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Articles 1 - 30 of 53
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Side Channel Detection Of Pc Rootkits Using Nonlinear Phase Space, Rebecca Clark
Side Channel Detection Of Pc Rootkits Using Nonlinear Phase Space, Rebecca Clark
Honors Theses
Cyberattacks are increasing in size and scope yearly, and the most effective and common means of attack is through malicious software executed on target devices of interest. Malware threats vary widely in terms of behavior and impact and, thus, effective methods of detection are constantly being sought from the academic research community to offset both volume and complexity. Rootkits are malware that represent a highly feared threat because they can change operating system integrity and alter otherwise normally functioning software. Although normal methods of detection that are based on signatures of known malware code are the standard line of defense, …
Impostor Phenomenon, Perfectionism, Psychological Distress, And Burnout In Pre-Health Undergraduate Students, Victoria Lee
Impostor Phenomenon, Perfectionism, Psychological Distress, And Burnout In Pre-Health Undergraduate Students, Victoria Lee
Honors Theses
Preparing for a career in the healthcare field is incredibly strenuous and demanding, and previous research endeavors have demonstrated that students in professional healthcare programs show an increased susceptibility to impostor phenomenon, perfectionism, psychological distress, and burnout. Previous studies have indicated a possible link between impostor phenomenon, perfectionism, psychological distress, and burnout; however, these studies only considered two or three constructs at a time in graduate students (Rosenthal, et al., 2021; Seong, et al., 2020; Garratt-Reed, et al., 2018). The current study’s purpose was to investigate the whether or not impostor phenomenon, perfectionism, and psychological distress could be potential predictors …
Cell Type-Specific Production Of Amyloid Precursor Protein During Infection Is Dependent On The Strain Of Herpes Simplex Virus 1, Mia Elias
Honors Theses
Cleavage of amyloid precursor protein (APP) generates the antimicrobial peptide amyloid beta (Aβ), the accumulation of which is linked to Alzheimer’s Disease (AD) pathogenesis. Whether processing of APP contributes to anti-viral responses is debated. Herpes Simplex Virus Type 1 (HSV-1), a neurotropic double-stranded deoxyribonucleic acid (DNA) virus, establishes lifelong latency and can cause a range of outcomes, from asymptomatic infection to herpetic encephalitis (HSE). Whether disparate outcomes are dependent on HSV-1 strain is unknown. Using three differentially virulent HSV-1 strains, we compared the regulation of APP-associated proteolytic processing in both a corneal infection murine model and an in vitro model. …
Imagined Intergroup Contact As A Mechanism To Change Beliefs About Gender, Samantha Oyler
Imagined Intergroup Contact As A Mechanism To Change Beliefs About Gender, Samantha Oyler
Honors Theses
Gordon Allport first proposed the Intergroup Contact Theory in 1954. According to his theory, contact between ingroup and outgroup members, under certain conditions, would lead to positive effects, specifically the reduction of prejudice. Since then, this theory has been expanded to include members of other majority/minority groups. Research suggests intergroup contact has positive effects for reduction of anti-trans prejudice. To date, the focus has largely been on the mechanisms driving changes in attitudes and intentions towards trans individuals through intergroup contact interventions. It is unclear whether this intervention might also promote the acquisition of more nuanced sociocultural understanding about gender, …
Phase Equilibria And Heat Capacities For Tetraarylphosphonium-Based Ionic Liquids, Allan Wilson
Phase Equilibria And Heat Capacities For Tetraarylphosphonium-Based Ionic Liquids, Allan Wilson
Honors Theses
Climate change is one of the most pressing issues facing humanity in the 21st century. A major contributing factor to this problem is the continued use of fossil-fuel based sources for energy. Concentrated solar power (CST) with thermal energy storage (TES) provides a potential opportunity to support this transition away from fossil fuels but suffers from high costs and extended downtimes. Current heat transfer fluids used in these processes often consist of a mixture of alkali metal nitrates with melting points above 200°C. For CST and TES to be viable, a thermally stable, low melting fluid is needed. Ionic liquids …
Meta Project: Construction, Validation, And Flight Testing Of A New Meta Aircraft Design, William Andrew Wearren
Meta Project: Construction, Validation, And Flight Testing Of A New Meta Aircraft Design, William Andrew Wearren
Honors Theses
Meta aircraft are a type of aircraft that can connect via wingtip, nose-to-tail, or both wingtip and nose-to-tail in order to create a lattice of aircraft that can fly together to a site, detach, survey different areas, and then reattach for flight back to the main base. The project started at the Georgia Institute of Technology with Dr. Carlos Montalvo and is being continued at the University of South Alabama Facility for Aerospace Systems and Technology Lab. This paper seeks to theoretically verify the new aircraft design for the META project, complete the development of the design, and to experimentally …
Investigating Thin Filament Assembly In C. Elegans Muscles, Angela Russ
Investigating Thin Filament Assembly In C. Elegans Muscles, Angela Russ
Honors Theses
All striated muscles are composed of small units called sarcomeres [1]. Within each sarcomere, there are thin filaments composed of actin and thick filaments composed of myosin. The thin filaments extend from either end of the thick filament towards the middle of the sarcomere. The lengths of thin filaments are correlated to muscle contraction and force production [1], but it is currently unknown what regulates their lengths. Prior hypotheses based on vertebrate models have focused on a nebulin ruler model [2]. However, nebulin is not present within invertebrate muscles, and this has led to a major gap in the field’s …
Civil Disobedience Of Social Workers In Hospice, Jamie Leigh Roper
Civil Disobedience Of Social Workers In Hospice, Jamie Leigh Roper
Honors Theses
No abstract provided.
The Tripartite Influence Model Of Body Image And Disordered Eating Among Female Athletes: Testing An Expanded Model, Emma Nyrup Tonsberg
The Tripartite Influence Model Of Body Image And Disordered Eating Among Female Athletes: Testing An Expanded Model, Emma Nyrup Tonsberg
Honors Theses
The aim of the study was to investigate how different sources of sociocultural pressure (family, media, peers) described in the Tripartite Influence Model, and additions of teammate- and coach pressures, were associated with thinness-and muscularity internalization and appearance comparisons among athletes. Subsequently, these potential mechanisms were explored as predictors of disordered eating among athletes. Analyses included 71 female athletes. Athletes were recruited through a student subject pool recruitment portal, as well as with local and regional flyers and emails. Participants completed a series of self-report measures in Qualtrics. Hierarchical linear regression analysis was utilized to test the hypotheses. Partial support …
Evolution Of Medical Ethics During The American Civil War, Luke Love
Evolution Of Medical Ethics During The American Civil War, Luke Love
Honors Theses
This thesis will explore the relationship between medical ethics and the American Civil War through a microhistorical approach. This includes analyzing the ways in which the physician-patient relationship was conducted and which medical practices were deemed ethical and by whom. Changes that occurred in medical ethics during the war will be analyzed and explained. v
Emotion Regulation And Media Use In Young Children, Brianna Dixon
Emotion Regulation And Media Use In Young Children, Brianna Dixon
Honors Theses
Child screen time has increased tremendously in the past several years because of new technological advances. This is a great resource for some individuals on a limited basis. However, many children are being taught to regulate their emotions through media use. The initial aim of this study was to attempt to find a correlation between parent reported screen time and problematic media use. It was hypothesized that higher reported screen time would be significantly related to greater problematic media use and that higher reported screen time and problematic media use would be related to a greater negative reaction in screen …
Sdrnas Participate In The Maintenance And Onset Of Prostate Cancer, Neil Y. Chaudhary
Sdrnas Participate In The Maintenance And Onset Of Prostate Cancer, Neil Y. Chaudhary
Honors Theses
No abstract provided.
Survey Of The Bolctes From Fish River Nature Preserve, Noah T. Nelson
Survey Of The Bolctes From Fish River Nature Preserve, Noah T. Nelson
Honors Theses
Boletes are a special kind of mushroom inside of the Kingdom Fungi that are distinguished from other mushrooms by their uniquely pored hymenium, as opposed to gills. Many boletes are ectomycorrhizal, meaning they are mutualists with vascular plants, and thus beneficial to the overall health of the terrestrial ecosystem. Some are well-known for their edibility and are of economic importance. In the United States 59 genus-level clades comprising 290 operational taxonomic units have been reported. The southeastern US and Gulf Coast regions however are less researched and recorded for their mushroom ecology. In Alabama, only 56 bolete species have been …
Formation Of Diazirine Functionality For Propellant Applications, Abby Mock
Formation Of Diazirine Functionality For Propellant Applications, Abby Mock
Honors Theses
Our research focuses on a cost-effective approach which minimizes synthetic overhead when assembling compounds with diazirine functionality. The goals are to prevent the surplus use of ammonia in the formation of diaziridine functionality and use an IKA Electrosyn 2.0 in the oxidation of diaziridine functionality. Success with either specific aim will significantly reduce the synthetic overhead currently observed. Diazirine functionality plays a vital role in a vast number of applications. Two of interest to us include diazirine functionality as a next generation propellant and as a photoaffinity label. With the latter, this strategy plays a vital role in drug discovery …
Development And Validation Of A Noninvasive, Portable, And Low-Cost Device To Detect Peripheral Artery Disease, Julia Louise Nelson
Development And Validation Of A Noninvasive, Portable, And Low-Cost Device To Detect Peripheral Artery Disease, Julia Louise Nelson
Honors Theses
Peripheral Artery Disease (PAD) is a progressive cardiovascular condition characterized by atherosclerosis in the extremities. It affects up to 10 million adults in the United States and is associated with an elevated risk of heart attack and stroke. Up to 50% of people with PAD are asymptomatic and undiagnosed. This presents the need for a rapid, inexpensive, and noninvasive screening tool that can be easily used to diagnose PAD. We developed a device, REFLO (Rapid Electromagnetic FLOw device), to detect low blood flow and diagnose PAD. The device uses lowpower radio frequency energy (35 GHz) to heat the skin and …
Dna Methylation Of The Agtri Promoter In A Hypertensive Population Of Kenyans, Michael M. Roque
Dna Methylation Of The Agtri Promoter In A Hypertensive Population Of Kenyans, Michael M. Roque
Honors Theses
Cardiovascular disease (CVD), the leading cause of death worldwide, is rapidly increasing in low-and middle-income countries (LMICs). particularly those of Sub Saharan Africa (SSA). Hypertension is the leading risk factor for CVD and is a multifactorial disease with no single genetic cause. Increasingly, evidence indicates that hypertension is predisposed by environmental regulation of genes through heritable, yet modifiable, epigenetic changes to DNA leading to changes in gene expression. e.g. methylation. While understanding the etiology of hypertension in LMICs is a global priority, few epigenetic studies exist from populations living in SSA. The renin arigiotensin system (RAS) is the primary hormonal …
Ensuring Non-Repudiation In Long-Distance Constrained Devices, Ethan Blum
Ensuring Non-Repudiation In Long-Distance Constrained Devices, Ethan Blum
Honors Theses
Satellite communication is essential for the exploration and study of space. Satellites allow communications with many devices and systems residing in space and on the surface of celestial bodies from ground stations on Earth. However, with the rise of Ground Station as a Service (GsaaS), the ability to efficiently send action commands to distant satellites must ensure non-repudiation such that an attacker is unable to send malicious commands to distant satellites. Distant satellites are also constrained devices and rely on limited power, meaning security on these devices is minimal. Therefore, this study attempted to propose a novel algorithm to allow …
Events To Record: An Examination Of Required Activation For Body-Worn Cameras, Allison Reed
Events To Record: An Examination Of Required Activation For Body-Worn Cameras, Allison Reed
Honors Theses
There has been a lot of research on the effectiveness of body-worn cameras in policing including the impacts that body-worn cameras have on police officers, individual citizens, and the community. Results from prior literature show that police body-worn cameras are only sometimes highly effective. This project investigates why police body-worn cameras may not be effective by examining the required activation policies. Data for this project derive from the 2016 Law Enforcement Management Administrative Statistics – Body-Worn Camera Supplement (LEMAS-BWCS) study conducted by the Bureau of Justice Statistics. The main components of these data are the required events officers are to …
Effect Of Temperature On The Microbiome Of A Laboratory-Reared Colony Of Haemaphysalis Longicornis Ticks, Brianna L. Mitchell
Effect Of Temperature On The Microbiome Of A Laboratory-Reared Colony Of Haemaphysalis Longicornis Ticks, Brianna L. Mitchell
Honors Theses
Haemaphysalis longicornis ticks are invasive to the United States with potential to transmit several tick-borne pathogens that are native to the United States. Based on existing locations of H. longicornis in its native regions in Asia, as well as its invasive populations that are established in the United States, several geographic range prediction models have been produced to help understand future range expansion and distribution of this invasive tick in North America. Unfortunately, these models do not all agree and there is uncertainty associated with the potential geographic range expansion of H. longicornis ticks in North America. Climate can affect …
Role Of Pseudomonas Aeruginosa Exoenzymes S, T, And Y In The Modulation Of Intrinsic Apoptosis In Pulmonary Microvascular Endothelial Cells, Andrea M. Vavrinek
Role Of Pseudomonas Aeruginosa Exoenzymes S, T, And Y In The Modulation Of Intrinsic Apoptosis In Pulmonary Microvascular Endothelial Cells, Andrea M. Vavrinek
Honors Theses
P. aeruginosa is the most common cause of ventilator-associated pneumonia in ICU patients. P. aeruginosa uses a type III secretion system to inject exoenzymes S, T, U, and Y into host cells, exhibiting unique effects. Pulmonary microvascular endothelial cells (PMVECs) are used to evaluate cellular changes caused by exoenzymes. ExoY infection of PMVECs leads to cell rounding but does not lead to cell death, unlike ExoS/T. The current study evaluated the exoenzyme-induced modulation of intrinsic apoptosis in endothelial cells. Strain PAK, producing ExoS, T, and Y, was compared to isogenic strains expressing either S, SY, T, TY, Y, or none …
Examining Ndufab1 Expression In Head And Neck Squamous Cell Carcinoma, Addison L. Stevens
Examining Ndufab1 Expression In Head And Neck Squamous Cell Carcinoma, Addison L. Stevens
Honors Theses
Head and neck squamous cell carcinoma (HNSCC) accounts for around 4% of all cancers in the USA. HNSCC includes cancers of the oral cavity, oropharynx, nasopharynx, hypopharynx, and larynx. Reprogramming of mitochondrial metabolism has been known to promote oncogenesis. NDUFAB1, a nuclear encoded subunit of respiratory complex I (RCI) in the inner mitochondrial membrane, is abundantly expressed at the mRNA level in HNSCC patients. Based on this finding, we hypothesize that NDUFAB1 protein expression is high in HNSCC and that NDUFAB1 expression predicts a poor prognosis in HNSCC patients. We determined NDUFAB1 expression in HNSCC using immunohistochemistry and pathology guided …
Descriptive Representation In State Legislatures: Exploring The Educational Backgrounds Of State Representatives And Senators, Skylar Dykes
Descriptive Representation In State Legislatures: Exploring The Educational Backgrounds Of State Representatives And Senators, Skylar Dykes
Honors Theses
This project will investigate the influence of descriptive representation as it pertains to efficacy in a democratic system. It is possible that policy outputs are heavily dependent upon motivations of an elected official, even more so than the anticipated or predictable effects of an ideological stance. We expect that, following the juxtaposition of a state legislator’s voting records with his or her biographical data, these claims will be supported by data related to higher education and its funding allocations. We are especially interested in the specific relationship between the educational background of state legislators, and whether or not a correlation …
Deficits In Health Literacy And Inadequacies Of Specialized Health Care In The South For Deaf And Hard Of Hearing Patients, Kaleb Kittrell
Deficits In Health Literacy And Inadequacies Of Specialized Health Care In The South For Deaf And Hard Of Hearing Patients, Kaleb Kittrell
Honors Theses
Health literacy is a constantly evolving concept that requires similarly evolving adaptation and specialization of health care to increase the quality of life for all. One demographic that is largely ignored when it comes to research in health literacy, specifically in the traditional South, is the d/Deaf and hard of hearing/Hard of Hearing (DHH) population. The purpose of this study is to determine the general health literacy of this specific demographic and compare results with that of other demographics to highlight the anticipated deficit in health literacy levels and emphasize the critical need for specialized care. This prospective, non-experimental, descriptive …
Comparing Composite Severe Weather Indices Of Thunderstorm Activity On Sea-Breeze And Non-Sea-Breeze Days In The Mobile, Alabama Area, Elizabeth Seiler
Comparing Composite Severe Weather Indices Of Thunderstorm Activity On Sea-Breeze And Non-Sea-Breeze Days In The Mobile, Alabama Area, Elizabeth Seiler
Honors Theses
Sea breezes (SB) occur frequently from May through October along the U.S. Gulf of Mexico Coast. One reason why SBs interest forecasters is their ability to spawn summertime thunderstorms, which can cause flash flooding, lightning, and hail. However, forecasting the exact timing and location of SB-driven convection can be challenging. This thesis will focus on Mobile and Baldwin Counties in southwest Alabama, which experience two types of phenomena – SBs along the Gulf of Mexico Coast and bay breezes on either side of Mobile Bay. Over the past years, multiple undergraduate students have analyzed Mobile, Alabama radar imagery of past …
Applying Mci-062, A Novel Pan-Ras Inhibitor, To Treat Kras-Mutant Lung Cancer, Richard Fu
Applying Mci-062, A Novel Pan-Ras Inhibitor, To Treat Kras-Mutant Lung Cancer, Richard Fu
Honors Theses
RAS is a prevalent oncogene that is mutated in 27% of human cancers. Gain-of-function RAS mutations activate multiple downstream pathways, including the RAS-RAF-MEK-ERK and PI3K/AKT/mTOR pathways, which are critical in tumorigenesis and cancer cell proliferation. RAS proteins such as KRAS, a member of the RAS protein family, and their downstream effectors are attractive targets for cancer therapy since their mutations act as frequent drivers in lung, colorectal, and pancreatic cancers. However, RAS proteins have relatively smooth surfaces that lack traditional binding pockets, making inhibitors specific to RAS difficult to create. Recently, a novel small molecule pan-RAS inhibitor named MCI-062 was …
Lost In Time And Lost In Space: Chronotopes In Thomas Pynchon’S Against The Day, Stephen Margavio
Lost In Time And Lost In Space: Chronotopes In Thomas Pynchon’S Against The Day, Stephen Margavio
Honors Theses
In his 1937 essay “Forms of Time and of the Chronotope in the Novel,” Russian literary theorist Mikhail Bakhtin coins the term “chronotope” to discuss the inherently interconnected nature of time and space in narrative constructions. According to Bakhtin, there are a number of specific chronotopes (or space/time configurations) that help to define literary genres. Applying Bakhtin’s concepts to Thomas Pynchon’s novel Against the Day (2006), this thesis examines how the idea of narrative space/time can clarify Pynchon’s use of genre to make socio-political commentary. The first chapter of this thesis focuses on Bakhtin’s “road chronotope,” which is characterized by …
Utilizing Acoustic Levitation To Determine Ionic Liquid Effects On Enthalpy Of Polymerization, Davina V. Ho
Utilizing Acoustic Levitation To Determine Ionic Liquid Effects On Enthalpy Of Polymerization, Davina V. Ho
Honors Theses
Ionic liquids (ILs) are emerging as an eco-friendlier alternative to traditional organic compounds. The hope with ILs in this project is to incorporate them with resins used in 3D printing to act as plasticizers which will in turn help prolong the life of the printed object. A common issue with plasticizers like phthalate in particular is they can leach out of plastics due to their vapor pressure which leads to decreased performance and can also pose a health risk being released into its surroundings or atmosphere. A major benefit of incorporating ILs in with resins comes from their low volatility …
Factors Contributing To Diminished Long-Term Outcomes Of Secondary Infections, Alia Tayara
Factors Contributing To Diminished Long-Term Outcomes Of Secondary Infections, Alia Tayara
Honors Theses
It is widely known that patients suffer diminished long-term outcomes in the years following secondary infections, infectious diseases that occur during or after treatment of a primary infection such as influenza or COVID-19. One common secondary infection is pneumonia, which has become the most fatal hospital-acquired infection. The bacterium responsible for pneumonia is known as Pseudomonas aeruginosa. The cytotoxic supernatant in these studies was generated from a PA103 strain of Psuedomonas aeruginosa with a type III secretion system that maintains the ability to transfer exoenzymes ExoU and ExoT into target cells during infection. The focus of the following studies was …
Integrative Genome Assembly Of Staphylococcus Epidermidis And Staphylococcus Hominis Strains, Cana L. Brown
Integrative Genome Assembly Of Staphylococcus Epidermidis And Staphylococcus Hominis Strains, Cana L. Brown
Honors Theses
Due to rapid advances in sequencing technology, it is becoming increasingly easier to assemble unknown genomes from millions of short sequencing reads of nucleotides taken from the full genomic sequence (Hernandez, 2008). In this study, we used various computational programs to align reads from unsequenced strains of the bacteria Staphylococcus epidermidis and Staphylococcus hominis into a hitherto undefined, single contiguous genomic sequence. We used SPAdes to assist with template free assembly (Bankevich, 2012), BLAST to identify a suitable reference genome from closely related species (Madden, 2013), Bowtie2 to align our reads to the reference genome, SAMtools to sort and organize …
Ogt Glycosylation Of Histones In T Cells May Participate In Systemic Lupus Erythematosus, Jared Luke Ridgeway
Ogt Glycosylation Of Histones In T Cells May Participate In Systemic Lupus Erythematosus, Jared Luke Ridgeway
Honors Theses
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that primarily affects women. The etiology is not known yet, but genetics and environmental factors trigger the disease. These epigenetic changes modify gene expression and contribute to the development of the disease. It is known that T cells from patients with lupus overexpress genes that may contribute to the onset and progression of the disease. Dr. Gorelik has shown that OGT (O-linked N-acetyl-Glucosamine Transferase), which is an X-linked gene, is overexpressed in women with SLE. OGT adds b-N-acetylglucosamine (O-GlcNAc) to serine and threonine residues of proteins. …