR analysis, I have confirmed the presence of a novel isoform of SPCA2, …

Software For Modeling Ultrasound Breast Cancer Imaging, Yi-Ting Shen

Digitized Theses

Computer-based models are increasingly used in biomedical imaging research to clarify links between anatomical structure, imaging physics, and the information content of medical images. A few three-dimensional breast tissue software models have been developed for mammography simulations to optimize current mammography systems or to test novel systems. It would be beneficial in the development of ultrasound breast imaging to have a similar computational model for simulation. A three-dimensional breast anatomy model with the lobular ducts, periductal and intralobular loose fibrous tissue, interlobular dense fibrous tissue, fat, and skin has been implemented. The parenchymal density of the model can be varied …