Digital Commons Network^™

A Comparison Of How The United States And England Educators Teach Reading, Katy Wood

Honors Theses

During my time of studying to be an early childhood education teacher at Ouachita Baptist University, I felt a calling to explore and become immersed in another culture. I had never been out of the country before, and I believed that in order to become a well-rounded teacher, I needed to learn how other countries' teachers taught their children. I chose to study abroad in Liverpool, England, at Liverpool Hope University. I took several classes at the university, but one of the most impactful things that I did while I was in England was observing in St. Leo's and Southmead …

Identification Of Bacterial Species Using Colony Pcr, Kaiti Walker

Honors Theses

My research consisted of two separate parts, both involving the PCR methods. In part one I was trying to identify bacteria isolated from a chicken coop. In part two I was trying to identify bacteria isolated from the bluff. In both parts, I used a technique called colony PCR. This concept uses a single colony of bacteria to complete the PCR reaction. One pipet tip from a single colony is selected from the plate and mixed into a tube containing ultrapure water. A small amount of this bacterial mixture is then added into the PCR reaction. In the first part …

Understanding A Possible Wonder Drug: A Radial Diffusion Assay For The Rapid Evaluation Of Antimicrobial Peptides, Dustin Walter

Honors Theses

Antimicrobial peptides (AMPs) have been a major research focus due to their potential to combat a variety of human pathogens. Our laboratory has identified several novel peptides that display significant antifungal activity. The effectiveness of these peptides in vitro has been promising; however, it has been shown that physiological concentrations of various salts along with other conditions are inhibitory to peptide activity. To further explore the inhibitory effects of these salts, a new assay was developed whereby we can observe the effects of various salts on the peptide killing activity. For our studies, we employed several clinical isolates of Candida …

The Efficacy Of Emdr: A Meta-Analysis Of Emdr As Clinical Treatment, Allison Smith

Honors Theses

Eye movement desensitization and reprocessing (EMDR) is a controversial clinical treatment most often used in the treatment of anxiety and depressive disorders. Many clinicians use this therapy, but no consensus exists whether this treatment works. This meta-analytic review examined EMDR versus waitlist or alternative treatments, in adult and child populations, and in reduction of depression and anxiety symptoms. Results indicate that EMDR has no significant effect in the reduction of symptoms in either population for either psychological disorder. Implications for further research are discussed.

Toward An Islamic Modernity: Ataturk, Erdogan, & Gulen, Kevin Jackson

Honors Theses

The Gülenist movement, also known as Hizmet, is an Islamic reform movement that has arisen recently in Turkey. Centered on the teachings of Fethullah Gülen, an Islamic scholar and teacher, the movement has been the focus of both praise and controversy. Accused of being a dangerous “state within a state” by the Turkish government, it has nevertheless attracted a wide following in Turkey and seeks a global audience. In Hizmet, Fethullah Gülen has developed a movement that offers to reconcile the tensions between Islam and Western modernity, encouraging its followers to keep the Islamic faith while embracing the challenges and …

Acute Promyelocytic Leukemia As A Possible Source For Ajulemic Acid Binding, Brian Christopher Monk

Honors Theses

Acute promyelocytic leukemia (APL) is a cancer that affects bone marrow, the blood-forming tissue (of the body). This type of leukemia accounts for approximately 10% of acute myeloid leukemia (AML) cases. Normally this cancer is treated with a drug called all-trans retinoic acid (ATRA), but other variations of treatment do exist. The importance of this research is that APL cells express contains a receptor, retinoic acid receptor-a (RARa), which ajulemic acid (AJA) may bind to in order to induce apoptosis in Ewing sarcoma (ES), a pediatric bone cancer. Therefore, this research will focus on the ability of AJA to induce …

The Effect Of Cannabinoids On Triple Negative Breast Cancer Cells, Haley Dahl

Honors Theses

Triple Negative Breast Cancer (TNBC) is a difficult type of cancer to treat because it is negative for progesterone, estrogen, and HER-2 receptors. Because TNBC is negative for these three receptors, it does not respond to normal hormonal therapies. The purpose of my experiment is to see if different cannabinoids, compounds from the cannabis plants, could be used as alternative treatment options. These experiments employed three different cannabinoids: ajulemic acid, cannabidiol, and hemp oil. Cell viability was measured after 72 hours of treatment using a MTT assay. The results showed that the three cannabinoids could be used to effectively destroy …

Expression Analysis Of A Glucose Oxidase Transgene In Tobacco, Jordan Burt

Honors Theses

Glucose oxidase (GOX) is an enzyme in plants that catalyzes the oxidation of glucose to hydrogen peroxide and Glucono delta-lactone[5]. We have expressed GOX under the control of an estrogen inducible system, XVE, to analyze the gene's expression under this system compared to a system using the 35s system. The 35s system contains a promoter that constitutively turns on the GOX gene in the Nicotiana tabacum plant which causes the gene to always be turned on. Leaf disc assays were performed with discs from 35s, XVE, and also wild type plants (not containing the GOX gene) in order to extract …

Brands Crossing Borders: Cross-Cultural Issues In Brand Localization In And From China, Molly Catherine Bowman

Honors Theses

As China continues to play a more integral role in the global economy, the ability to do business in, with, and from China is of the utmost importance. With the country's nascent transformation from a manufacturing economy to a value-added hub of innovation, Chinese companies face new challenges in communicating their brands and values abroad, and their Western counterparts face equal if not greater challenges in maintaining their market share on a global scale.

Communication will be the key to success in this dynamic environment. This paper will explore some of the unique China stories of prominent global organizations-- how …

Ten Weeks With Green Beans...And Then Some: Determination Of Bisphenol-A (Bpa) In Canned Goods From Arkansas Markets Using Fluorescence Spectrophotometry, Rachel Pruett

Honors Theses

Bisphenol A (BPA) is a chemical widely used in production of consumer goods. It has come under scrutiny recently after being labeled as an endocrine disruptor (ED), mostly causing adverse effects in infants and young children. It has been associated with diabetes, cardiovascular disease, and abnormal maturation. Because it is so commonly used in product development, humans are exposed to BPA through various means, such as ingestion or dermal absorption. It is a concern that the combined exposure could cause serious effects even in small doses.

In canned foods, the chemical is made into an epoxy resin to provide a …

Handedness: Does It Matter?, Jessie Little

Honors Theses

Pharmaceutical drugs are activated through a process called xenobiotic metabolism. Out of the drugs on the market, 50% are chiral, having two enantiomers. When this drug is metabolized, one of the enantiomers is typically preferred over the other. This unique specificity is thought to be a result of the structure of the protein. Interactions between different residues and the drug being metabolized may affect the movement and orientation of the drug as it moves down the channel of the protein to be oxidized. Further understanding of the metabolism of chiral drugs could possibly be used to predict how new drugs …

Thrilling Monotony: A Summer Of Alzheimer's Research, Baronger Dowell Bieger

Honors Theses

The primary genetic risk determinant for late-onset Alzheimer's disease is the apolipoprotein E gene (APOE). Variations in this gene produce three different isoforms of the apolipoprotein E protein (ApoE): ApoE2, ApoE3, and ApoE4. ApoE# is the most common isoform, so rates of LOAD among other genotypes are indexed to this variant. ApoE2 is rather rare, but its carriers are less likely to get LOAD; when they do, they get it later. The second most common variant is ApoE4, and its carriers are significantly more likely to get LOAD. They also tend to succumb earlier. Once developed, LOAD is characterized by …

Studying The Effects Of Theraflu On The Growth Of Selenastrum Capricornutum, Hannah Gray Boren

Honors Theses

Algae contribute to self-purification of streams and rivers and are necessary as food for fish and as components of aquatic food webs (1). However, too much or too little algae may create or be indicative of a problem. If nutrients are present in large amounts, algae growth may become excessive, resulting in algal “blooms.” These algal blooms can change the chemistry of the water, making it toxic to other aquatic occupants, including fish, birds, animals, and other plants (1). On the other hand, if nutrients in the water are limiting or are exhausted, algae growth is inhibited, which results in …

Content And Character: Modeling Christian Communication After Jesus' Sermon On The Mount, Sophie Demuth

Honors Theses

In order to learn about Jesus’ communication method, I decided to study the Sermon on the Mount. After doing an in-depth study of Jesus’ method (how he taught, the devices he used, and his structure), I realized his method is only a part of his effectiveness as a speaker. Without credibility and integrity as well, Jesus’ teaching would fall flat and cease to have authority. This realization especially struck me because, in the field of communications, method is emphasized over integrity and character. I decided to compare Jesus’ method and character with what the communication field teaches about public speaking. …

Uncovering The Truth About Argentina's Dirty War, Macy Fouse

Honors Theses

Major historical events that blatantly defy human rights are typically common knowledge and recognized by most historians. For instance, everyone knows about the Holocaust. Even smaller-scale massacres, like Tiananmen Square, are included in most history textbooks. The Dirty War of Argentina, a brutal seven-year ordeal that violated the basic human rights of thousands of people, is not usually an era discussed by history textbooks. The society of Argentina is still healing from the effects of this war, but how can they be expected to heal when history will not even acknowledge their past or their pain?

While commonly referred to …

Beauty Is Born Of The Rain: Walter Inglis Anderson's Art And Isolation, Chloe Evelyn Huff

Honors Theses

Walter “Bob” Inglis Anderson: naturist, painter, and ceramicist. Some say he was mad, while others were inclined to say that he was merely passionate regarding nature and his watercolors. However, he is highly regarded as one of the most talented artists east of the Mississippi. In the following pages, his life, art, and battles with a mental illness will be spread out and investigated closely with the primary goal of observing whether his bouts of illness affected his art. To investigate this relationship, it is necessary to examine Walter Anderson’s early life and art, along with his progression into mental …

Interaction Of Disease, Drugs, And Disposition In Ewing's Sarcoma Patients, Madeline Martin

Honors Theses

Ewing's Sarcoma is a pediatric bone cancer that is highly aggressive, leading to a five year survival rate of not only 30% even with multi-modal treatment protocols. Improved therapeutic options are desperately needed. Our research has focused on the ability of the psychoactive cannabinoid, ajulemic acid, to induce apoptosis and decrease metastatic potential in cells from members of the Ewing Sarcoma family of tumors. Recently, we explored the effects of the naturally-occuring cannabinoid, cannabidiol, on three-dimensional spheroids that mimic the cellular components and microenvironment of Ewing's tumors. We looked at how this treatment affects VEGF, a mediator of angiogenesis, to …

Gap Closure To Complete The Genome Assembly For Staphylococcus Agnetis, Joseph A. Koon Ii

Honors Theses

Poultry lameness is a significant problem resulting in millions of dollars in lost revenue annually. In commercial broilers, the most common cause of lameness is bacterial chondronecrosis with osteomyelitis (BCO). The majority of BCO infections involve Staphylococcus agnetis, a bacterium previously not isolated from poultry. Administrating S. agnetis in drinking water to broilers reared on wire flooring increased the incidence of BCO three-fold when compared with broilers drinking tap water (P= 0.001). We are completing an assembly of the sequence of the S. agnetis genome. Currently, the assembly is in 2 large contigs of 2491 kbp and 38 kbp, and …

Dissolving The Conflict: Why The Church Should Be More Open To Evolution, Kyle Hargis

Honors Theses

Evolution can be very controversial, but I don't think that this needs to be the case. Having grown up in the south, in a Southern Baptist Church, I saw that evolution was always viewed as anti-theistic and treated like a trick from the devil. Many of the people that I went to church with believed that the world was only six thousand years old and would defend that opinion wholeheartedly, but my parents taught us that the world was very old. They were not strictly evolutionists but they believed that it very well could have happened if God chose to …

Bringing Bpa To Light: Determination Of Bisphenol A In Thermal Receipt Paper Water Samples And Lake Water Samples Using Fluorescence Spectrophotometry, Bailey Chitwood

Honors Theses

Bisphenol A (BPA) is a chemical that is commonly used in harder plastic products, in the lining of food cans, and in thermal receipt paper. The usage of BPA in common products has become a concern for humans, especially for infants and young children, because of its effects as an endocrine disrupter. BPA has been linked to diabetes, cardiovascular disease, obesity, and certain developmental disorders. Because of the possible effects of BPA on the development of infants and young children, the use of BPA in baby bottles and other baby products has been outlawed. However, BPA is still used in …

Natural Language Processing For Foreign Language Learning, Jacob Kausler

Honors Theses

This research presents novel algorithms which generate sentences in a natural language, using natural language generation techniques. The purpose of the algorithms is to benefit foreign language learning. As far as we can tell, ours is the first such research being done in the field. In creating the algorithms, we also developed a piece of software to showcase the work and allow testing by users. The main algorithm begins by generating sentence models by using one of two methods, namely modeled sentence generation and semantic sentence generation. Each of these have benefits and drawbacks, which the user must take into …