Digital Commons Network^™

Molecular Functionalization Of Carbon Nanotubes And Use As Substrates For Neuronal Growth, Mark P. Mattson, Robert C. Haddon, Apparao M. Rao

Sanders-Brown Center on Aging Faculty Patents

A cell and substrate system and nerve regeneration implant are disclosed including a carbon nanotube and a neuron growing on the carbon nanotube. Both unfunctionalized carbon nanotubes and carbon nanotubes functionalized with a neuronal growth promoting agent may be utilized in the invention. A method is also disclosed for promoting neuronal growth.

Dual Stage Microvalue And Method Of Use, Marc J. Madou, Sylvia Daunert

Chemistry Faculty Patents

A micro-machined drug delivery device and method of use for the delivery of labile drugs is disclosed. A micro-machined sensing device and method of use is also disclosed. A micro-machined drug delivery and sensing device and method of use is additionally disclosed. All three devices are intended to be inserted into a patient's body. The drug delivery devices allow for the mixing of drug components prior to the release of the mixture into the patient's body where the mixture is labile. The micro-machined sensing device is suitable for monitoring the concentration of a specific chemical in a patient's body fluids …

Apparatus And Method For Dispersing Nano-Elements To Assemble Device, Craig A. Grimes, Elizabeth Dickey

Chemical and Materials Engineering Faculty Patents

An apparatus for dispersing a first plurality of conductive elongated nano-elements distributed within a carrier-fluid to assemble a conductive device made of a first charge-receptive area of a support surface to which at least one nano-element has attached, including: a nozzle through which the elongated nano-elements are directed such that the nano-elements pass through an electromagnetic field for imparting a preselected charge thereto, and toward at least the first charge-receptive area. The charge-receptive area is given a charge such that it attracts a first end-portion of one of the nano-elements. Also, a method of assembling a conductive device. Steps include: …

Processes For Nanomachining Using Carbon Nanotubes, Robert Ryan Vallance, Apparao M. Rao, M. Pinar Mengüç

Mechanical Engineering Faculty Patents

Novel methods and devices for nanomachining a desired pattern on a surface of a conductive workpiece are disclosed. In one aspect, the method comprises using an electron beam emitted from one or more nanotubes to evaporate nanoscale quantities of material from the workpiece surface. The surface of the workpiece to be machined may be excited to a threshold energy to reduce the amount of power required to be emitted by the nanotube. In another aspect, a device is described for nanomachining a desired pattern on a surface of a conductive workpiece, comprising a vessel capable of sustaining a vacuum, a …

Heavy Equipment Owner/Operators Dying On The Job, Kentucky Injury Prevention And Research Center

Kentucky Haz Alerts--Other

To prevent heavy equipment injuries:

• Owner/operators should become familiar with and adhere to Kentucky Occupational Safety and Health guidelines.
• Manufacturers’ procedures for operation and maintenance of heavy equipment should be followed.
• Avoid potentially hazardous situations. Operators should perform a thorough hazard assessment before work is initiated.

Propietarios/Operadores De Equipo Pesado Mueren En Su Trabajo, Kentucky Injury Prevention And Research Center

Kentucky Haz Alerts--Motor Vehicle

Para prevenir lesiones al trabajar con equipo pesado:

1. Propietarios/operadores deberán familiarizarse y aplicar las normas de Seguridad y Salud Ocupacional de Kentucky.
2. Deberán ser seguidos los procedimientos indicados por el fabricante para la operación y mantenimiento de equipo pesado.
3. Evite situaciones que impliquen un riesgo potencial. Los operadores deberán llevar a cabo una valoración cuidadosa de los riesgos potenciales antes de iniciar el trabajo.

Forage News [2003-12], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• Forage at KCA
• KFGC Awards
• 4^TH Kentucky Grazing Conference
• Characteristics Typical of Profitable Dairy Graziers in Wisconsin
• Alfalfa Average Increase
• Opportunities for Warm Season Grasses
• Costs of Maintaining a Beef Cow in Kentucky, Illinois or Michigan
• Upcoming Events

Efficient Grazing Systems: Putting Pieces Together, Charles T. Dougherty

Kentucky Grazing Conference

Pros and cons of grazing systems are well-known to this audience. Efficient grazing systems, however, are a different story. What is an efficient grazing system? I think we could argue that topic until the cows come home and I do not believe we could come to any agreement. I am going to approach the subject of efficiency from several angles but you will probably see them differently. Economic efficiencies will not be covered.

Kentucky Goat Friendly Pasture Concepts, Terry Hutchens

Kentucky Grazing Conference

Goats are accomplished grazers of grass and browse plants. In addition, they can be managed within a grazing system both intensively or extensively as long as quality forage is made available. Goats are facultative browsers, they prefer to feed at eye level and upward and then feed on forage from the top of the plant down. Goats prefer to move freely from plant to plant-removing foliage from select portions of plants. Foliage meals are dictated by quality factors that insure adequate protein and energy levels. Each stem or leaf is clipped with precision leaving the forage residue standing equal in …

Effective Use Of Pastures For Horses, Robert Coleman

Kentucky Grazing Conference

Pastures can serve two very necessary functions for the care and maintenance of horses. Not only do these areas of grasses and legumes provide a place for the horse to exercise, they can provide a significant portion of the horse’s nutrient requirement. Horses evolved as a grazing animal, so it is reasonable that many classes of horse can be adequately maintained on well-managed pastures.

The Economics Of Integrating Crop Land To Mig Grazing, Edward N. Ballard

Kentucky Grazing Conference

Illinois soils vary in their properties and producing capacities. Large areas of the state have soils that are among the most productive in the world. Other areas have soils that, because they are too steep or droughty or have some other undesirable features, are not the most productive for corn and soybeans.

However, over the past 30 years there has been a trend to place more acres in Illinois in corn and soybeans and less acres in small grains, legumes and pasture crops. Government incentive programs have encouraged more acres to be place into corn and soybean production.

Environmental Benefits With Improved Grazing, David Stipes

Kentucky Grazing Conference

The public is becoming better educated about the environment and will continually question activities that are perceived as being harmful to soil, water, air, plants, people, animals and other concerns. Livestock producers who implement well-planned grazing management systems have an excellent opportunity to compliment both production and natural resource conservation considerations. All segments of the population involved in production agriculture will be held accountable for environmental impacts that result from their operation. A proactive approach is needed by livestock and other agricultural producers to sustain the protection of the environment that is in harmony with a healthy ecosystem. All those …

Grazing Systems For Beef Cattle, John Johns

Kentucky Grazing Conference

Beef cattle represent the most important grazing livestock enterprise to Kentucky producers. As of January 1, 2003 there were 1,120,000 producing beef brood cows on 39,000 farms in the state. In addition, more than 600,000 yearling cattle are also produced. The number of total beef animals is increasing as producers put more economic reliance on beef and forage programs. In many cases, beef cattle represent the only practical method of converting high quality forage to income for producers.

Grazing Systems For Dairy, Donna M. Amaral-Phillips

Kentucky Grazing Conference

Forages which are grazed can provide anywhere from 25 to 100% of the forage consumed by growing dairy heifers, dry cows or the milking herd. In this paper, I would like to specifically deal with devising a grazing program for a dairy lactating or milking herd. Lactating dairy cows are a “high performance animal” and, as such, any decreases in the availability or quality of forage can quickly decrease milk production. Thus, the goal when designing a grazing system is to provide adequate quantities of high-quality, vegetative forage to prevent decreases in performance. These decreases in performance occur in all …

Opportunities For Warm Season Grasses, Ken Johnson

Kentucky Grazing Conference

Today I would like to do two things, first talk a little about warm season grasses, where they come from, and where they might fit in your grazing program; and second, talk about the four major native grass species and two introduced species.

Native warm season perennial grasses were an important part of the native forage species of Kentucky, supplying food and cover for deer, buffalo, and other wildlife when settlers arrived into Kentucky. With settlers plowing, overgrazing, and the introduction of other forages, Native Warm Season Grasses (NWSGs) were on the brink of extinction. These grasses included switchgrass, eastern …

Optimize Grazing--Minimize Stored Feed, Garry D. Lacefield

Kentucky Grazing Conference

The title “Optimize Grazing – Minimize Stored Feed” appears to be a bit redundant at first glance. Indeed if we optimize grazing, we will certainly minimize the amount of stored feed required to winter our animals. Putting both concepts together can serve as a reminder of the tremendous benefit of both.

Grazing represents the cheapest source of nutrients for our beef industry. Several studies have shown that the best predictor of profitability in the beef industry is cost of stored feed. In Kentucky, specifically, that means cost/amount of hay required to winter on beef animals.

Foreword And Kfgc Award Winners [2003], Garry D. Lacefield, Christi L. Forsythe

Kentucky Grazing Conference

No abstract provided.

Pharmaceutical Formulation For Poorly Water Soluble Camptothecin Analogues, Tiang-Xiang Xiang, Bradley D. Anderson

Pharmaceutical Sciences Faculty Patents

The present invention provides a general method to retard the precipitation inception time for poorly water-soluble camptothecin analogues from a supersaturated solution by a chemical conversion approach via pH alteration. This method is successfully utilized to prepare stable parenteral formulations for silatecan 7-t-butyldimethylsilyl-10-hydroxycamptothecin (DB-67), a poorly water-soluble lipophilic camptothecin analogue, in aqueous solutions containing β-cyclodextrin sulfobutyl ether (SBE-CD) or other solubilizing agents. The formulations manufactured by this method are more simple and cost-effective, of higher doses and better quality in terms of manufacture loss and formulation stability, and can be free of organic solvents (e.g., DMSO or N-methyl-2-pyrrolidinone).

Synthases, Joseph Chappell, Kathleen R. Manna, Joseph P. Noel, Courtney M. Starks

Pharmaceutical Sciences Faculty Patents

Novel synthases and the corresponding nucleic acids encoding such synthases are disclosed herein. Such synthases possess an active site pocket that includes key amino acid residues that are modified to generate desired terpenoid reaction intermediates and products. Synthase modifications are designed based on, e.g., the three-dimensional coordinates of tobacco 5-epi-aristolochene synthase, with or without a substrate bound in the active site.

Protection Against Ischemia And Reperfusion Injury, Peter R. Oeltgen, Paul D. Bishop, Mark S. Kindy, Juan A. Sanchez

Molecular and Cellular Biochemistry Faculty Patents

A compound and method for using compound-D SEQ ID NO:1 to reduce injury associated with ischemia and reperfusion of mammalian organs such as the heart. The compound may be administered as part of a preconditioning strategy which reduces the extent of injury and improves organ function following cessation and restoration of blood flow. The compound may be used in preparation for planned ischemia or in a prophylactic manner in anticipation of further ischemic events.

Method Of Solubilizing Single-Walled Carbon Nanotubes In Organic Solutions, Robert C. Haddon, Jian Chen

Chemistry Faculty Patents

Naked single-walled nanotube carbon metals and semiconductors are dissolved in various organic solutions.

Evaluation Of Foam Fractionation Column Scale-Up For Recovering Bovine Serum Albumin, Czarena L. Crofcheck, Kelly Gillette

Biosystems and Agricultural Engineering Faculty Publications

Foam fractionation is an adsorptive-bubble separation method that, according to researchers, is a feasible technique for the separation and/or concentration of proteins. The foam fractionation of bovine serum albumin (BSA) in laboratory-scale foam fractionation columns (750 and 1250 mL) and the relationship between the two laboratory-scale columns and a pilot-scale column (5000 mL) were investigated. Recovery, enrichment, and performance factor values were experimentally determined with three different column volumes with varying pore sizes, gas superficial velocities, and, in the case of the 750 mL column, foam column height. As the pore size decreased, the amount of protein recovered from the …

Temperature Control Of A Solid Substrate Cultivation Deep - Bed Reactor Using An Internal Heat Exchanger, Mari S. Chinn, Sue E. Nokes

Biosystems and Agricultural Engineering Faculty Publications

The solid substrate cultivation (SSC) process is often limited by rapid increases in temperature as a result of metabolic activity and poor heat transfer properties of the solid substrate. High temperatures can adversely affect microbial growth and product formation. Reduction of substrate temperatures is important for improved productivity, yet effective and efficient control of heat transfer in a deep-bed SSC reactor has proven difficult. An internal cooling water coil was incorporated into a deep-bed reactor system and evaluated for its ability to reduce substrate temperature. Three operating treatments were investigated: cooling water circulation whenever the center bed temperature was above …

Muriéndose Por Conducir - Colisiones Ocupacionales De Automotores En Kentucky, Kentucky Injury Prevention And Research Center

Kentucky Haz Alerts--Motor Vehicle

Para prevenir lesiones al trabajar con vehículos motorizados:

Los empleadores deben proporcionar programas de entrenamiento sobre seguridad al conducir, obligatorios y adaptados a sus empleados, que incluyan Reconocimiento de Síntomas de Distracción / Déficit de Atención del Conductor y Fatiga del Conductor.

Los empleados deben evitar distracciones y llevar siempre puesto el cinturón de seguridad.

Evite exponerse usted mismo a una situación potencialmente riesgosa. Los conductores deben siempre permanecer alerta y practicar Técnicas Defensivas de Conducción.

Dying To Drive – Occupational Motor Vehicle Collisions In Kentucky, Kentucky Injury Prevention And Research Center

Kentucky Haz Alerts--Motor Vehicle

To prevent motor vehicle injuries while working:

• Employers should provide mandatory comprehensive employee driver safety training programs including recognition of symptoms of driver distraction/inattention and driver fatigue.
• Employees should avoid distractions and wear seat belts at all times.
• Don’t place yourself in a potentially hazardous situation. Drivers should always stay alert and practice defensive driving techniques.

Forage News [2003-11], Department Of Plant And Soil Sciences, University Of Kentucky

Forage News

• 4^TH Kentucky Grazing Conference in Lexington
• Buttercup Control in Cool-Season Grass Pastures
• Does “Endophyte” in Stockpiled Tall Fescue Impact Animal Performance?
• Upcoming Events

Content And Criterion Validity Evaluation Of National Public Health Performance Standards Measurement Instruments., Joyce Beaulieu, F. Douglas Scutchfield, Ann V. Kelly

Preventive Medicine and Environmental Health Faculty Publications

OBJECTIVE: The Centers for Disease Control and Prevention's National Public Health Performance Standards Program (NPHPSP) has developed instruments to measure the performance of local and state public health departments on the 10 "Essential Services of Public Health," which have been tested in several states. This article is a report of the evaluation of the content and criterion validity of the local public health performance assessment instrument, and the content validity of the state public health performance assessment instrument.

METHODS: Health department performance is measured using a set of indicators developed for the 10 Essential Services of Public Health and a …

Temperature, Stress, And Corrosive Sensing Apparatus Utilizing Harmonic Response Of Magnetically Soft Sensor Element (S), Craig A. Grimes, Keat Ghee Ong

Chemical and Materials Engineering Faculty Patents

A temperature sensing apparatus including a sensor element made of a magnetically soft material operatively arranged within a first and second time-varying interrogation magnetic field, the first time-varying magnetic field being generated at a frequency higher than that for the second magnetic field. A receiver, remote from the sensor element, is engaged to measure intensity of electromagnetic emissions from the sensor element to identify a relative maximum amplitude value for each of a plurality of higher-order harmonic frequency amplitudes so measured. A unit then determines a value for temperature (or other parameter of interst) using the relative maximum harmonic amplitude …

Hispanic Laborer Dies From Fall Off Roof, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Falls

On March 3, 2003, a 22-year-old Hispanic female laborer (decedent) died when she fell from a roof. She had been working on the roof with her brother, who was a sub-contractor for a local roofing company. The work crew consisted of two brothers and the decedent. Two days prior to the incident, the decedent had worked for her brother cleaning and organizing materials on the ground at another location. It was the decedent’s first day on this job site. It is unknown whether or not the decedent had worked on other roofing jobs. Her job was to organize materials and …

Beyond The Shelf: Serving Historic Kentuckiana Through Digital Access [October 2003], Becky Ryder, Eric Weig, Kopana Terry, Peter Hesseldenz

Library Presentations

No abstract provided.