Digital Commons Network^™

Effects Of Life-Extending Compounds On Body Composition In Long-Lived Growth Hormone Receptor Antagonist Mice, Matthew Kirstein

Student Research and Creative Activity Expo

Early body composition responses to longevity-promoting dietary interventions in long-lived growth hormone receptor antagonist (GHA) mice reveal significant treatment-associated physiological differences, with ongoing studies evaluating their relevance to long-term survival and overall functional aging outcomes.

Effects Of Developmental Temperature On Neuron Density In Key Regions Of The Female Xiphophorus Multilineatus Brain​, Jocelyn Newton, Emma Wanat

Student Research and Creative Activity Expo

To determine whether developmental temperatures shape the neuronal composition underlying mate choice, we quantified neuron density across key brain regions in X. multilineatus females reared in high- and low-temperature environments.

Quantifying Iron Recycling In The Nutrient-Rich North Atlantic Ocean, Adam Jackvony

OneUSF Summer Undergraduate Research Symposium

The North Atlantic is a volatile region with low iron availability, where diatoms make up a majority of the phytoplankton. Due to iron’s low supply and high demand, it is often retained within the system and reused through iron recycling. Iron recycling helps predict fluctuations in diatom biomass, which directly impacts the biological carbon pump, transporting carbon dioxide from the atmosphere into the deep ocean. Estimating recycling rate allows for comparisons to other regions that have previously been studied creating a better understanding of the ocean-climate system and how different environmental factors influence the climate. Using assumed source water iron …

Pyrodinium Bahamense Environmental Growth: A Study Of How Local Salinities Affect P. Bahamense Growth And Toxicity, Elsa M. Kusek, Valentina Arnold Villarreal

OneUSF Summer Undergraduate Research Symposium

The Steidinger Scholar Internship at the Florida Fish and Wildlife Research Institute provides a unique and valuable research experience for undergraduate students through experiential learning. Over the summer of 2026, we’re integral team members of the Harmful Algal Blooms Biotoxins Team, helping to monitor the presence of Pyrodinium bahamense, a saxitoxin producing dinoflagellate, and its associated toxins in scallop tissues throughout the Pasco County Recreational Scalloping Zone. This monitoring is crucial to protecting human health, preserving Florida's resources, and informing management decisions. To further our understanding of P. bahamense, we explored the impact of salinity on growth, pH, stress, and …

Optimizing Silk Fibroin–Polyethylene Oxide Polymer Blends For Electrospun Nanofibrous Scaffold Fabrication, Lucas Niemas

OneUSF Summer Undergraduate Research Symposium

Cardiovascular disease remains a major cause of morbidity and mortality, often requiring surgical repair or replacement of damaged tissues. Current cardiovascular substitutes, including synthetic grafts, mechanical valve replacements, and biologically derived tissues, have improved patient outcomes but still face limitations such as thrombosis risk, limited remodeling capacity, mechanical mismatch, and durability concerns. Cardiovascular tissue engineering seeks to address these challenges by developing biomimetic scaffolds that support cell attachment, extracellular matrix synthesis, tissue integration, and in vivo adaptation. Silk fibroin is a promising natural biomaterial because of its biocompatibility, tunable degradation, favorable mechanical properties, and anti-inflammatory potential; however, its low solution …

Protocol For Nod Islet Isolation Using A Novel Two-Filter Purification System, Sama Nayakanti

OneUSF Summer Undergraduate Research Symposium

Type 1 Diabetes (T1D) is an autoimmune disease characterized by the inflammation and destruction of pancreatic islets by infiltrating immune cells. As T1D incidence continues to surge worldwide, it is necessary to develop therapies capable of strengthening and protecting islet function.

Our prior research has previously demonstrated the protective antioxidant effects of Cornus officinalis (CO), a medicinal herb with known anti-diabetes properties, using 1.1B4 and NIT-1 transformed pancreatic β-cell lines. Although these cell lines are valuable and cost-efficient β-cell models, they are not fully representative of primary β-cell biology, which may affect their antioxidant response to CO.

To this end, …

Chemical Effects Of Microplastics On Photochemistry In A Coral-Associated Zooxanthella, Meghan A. Hennings, Matz Indergard, John E. Parkinson

OneUSF Summer Undergraduate Research Symposium

Coral bleaching is the process by which corals lose their symbiotic microalgae in response to stressful conditions. These photosymbionts, known as zooxanthellae, give corals their color and sustain host growth through mutualistic nutritional exchange. Bleaching events are becoming more common and severe, driving research into coral conservation and the resilience of each partner in the symbiosis. Yet it is unknown how certain pollutants, such as microplastics, may affect bleaching outcomes. Previous research in our laboratory has demonstrated that the presence of polyvinyl chloride (PVC) microplastics inhibits bleaching recovery in sea anemones (a coral model), but it remains unclear whether the …

Investigation Of Antimicrobial Properties In Bacteria Of Loggerhead Turtle (Caretta Caretta) Nesting Beaches, Norah P. Nunez

OneUSF Undergraduate Research Conference

Loggerhead sea turtles (Caretta caretta) are considered threatened under the Endangered Species Act. Identifying bacteria of Loggerhead turtle nesting beaches can shed light on antimicrobial properties of agents that could impact turtle hatchling survival. Bacteria from beaches in Fort de Soto and Lido Key were isolated and analyzed for antimicrobial properties, as these beaches are commonly Loggerhead nesting sites. Isolates were chosen for apparent inhibition of bacterial growth then tested against medically significant bacteria in two rounds of modified Kirby-Bauer. The identities of the bacteria were investigated through a series of differential and selective tests and confirmed with …

Gopher Tortoise Burrow Census And Population Estimate In The University Of South Florida Sarasota-Manatee Conservation Area, Anthony J. Richard, Linda Vesser

OneUSF Undergraduate Research Conference

The gopher tortoise (Gopherus polyphemus) is a threatened species in Florida, and both the tortoise and its burrow are protected in their range across the southeastern United States.  The University of South Florida Sarasota-Manatee (USFSM) campus is home to a 6.6-acre conservation area that supports a population of gopher tortoises as well as other native and threatened plant and animal species. As an initial determination of population size, we mapped all current burrow locations using a Garmin GPSMAP 64st.  As tortoises spend most of their time inside their burrows, estimates of population size can be difficult.  However, burrow surveys are …

The Invasive Black Spiny-Tailed Iguana (Ctenosaura Similis): Insights From Diet, Parasites, And Genetics, Spence Gerber, Andre Aquino, Valentin Basarevskij, Abigail Pal

OneUSF Undergraduate Research Conference

The Black Spiny-tailed Iguana (Ctenosaura similis), native to Mexico and Central America, is invasive to Florida following its introduction in the 1980s. Research on C. similis integrates anatomical examination, parasite identification, genetic characterization, and gut content analysis to better understand its ecological impact. Specimens culled by authorized agencies were utilized as a source of otherwise unused biological samples. To date, nearly 30 carcasses have been dissected, yielding data on diet and endoparasite fauna as well as providing insight into the species’ potential effects on native ecosystems through resource competition and predation. Although their identification has been problematic, a …

Circadian Regulation Of Viral Replication And Immune Responses: Implications For Covid-19 And Other Viral Infections, Carolina Santa Cruz, Saanvi Dhala, Raneen Daoud, Arianna Skevington-Olivera, Ruhani Dashmesh, Arjun Tummala

OneUSF Undergraduate Research Conference

Circadian rhythms are 24-hour biological cycles regulating sleep, metabolism, and immune activity. Recent research shows circadian clock genes can influence immune responses. Studies on SARS-CoV-2 and influenza show clock genes regulate viral entry, replication, and immune signaling. However, their role in infection risk, immune defense, replication dynamics, and disease outcomes remains undefined. This study evaluates how circadian rhythms regulate viral replication and immune responses in COVID-19 and other viral infections. This review utilized PubMed to identify articles from the past five years using the terms “(immunity) AND (circadian) AND (viruses OR virus OR viral).”After reviewing 149 abstracts, 44 peer-reviewed articles …

Differential Effects Of Testosterone And Estrogen On Inflammation And Disease Severity In Asthma And Copd, Samyslandine B. Eugene, Prisha Gupta, Srimayi Yeedara, Abdulwahab Eddib, Tanya Joseph, Tanmayee Maddineni

OneUSF Undergraduate Research Conference

Asthma is a chronic inflammatory disease characterized by airway hyperresponsiveness, and airflow obstruction, while Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory condition characterized by irreversible airflow limitation. Although previous research has examined hormonal influence, the specific effects of sex hormones in asthma and COPD remain unclear. This study aims to evaluate how testosterone and estrogen influence inflammation, disease severity and exacerbation frequency in adults with asthma and COPD. A comprehensive literature review using PubMed with keywords (asthma OR COPD) AND (sex hormones OR estrogen OR testosterone) AND (inflammation OR disease severity OR exacerbations) yielded 145 articles. After screening …

Functional And Phenotypic Analysis Of Kimona Gp55 And Gp56, Kyrillos E. Takla

OneUSF Undergraduate Research Conference

Bacteriophages encode many proteins with limited functional annotation, making it difficult to predict how individual gene products influence bacterial hosts. Phenotypic assays that directly test expressed proteins provide a more reliable way to assess biological function. Here, I evaluated the effects of Kimona phage proteins gp55 and gp56 following inducible expression in Mycobacterium smegmatis. Based on conserved sequence features, I hypothesized that gp55 functions as a DNA primase but lacks the metal-binding motif, whereas gp56 lacks the catalytic domains required for primase activity, and that neither protein would exhibit cytotoxic effects. Gene 55 encodes gp55, a 219-amino-acid protein containing core …

A Pooled Analysis Of Efficacy Outcomes Of Til In Advanced Mel Patients Treated At Moffitt Cancer Center, Joel Kuriakose

OneUSF Undergraduate Research Conference

Tumor-infiltrating lymphocyte (TIL) therapy induces durable responses in a subset of patients with metastatic melanoma, yet determinants of efficacy remain incompletely defined. We performed integrated immunophenotypic and spatial transcriptomic profiling of TIL infusion products and matched tumor microenvironments (TMEs) from patients treated in early-phase TIL-based trials at Moffitt Cancer Center. The objective response rate was 36%, with a median progression-free survival (PFS) of 10 months. Responders exhibited infusion products enriched for CD8⁺ T cells, stem-like memory (TSCM) CD8⁺ subsets, and LAG3⁺CD8⁺ T cells, along with enhanced TIL persistence in the periphery. Notably, prior exposure to immune checkpoint was associated with …

Testing Elicitors Of Homologous Jadr2 Proteins To Regulate Natural Product Production, Carzon J. Williams, Emilee A. Patterson, Allison S. Walker

SPARK Symposium Presentations

The growing threat of antimicrobial resistance (AMR) has and will contribute to global economic and public health concerns in the foreseeable future leading into 2050. As mortality rates derived from AMR are projected to reach 10 million if no viable solution is found to combat it through hastened drug discovery. The use of natural products to mitigate AMRs effects is viable as more than 50% of FDA approved drugs are natural products. These natural products are synthesized by biosynthetic gene clusters (BGC), found in bacteria with a regulatory protein not allowing transcription until unbound . Current methods of eliciting the …

Don't Self-Opt Out Of Career Opportunities: Proceed With Confidence, Valerie Mendoza

Faculty Publications

While reflecting on your career in the past, have you ever stepped back from an opportunity that you wanted because you doubted yourself? In the workplace, confidence often gets mistaken for competence, and that means talented employees can be overlooked simply because they hesitate. The truth is that confidence isn’t something you’re born with. It’s a skill you can build. This session will get you started on building that skill.

We’ll explore practical strategies to strengthen your confidence starting today. We’ll also break down the key differences between how confident individuals act compared to those who aren’t, so you can …

Fluency ≠ Literacy: Practical Strategies To Scaffold, Not Offload, Rachel Rupprecht, Heidi Keller, Vanessa Hörmann

Teaching & Learning with AI

This open-access resource kit helps faculty transition students from passive AI outsourcing to critical evaluation and essential skill cultivation. It includes 11 Assignment Templates & Rubrics, a Template Selector Gem, an AI Literacy Coach Gem, a Mindset Shifts & Expert Blind Spots visual guide, and student-facing resources.

The Effects Of Cinnamaldehyde On Tetrahymena Thermophila, Sydney Kurland

Publications and Research

In addition to their common use as spices in cooking and baking, cinnamon plants, Cinnamomum zeylanicum and Cinnamomum cassia for example, have long been used in herbal remedies worldwide. Cinnamon contains many vital oils and active compounds including cinnamaldehyde (CMD). Numerous studies looking at potential therapeutic effects of cinnamon have demonstrated its antioxidant, anti-inflammatory, and antimicrobial properties (1, 2, 3).   Therefore, it is important to continue studying the efficacy, benefits, and mechanisms of action of cinnamon and CMD to have a complete understanding of its full potential. Tetrahymena thermophila is a ciliated protozoan commonly used as a model organism to …

Investigation Of Molecular Interactions Between Peroxisome Biogenesis Factors Pex3 And Pex 19, Vania Hernandez

Linfield University Student Symposium: A Celebration of Scholarship and Creative Achievement

Peroxisome biogenesis disorders (PBDs) are caused by disrupted peroxisome formation, which impairs cellular metabolism, leading to poor muscle tone, seizures, hearing and vision loss, and skeletal abnormalities. Peroxisomes are small membrane-bound organelles that perform essential synthesis, breakdown, and detoxification reactions. Peroxisomes can be created through fission, the division of existing mature peroxisomes, or de novo biogenesis. In de novo biogenesis, the endoplasmic reticulum secretes vesicles containing peroxisomal proteins (peroxins) that recruit additional peroxins to form a mature peroxisome. PEX3 and PEX19 are peroxisomal biogenesis factors that interact to coordinate trafficking and import of peroxisomal membrane proteins (PMPs). The molecular nature …

Reframing Intimacy: An Occupation-Based Approach To Pelvic Floor & Sexual Health, Emma Stone

Occupational Therapy Capstone Presentations

Pelvic floor dysfunction is highly prevalent among women in the United States, and sexual health is often underaddressed in healthcare. This capstone project aimed to define the role of occupational therapists (OTs) in pelvic floor therapy and promote integration of sexual health into practice. Completed in an outpatient pelvic floor setting, the project included clinical skill development, program development, and advocacy. Interventions involved continuing education, creation of educational handouts, implementation of home exercise programs, and tracking outcomes using the PFDI-20. Additional initiatives included staff education and student training on OT’s role in pelvic health. All 12 tracked clients progressed toward …

The Role Of Mterf-3 In Mitochondrial Transcription, Reese C. Jones

Linfield University Student Symposium: A Celebration of Scholarship and Creative Achievement

The Mitochondrial Termination Factor (MTERF) family is a protein group of mitochondrial termination factors that are classified as regulators. Each MTERF protein has their own specialized role with respect to mitochondrial transcription, and not all are terminator factors. The protein group is based on sequence similarly, and the MTERF-3 protein is the most conserved of the family showing a crucial role across species. This is supported by the knockout mice exhibiting embryonic lethality when the gene is removed. Understanding the regulatory role of MTERF-3 and its interactions with the mitochondrial transcription machinery is the major aim of this project. To …

Nitrogen Limitation Impacts The Evolution Of Tobramycin Resistance In E.Coli, Anja Hofmeier

Undergraduate Research and Engagement Symposium

We are investigating how nutrient-limitation affects the evolution of antibiotic resistance in Escherichia coli. We evolved E. coli for 24 days in nitrogen- or carbon-limited environments with and without tobramycin. Many nitrogen-limited strains that evolved with tobramycin did not develop antibiotic resistance and went extinct. Surprisingly, fitness competitions showed that nitrogen-limited populations had an even larger fitness advantage in nitrogen-limited environments with tobramycin than in their evolutionary environments. These populations had a mutation in either gene glnL or glnK. We isolated each mutation in a clone and ran fitness assays to investigate how glnL and glnK mutations affected …

Towards A Unified Architecture For Jointly Learning Human And Robot Behavior, Nathan A C Hogg

Undergraduate Research and Engagement Symposium

General-purpose robotic manipulators will be maximally useful if they can be trained on existing data, such as pre-collected human footage. Recent advances in robot learning typically rely on visuals to mimic the high-fidelity movements of humans. Our goal is to model large datasets of human actions as sequences of goal-seeking behaviors, driving robotic motion by leveraging this understanding of human intent. This presentation will discuss the current state of robotic imitation learning, the advancements we have made over the past three months, and our future goals.

Assessment Of Lake Water Quality Parameters Using Uav Hyperspectral Imaging, Hasanul Banna, Taufiqa Tajnin

Publications and Research

Monitoring water quality in lakes is critical for assessing ecosystem health, managing drinking water resources, and detecting harmful algal blooms. Unmanned Aerial Vehicle (UAV)–based hyperspectral imaging provides a promising approach for high-resolution observation of water quality parameters. In this undergraduate research project, hyperspectral imagery collected over sample lakes within the Delaware River Watershed was processed using BaySpec’s CubeStitcher software to assess its capability to detect variations in chlorophyll-a (Chl-a) concentrations. This work was conducted as part of a National Fish and Wildlife Foundation (NFWF)-funded project in collaboration with Princeton Hydro and NYC College of New York. Hyperspectral image cubes were …

The Delivery Dilemma: Unintended Consequences Of Cesarean Sections, Cecilia Odegard, Ellie Rose Piette

Celebrating Scholarship and Creativity Day (2018-)

Cesarean sections (C-sections) are a major surgical procedure intended to minimize the rate of maternal and infant mortality due to complications during birth. While they were originally intended to only be performed when medically necessary, rates of non-medically indicated C-sections have increased significantly. This poster examines the unintended consequences (UICs) that are associated with C-section delivery, focusing on both short-term and long-term effects. A major focus is how C-sections disrupt early microbial exposure during birth, which plays an important role in the development of the infant gut microbiome and immune system. Research has shown that infants born via C- section …

Silicone Wristband Based Passive Sampling Methods Development And Evaluation For Use In Community Exposure Studies, Emily Broniewicz, Sophie Novak, Kenneth Brown, Julie Peller

Symposium on Research and Creative Expression (SORCE)

Indoor air quality is a critical determinant of human health, particularly in communities located near industrial activity, where residents experience disproportionate exposure to harmful pollutants and spend a greater proportion of time indoors. Outdoor sources of volatile organic compounds (VOCs) include emissions from industrial processes, vehicle exhaust, fuel storage, and manufacturing operations. Indoor environments further contribute to personal exposure, as they are emitted from building materials, paints, adhesives, carpets, furniture, cleaning agents, personal care products, and consumer electronics. Combined, these sources create complex exposure profiles associated with adverse health outcomes, including respiratory disease, neurological impairment, endocrine disruption, and cancer. As …

Vulnerability Of Bass Populations To Our Changing Climate In The Mississippi River, Cameron Schreifels

Celebrating Scholarship and Creativity Day (2018-)

Climate change is altering habitats and damaging bass populations throughout the Mississippi. The main factors of climate change affecting bass are shifts in water quality and significant weather events, which have increased bass vulnerability. With rising temperatures and eutrophication changing the way these bass hunt for their prey, it has made it easier for other non-native species to encroach on their habitat, which has led to bass further encroaching on other species due to climate change.  Given their economic importance and cultural significance, better management practices are needed to find new ways to protect them and ensure they remain a …

Survival Of The Fittest: Extremophilic Actinomycetes As The Future Of Antibiotic Treatment, Ben Reddan, Kyley Nelson

Celebrating Scholarship and Creativity Day (2018-)

The antibiotic resistance crisis is an emerging global health threat. In 2019 alone, 1.27 million deaths were attributed to antibiotic-resistant pathogens, and researchers predict the problem will worsen without intervention. Methicillin-Resistant Staphylococcus aureus (MRSA) has become a primary model for this crisis because it utilizes genomic adaptations to bypass β-lactam antibiotics. Although temperate actinomycetes have historically provided the majority of clinical antibiotics, recent bioprospecting has revealed that extremophilic actinomycetes represent a critical untapped resource. These organisms exhibit several adaptations to thrive in extreme environments, which results in the production of novel secondary metabolites and resilient extracellular enzymes. This literature review …

Mapping Mgmt Methylation Sites That May Predict Chemotherapy Success In Glioblastoma, Kennedy Bueno

Celebrating Scholarship and Creativity Day (2018-)

Glioblastoma is the most common malignant primary brain tumor in adults, with a median survival of 15 months post-diagnosis. Resistance to standard temozolomide (TMZ) chemotherapy is common and is strongly influenced by O6-methylguanine-DNA methyltransferase (MGMT), a DNA repair enzyme that reverses TMZ induced DNA damage. Reduced MGMT expression is associated with greater TMZ sensitivity and improved survival. Although MGMT promoter cytosine-phosphate-guanine dinucleotide (CpG) methylation is linked to treatment response, the individual CpG sites responsible for MGMT silencing remain unclear. This research aims to identify which sites are necessary to suppress MGMT expression and increase TMZ sensitivity. This project will map …

Peer Cultural Socialization As A Moderator Of Perceived Discrimination And Ethnic-Racial Identity Exploration Among Korean Adoptees, Josie Braun, Majel Baker, Jae-In Kim, Richard Lee, Elisheva Perelman

Celebrating Scholarship and Creativity Day (2018-)

As peers become increasingly salient sources of affirmation and cultural learning across adolescence and emerging adulthood, peer cultural socialization may play a distinct and critical role in moderating Korean adoptees' exploration of their ethnic-racial identity. This study hypothesized that 1) ethnic-racial discrimination experienced in the past year in adulthood (T3) will be unrelated to exploration of Korean ethnic-racial identity in adulthood (T3). However, peer racial socialization in adulthood (T3) will moderate the relationship between ethnic-racial discrimination experienced in adulthood (T3) and exploration of Korean ethnic-racial identity in adulthood (T3), and 2) ethnic-racial discrimination experienced in the past year in adulthood …