Digital Commons Network^™

Inadequate Physician Knowledge Of The Effects Of Diet On Blood Lipids And Lipoproteins., Mary M. Flynn, Chris N. Sciamanna, Kevin C. Vigilante

College of Population Health Faculty Papers

BACKGROUND:To assess the nutrition knowledge of physicians on the basic effects of diet on blood lipids and lipoproteins.

METHODS:Anonymous mailed dietary knowledge surveys to 6000 randomly selected physicians in the United States licensed in either Internal Medicine or Cardiology.RESULTS:Response rate: 16% (n = 639). Half of the physicians did not know that canola oil and 26% did not know olive oil were good sources of monounsaturated fat. Ninety-three percent (84% of cardiologists vs. 96% of internists; p < 0.001) did not know that a low-fat diet, in general, would increase blood triglycerides. Approximately three-quarters (70% of cardiologists vs. 77% of internists; p < 0.01) did not know a low-fat diet would decrease HDL-c and almost half (45%) thought that a low-fat diet would not change HDL-c.

CONCLUSIONS:If physicians are to implement dietary and cholesterol management guidelines, they will likely need to become more knowledgeable about nutrition.

Jefferson Alumni Bulletin – Volume 53, Number 1, December 2003

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 53, Number 1, December 2003 The Dean’s Column by Thomas J. Nasca ’75, Page 4 Early Anesthesia Research and Jeffersonians, Page 6 Grunwald Appointed Chair of Anesthesiology, Page 7 Marone Honored for His Involvement in Establishing the Spinal Cord Injury Center, Page 8 Alumni Are Involved in the Search for the Next University President, Page 9 The Fortunate Beneficiaries of Our Education, by Richard Wenzel ’65, Alumni Achievement Award Winner, Page 14 Reunions, Clinic Talks, the Alumni Banquet, Pages 15–32

Science-Technology Division, James Manasco

Sci-Tech News

No abstract provided.

New Science And Technology Journals, Earl Mounts

Sci-Tech News

No abstract provided.

Embryonic Origins Of A Motor System: Motor Dendrites Form A Myotopic Map In Drosophila, Matthias Landgraf, Victoria Jeffrey, Miki Fujioka, James B. Jaynes, Michael Bate

Department of Biochemistry and Molecular Biology Faculty Papers

The organisational principles of locomotor networks are less well understood than those of many sensory systems, where in-growing axon terminals form a central map of peripheral characteristics. Using the neuromuscular system of the Drosophila embryo as a model and retrograde tracing and genetic methods, we have uncovered principles underlying the organisation of the motor system. We find that dendritic arbors of motor neurons, rather than their cell bodies, are partitioned into domains to form a myotopic map, which represents centrally the distribution of body wall muscles peripherally. While muscles are segmental, the myotopic map is parasegmental in organisation. It forms …

Overview, David B. Nash

College of Population Health Faculty Papers

No abstract available.

Transcriptional Inhibition Of Type I Collagen Gene Expression In Scleroderma Fibroblasts By The Antineoplastic Drug Ecteinascidin 743., Natalia Louneva, Biagio Saitta, David J Herrick, Sergio A. Jimenez

Department of Medicine Faculty Papers

We previously showed that COL1A1 expression is up-regulated at the transcriptional level in systemic sclerosis (SSc) fibroblasts and that the CCAAT-binding factor (CBF) is involved in this increased expression. Ecteinascidin 743 (ET-743) is a chemotherapeutic agent that binds with sequence specificity to the minor groove of DNA and inhibits CBF-mediated transcriptional activation of numerous genes. Therefore, we examined the effects of ET-743 on the increased COL1A1 expression in SSc fibroblasts. The drug caused a potent and dose-dependent inhibition of type I collagen biosynthesis, which reached 70-90% at 700 pM without affecting cell viability. The same drug concentration caused 60-80% reduction …

Nurses Alumni Association Bulletin, Fall 2003, Paula Levine, Elizabeth K. Prisnock, Sally H. Wagner, John J. Wagner

Nursing Alumni Bulletins

2003 - 2004 Meeting Date Calendar

2004 Annual Luncheon & Meeting Notice

Officers, Committee Chairs, Satellite and Volunteers

Bulletin Publication Committee

The President's Message

Treasurer's Report

Resume of Minutes

Clinical Nursing Practice And Patient Outcomes Endowed Fund

JMC Appreciation Award 1978

Office News

Committee Reports

• Relief Trust Fund
• Satellite - Harrisburg Satellite Area
• Scholarship
• Social
• Nominating
• Bulletin
• Development

Annual Giving

News About Graduates

Memories

Odds & Ends

Janet C. Hindson Award Recipients and Nominees

Janet C. Hindson Award Qualifications

Happy Birthday, To Be 80 or more

In Memoriam, Names of Deceased Graduates

50th Anniversary Class

Luncheon Attendees

Center page

Class …

Il-7 Enhances Peripheral T Cell Reconstitution After Allogeneic Hematopoietic Stem Cell Transplantation., Onder Alpdogan, Stephanie J Muriglan, Jeffrey M Eng, Lucy M Willis, Andrew S Greenberg, Barry J Kappel, Marcel R M Van Den Brink

Department of Medical Oncology Faculty Papers

We used clinically relevant murine allogeneic bone marrow transplantation (BMT) models to study the mechanisms by which IL-7 administration can improve posttransplant peripheral T cell reconstitution. After transplant we could distinguish two populations of mature donor T cells: (a) alloreactive T cells with decreased expression of CD127 (IL-7 receptor alpha chain) and (b) nonalloreactive T cells, which express CD127 and undergo homeostatic proliferation. IL-7 administration increased the homeostatic proliferation of nonalloreactive T cells, but had no effect on alloreactive T cells and the development of graft-versus-host disease. Allogeneic transplant of purified hematopoietic stem cells and adoptive transfer of thymocytes into …

Aisr Connections, Fall 2003 (2003-2004 Orientation Issue)

The AC's Research Support Newsletter (Formerly AISR Connections)

No abstract provided.

Jefferson Alumni Bulletin – Volume 52, Number 4, September 2003

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 52, Number 4, September 2003 The Dean's Column by Thomas J. Nasca ’75, page 4 The Orbit of My Eye an essay by Risa Ravitz ’05, page 8 Students Teach Underserved Children to Read, in Addition to Providing Medical Care for the Parents, page 10 Combining Two Types of Radiation Therapy to Improve the Treatment of Brain Cancer, page 17 Landmark Study of Early Surgery for Epilepsy, page 17 Research on How to Improve Physician Empathy , page 18 Using Plants to Produce Antibodies Against Rabies, page 19 HIV's Escape Route from Drugs and Vaccines …

Global Partnerships To Strengthen The Evidence Base For Nursing, Beth Ann Swan Phd, Crnp, Naeema H. Al-Gasseer Phd, Rn, Norma M. Lang Phd, Rn, Faan, Frcn

College of Nursing Faculty Papers & Presentations

There is a growing emphasis on building the evidence base as governments, health systems, practitioners, and consumers, nationally and globally, search for ways to improve health care outcomes and enhance the efficiency and effectiveness of health services.

Nurses and midwives constitute the largest group of health service providers in the majority of health systems around the globe.

The WHO Global Advisory Group on Nursing and Midwifery recommended that WHO should form strategic alliances with partners to identify uniform core indicators and build a solid body of evidence to inform national health policies, particularly in the area of cost-effective nursing and …

Science-Technology Division, James Manasco

Sci-Tech News

No abstract provided.

New Science And Technology Journals, Earl Mounts

Sci-Tech News

No abstract provided.

Organizational Characteristics And Restraint Use For Hospitalized Nursing Home Residents., Meg Bourbonniere, Neville E. Strumpf, Lois K. Evans, Greg Maislin

College of Nursing Faculty Papers & Presentations

OBJECTIVES: To examine the effect of organizational characteristics on physical restraint use for hospitalized nursing home residents.

DESIGN: Secondary analysis of data obtained between 1994 to 1997 in a prospective phase lag design experiment using an advanced practice nurse (APN) intervention aimed at reducing physical restraint for a group of hospitalized nursing home residents.

SETTING: Eleven medical and surgical units in one 600-bed teaching hospital.

PARTICIPANTS: One hundred seventy-four nursing home residents aged 61 to 100, hospitalized for a total of 1,085 days.

MEASUREMENTS: Physical restraint use, APN intervention, age, perceived fall risk, behavioral phenomena, perceived treatment interference, mental state, …

Characterization Of Mutations And Loss Of Heterozygosity Of P53 And K-Ras2 In Pancreatic Cancer Cell Lines By Immobilized Polymerase Chain Reaction, James Butz, Eric Wickstrom, Jeremy Edwards

Department of Biochemistry and Molecular Biology Faculty Papers

Background

The identification of known mutations in a cell population is important for clinical applications and basic cancer research. In this work an immobilized form of the polymerase chain reaction, referred to as polony technology, was used to detect mutations as well as gene deletions, resulting in loss of heterozygosity (LOH), in cancer cell lines. Specifically, the mutational hotspots in p53, namely codons 175, 245, 248, 249, 273, and 282, and K-ras2, codons 12, 13 and 61, were genotyped in the pancreatic cell line, Panc-1. In addition LOH analysis was also performed for these same two genes in Panc-1 by …

Children With Disturbances In Sensory Processing: A Pilot Study Examining The Role Of The Parasympathetic Nervous System., Roseann C. Schaaf, Lucy Jane Miller, Duncan Seawell, Shannon O'Keefe

Department of Occupational Therapy Faculty Papers

This study was a preliminary investigation of parasympathetic nervous system (PNS) functioning in children with disturbances in sensory processing. The specific aims of this study were to (1) provide preliminary data about group differences in parasympathetic functions, as measured by the vagal tone index, between children with disturbances in sensory processing and those without; (2) determine effect size and power needed for future studies; and (3) to lay the foundation for further examination of the relations of parasympathetic functioning and functional behavior in children with disturbances in sensory processing. Participants were 15 children, nine with disturbances in sensory processing and …

An Operational Measure Of Physician Lifelong Learning: Its Development, Components And Preliminary Psychometric Data, Mohammadreza Hojat, Thomas J. Nasca, James B. Erdmann, Anthony J. Frisby, Jon J. Veloski, Joseph S. Gonnella

Academic Commons and Scott Memorial Library Staff Papers and Presentations

Despite the emphasis placed on physicians’ lifelong learning, no psychometrically sound instrument has been developed to provide an operational measure of the concept and its components among physicians. The authors designed this study to develop a tool for measuring physician lifelong learning, to identify its underlying components and to assess its psychometric properties. A 37-item questionnaire was developed, based on a review of literature and the results of two pilot studies. Psychometric analyses of the responses of 160 physicians identified 19 items that were included in the Jefferson Scale of Physician Lifelong Learning. Factor analysis of the 19 items showed …

Using Computer-Based Case Studies For Developing Information Searching Skills And Implementing Evidence-Based Medicine In Patient Care Plans., Anthony J. Frisby, Daniel G. Kipnis

Academic Commons and Scott Memorial Library Staff Papers and Presentations

Since 1987 over 1,300 first year medical students at Jefferson Medical College in Philadelphia, PA have completed a required Medical Informatics course. This course is the responsibility of the Library’s Education Services division. Designed to develop information-searching skills and teach methods for evaluating evidence-based medicine, the course employs a combination of self-paced online tutorials and case studies. The case studies in particular have proven to be a very effective learning tool. Course evaluations are consistently positive, with comments citing the interesting case studies and the effectiveness and appropriateness of the teaching method. This chapter describes the case development process, presents …

Annual Report, 2003, Edward Tawyea

Annual Reports & Administrative Documents

No abstract provided.

2003 Commencement For Jefferson Medical College And College Of Graduate Studies

Sidney Kimmel Medical College Commencements

No abstract provided.

2003 Commencement For Jefferson Medical College And College Of Graduate Studies

Jefferson College of Biomedical Sciences Commencement

No abstract provided.

Class Day To Honor The Class Of 2003

Sidney Kimmel Medical College Class Day

The Class Day program includes a list of speakers, awards given, officers of the graduating class, student council, and Clinic editors.

Filling The Gaps In Physician Communication. The Role Of The Internet Among Primary Care Patients, Chris N. Sciamanna, Melissa Clark, Joseph Diaz, Stephanie Newton

College of Population Health Faculty Papers

BACKGROUND:

Millions of people use the Internet as a source for health information yet little is understood about how the use of the Internet for health information is related to the doctor-patient relationship.

OBJECTIVE:

We conducted the present study to understand the association between one’s interest in using the Internet for general and quality-oriented health information and attitudes about one’s communications with health care provider(s).

DESIGN:

Cross-sectional survey.

SETTING:

Four community-based primary care practices in Rhode Island.

MEASUREMENTS:

A single self-administered survey included items to measure: interest in using the Internet to look for general and quality-oriented information and a …

Care Management For Persistent Pain: An Introduction, Christine W. Hartmann, Neil I. Goldfarb, Susan S. Kim, Bhaskar R. Nuthulaganti, Raafat Seifeldin

College of Population Health Faculty Papers

Persistent pain is a frequently occurring condition with significant economic, clinical, and humanistic implications, for both individuals and society. Current literature, however, points to unresolved issues with regard to its identification, assessment, diagnosis, and treatment, and a number of suggestions have been made for improving the quality of care for pain sufferers. Because persistent pain shares many of the salient features of other chronic conditions such as diabetes and congestive heart failure, it is reasonable to believe that the adoption of a coordinated approach to care management could substantially improve the quality of care. Several strategiesincluding identification, appropriate referral, education, …

Jefferson Alumni Bulletin – Volume 52, Number 3, June 2003

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume 52, Number 3, June 2003 Dean's Column by Dean Thomas J. Nasca ’75, page 4 Update on Transplant Surgery, page 5 The New Jefferson Hospital for Neuroscience and Farber Institute for Neurosciences, page 6 Researchers Show That Human Neural Stem Cells Can Become Dopamine-Making Brain Cells in the Lab, page 8 Evidence of Greater Sensitivity to Addictive Drugs in Adolescence, page 8 New Hope for Patients with Late Stage Parkinson's, page 10 Above and Beyond the Call: Three Alumni Heroes, page 11 The Mother in The Gross Clinic: A Medical Explanation of Her Hand, page …

Systemic Sclerosis: Current Views Of Its Pathogenesis., Chris T. Derk, Sergio A. Jimenez

Department of Medicine Faculty Papers

Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities. Clinically, SSc is very heterogeneous, encompassing a spectrum ranging from mild limited forms of skin sclerosis with minimal internal organ involvement to severe skin and multiple internal organ fibrosis. Mortality and morbidity in SSc are very high and are directly related to the extent of the fibrotic and microvascular alterations. A better understanding of the pathogenesis of this incurable disorder will help to better target and design effective …

2003 Commencement For College Of Health Professions

Jefferson College of Nursing Commencements

No abstract provided.

2003 Commencement For College Of Health Professions

Jefferson College of Health Professions and Jefferson College of Pharmacy

No abstract provided.

European Mistletoe/Iscador® Faq , Clinic Staff

Topics in Integrative Medicine

Mistletoe (Viscum album) may be the most commonly used complementary cancer therapy in Europe today. Background information and important questions are presented.